Lake Nona Vacations from $226
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Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Palace Hotel / Universal / I-Drive
International Drive District
Save 100% on your flight
per person
Sep 12 - Sep 14
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8.6/10 Excellent! (1,002 reviews)
Good choice to stay, close to universal and not that far from disney.
I would definetly recomend it.
Excelent service.
Reviewed on Jul 10, 2025
Westgate River Ranch Resort & Rodeo
per person
Aug 14 - Aug 20
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
8/10 Very Good! (354 reviews)
Nice place. Kids had a good time. Not encouraged to go there if you are a minority. You wont feel welcomed. The staff is great, but the type of people that go there arent really folks that likely share the same interests as you do. There are Confederate flags all over; etc. Hotel rooms are no bueno, old. IF you want something nice, you need to spend the money glamping or have your own trailer.
Reviewed on Jun 24, 2025
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
1 out of top 10 points of interest in this area
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Aug 4 to Aug 5
$95 total
Aug 4 - Aug 5
Total includes taxes and fees
8.2/10 Very Good! (6,436 reviews)
"Excelent hotel"
Reviewed on Jul 10, 2025
Hyatt Regency Orlando International Airport
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $219 total per night from Jul 16 to Jul 17
$219 total
Jul 16 - Jul 17
Total includes taxes and fees
9.4/10 Exceptional! (3,353 reviews)
"Great location and stay"
Reviewed on Jul 9, 2025
Marriott's Grande Vista
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Aug 3 to Aug 4
$107 total
Aug 3 - Aug 4
Total includes taxes and fees
8.8/10 Excellent! (2,602 reviews)
"Enjoyed our stay!"
Reviewed on Jul 9, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Fort Meade: Bamboo Dune Buggy Tour
$70
per adult
100% of travellers recommend
Florida: 90 Minute Everglades Cruise
$50
per adult
100% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- VA Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.