Lake Nona Vacations from $243
Book a Hotel + Flight or Car together to unlock savings
Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Town Center Resort
Price was $809, price is now $380 per person
$380
per person
Mar 1 - Mar 7
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8/10 Very Good! (1,367 reviews)
Room was very spacious and clean upon arrival. Was able to checkin a hr early and the resort has very many amenities. The mexican restaurants brunch was 5 stars. Will definitely be back!
Reviewed on Jan 25, 2026
Margaritaville Cottages Orlando with H2O Waterpark by Vstays
Save 100% on your flight
Price was $1,257, price is now $687 per person
$687
per person
Apr 13 - Apr 17
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
9.2/10 Wonderful! (1,001 reviews)
We stayed in a cottage, and it was immaculate. Everyone was very friendly and helpful. We are excited about returning!!
Reviewed on Jan 25, 2026
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
1 out of top 10 points of interest in this area
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $130 total per night from Feb 22 to Feb 23
$130 total
Feb 22 - Feb 23
Total with taxes and fees
9.2/10 Wonderful! (4,363 reviews)
Was a very nice room, with a great
Reviewed on Jan 20, 2026
DoubleTree by Hilton Hotel Orlando at SeaWorld
10100 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Feb 22 to Feb 23
$107 total
Feb 22 - Feb 23
Total with taxes and fees
7.4/10 Good! (6,454 reviews)
I loved the amenities.
Reviewed on Jan 23, 2026
DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd Orlando FL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $119 total per night from Feb 25 to Feb 26
$119 total
Feb 25 - Feb 26
Total with taxes and fees
8.4/10 Very Good! (6,939 reviews)
Our room was clean and cozy, loved our stay. Staff was friendly and helpful as well
Reviewed on Jan 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Universal Orlando Resort Express Passes
$149
per traveler
86% of travellers recommend
90 Minute Open Jump at a Trampoline Park in Kissimmee
$23
per adult
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- VA Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.