Lake Nona Medical City Vacations from $314
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Your Lake Nona Medical City Vacation
Our Lake Nona Medical City vacation packages are a simple and practical way to plan and book your next adventure. Experience the magic of this unique neighborhood without the hassle of organizing everything yourself. Need ideas about what to see during your trip to Lake Nona Medical City? University of Central Florida College of Medicine and Sanford-Burnham Medical Research Institute are two nearby attractions to stick on your to-do list. Don't just dream it — turn it into a reality! Lock in your perfect Lake Nona Medical City vacation with Expedia and experience travel your way.
The Latest Lake Nona Medical City Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Meliá Orlando Celebration
Save 100% on your flight
Price was $641, price is now $314 per person
$314
per person
Nov 4 - Nov 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8.6/10 Excellent! (1,520 reviews)
We arrived late and service was good.
Also, excellent choice of live music.
Reviewed on Sep 2, 2025
Westgate Palace Hotel / Universal / I-Drive
International Drive District
Price was $1,336, price is now $512 per person
$512
per person
Nov 15 - Nov 22
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8.8/10 Excellent! (1,008 reviews)
Being able to text the front desk for my needs was very helpful! Staff was friendly and the Universal shuttles were convenient.
Reviewed on Aug 30, 2025
Westgate Town Center Resort
Price was $799, price is now $350 per person
$350
per person
Nov 4 - Nov 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8/10 Very Good! (1,346 reviews)
First off the front desk needs retraining they gave us the completly incorrect room. Second the correct room the ceiling leaked. Third room was not properly cleaned the pull out sofa had visible crumbs and the ac unit was inoperable. The final upgraded room was extremely excellent.
Reviewed on Sep 1, 2025
The Delaney Hotel
South Orange
Price was $1,719, price is now $845 per person
$845
per person
Nov 5 - Nov 10
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
9.6/10 Exceptional! (1,009 reviews)
This is probably the 8th time staying in this hotel. It’s wonderful. Always a great choice. The restaurant in the hotel is great too. Food is consistently good as is the service. Amir who works in the restaurant was so eager to please. Friendly, professional and a good server.
Reviewed on Sep 1, 2025
Where to stay in Lake Nona Medical City
Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive District
1 out of top 10 points of interest in this area
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Medical City Hotel Deals
Marriott's Grande Vista
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $98 total per night from Sep 24 to Sep 25
$98 total
Sep 24 - Sep 25
Total with taxes and fees
Universal's Cabana Bay Beach Resort
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $158 total per night from Sep 29 to Sep 30
$158 total
Sep 29 - Sep 30
Total with taxes and fees
Holiday Inn Resort Kissimmee by the Parks by IHG
3011 Maingate Ln, Kissimmee, FL
Fully refundable
$73 nightly
The price is $83 total per night from Sep 7 to Sep 8
$83 total
Sep 7 - Sep 8
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona Medical City
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Universal Orlando Resort Express Passes
$149
per traveler
84% of travellers recommend
90 Minute Open Jump at a Trampoline Park in Kissimmee
$23
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.