Mission Valley East Vacations from $333

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Your Mission Valley East Vacation

From its dining to its shopping and cafes, there are tons of convincing reasons to book a vacation package to Mission Valley East. When you're ready to leave the everyday behind, this tourist neighborhood has a spot just for you. Hoping to see the sights during your trip to Mission Valley East? Make sure you check out nearby attractions such as Snapdragon Stadium, Hotel Circle and Fashion Valley Mall. Expedia will help you turn your ideal Mission Valley East vacation into reality, no matter your travel plans or budget.

The Latest Mission Valley East Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

Downtown San Diego
$333
per person
Dec 5 - Dec 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (2,663 reviews)
Bahia Resort Hotel

Bahia Resort Hotel

Central Mission Beach
Save 100% on your flight
$478
per person
Dec 4 - Dec 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (2,417 reviews)
Beautiful resort near the bay

Reviewed on Oct 3, 2026

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Mission Valley
Save 100% on your flight
$479
per person
Dec 4 - Dec 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (3,102 reviews)
Great for comic con goers.

Reviewed on Oct 3, 2026

Hotel Z

Hotel Z

Downtown San Diego
Save 100% on your flight
$343
per person
Dec 5 - Dec 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (1,188 reviews)
We had a great stay at Hotel Z. Lovely place. Friendly staff. Comfortable room. We chose this place for it’s proximity to Petco Park. It’s a short 5-10 minute walk. The hotel is in a vibrant location, the Gaslamp district, with a plethora of dining and drinking options.

Reviewed on Oct 3, 2026

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

Downtown San Diego
Save 100% on your flight
$463
per person
Dec 5 - Dec 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (1,557 reviews)
Room was nice but needs some updating. Pool staff for ordering food was not attentive.

Reviewed on Oct 3, 2026

Where to stay in Mission Valley East

Find the best Mission Valley East areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley East
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

3 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego
A pier extending into calm waters with people on it and a sandy beach with seaweed and a few individuals.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Find hotels in Pacific Beach
A sandy beach with a lifeguard tower, ocean waves, and people in the distance.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Find hotels in Mission Beach
A lively street scene with outdoor seating at various bars and restaurants, including 'The Field' and 'Sloppy Joe's'.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Find hotels in Gaslamp Quarter
An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

1 out of top 10 points of interest in this area

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Find hotels in Mission Bay

Mission Valley East Hotel Deals

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$135 nightly
$156 total
Oct 5 - Oct 6
Total with taxes and fees
DoubleTree by Hilton Hotel San Diego - Mission Valley
Ramada Suites by Wyndham San Diego/Hotel Circle Area

Ramada Suites by Wyndham San Diego/Hotel Circle Area

631 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$72 nightly
$83 total
Oct 5 - Oct 6
Total with taxes and fees
7/10 Good! (1,010 reviews)
"Great place to stay!"

Reviewed on Oct 3, 2026

Ramada Suites by Wyndham San Diego/Hotel Circle Area
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$139 nightly
$159 total
Oct 20 - Oct 21
Total with taxes and fees
Hilton San Diego Mission Valley
See all 8,947 properties in Mission Valley East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Mission Valley East attractions

Snapdragon Stadium

8.4/10 (243 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Mission Valley Mall

8.8/10 (53 reviews)
You can do some window-shopping at Mission Valley Mall during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

SDSU Mission Valley

Explore the campus of SDSU Mission Valley as part of your travels around San Diego. Check out the shops and top-notch restaurants in this family-friendly area.
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Things to do

San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

$71
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

$11
per adult
San Diego: Luggage Storage in Marina
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.