Lake Nona Vacations from $286
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Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Towers Resort
Save 100% on your flight
Price was $709, price is now $349 per person
$349
per person
Mar 12 - Mar 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Orlando (MCO)
8.6/10 Excellent! (1,002 reviews)
Clean rooms, full equipped kitchen, spotless rooms. Definitely will stay here again
Reviewed on Jan 18, 2026
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
1 out of top 10 points of interest in this area
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
DoubleTree by Hilton Hotel Orlando at SeaWorld
10100 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Feb 8 to Feb 9
$112 total
Feb 8 - Feb 9
Total with taxes and fees
7.4/10 Good! (6,406 reviews)
The breakfast is good. The environment is quite.
Reviewed on Jan 18, 2026
Rosen Inn at Pointe Orlando
9000 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $85 total per night from Feb 8 to Feb 9
$85 total
Feb 8 - Feb 9
Total with taxes and fees
8.4/10 Very Good! (5,549 reviews)
Very CLEAN room!
Reviewed on Jan 17, 2026
Orlando International Drive North Hotel
5859 American Way Orlando FL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $83 total per night from Jan 21 to Jan 22
$83 total
Jan 21 - Jan 22
Total with taxes and fees
7.2/10 Good! (2,651 reviews)
Breakfast was better than expected. Staff was friendly. I would book again, but will ask for a cleaner room.
Reviewed on Jan 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Florida: 90 Minute Everglades Cruise
$55
per adult
100% of travellers recommend
90 Minute Open Jump at a Trampoline Park in Kissimmee
$23
per adult
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- VA Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.