Isla Santa María Vacations from $594

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Your Isla Santa María Vacation

Amazing adventures await when you reserve a vacation package to Isla Santa María. Whether you're a foodie, history buff or just a traveler who loves to experience new places, there's something for everyone in this lively city. Post Office Bay is one of the top attractions to include on your sightseeing agenda during a trip to Isla Santa María. Expedia is here to help you escape the everyday. Tailor your vacation to Isla Santa María to suit your travel style, whatever that may be.

The Latest Isla Santa María vacation packages

Price found within the past 48 hours. Click for updated prices.
BAY VIEW HOUSE

BAY VIEW HOUSE

Save 100% on your flight
$594
per person
Oct 22 - Oct 27
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.6/10 Exceptional! (9 reviews)
Bay View Inn was right in the heart of town, yet the apartment felt peaceful and quiet. Spacious and well-kept, with a friendly, helpful host. Would definitely recommend!

Reviewed on Aug 11, 2026

Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton

Save 100% on your flight
$2,833
per person
Nov 17 - Nov 24
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Isla Baltra (GPS)
9.4/10 Exceptional! (61 reviews)
Hotel Albemarle Galapagos Beachfront

Hotel Albemarle Galapagos Beachfront

$1,004
per person
Oct 16 - Oct 20
found 9 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Isla Baltra (GPS)
9/10 Wonderful! (110 reviews)
Galapagos Sunset Hotel

Galapagos Sunset Hotel

$1,004
per person
Oct 16 - Oct 20
found 9 hours ago
Roundtrip non-stop flight included
Miami (MIA) to San Cristobal (SCY)
9.4/10 Exceptional! (212 reviews)
Hotel was beautiful and in the best location! The pier for tour pickup is right out front and everything is within walking distance. Max greeted us at check-in and was super friendly, knowledgeable, and helpful. The breakfast was great and filling, with an amazing rooftop view. The only negatives were: we had confirmed hotel pick-up, however no one was there when we arrived. I think just a miscommunication using the chat feature. The water pressure in the shower was low with no hot water, which was no biggie for us, but maybe a deal breaker for others. Would definitely recommend this hotel!

Reviewed on Aug 27, 2026

Palo Santo Galapagos Hotel

Palo Santo Galapagos Hotel

$603
per person
Nov 17 - Nov 20
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
8.6/10 Excellent! (23 reviews)
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Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
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Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.
Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
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What to do in Isla Santa María

Learn about the history of Floreana

Full Day Floreana Tour

$220
per adult
Full Day Floreana Tour
Private Snorkeling on Santa Fe Island and Hidden Beach with Lunch

Private Snorkeling on Santa Fe Island and Hidden Beach with Lunch

$155
per adult
Private Snorkeling on Santa Fe Island and Hidden Beach with Lunch
Santa Fe Island and Virgin Beach Private Tour with Lunch

Santa Fe Island and Virgin Beach Private Tour with Lunch

$170
per adult
Santa Fe Island and Virgin Beach Private Tour with Lunch
See all activities in Isla Santa María

Isla Santa María Hotel Deals

Hotel Fiesta

Hotel Fiesta

Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
$119 nightly
$119 total
Oct 4 - Oct 5
9/10 Wonderful! (433 reviews)
"Es un lindo hotel para quedarse, tiene piscina, hidromasaje y desayuno bufete incluido sin duda regresaría"

Reviewed on Sep 2, 2026

Hotel Fiesta
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

Barrio Punta Estrada Puerto Ayora Galapagos
$552 nightly
$607 total
Sep 9 - Sep 10
Finch Bay Galapagos Hotel
Maidith Galapagos Inn

Maidith Galapagos Inn

Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
$130 nightly
$130 total
Sep 5 - Sep 6
10/10 Exceptional! (157 reviews)
"Pros: quiet location but still a close walk to town, excellent rotating breakfast options, warm pool for the kids to play in, very clean and comfortable, lots of character! Cons: none, we loved it all!"

Reviewed on Aug 13, 2026

Maidith Galapagos Inn
See all 216 properties in Isla Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Isla Santa María Vacation Packages

Isla Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

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Frequently asked questions

How much does an Isla Santa María vacation package cost?
You can grab a vacation package to this top destination from $594 on Expedia. However, how much your vacation to Isla Santa María costs will depend on factors like the season, length of stay and hotel choice.
What are the cheapest months to go to Isla Santa María?
January, August and December are great times to search for cheap Isla Santa María vacation packages. Traveling in less busy months means you can typically find reduced prices on flights and hotels.
How many days is enough for Isla Santa María?
The ideal length of your Isla Santa María vacation depends on what you'd like to see. Usually, a handful of days to a week will give you time to check out all the top sights and explore some hidden treasures along the way.
How to find the best Isla Santa María package deals?
Start your search for an Isla Santa María package deal by entering your travel dates and destination under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Isla Santa María package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Isla Santa Marían escape underway.
Is it cheaper to book an Isla Santa María vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically land a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Isla Santa María vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Isla Santa María?
If you have your Isla Santa María vacation dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Isla Santa María?
  1. Choose your travel dates: What you want to do in Isla Santa Marían and your preferred season will help you decide when to travel.
  2. Set a budget: Factor in costs such as transportation, flights and meals when working out how much to put aside for your trip to Isla Santa María. Then, select a property that matches your budget, whether that's an affordable option or a lavish getaway.
  3. Organize your Isla Santa María getaway with Expedia's trip planning tool: Look for and book stays and things to do all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Isla Santa María together.
  4. Decide your trip length: Think about how long you want to spend exploring Isla Santa María. Plan your days so you can get to all the attractions and experiences you're interested in at a leisurely pace.
  5. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that's left now is to pick an Isla Santa María vacation package that brings all your bookings together.
  6. Add on experiences and excursions: Read our dedicated travel guide to find some incredible things to do in Isla Santa María. Book tickets or make reservations before you go to save time and skip the hassle of searching for activities once you arrive.
Does Expedia offer Book Now, Pay Later Isla Santa María vacation packages?
If you're like us, you love jet-setting around the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Isla Santa María trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.