Lake Nona Vacations from $308
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Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Blue Tree Resort in Lake Buena Vista
Price was $671, price is now $349 per person
$349
per person
Apr 23 - Apr 28
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8.4/10 Very Good! (1,002 reviews)
Very friendly and helpful staff. The room and site facilities were really clean and well maintained. Great location for all parks and restaurants. Will definitely be coming back!
Reviewed on Feb 6, 2026
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr Orlando FL
$131 nightly
The price is $148 total per night from Mar 1 to Mar 2
$148 total
Mar 1 - Mar 2
Total with taxes and fees
9.2/10 Wonderful! (4,517 reviews)
The room was clean and comfortable and they tried to accommodate our requests to the best of their ability. No late check out, even with an early request which is hard when you have late flights. Have stayed here multiple times and have never had them say yes. Other than that it’s a lovely place ...
Reviewed on Feb 5, 2026
Hyatt Regency Orlando International Airport
9300 Jeff Fuqua Boulevard Orlando FL
Fully refundableReserve now, pay when you stay
$252 nightly
The price is $284 total per night from Mar 4 to Mar 5
$284 total
Mar 4 - Mar 5
Total with taxes and fees
9.4/10 Exceptional! (3,967 reviews)
The room was wonderful, and the view was nice. I’d give it 4.75 stars—only because of noise. It’s not the hotel’s fault. They have quiet signs posted. I could hear the people next door and people walking down the hall on and off all night. That’s not really fixable, but it did wake me a few times. ...
Reviewed on Feb 1, 2026
Universal's Cabana Bay Beach Resort
6550 Adventure Way Orlando FL
$133 nightly
The price is $150 total per night from Feb 10 to Feb 11
$150 total
Feb 10 - Feb 11
Total with taxes and fees
8.8/10 Excellent! (6,285 reviews)
Room was ok. Everything you need is there
Reviewed on Feb 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona
Nemours Children's Hospital
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
VA Medical Center at Lake Nona
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Universal Orlando Resort Express Passes
$149
per traveler
86% of travellers recommend
90 Minute Open Jump at a Trampoline Park in Kissimmee
$23
per adult
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- VA Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.