Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Start by selecting your hotel
Start by selecting your hotel
Start by selecting your hotel

Save up to $603 by booking Flight + Hotel.

Search 590,000 properties and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more


Lake Nona Vacation Packages

Lake Nona is a part of Orlando, a significant city that is home to 240,000 residents.

Save Time and Money with a Lake Nona Package Deal

Save when you purchase flight and hotel packages via Expedia. Booking your desired flights and lodgings are the necessary ingredients for a good vacation. Combining them together with us into one package deal is a sure-fire recipe that takes out the stress and saves you money. Have more fun on your Lake Nona trip with the extra cash.

Savings of up to $583 are available to savvy vacationers who book a package deal.

With 400 airline partners and about 321,000 worldwide hotels, our exhaustive database will get you to your desired destination.

Imagine how much extra money you'll have with some of the top prices and deals via Expedia.

You can alter your vacation plans with us because we do not charge cancellation fees for almost all of our bookings.

Lake Nona Vacation Packages

If you're going to Lake Nona from the city center, it's 12 miles to the southeast. Alternatively, it's 3 miles southeast of Orlando International Airport.

Start off by seeing a few close by tourist attractions, including Split Oak Forest Mitigation Park and Back to Nature Wildlife Refuge. David Leadbetter Golf Academy and East Lake Fish Camp are also worth going to. To experience a different side of Orlando, head to the nearby neighborhoods Lake Nona Medical City and Lake Hart.

You really shouldn't miss an opportunity to stop at Universal Studios Orlando. You'll find it 7 miles from the heart of the city.

Hit the greens at the nearby courses, such as North Shore Golf Club and Eagle Creek Golf Club. Fine tune your putting and then go to the clubhouse for a few cold ones.

Accommodation in Lake Nona

Pre-booking the perfect hotel or apartment is crucial if you are after a laid-back getaway. Discover the best located and most popular Lake Nona accommodation options on Expedia's up-to-date lodging guide.

Looking at the premium end of the spectrum, check out the latest Expedia deals at the Hyatt Regency Orlando International Airport, at 9300 Jeff Fuqua Boulevard, or the Orlando Airport Marriott Lakeside, at 7499 Augusta National Dr. The Sleep Inn & Suites Orlando International Airport, at 1700 Mccoy Rd, and the La Quinta Inn Orlando Airport West, at 7931 Daetwyler Dr are two cheaper options worth considering if you're looking to save a bit of cash.

*Savings based on all vacation package bookings with Flight + Hotel on Expedia.com from January through December 2017, as compared to price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.


Top Hotel Deals

See all 2,854 Properties in Lake Nona
Courtyard Orlando Lake Nona
Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona

6955 Lake Nona Boulevard, Orlando
     
    4.7
    of 5, from 184 reviews
    3.0 out of 5.0

    Located in Lake Nona, this hotel is within a 10-minute walk of University of Central Florida College of Medicine and VA Medical Center at Lake Nona. Nemours Children's Hospital and Sanford-Burnham Medical Research Institute are also within 1 mi (2 km).

    Residence Inn Orlando Lake Nona
    Residence Inn Orlando Lake Nona

    Residence Inn Orlando Lake Nona

    6955 Lake Nona Blvd, Orlando
       
      4.7
      of 5, from 77 reviews
      3.0 out of 5.0

      Located in Lake Nona, this hotel is within a 10-minute walk of University of Central Florida College of Medicine and VA Medical Center at Lake Nona. Nemours Children's Hospital and Sanford-Burnham Medical Research Institute are also within 1 mi (2 km).

      B Resort and Spa located in Disney Springs® Resort Area $77
      B Resort and Spa located in Disney Springs® Resort Area

      B Resort and Spa located in Disney Springs® Resort Area

      1905 Hotel Plaza Blvd, Lake Buena Vista
         
        4.1
        of 5, from 3,580 reviews
        4.0 out of 5.0

        Walking distance to 2 Walt Disney World Parks

        Orlando Metropolitan Resort $35
        Orlando Metropolitan Resort

        Orlando Metropolitan Resort

        8444 Austrian Court, Orlando
           
          2.0
          of 5, from 5,573 reviews
          2.5 out of 5.0

          Across the Blvd. to The I Wheel on International Drive. The Metropolitan Resort is walking distance to countless restaurants, pointe Orlando's shops, Orlando Convention Center, SeaWorld, Universal Orlando and many other attractions.

          Mystic Dunes Resort & Golf Club by Diamond Resorts $103
          Mystic Dunes Resort & Golf Club by Diamond Resorts

          Mystic Dunes Resort & Golf Club by Diamond Resorts

          7600 Mystic Dunes Lane, Kissimmee
             
            4.2
            of 5, from 5,653 reviews
            3.5 out of 5.0

            Set on 600 lushly landscaped acres near Celebration, Mystic Dunes Resort & Golf Club by Diamond Resorts is just 2 miles from Walt Disney World Resort and a short drive from Universal Studios Orlando, SeaWorld, and other popular Central Florida attractions.

            Maingate Lakeside Resort $34
            Maingate Lakeside Resort

            Maingate Lakeside Resort

            7769 W Irlo Bronson Memorial Hwy, Kissimmee
               
              3.3
              of 5, from 8,977 reviews
              3.0 out of 5.0

              Sprawling across 24 acres in Kissimmee, this Mediterranean-style hotel is located 2 miles from Walt Disney World Resort, and within 17 miles of SeaWorld and Universal Studios.

              Red Lion Hotel Orlando - Kissimmee Maingate $45
              Red Lion Hotel Orlando - Kissimmee Maingate

              Red Lion Hotel Orlando - Kissimmee Maingate

              7300 W Irlo Bronson Hwy, Kissimmee
                 
                3.9
                of 5, from 3,940 reviews
                3.0 out of 5.0

                Set in the center of Kissimmee, this family-friendly motel is 2.7 mi (4.4 km) from Disney's Animal Kingdom® Theme Park, and within 6 mi (10 km) of Disney's Hollywood Studios® and ESPN Wide World of Sports. Disney's Winter Summerland Miniature Golf Course and Disney's Fantasia Gardens Miniature Golf Course are also within 6 mi (10 km).

                Universal's Cabana Bay Beach Resort $198
                Universal's Cabana Bay Beach Resort

                Universal's Cabana Bay Beach Resort

                6550 Adventure Way, Orlando
                   
                  4.5
                  of 5, from 6,396 reviews
                  3.0 out of 5.0

                  Within walking distance of Universal Orlando™ theme parks and Universal CityWalk™, this hotel offers Early Park Admission* to The Wizarding World of Harry Potter™ and Universal's Volcano Bay™ water theme park 1 hour before the theme parks open with valid theme park admission. Complimentary theme park shuttles are available.