Lake Nona Medical City Vacations from $183
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Your Lake Nona Medical City Vacation
Our Lake Nona Medical City vacation packages are a simple and practical way to plan and book your next adventure. Experience the magic of this unique neighborhood without the hassle of organizing everything yourself. Need ideas about what to see during your trip to Lake Nona Medical City? University of Central Florida College of Medicine and Sanford-Burnham Medical Research Institute are two nearby attractions to stick on your to-do list. Don't just dream it — turn it into a reality! Lock in your perfect Lake Nona Medical City vacation with Expedia and experience travel your way.
The Latest Lake Nona Medical City Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Palace Hotel / Universal / I-Drive
International Drive District
per person
Sep 14 - Sep 20
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8.6/10 Excellent! (1,002 reviews)
Very family friendly. I stayed with my kids, partner and mom and we loved that it was clean , safe and the staff was approachable
Reviewed on Jul 14, 2025
Westgate River Ranch Resort & Rodeo
Save 100% on your flight
per person
Aug 14 - Aug 20
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8/10 Very Good! (354 reviews)
Nice place. Kids had a good time. Not encouraged to go there if you are a minority. You wont feel welcomed. The staff is great, but the type of people that go there arent really folks that likely share the same interests as you do. There are Confederate flags all over; etc. Hotel rooms are no bueno, old. IF you want something nice, you need to spend the money glamping or have your own trailer.
Reviewed on Jun 24, 2025
Westgate Lakes Resort & Spa Universal Studios Area
per person
Sep 14 - Sep 20
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8.2/10 Very Good! (5,060 reviews)
The property was good and nice but the water park in some areas were way too expensive
Reviewed on Jul 15, 2025
Where to stay in Lake Nona Medical City
Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive District
1 out of top 10 points of interest in this area
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Medical City Hotel Deals
Hyatt Regency Orlando International Airport
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $229 total per night from Jul 21 to Jul 22
$229 total
Jul 21 - Jul 22
Total includes taxes and fees
9.4/10 Exceptional! (3,383 reviews)
"Beautiful property, conveniently located I Terminal B. Excellent food."
Reviewed on Jul 15, 2025
DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Aug 4 to Aug 5
$95 total
Aug 4 - Aug 5
Total includes taxes and fees
8.2/10 Very Good! (6,474 reviews)
"Convenient for visiting Iniversal, large rooms with great beds, lovely large pool area, helpful staff, could have more and better restaurants or addition food options. Very useable transportation to Universal."
Reviewed on Jul 15, 2025
Marriott's Grande Vista
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Aug 5 to Aug 6
$107 total
Aug 5 - Aug 6
Total includes taxes and fees
8.8/10 Excellent! (2,625 reviews)
"This hotel was excellent. It is close to all the attractions. Has a resort-like feel with many amenities during the day & night. The staff was also friendly. Hotel was clean. I would recommending staying here if you have a family or just coupling up, this place was great."
Reviewed on Jul 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona Medical City
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Florida: 90 Minute Everglades Cruise
$50
per adult
100% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.