Lake Nona Vacations from $538
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Your Lake Nona Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.
The Latest Lake Nona Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Ramada Plaza Resort & Suites by Wyndham Orlando Intl Drive
International Drive District
Save 100% on your flight
Price was $866, price is now $538 per person
$538
per person
Aug 22 - Aug 27
found 1 day ago
Roundtrip flight included
New York (JFK) to Orlando (MCO)
7.8/10 Good! (505 reviews)
It was okay. They charged me with $250 as security deposit which I didn’t get back yet.
Reviewed on Jun 16, 2026
Florida Hotel & Conference Center in the Florida Mall
Save 100% on your flight
Price was $1,272, price is now $669 per person
$669
per person
Sep 1 - Sep 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
9.2/10 Wonderful! (1,363 reviews)
The staff were all pleasant and friendly! Bed wasvery comfortable. The hotel was very comfortable and love that it was connected to The Florida Mall. It was a great experience for my granddaughter and I.
Reviewed on Jun 8, 2026
WorldQuest Orlando Resort
Save 100% on your flight
Price was $1,142, price is now $691 per person
$691
per person
Jul 20 - Jul 27
found 1 day ago
Roundtrip flight included
New York (NYC) to Orlando (MCO)
8.4/10 Very Good! (4,073 reviews)
We stayed at this resort two weekends in the last 8 weeks. The first time our 3 bedroom was outdated and dryer did not work. This last time great remodeled Disney decor beautiful and well equipped.
Reviewed on May 11, 2026
Margaritaville Cottages Orlando by Vstays with H2O Waterpark
Save 100% on your flight
Price was $1,644, price is now $996 per person
$996
per person
Aug 23 - Aug 28
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
9.2/10 Wonderful! (1,008 reviews)
Loved everything about it.
Reviewed on Jun 8, 2026
Where to stay in Lake Nona
Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
International Drive District
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Hotel Deals
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr Orlando FL
$135 nightly
The price is $152 total per night from Jul 14 to Jul 15
$152 total
Jul 14 - Jul 15
Total with taxes and fees
9.2/10 Wonderful! (5,814 reviews)
"This was a really nice hotel, it’s really nice if your traveling a big group and want to room together and split the price. The villa has everything you could need from silverware to a full kitchen. Only thing is my coffee machine wasn’t working but thats a minor inconvenience. The staff was amazing ..."
Reviewed on Jun 16, 2026
DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd Orlando FL
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Jul 12 to Jul 13
$101 total
Jul 12 - Jul 13
Total with taxes and fees
8.6/10 Excellent! (7,013 reviews)
"Everything was amazing! Thank you!"
Reviewed on Jun 17, 2026
Universal's Cabana Bay Beach Resort
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $169 total per night from Jun 21 to Jun 22
$169 total
Jun 21 - Jun 22
Total with taxes and fees
9/10 Wonderful! (7,076 reviews)
"Nice pool clean toom"
Reviewed on Jun 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Lake Nona attractions
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- Walt Disney World® Resort
- Orlando Vacations
- Nemours Children's Hospital
- Lake Nona Medical City Vacations
- Va Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Visit Lake Nona Medical City
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- David Leadbetter Golf Academy
- Visit Lake Hart
- Lake Hart
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.