Isla Santa María Vacations from $395

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Your Isla Santa María Vacation

Amazing adventures await when you reserve a vacation package to Isla Santa María. Whether you're a foodie, history buff or just a traveler who loves to experience new places, there's something for everyone in this lively city. Post Office Bay is one of the top attractions to include on your sightseeing agenda during a trip to Isla Santa María. Expedia is here to help you escape the everyday. Tailor your vacation to Isla Santa María to suit your travel style, whatever that may be.

The Latest Isla Santa María vacation packages

Price found within the past 48 hours. Click for updated prices.
Galapagos Eco Friendly

Galapagos Eco Friendly

3 out of 5
Price was $557, price is now $395 per person
$395
per person
Mar 17 - Mar 21
found 2 hours ago
Roundtrip flight included
Guayaquil (GYE) to San Cristobal (SCY)
9.4/10 Exceptional! (201 reviews)
Had a wonderful stay with family at this hotel. Harry is a great host. The breakfast room upstairs has great views we enjoyed the delicious breakfast there.

Reviewed on Jan 2, 2026

Golden Bay Galapagos

Golden Bay Galapagos

3.5 out of 5
Save 100% on your flight
Price was $1,315, price is now $809 per person
$809
per person
Mar 17 - Mar 21
found 2 hours ago
Roundtrip flight included
Guayaquil (GYE) to San Cristobal (SCY)
9/10 Wonderful! (15 reviews)
The room spotless and Rafeal and Debra were fantastic hosts. We could not want for better hosts.

Reviewed on Nov 29, 2025

Hotel Albemarle Galapagos Beachfront

Hotel Albemarle Galapagos Beachfront

3.5 out of 5
Price was $2,138, price is now $1,447 per person
$1,447
per person
Mar 20 - Mar 26
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Isla Baltra (GPS)
9/10 Wonderful! (91 reviews)
The staff were wonderful and did everything possible to make sure our visit was perfect.

Reviewed on Jan 8, 2026

Galapagos Sunset Hotel

Galapagos Sunset Hotel

3 out of 5
Price was $691, price is now $495 per person
$495
per person
Mar 17 - Mar 21
found 2 hours ago
Roundtrip flight included
Guayaquil (GYE) to San Cristobal (SCY)
9.4/10 Exceptional! (168 reviews)
We had a wonderful stay at Sunset Galapagos Hotel in San Cristóbal. The hotel is perfectly situated right at the port, offering a great balance of lively daytime activity while remaining quiet and peaceful at night—ideal for a good night’s sleep. All of the staff were exceptionally friendly and helpful. Max, Joshua, and Antonia were always ready to answer questions, offer guidance, or help arrange transportation, which made our stay feel easy and well supported. Everything was immaculately clean, and we were very happy with our overall experience. We would absolutely recommend this hotel and would gladly stay here again.

Reviewed on Jan 9, 2026

Ikala Galapagos Hotel

Ikala Galapagos Hotel

4 out of 5
Price was $891, price is now $655 per person
$655
per person
Feb 27 - Mar 3
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.6/10 Exceptional! (124 reviews)
Great staff—very helpful. Nice room and good location.

Reviewed on Jan 3, 2026

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Discover the most popular places to visit in Isla Santa María

Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around.

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

Post Office Bay
Bedtime in the Galapagos #golden

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.

Punta Suarez

What to do in Isla Santa María

Learn about the history of Floreana

Full Day Floreana Tour

$220
per adult
Full Day Floreana Tour
Galapagos Enchanting 3 Islands

Galapagos Enchanting 3 Islands (5 Days)

$1,329
per adult
Galapagos Enchanting 3 Islands (5 Days)
Faune seeing at the snorkeling

Full Day Santa Fe Playa escondida snorkeling tour

$220
per adult
Full Day Santa Fe Playa escondida snorkeling tour
See all activities in Isla Santa María

Isla Santa María Hotel Deals

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $155 total per night from Jan 14 to Jan 15
$155 total
Jan 14 - Jan 15
9/10 Wonderful! (386 reviews)
This is a small, friendly hotel, well maintained and a modern pool area. It is located in a quiet road just a 10 min walk from the harbour and restaurants. Breakfast was a bit limited.

Reviewed on Jan 11, 2026

Hotel Fiesta
Capitan Max B&B

Capitan Max B&B

3 out of 5
Charles Binford St Puerto Ayora Galapagos
$79 nightly
The price is $79 total per night from Jan 15 to Jan 16
$79 total
Jan 15 - Jan 16
9.6/10 Exceptional! (203 reviews)
Stayed here again for a day before catching a flight. No frills accommodation but with all the essentials needed for a very comfortable stay. Captain Max helped with late checkout without asking any questions. Great place! Great location!

Reviewed on Dec 30, 2025

Capitan Max B&B
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
$73 nightly
The price is $73 total per night from Jan 19 to Jan 20
$73 total
Jan 19 - Jan 20
8.6/10 Excellent! (183 reviews)
We are extending our stay by one day. Excellent hotel if you are prepared for the 25 minute walk to the dock Charles Darwin Ave. It is USD2 per taxi otherwise.

Reviewed on Jan 8, 2026

Hotel el descanso del Guia
See all 210 properties in Isla Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Isla Santa María Vacation Packages

Isla Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

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Frequently asked questions

How much does an Isla Santa María vacation package cost?
You can grab a vacation package to this top destination from $395 on Expedia. However, how much your vacation to Isla Santa María costs will depend on factors like the season, length of stay and hotel choice.
What are the cheapest months to go to Isla Santa María?
January, August and December are great times to search for cheap Isla Santa María vacation packages. Traveling in less busy months means you can typically find reduced prices on flights and hotels.
How many days is enough for Isla Santa María?
The ideal length of your Isla Santa María vacation depends on what you'd like to see. Usually, a handful of days to a week will give you time to check out all the top sights and explore some hidden treasures along the way.
How to find the best Isla Santa María package deals?
Start your search for an Isla Santa María package deal by entering your travel dates and destination under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Isla Santa María package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Isla Santa Marían escape underway.
Is it cheaper to book an Isla Santa María vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically land a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Isla Santa María vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Isla Santa María?
If you have your Isla Santa María vacation dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Isla Santa María?

  1. Choose your travel dates: What you want to do in Isla Santa Marían and your preferred season will help you decide when to travel.
  2. Set a budget: Factor in costs such as transportation, flights and meals when working out how much to put aside for your trip to Isla Santa María. Then, select a property that matches your budget, whether that's an affordable option or a lavish getaway.
  3. Organize your Isla Santa María getaway with Expedia's trip planning tool: Look for and book stays and things to do all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Isla Santa María together.
  4. Decide your trip length: Think about how long you want to spend exploring Isla Santa María. Plan your days so you can get to all the attractions and experiences you're interested in at a leisurely pace.
  5. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that's left now is to pick an Isla Santa María vacation package that brings all your bookings together.
  6. Add on experiences and excursions: Read our dedicated travel guide to find some incredible things to do in Isla Santa María. Book tickets or make reservations before you go to save time and skip the hassle of searching for activities once you arrive.

Does Expedia offer Book Now, Pay Later Isla Santa María vacation packages?
If you're like us, you love jet-setting around the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Isla Santa María trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.