Lake Nona Vacations from $259
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Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Margaritaville Cottages Orlando with H2O Waterpark by Vstays
Price was $1,946, price is now $813 per person
$813
per person
Apr 22 - Apr 29
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
9.2/10 Wonderful! (1,001 reviews)
Sound system didn't work, or had been removed. Outside pool alarm didn't work, so it would go off every time we went inside from the pool. Otherwise, nice quiet area with a lot of things to do.
Reviewed on Feb 3, 2026
Westgate Town Center Resort
Price was $634, price is now $270 per person
$270
per person
Apr 8 - Apr 12
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8/10 Very Good! (1,367 reviews)
Room was amazing, all though the jacuzzi jets were dirty so once i turned them on the water got really gross. They need to do better at cleaning. I was certainly disappointed because i got the room for the jacuzzi and didn’t get to use it because it was filthy.
Reviewed on Feb 5, 2026
Flamingo Inn Beachfront
Price was $795, price is now $346 per person
$346
per person
Mar 20 - Mar 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8.6/10 Excellent! (978 reviews)
It was clean and although it looks a little older everything was very well taken care off and everything worked perfectly. I can honestly say it was the best hotel I’ve stayed where the AC worked extremely well. For the first time I had to actually turn off cause I was too cold which is odd to say. The property manager was very nice and helpful.
Reviewed on Jan 26, 2026
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr Orlando FL
$115 nightly
The price is $130 total per night from Feb 26 to Feb 27
$130 total
Feb 26 - Feb 27
Total with taxes and fees
9.2/10 Wonderful! (4,474 reviews)
Extremely comfortable suite, very clean, beautiful grounds and pool, great staff.
Reviewed on Feb 1, 2026
Rosen Inn at Pointe Orlando
9000 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $87 total per night from Feb 21 to Feb 22
$87 total
Feb 21 - Feb 22
Total with taxes and fees
8.4/10 Very Good! (5,653 reviews)
Good
Reviewed on Feb 2, 2026
DoubleTree by Hilton Hotel Orlando at SeaWorld
10100 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $118 total per night from Feb 22 to Feb 23
$118 total
Feb 22 - Feb 23
Total with taxes and fees
7.4/10 Good! (6,521 reviews)
Everything was perfect. The Staff was very helpful. I don't have any complaints. Can't wait to come back and stay there. We won't stay anywhere else. Thank you for an amazing stay
Reviewed on Feb 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Universal Orlando Resort Express Passes
$149
per traveler
86% of travellers recommend
90 Minute Open Jump at a Trampoline Park in Kissimmee
$23
per adult
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- VA Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.