1. Hotel Mykonos Panama
- Location: Nuevo Santiago
- Guest rating: 8.8/10 (Excellent, 606 reviews)
- Price: $74 nightly, $82 total, Nov 15 - Nov 16, Total with taxes and fees
- Review: The service is pretty stable., by Yali
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Check prices for these dates, December 12 – 13, 2026
Our top choices for Las Guías hotels
2. Hotel Gran David
- Location: Santiago
- Guest rating: 8.6/10 (Excellent, 451 reviews)
- Price: $88 nightly, $97 total, Nov 13 - Nov 14, Total with taxes and fees
- Review: Great place to stay. I would stay there again., by Roxani
3. HOTEL VISTA LAGO
- Location: La Pena
- Guest rating: 9.4/10 (Exceptional, 128 reviews)
- Price: $70 nightly, $78 total, Nov 18 - Nov 19, Total with taxes and fees
- Review: We went to this hotel for the first time and it’s so amazing, excellent food nothing else to add, by Christian
4. Hotel Plaza Los Tucanes
- Location: Nuevo Santiago
- Guest rating: 8.8/10 (Excellent, 16 reviews)
- Price: $58 nightly, $63 total, Nov 13 - Nov 14, Total with taxes and fees
- Review: Clean room, present staff, and in a central área. Doesn’t have hot water BTW, by Alexandria
5. olivias village room
- Location: Capellania
- Price: $135 nightly, $148 total, Nov 13 - Nov 14, Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare top hotels in Las Guías
Hotel Mykonos PanamaNuevo Santiago View |
Hotel Gran DavidSantiago View |
HOTEL VISTA LAGOLa Pena View |
Hotel Plaza Los TucanesNuevo Santiago View |
|---|---|---|---|
| 8.8Excellent606 reviews | 8.6Excellent451 reviews | 9.4Exceptional128 reviews | 8.8Excellent16 reviews |
| $74 nightly $82 total Nov 15 - Nov 16Total with taxes and fees | $88 nightly $97 total Nov 13 - Nov 14Total with taxes and fees | $70 nightly $78 total Nov 18 - Nov 19Total with taxes and fees | $58 nightly $63 total Nov 13 - Nov 14Total with taxes and fees |
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Top Las Guías Hotel Reviews
Hotel Mykonos Panama
- Address: Panamerican Highway, Nuevo Santiago, Veraguas, 0, PA
- Location: Nuevo Santiago
- Star rating: 3.5/5
- Guest rating: 8.8/10 (606 reviews)
- Review: Great hotel, good food, modern rooms and amenities. The staff was very good and efficient, and it s the best place I've seen outside of the capital city to stay for business, holiday, visit landmarks or spa. Has the largest and best maintain pools and grounds of the non resorts in Panama, by BTraveler, August 7, 2015, rated 10/10 Excellent
HOTEL VISTA LAGO
- Address: Rincón Largo, La Pena, Santiago de Veraguas, 101, PA
- Location: La Pena
- Star rating: 3/5
- Guest rating: 9.4/10 (128 reviews)
- Review: Muy bueno.. solo como feedback un poquito mas de ronda cuando uno esta comiendo y alguien en la piscina por si se quiere pedir algo.. por lo demás todo muy bueno y personas muy amables... volvería!!!!, by Sharyn, November 4, 2026, rated 10/10 Excellent
Hotel Plaza Los Tucanes
- Address: Vía interamericana, Nuevo Santiago, Provincia de Veraguas, PA
- Location: Nuevo Santiago
- Star rating: 3/5
- Guest rating: 8.8/10 (16 reviews)
- Review: 👌, by Franklin, July 12, 2026, rated 10/10 Excellent
Hotel Gran David
- Address: Vía Interamericana, Santiago, Veraguas, PA
- Location: Santiago
- Star rating: 3.5/5
- Guest rating: 8.6/10 (451 reviews)
- Review: Perfect for our stopover from bocas del toro to Panama city, by Agostina, July 14, 2024, rated 10/10 Excellent
Frequently Asked Questions
What is the best area to stay in Las Guías?
The best area to stay in Las Guías is along the main road that connects the town to the coast, offering easy access to both amenities and beach activities.
This central stretch of Las Guías is where you'll find a concentration of guesthouses, local eateries, and small shops. It's a convenient base for exploring the area, with the main road leading directly to the surf breaks and fishing spots.
For couples seeking a relaxed and convenient stay, accommodations in this central area are ideal. You'll be within walking distance of many local dining options and have a straightforward drive to the popular beaches, making it easy to enjoy both the town and the natural surroundings.
Travelers looking for a base to explore the region will also find this area suitable.
When is the best time to go to Las Guías?
The best time to visit Las Guías for pleasant weather and outdoor activities is during the dry season, which runs from mid-December to mid-April.
During these months, you can expect sunny days with minimal rainfall, making it ideal for exploring the natural beauty of the region, including its beaches and protected areas. The temperatures are consistently warm, superb for swimming, snorkeling, and hiking.
Travelers looking for a relaxed beach vacation will find this period particularly appealing. The calm waters and clear skies create excellent conditions for enjoying the coastline and participating in water sports.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Las Guías.
How much is the nightly rate at a Las Guías hotel?
Prices for hotels in Las Guías often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.