Title: Visit Mesa County: 2026 Travel Guide for Mesa County, Colorado | Expedia.com

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# Mesa County, CO

## Colorado

![Pamoramic view of the San Rafael Reef in Emery County in central Utah, part of the Colorado Plateau. ](https://images.trvl-media.com/place/553248635976434253/21f66721-b134-4709-89bb-8bb726f342ad.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Pamoramic view of the San Rafael Reef in Emery County in central Utah, part of the Colorado Plateau. ](https://images.trvl-media.com/place/553248635976434253/21f66721-b134-4709-89bb-8bb726f342ad.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Amazing Place just south of Grand Junction, Colorado.  Primer for Utah](https://images.trvl-media.com/place/1331/22d1dad5-b264-4675-be09-218543787b93.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Natural beauty of the Colorado Plateau](https://images.trvl-media.com/place/1331/d4410be7-f043-43ad-b4e3-cd4273a41ac4.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Liberty Cap , Behind National monument](https://images.trvl-media.com/place/181493/b4497cec-5d22-4f16-a284-f139fc31b798.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

### Popular cities in Mesa County

[Fruita

Known for Biking, Monuments and Mountains

](https://expedia.com/Fruita.dx181493)

Fruita awaits: its museums, monuments, mountain views, and more! 

## Reasons to visit

- Colorado Welcome Center
- Black Ridge Canyons Wilderness
- Rattlesnake Canyon Arches

[Explore City](https://expedia.com/Fruita.dx181493)[Find Hotels](https://expedia.com/Fruita-Hotels.d181493.Travel-Guide-Hotels)

[Grand Junction

Known for Wineries, Monuments and Biking

](https://expedia.com/Grand-Junction.dx1331)

Escape to Grand Junction! Enjoy its wineries, monuments, and natural setting. 

## Reasons to visit

- Canyon View Park

[Explore City](https://expedia.com/Grand-Junction.dx1331)[Find Hotels](https://expedia.com/Grand-Junction-Hotels.d1331.Travel-Guide-Hotels)

[Mesa

Known for Dining, Friendly people and Hunting

](https://expedia.com/Mesa.dx179955)

Like bars and skiing? Get away to quaint Mesa! 

## Reasons to visit

- Powderhorn Resort

[Explore City](https://expedia.com/Mesa.dx179955)[Find Hotels](https://expedia.com/Mesa-Hotels.d179955.Travel-Guide-Hotels)

[Palisade

Known for Wineries, Dining and Friendly people

](https://expedia.com/Palisade.dx143097)

Escape to relaxing Palisade! Enjoy its wineries, food, and hiking. 

[Explore City](https://expedia.com/Palisade.dx143097)[Find Hotels](https://expedia.com/Palisade-Hotels.d143097.Travel-Guide-Hotels)

[Clifton

Known for Friendly people, Dining and Coffee

](https://expedia.com/Clifton.dx180936)

Like dining out? Get away to relaxing Clifton! 

[Explore City](https://expedia.com/Clifton.dx180936)[Find Hotels](https://expedia.com/Clifton-Hotels.d180936.Travel-Guide-Hotels)

[Gateway

Known for Dining, Relaxing and Hiking

](https://expedia.com/Gateway.dx6141167)

Get away to relaxing Gateway! Enjoy the hiking, local cuisine, and museums. 

[Explore City](https://expedia.com/Gateway.dx6141167)[Find Hotels](https://expedia.com/Gateway-Hotels.d6141167.Travel-Guide-Hotels)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

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