Mission Valley East Vacations from $268

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Your Mission Valley East Vacation

From its dining to its shopping and cafes, there are tons of convincing reasons to book a vacation package to Mission Valley East. When you're ready to leave the everyday behind, this tourist neighborhood has a spot just for you. Hoping to see the sights during your trip to Mission Valley East? Make sure you check out nearby attractions such as Snapdragon Stadium, Hotel Circle and Fashion Valley Mall. Expedia will help you turn your ideal Mission Valley East vacation into reality, no matter your travel plans or budget.

The Latest Mission Valley East Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Price was $536, price is now $268 per person
$268
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.4/10 Very Good! (1,627 reviews)
Clean room and hotel over all. Loved that there is a Starbucks pick up store front right on the bottom floor just adjacent from the lobby.

Reviewed on Nov 27, 2025

La Jolla Beach and Tennis Club

La Jolla Beach and Tennis Club

4 out of 5
La Jolla Shores
Price was $792, price is now $379 per person
$379
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.8/10 Excellent! (485 reviews)
Fabulous place. Marine Room dining exquisite. Breakfast at the restaurant was only a “C”.

Reviewed on Nov 23, 2025

Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
Carmel Valley
Price was $1,311, price is now $632 per person
$632
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.6/10 Exceptional! (909 reviews)
Comfortable accommodations and beautiful accommodations

Reviewed on Oct 25, 2025

Quiet Mind Mountain Lodge, Retreat and Spa

Quiet Mind Mountain Lodge, Retreat and Spa

4.5 out of 5
Price was $633, price is now $317 per person
$317
per person
Jan 22 - Jan 28
found 10 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (558 reviews)
The room has a nice calm and peaceful vibe. Overall, liked the stay.

Reviewed on Nov 25, 2025

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

4 out of 5
Downtown San Diego
Price was $1,125, price is now $571 per person
$571
per person
Feb 4 - Feb 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (547 reviews)
The room was nice and staff were very friendly and helpful. The building itself has good security. My TV remote stopped working and they had it fixed quickly. Laundry was not working. We did not ask to have it fixed because we were fine without it, but I'm sure they would have if we did.

Reviewed on Nov 19, 2025

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Where to stay in Mission Valley East

Find the best Mission Valley East areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley East
US Grant Hotel

Downtown San Diego

3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego

Mission Valley East Hotel Deals

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Dec 7 to Dec 8
$131 total
Dec 7 - Dec 8
Total with taxes and fees
8/10 Very Good! (2,203 reviews)
Room was excellent, clean and friendly staff at all times of the day

Reviewed on Nov 24, 2025

Hilton San Diego Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Dec 21 to Dec 22
$126 total
Dec 21 - Dec 22
Total with taxes and fees
8.2/10 Very Good! (1,359 reviews)
Yes and took had missed a drinking water bottle but other than that all looked well

Reviewed on Nov 24, 2025

DoubleTree by Hilton Hotel San Diego - Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Dec 7 to Dec 8
$136 total
Dec 7 - Dec 8
Total with taxes and fees
8.4/10 Very Good! (1,622 reviews)
Clean room and reasonably priced parking.

Reviewed on Nov 24, 2025

Sheraton Mission Valley San Diego Hotel
See all 8,837 properties in Mission Valley East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Mission Valley East

Finally made it here, too bad they lost...

Snapdragon Stadium

Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Snapdragon Stadium

Mission Valley Mall

You can do some window-shopping at Mission Valley Mall during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Mission Valley Mall

Things to do

San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

$71
per adult
86% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

$55
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
Great Scenery

San Diego Sunset Cruise from Mission Bay

$40
per adult
78% of travellers recommend
San Diego Sunset Cruise from Mission Bay
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.