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Our top choices for Mission San Diego Station vacation homes

Cozy, Spacious, Family-Friendly + LARGE YARD W/ HOT TUB ~by all attractions!

Cozy, Spacious, Family-Friendly + LARGE YARD W/ HOT TUB ~by all attractions!
Mid-City
10.0 out of 10, Exceptional, (7)
"Great place to stay! Very thoughtful touches like the folder with the restaurant recommendations and free ear plugs (although we didn't need them). Our kids enjoyed the jigsaw puzzle. "
United States
Marilou D.
Cozy, Spacious, Family-Friendly + LARGE YARD W/ HOT TUB ~by all attractions!

Relax & Play: Pool, Golf Simulator, Gym and Powerful AC

Relax & Play: Pool, Golf Simulator, Gym and Powerful AC
Del Cerro
10.0 out of 10, Exceptional, (1)
"We had a great time at this house. The inside was comfortable and spacious, and the outdoor yard was beautiful. The house was clean and located in a nice and quiet neighbourhood."
United States
Anton M.
Relax & Play: Pool, Golf Simulator, Gym and Powerful AC

Large Backyard w/ Firepit and Grill

Large Backyard w/ Firepit and Grill
Allied Gardens
Large Backyard w/ Firepit and Grill

15 Min to Beach and Zoo! | Private Yard w/ Hot Tub

15 Min to Beach and Zoo! | Private Yard w/ Hot Tub
Serra Mesa
15 Min to Beach and Zoo! | Private Yard w/ Hot Tub

Private Hilltop Stay; Sunset Views + Stylish Comfort

Private Hilltop Stay; Sunset Views + Stylish Comfort
2.0 star property
Allied Gardens
7.0 out of 10, Good, (2)
"10/10 I’ll definitely recommend!! "
United States
Mario K.
Private Hilltop Stay; Sunset Views + Stylish Comfort

The San Diego Sunrise Adobe

The San Diego Sunrise Adobe
Serra Mesa
9.8 out of 10, Exceptional, (16)
"This property is very clean, spacious and comfortable, has great views with the wonderful San Diego sunsets, location is great as everything is under 30 min. Drive, neighborhood is nice and family friendly, we enjoyed our stay in this property and will definitely come back again, also communication with the manager was excellent! "
United States
Alma T.
The San Diego Sunrise Adobe

Entire home, Pool, Free Parking, WiFi, Pets are allowed

Entire home, Pool, Free Parking, WiFi, Pets are allowed
Serra Mesa
8.6 out of 10, Excellent, (18)
"Great for family fun. Location nesr beaches, downtown and balboa Park "
United States
Gregory H.
Entire home, Pool, Free Parking, WiFi, Pets are allowed

Carthage Corner Sunny home near eateries and shops with private pool, updated kitchen, patio

Carthage Corner Sunny home near eateries and shops with private pool, updated kitchen, patio
2.0 star property
Allied Gardens
Carthage Corner Sunny home near eateries and shops with private pool, updated kitchen, patio

Entire home, Heated Pool, Free Parking, WiFi, Pets are allowed

Entire home, Heated Pool, Free Parking, WiFi, Pets are allowed
Grantville
8.0 out of 10, Very Good, (5)
"It was a great place to stay — I enjoyed it and would rent again. There are house rules that aren't listed on the app, but they were reasonable and acceptable."
United States
Diamond W.
Entire home, Heated Pool, Free Parking, WiFi, Pets are allowed

Pool, Spa & City Views: Luxe Home in San Diego!

Pool, Spa & City Views: Luxe Home in San Diego!
Del Cerro
9.6 out of 10, Exceptional, (18)
"Definitely a must stay! House was amazing!"
United States
Heather Y.
Pool, Spa & City Views: Luxe Home in San Diego!

Keighley Private Guest House in fabulous San Diego near all attractions!

Keighley Private Guest House in fabulous San Diego near all attractions!
Allied Gardens
8.8 out of 10, Excellent, (5)
"Cozy place to stay! My friend and I really enjoyed ourselves. "
United States
Melanie B.
$130 nightly
The price is $144
Dec 14 - Dec 15
Total with taxes and fees
Keighley Private Guest House in fabulous San Diego near all attractions!

3 bedroom Central Escape - Hot Tub, Fire Pit & newly renovated sunny back yard

3 bedroom Central Escape - Hot Tub, Fire Pit & newly renovated sunny back yard
2.0 star property
Allied Gardens
10.0 out of 10, Exceptional, (9)
"Perfect place for our stay. Easy, prompt and clear communication."
United States
Neil W.
3 bedroom Central Escape - Hot Tub, Fire Pit & newly renovated sunny back yard

3BR 2 bth Snap Dragon Stadium view w/game room & hot tub 15 mins from the beach

3BR 2 bth Snap Dragon Stadium view w/game room & hot tub 15 mins from the beach
Serra Mesa
10.0 out of 10, Exceptional, (2)
"We had a great time at this house. It had all the things we needed to feel right at home. It was very welcoming and provided entertainment for everyone. Thank you!"
United States
Mayra Z.
3BR 2 bth Snap Dragon Stadium view w/game room & hot tub 15 mins from the beach

San Diego Home close to all w/Pool and Hot tub!

San Diego Home close to all w/Pool and Hot tub!
Serra Mesa
10.0 out of 10, Exceptional, (3)
"wonderful stay and great hosts!"
United States
Michelle L.
San Diego Home close to all w/Pool and Hot tub!

Casa Sunset cozy home in central SD, views, fire pit, and games & pet friendly!

Casa Sunset cozy home in central SD, views, fire pit, and games & pet friendly!
Serra Mesa
Casa Sunset cozy home in central SD, views, fire pit, and games & pet friendly!

Effortless SD Getaway - Spacious Yard + Prime Location

Effortless SD Getaway - Spacious Yard + Prime Location
Serra Mesa
6.0 out of 10, (2)
"We had a great experience staying here. Host was quick with communication and even went above and beyond adding a couple accessibility items as I’m in a wheelchair and they wanted to make my stay comfortable. The neighborhood had a lot of cars parked on the streets but seemed quiet overall. "
United States
Josiah S.
Effortless SD Getaway - Spacious Yard + Prime Location

Yellowing House w/Local Artist Murals

Yellowing House w/Local Artist Murals
Allied Gardens
4.0 out of 10, (1)
"The biggest gripe with this place is it shouldn’t be allowed on VRBO at all, since you don’t have the entire property to yourself. Laundry is shared with another tenet occupying the property. This fact was not disclosed until the day before we checked in and left us feeling uncomfortable upon arrival. In the instructions from the host, we were supposed to message them so that they can pick up their Amazon packages, which we didn’t do because it made us feel at risk for our own safety (why not...
United States
Jerod A.
Yellowing House w/Local Artist Murals

Spacious 4BR Retreat with Hot Tub, Fire Pit, Patio

Spacious 4BR Retreat with Hot Tub, Fire Pit, Patio
Mid-City
Spacious 4BR Retreat with Hot Tub, Fire Pit, Patio

Amazing Views & Great Location at Casa Del Cerro, close to SDSU

Amazing Views & Great Location at Casa Del Cerro, close to SDSU
Del Cerro
10.0 out of 10, Exceptional, (6)
"this vacation was about getting some much needed R&R and visiting our daughter who attends SDSU. The house is really only 5 minutes from campus, very well appointed, comfortable and CLEAN! We hope to stay there again! "
United States
Lil B.
Amazing Views & Great Location at Casa Del Cerro, close to SDSU

2000SqFt Oasis Outdoor Patio BBQ for Family 6Beds, 4KTV, 4BedRoom, Fast EV 🔌

2000SqFt Oasis Outdoor Patio BBQ for Family 6Beds, 4KTV, 4BedRoom, Fast EV 🔌
Allied Gardens
10.0 out of 10, Exceptional, (1)
"The house is nicely decorated with nice size bedrooms and a large kitchen. The bathroom is small and the baseboards could have been cleaner but the shower was great with good water pressure. The neighborhood is very nice and quiet. The owner was easy to work with and the check in process was also easy. It just needs an update on linens and towels and maybe a dresser or shelves in the bedrooms. I would stay here again."
United States
Natalie R.
2000SqFt Oasis Outdoor Patio BBQ for Family 6Beds, 4KTV, 4BedRoom, Fast EV 🔌
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission San Diego Station Hotel Reviews

Find out more about Mission San Diego Station

What types of Vacation Homes can I find in Mission San Diego Station?

At Expedia, you’ll find great Mission San Diego Station Vacation Homes for your family vacation, business trip, romantic weekend break, and more. If you’re planning a vacation with kids, try using the traveler experience filter to select “Family-friendly” Mission San Diego Station Vacation Homes. Or, if you’re traveling for work, you can check the “Business-friendly” box to find business-oriented places to stay in Mission San Diego Station. While you’re making your decision, you can use our map facility to view your shortlisted properties and their distance from Mission San Diego Station, or nearby places of interest. There are great places to stay for every budget, so if you need cheap Vacation Homes in Mission San Diego Station, use our simple search function to help you secure a great deal.

How much do Vacation Homes cost in Mission San Diego Station?

The price per night for Mission San Diego Station Vacation Homes in 2026 can start from as low as *. The cost of Vacation Homes varies depending on a number of factors: the dates of your stay, the exact location of the accommodation, and whether there are any special events taking place near Mission San Diego Station, to name just three. When there’s a high demand for rooms in Mission San Diego Station, this can cause prices to increase, whereas traveling during a quieter time of the year can mean lower prices. Booking through Expedia can help you find some of the best deals for cheap Vacation Homes in Mission San Diego Station, so you can sleep easy without going over your budget.

How to find the best deals on Mission San Diego Station Vacation Homes?

Expedia’s search function can help you find some of the best deals on Mission San Diego Station Vacation Homes. You can select a minimum and maximum price per night according to your budget, and filter by guest ratings and star ratings to ensure you find the right Vacation Homes for your needs. Changing the sort order according to price can also help you to view cheap Vacation Homes in Mission San Diego Station at a glance, and you can combine this with our own picks to highlight some of the best available offers. Don’t forget, if you’re an Expedia Rewards member, you can use the “Member Prices” filter to make extra savings on your booking.

Why should I choose Expedia to book Mission San Diego Station Vacation Homes?

Booking with Expedia allows you to browse a wide selection of places to stay in Mission San Diego Station, complete with search filters that make it easy to locate Vacation Homes that best meet your specific requirements. Our clear and easy-to-use search function makes it effortless to compare amenities, prices, property types, neighborhoods, and much more. At Expedia, you can also find flights, car rental, and activities, and you can combine your bookings for greater savings. Plus, Expedia Rewards members accrue points on all eligible purchases. Build your points total to gain discounts on subsequent bookings in the future. Membership is free, so go ahead and join.

What is the cancellation policy on booking Mission San Diego Station Vacation Homes?

At Expedia, we understand that plans change, and the good news is you can cancel many bookings for Mission San Diego Station Vacation Homes with a full refund, depending on the rules and restrictions. For example, some Vacation Homes may not give refunds if you cancel your booking within 24 or 48 hours of your arrival date, and some bookings are non-refundable. Be sure to view the policies provided by the Mission San Diego Station Vacation Homes, and confirm the exact cancellation window on your selected location’s details page. If free cancellation is important to you, you can filter for the “Fully refundable” payment type when you search for your Vacation Homes.

*Prices and availability are subject to change. Additional terms may apply 

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