Mestre City Center Vacations from $1,408

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Your Mestre City Center Vacation

Leap into your next thrilling adventure with one of our Mestre City Center vacation packages. Spend your days discovering this neighborhood's countless delights, including its bars and pubs. Begin your trip to Mestre City Center by visiting nearby attractions such as San Giuliano Park, Ferretto Square and Porte di Mestre Shopping Center. No matter what your ideal Mestre City Center vacation may look like, you can turn it into reality with Expedia.

The Latest Mestre City Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Ca' Sagredo

Ca' Sagredo

Cannaregio
$1,408
per person
Nov 24 - Nov 29
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Venice (VCE)
9.2/10 Wonderful! (534 reviews)
Old building , very pretty . Good location . Excellent breakfast

Reviewed on Oct 3, 2026

Hotel Nani Mocenigo Palace

Hotel Nani Mocenigo Palace

Dorsoduro
Save 100% on your flight
$2,461
per person
Nov 5 - Nov 11
found 12 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.8/10 Exceptional! (735 reviews)
Our room was lovely. One woman on the staff was extremely helpful. The rest were not helpful at all. During breakfast I almost got myself coffee because the staff was so inattentive. I loved the peaceful location that was still very walkable to all the sites.

Reviewed on Sep 30, 2026

Palazzo Dei Fiori By Room Mate

Palazzo Dei Fiori By Room Mate

Venice City Center
$1,650
per person
Nov 6 - Nov 11
found 7 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
10/10 Exceptional! (95 reviews)
Beautiful apartment in a great location. The hosts were very kind and welcoming. The apartment was extremely clean, comfortable, and beautifully decorated. Everything was thoughtfully designed, and we really enjoyed our stay. Highly recommended!

Reviewed on Oct 4, 2026

Eight Venezia

Eight Venezia

Castello
Save 100% on your flight
$2,239
per person
Nov 5 - Nov 11
found 12 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.8/10 Exceptional! (60 reviews)
Always a great stay and experience. Fabulous staff.

Reviewed on Nov 4, 2024

Orient Express Venezia

Orient Express Venezia

Cannaregio
Save 100% on your flight
$2,876
per person
Nov 5 - Nov 11
found 12 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
No reviews

Where to stay in Mestre City Center

Find the best Mestre City Center areas and neighborhoods for the activities you enjoy most. Learn more about Mestre City Center
A historic building with a dome and bell tower by the water.

Venice City Center

5 out of top 10 points of interest in this area

Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water.

Find hotels in Venice City Center
A canal with gondolas, people walking on the steps, and storefronts with signs like "Giorgio Armani".

San Marco

In the heart of Venice, this densely built area boasts iconic attractions like St Mark's Square, Saint Mark's Basilica, and the Doge's Palace. Find numerous hotels, banks, and high-end shops amid the bustling tourist scene.

Find hotels in San Marco
A canal in Venice with colorful buildings and a bridge.

Cannaregio

Explore historic churches like Santa Maria di Nazareth and Santa Maria dei Miracoli, or admire stunning palazzos such as Ca' d'Oro and Ca' Vendramin Calergi. Enjoy morning markets, local shops, and quaint cafés in this residential, peaceful district.

Find hotels in Cannaregio
A canal with boats docked, historic buildings, and a clear sky.

San Polo

Smallest and most central sestiere, San Polo boasts churches in the west, palaces in the east, and iconic attractions like Rialto Bridge and Scuola Grande di San Rocco.

Find hotels in San Polo
A canal with a bridge, buildings with blue shutters, and a sign in Italian.

Dorsoduro

Boasting the highest land areas in Venice, this sestiere features the stunning Basilica of Santa Maria della Salute and the picturesque Zattere quay. Easily connect to San Marco via Ponte dell'Accademia.

Find hotels in Dorsoduro

Mestre City Center Hotel Deals

Antico Panada

Antico Panada

Calle degli Specchieri 646 Venice VE
Fully refundableReserve now, pay when you stay
$81 nightly
$97 total
Nov 2 - Nov 3
Total with taxes and fees
7/10 Good! (1,172 reviews)
"ideal location close to San Marco. Old style 3-pin power plugs in room do not take 2 pin plug adapters, some light switches were falling off the walls. TV didn't turn on. Internet very intermittent. Included breakfast was very basic. By the third day we went and bought breakfast elsewhere ..."

Reviewed on Oct 5, 2026

Antico Panada
B&B HOTEL Venezia Laguna

B&B HOTEL Venezia Laguna

Isola Nova del Tronchetto 16 Venice VE
Fully refundableReserve now, pay when you stay
$105 nightly
$123 total
Nov 4 - Nov 5
Total with taxes and fees
B&B HOTEL Venezia Laguna
Campanile Venice Mestre

Campanile Venice Mestre

Via Cà Marcello 8G Mestre VE
Fully refundableReserve now, pay when you stay
$68 nightly
$82 total
Nov 4 - Nov 5
Total with taxes and fees
Campanile Venice Mestre
See all 6,132 properties in Mestre City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Mestre City Center attractions

Ferretto Square

8.6/10 (290 reviews)
Take photos of the imposing bell tower in this historic square before dropping in at the upscale boutiques along the colonnade.
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M9 Mestre Museum

8.0/10 (1 review)
You can spend time browsing the exhibits at M9 Mestre Museum during your trip to Mestre. Find some time to visit the casinos or monuments in this walkable area.
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Toniolo Theatre

8.4/10 (7 reviews)
Enjoy a performance at Toniolo Theatre, a storied theater in Mestre. Stroll along the marina or visit the churches in the area.
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Teatro Corso

8.0/10 (1 review)
Get tickets for a show at Teatro Corso, a theater with a story to tell in Mestre. Discover the area's acclaimed art scene and churches.
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Municipal Tower of Mestre

8.6/10 (27 reviews)
You can find out about the history of Mestre when you stop by Municipal Tower of Mestre. Discover the area's acclaimed art scene and churches.
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Duomo di San Lorenzo Martire

Learn about the local history of Mestre when you spend time at Duomo di San Lorenzo Martire. Find some time to visit the casinos or monuments in this walkable area.
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Cinema Teatro Corso

Cinema Teatro Corso is just one of the places to see in Mestre, so why not enjoy the other things to explore during your travels? Find some time to visit the casinos or monuments in this walkable area.
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Things to do

Venice in a Day with St. Mark's Basilica, Doge's Palace, & Gondola Ride

Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour

$187
per adult
94% of travellers recommend
Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour
Sidewalk flanked by colorful buildings in Burano

Murano & Burano Tour

$58
per adult
90% of travellers recommend
Murano & Burano Tour
Taste of Venice: Local Tapas Tastings & Wine Tour

Venice Small Group Food Tour: Venetian Tapas, Wine, Spritz & Gondola Ride

$114
per adult
96% of travellers recommend
Venice Small Group Food Tour: Venetian Tapas, Wine, Spritz & Gondola Ride
See all activities in Venice
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.