Isla Santa María Vacations from $520
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Your Isla Santa María Vacation
Amazing adventures await when you reserve a vacation package to Isla Santa María. Whether you're a foodie, history buff or just a traveler who loves to experience new places, there's something for everyone in this lively city. Post Office Bay is one of the top attractions to include on your sightseeing agenda during a trip to Isla Santa María. Expedia is here to help you escape the everyday. Tailor your vacation to Isla Santa María to suit your travel style, whatever that may be.
The Latest Isla Santa María vacation packages
Price found within the past 48 hours. Click for updated prices.
BAY VIEW HOUSE
$571
per person
Jan 11 - Jan 15
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
8.8/10 Excellent! (10 reviews)
The location was great and very convenient. Unfortunately, our apartment faced the main street, so there was quite a bit of traffic and street noise, especially at night. It did make it difficult to sleep, so if you’re a light sleeper, I would recommend requesting an apartment away from the main street.
Reviewed on Sep 19, 2026
Hotel Isamar Galapagos Beachfront
$688
per person
Jan 11 - Jan 15
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9/10 Wonderful! (68 reviews)
Wonderful hotel and great location! Very affordable compared to others on the island. My family loved the quiet beach and the staff were very helpful. I would highly recommend to anyone going to Isla Isabela.
Reviewed on Sep 28, 2026
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View all tripsStay near popular Isla Santa María attractions
Photo by Tove Martin
Post Office Bay
Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
Photo by Delen Wong
Punta Suarez
Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
What to do in Isla Santa María
Santa Fe Island and Virgin Beach Private Tour with Lunch
$170
per adult
Isla Santa María Hotel Deals
Hotel Fiesta
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
$131 nightly
$131 total
Nov 19 - Nov 20
9/10 Wonderful! (450 reviews)
"We had a great stay. Quiet and close to everything"
Reviewed on Oct 13, 2026
Hotel el descanso del Guia
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
$73 nightly
$73 total
Nov 3 - Nov 4
8.8/10 Excellent! (235 reviews)
"All the staff were wonderful and very helpful. The breakfast was great and offered a good amount of food. Eric was the best and helped us navigate getting around the island. I would definitely stay at this hotel again."
Reviewed on Oct 16, 2026
Maidith Galapagos Inn
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
$117 nightly
$117 total
Oct 31 - Nov 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Isla Santa María Vacation Packages
Isla Santa Marían Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
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Frequently asked questions
How much does an Isla Santa María vacation package cost?
You can grab a vacation package to this top destination from $520 on Expedia. However, how much your vacation to Isla Santa María costs will depend on factors like the season, length of stay and hotel choice.
What are the cheapest months to go to Isla Santa María?
January, August and December are great times to search for cheap Isla Santa María vacation packages. Traveling in less busy months means you can typically find reduced prices on flights and hotels.
How many days is enough for Isla Santa María?
The ideal length of your Isla Santa María vacation depends on what you'd like to see. Usually, a handful of days to a week will give you time to check out all the top sights and explore some hidden treasures along the way.
How to find the best Isla Santa María package deals?
Start your search for an Isla Santa María package deal by entering your travel dates and destination under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Isla Santa María package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Isla Santa Marían escape underway.
Is it cheaper to book an Isla Santa María vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically land a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Isla Santa María vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Isla Santa María?
If you have your Isla Santa María vacation dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Isla Santa María?
- Choose your travel dates: What you want to do in Isla Santa Marían and your preferred season will help you decide when to travel.
- Set a budget: Factor in costs such as transportation, flights and meals when working out how much to put aside for your trip to Isla Santa María. Then, select a property that matches your budget, whether that's an affordable option or a lavish getaway.
- Organize your Isla Santa María getaway with Expedia's trip planning tool: Look for and book stays and things to do all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Isla Santa María together.
- Decide your trip length: Think about how long you want to spend exploring Isla Santa María. Plan your days so you can get to all the attractions and experiences you're interested in at a leisurely pace.
- Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that's left now is to pick an Isla Santa María vacation package that brings all your bookings together.
- Add on experiences and excursions: Read our dedicated travel guide to find some incredible things to do in Isla Santa María. Book tickets or make reservations before you go to save time and skip the hassle of searching for activities once you arrive.
Does Expedia offer Book Now, Pay Later Isla Santa María vacation packages?
If you're like us, you love jet-setting around the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Isla Santa María trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
