Lake Nona Vacations from $356
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Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Town Center Resort
Save 100% on your flight
Price was $797, price is now $356 per person
$356
per person
Jun 13 - Jun 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8.2/10 Very Good! (1,554 reviews)
$25 dollars for person to enter the water park. That’s insane.
Reviewed on Apr 12, 2026
Westgate Palace Hotel / Universal / I-Drive
International Drive District
Price was $1,446, price is now $608 per person
$608
per person
Jun 13 - Jun 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8.8/10 Excellent! (1,233 reviews)
Everyone was helpful and kind!
Reviewed on Apr 12, 2026
Westgate Vacation Villas Resort
Save 100% on your flight
Price was $797, price is now $370 per person
$370
per person
May 23 - May 30
found 2 days ago
Roundtrip flight included
Boston (BOS) to Orlando (MCO)
8/10 Very Good! (1,836 reviews)
I had to wait three hours for check-in didn’t get checked in till 6 o’clock that afternoon . They are over booking and under staff.
Reviewed on Apr 12, 2026
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $139 total per night from May 5 to May 6
$139 total
May 5 - May 6
Total with taxes and fees
9.2/10 Wonderful! (5,163 reviews)
Clean room. Had washer and dryer!
Reviewed on Apr 13, 2026
Universal's Cabana Bay Beach Resort
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $150 total per night from May 10 to May 11
$150 total
May 10 - May 11
Total with taxes and fees
9/10 Wonderful! (6,659 reviews)
Buen hotel. Habitaciones súper limpias y muy buena atención
Reviewed on Apr 13, 2026
Hyatt Regency Orlando International Airport
9300 Jeff Fuqua Boulevard Orlando FL
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $258 total per night from Apr 26 to Apr 27
$258 total
Apr 26 - Apr 27
Total with taxes and fees
9.4/10 Exceptional! (4,112 reviews)
The staff were polite, knowledgeable, courteous. The room was clean.
Reviewed on Apr 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Lake Nona
VA Medical Center at Lake Nona
4/5(13 reviews)
Though VA Medical Center at Lake Nona might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
Nemours Children's Hospital
4/5(5 reviews)
Though Nemours Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Things to do
Florida: 90 Minute Everglades Cruise
$55
per adult
100% of travellers recommend
Rock Hard Revue | The #1 Male Revue in Fl | General Admission
$25
per adult
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- Va Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.