Lake Nona Vacations from $226

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Your Lake Nona Vacation

Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.

The Latest Lake Nona Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Westgate Palace Hotel / Universal / I-Drive
ette hotel
Westgate River Ranch Resort & Rodeo
Westgate Vacation Villas Resort
The Delaney Hotel

Where to stay in Lake Nona

Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona

Lake Nona Hotel Deals

DoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando
4 out of 5
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Aug 4 to Aug 5
$95 total
Aug 4 - Aug 5
Total includes taxes and fees
8.2/10 Very Good! (6,436 reviews)
"Excelent hotel"

Reviewed on Jul 10, 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
Hyatt Regency Orlando International Airport
Hyatt Regency Orlando International Airport
4 out of 5
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $219 total per night from Jul 16 to Jul 17
$219 total
Jul 16 - Jul 17
Total includes taxes and fees
9.4/10 Exceptional! (3,353 reviews)
"Great location and stay"

Reviewed on Jul 9, 2025

Hyatt Regency Orlando International Airport
Marriott's Grande Vista
Marriott's Grande Vista
4 out of 5
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Aug 3 to Aug 4
$107 total
Aug 3 - Aug 4
Total includes taxes and fees
8.8/10 Excellent! (2,602 reviews)
"Enjoyed our stay!"

Reviewed on Jul 9, 2025

Marriott's Grande Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Lake Nona

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.