A wooden pergola structure with a concrete base, surrounded by a chain-link fence and lush greenery.

Lake Nona Vacations from $329

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Lake Nona Vacation

Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.

The Latest Lake Nona Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 10 - Jan 16

    Westgate Vacation Villas Resort + Flight

    Kissimmee
    6 nights
    4.0 star property
    8.2/10 - Very good (2,130 reviews)
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - PSM • Nonstop
    $706
    $329
    per traveler
    found 1 day ago
    Westgate Vacation Villas Resort
  • Jan 10 - Jan 16

    Seasons Kissimmee - Orlando - Lake Buena Vista South, Florida Resort + Flight

    Kissimmee
    6 nights
    2.0 star property
    9.0/10 - Wonderful (4,081 reviews)
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - PSM • Nonstop
    $831
    $366
    per traveler
    found 1 day ago
    Seasons Kissimmee - Orlando - Lake Buena Vista South, Florida Resort
  • Dec 14 - Dec 19

    Disney's Animal Kingdom Lodge + Flight

    Bay Lake
    5 nights
    4.5 star property
    9.0/10 - Wonderful (1,001 reviews)
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - BOS • 1 stop
    $3,140
    $1,583
    per traveler
    found 1 day ago
    Disney's Animal Kingdom Lodge
  • Jan 24 - Jan 28

    Westgate Cocoa Beach Resort + Flight

    Cocoa Beach
    4 nights
    4.0 star property
    8.6/10 - Excellent (577 reviews)
    "Great place!"
    Reviewed November 2, 2026
    Roundtrip • New York (NYC) - Orlando (MCO)
    LGA - MCO • Nonstop MCO - LGA • Nonstop
    $1,050
    $540
    per traveler
    found 22 hours ago
    Westgate Cocoa Beach Resort
  • Jan 17 - Jan 23

    Westgate Towers Resort + Flight

    Kissimmee
    6 nights
    3.5 star property
    8.6/10 - Excellent (1,001 reviews)
    "La limpieza fue excelente"
    Reviewed October 28, 2026
    Roundtrip • New York (EWR) - Orlando (MCO)
    EWR - MCO • Nonstop MCO - EWR • Nonstop
    $747
    $384
    per traveler
    found 11 hours ago
    Westgate Towers Resort

Where to stay in Lake Nona

Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
Learn more about Lake Nona

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Reunion

The waterparks and pristine golf courses are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Discover the most popular places to visit in Lake Nona

What to do near Lake Nona

Lake Nona Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.