Lafayette Square Vacations from $598

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Lafayette Square Vacation

Take the stress out of travel planning with a Lafayette Square vacation package. With all the details organized before you go, all that's left to do is enjoy this food-lovers neighborhood's distilleries and craft breweries, cafes and bars and pubs. Wondering what to see and do during your trip to Lafayette Square? Nearby attractions such as Busch Stadium, Gateway Arch and Dome at America’s Center are excellent places to start. Expedia is here to help put your travel plans into action. Book your ideal Lafayette Square vacation now.

The Latest Lafayette Square Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $887, price is now $598 per person
$598
per person
Apr 24 - Apr 26
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Great place to stay! We arrived later at night around 11pm and the front desk gal working at that time was wonderful. Nice, quiet, clean and in a very nice area.

Reviewed on Feb 27, 2026

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4 out of 5
Downtown St. Louis
Price was $808, price is now $629 per person
$629
per person
Apr 24 - Apr 26
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to St. Louis (STL)
8.8/10 Excellent! (458 reviews)
Not the best and not the

Reviewed on Feb 24, 2026

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed

4 out of 5
Central West End
Price was $1,266, price is now $991 per person
$991
per person
Apr 11 - Apr 17
found 24 hours ago
Roundtrip flight included
Baltimore (BWI) to St. Louis (STL)
8.6/10 Excellent! (10 reviews)
Clean room nice area

Reviewed on Feb 1, 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
Clayton
Price was $1,220, price is now $985 per person
$985
per person
Apr 11 - Apr 17
found 24 hours ago
Roundtrip flight included
Baltimore (BWI) to St. Louis (STL)
9/10 Wonderful! (894 reviews)
Friendly staff, enjoyed our stay.

Reviewed on Feb 22, 2026

Hermann Grain Bins BNB

Hermann Grain Bins BNB

2 out of 5
Save 100% on your flight
Price was $1,788, price is now $1,460 per person
$1,460
per person
Apr 11 - Apr 17
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
2/10 (1 review)

Where to stay in Lafayette Square

Find the best Lafayette Square areas and neighborhoods for the activities you enjoy most. Learn more about Lafayette Square
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Lafayette Square Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Mar 5 to Mar 6
$111 total
Mar 5 - Mar 6
Total with taxes and fees
8.8/10 Excellent! (1,854 reviews)
All the staff were nice, and the room was clean. The air conditioning unit is very loud and you could hear everything in the hall. I would request a room away from the elevator.

Reviewed on Feb 28, 2026

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Mar 23 to Mar 24
$153 total
Mar 23 - Mar 24
Total with taxes and fees
9/10 Wonderful! (1,629 reviews)
Great place to stay. I recommend it and will stay again.

Reviewed on Feb 27, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Mar 29 to Mar 30
$122 total
Mar 29 - Mar 30
Total with taxes and fees
8.8/10 Excellent! (3,089 reviews)
Staff Checking in was quick and easy.

Reviewed on Feb 27, 2026

Clayton Plaza Hotel & Extended Stay
See all 1,823 properties in Lafayette Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Lafayette Square

Union Station, St. Louis, MO

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
St. Louis Cardinals Baseball.

Busch Stadium

4.5/5(1,469 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium
Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$30
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.