Top 10 Hotels in Mosopuquio (from $16) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Mosopuquio

Pet friendly

Apartment

Spa

Condo

Hot tub

Pool

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Mosopuquio hotels

A lakeside building with a reflection in the water, surrounded by trees.

A spacious bedroom with a large bed, a wooden ceiling, and a view of the city through a large window.

A resort with a swimming pool, lounge chairs, and a gazebo.

A brick pathway with a wooden railing, surrounded by greenery and trees.

1. Hotel El Lago by Luoxo

Sabandía

Cory

$88 nightly

$88 total

Oct 4 - Oct 5

An indoor dining area with wicker chairs and tables, wooden ceiling beams, and a view of the cityscape through large windows.

An outdoor restaurant with wicker furniture, tables with menus, and a city view at night.

A reception area with a stone counter, two vases with flowers, framed artwork on the wall, and a large text display.

A spa area with a hot tub, a marble table with a vase of flowers, and a view of the city through large windows.

2. Sonesta Hotel Arequipa

Cerro Colorado District

sharon

$116 nightly

$116 total

Sep 4 - Sep 5

An outdoor dining area with tables and chairs, lanterns, and a view of a historic building with two towers and a mountain in the background.

A hotel room with a bed, a stone fireplace, a large window with curtains, and framed pictures on the wall.

A modern spa room with a massage table, wooden paneling, a sink, and a mirror.

A grand hallway with ornate furniture, a chandelier, and a mirror reflecting the room.

3. Katari Hotel At Plaza de Armas

Historical Center

Victoria

$101 nightly

$101 total

Oct 4 - Oct 5

A courtyard with stone flooring, a central door with a decorative arch, and potted plants.

A table with a cup, teapot, plate of fruit, and croissant, overlooking a cityscape.

A bedroom with a brick wall, a bed with a metal headboard, a chandelier, and a mirror.

A stone staircase leading to a small waterfall, surrounded by greenery and a rustic stone wall.

4. Acolpacha - Tambo Boutique

Historical Center

Leomar

$82 nightly

$82 total

Oct 3 - Oct 4

A stone arched window with a cushioned bench and two pillows, overlooking a garden with plants and a door.

An interior corridor with a rustic stone wall, a wooden door, and a welcome sign.

An arched stone structure with potted plants and a metal door.

5. Hampton by Hilton Arequipa

Historical Center

Kenneth

$113 nightly

$113 total

Sep 11 - Sep 12

A restaurant with a tiled backsplash, wooden chairs, and a counter with a mirror and plants.

A hotel room with a bed, a desk with a chair, a TV mounted on the wall, and a window with curtains.

A living room with a brown leather sofa, two blue armchairs, a round coffee table, and three wall-mounted mirrors.

A hotel room with a wooden headboard, a bed with white and blue bedding, a bedside table with a lamp, a chair, and a large window with curtains.

6. Hostal Lirium

Sachaca

Alexander

$24 nightly

$24 total

Sep 11 - Sep 12

A pathway leading through a garden with a stone border, surrounded by greenery and potted plants.

Villa Elisa Hotel Boutique with a white facade, blue shutters, and a tiled roof.

A stone staircase leading to a glass bridge, surrounded by lush greenery and flowering plants.

A swimming pool with a person in the water, surrounded by greenery and buildings.

7. Hotel Boutique Villa Elisa

Historical Center

federico

$72 nightly

$72 total

Sep 5 - Sep 6

A hotel room with a bed, a small table with chairs, a window with curtains, and a nightstand with a lamp and a book.

A breakfast table set with various food items, cups, and a thermos.

A nighttime fountain with water jets in a courtyard, surrounded by palm trees and a building with arches.

A hotel room with two beds, a desk with a laptop, and a chair.

8. HOTEL FLORENTINO

José Luis Bustamante y Rivero

$86 nightly

$86 total

Sep 4 - Sep 5

A covered patio area with a glass table and chairs, surrounded by arches and potted plants.

A dining area with a table set for a meal, a chandelier, and a window with decorative iron bars.

A building with a sign reading "CASA CAMPO Suites & Convivencias."

A well-maintained garden with a variety of trees, a lawn, and a white metal fence.

9. Hotel Casa Campo by Cassana

Cayma

Jose

$47 nightly

$47 total

Sep 4 - Sep 5

A picnic setup with food and drinks on a wooden table in a grassy area with a tree and a llama in the background.

A swimming pool with a clear blue water, surrounded by a building with a pink facade, and a tree in the foreground.

A hotel entrance with a sign reading "Costa del Sol Wyndham".

A spacious lobby with two sofas facing a fireplace, surrounded by tables and chairs, and a large mural on the walls.

10. Wyndham Costa del Sol Arequipa

Historical Center

Pierre

$153 nightly

$153 total

Sep 27 - Sep 28

A spacious hotel room with a large bed, a marble-patterned headboard, a bedside table with a lamp, and a view of the city through large windows.

A living room with a sofa, a lamp, and a small table with a plant.

A rooftop terrace with a view of a cityscape and mountains in the distance.

11. ANDARI HOTELES

Historical Center

Kelly

$64 nightly

$64 total

Sep 4 - Sep 5

A bedroom with a four-poster bed, a bedside table, a bench, a nightstand, and a mirror.

A hallway with a wooden door, a lamp, a sofa, and a stone wall.

A spacious indoor courtyard with wicker furniture, potted plants, and a large open area.

A bar area with a counter, stools, and a television screen.

12. Casa Andina Premium Arequipa

Historical Center

Genoveva

$155 nightly

$155 total

Sep 25 - Sep 26

A hotel lobby with a reception desk, a seating area, and a refrigerator.

A breakfast buffet with various fruits, beverages, and a sign indicating self-service.

A breakfast table with various food items and drinks, a rose, and a view of a cityscape with buildings and a mosque.

13. Hotel TerraMistica Monasterio

José Luis Bustamante y Rivero

Carlos

$40 nightly

$40 total

Sep 7 - Sep 8

A hotel room with a bed, bedside table, lamp, and a small table with a vase of sunflowers.

A chef preparing food at a wooden table with a rustic wall in the background.

A wicker sofa with cushions, a small table with a teapot and candles, and a view of two lit towers against a mountain backdrop.

A hallway with a wall displaying various decorative items and a website address.

14. Los Tambos - Boutique

Historical Center

mark

$69 nightly

$69 total

Oct 2 - Oct 3

A modern living room with a flat-screen TV, a sofa, a coffee table, and a built-in aquarium.

A narrow street with a white building featuring a wooden door and a window with iron bars.

A reception desk with a sign that reads "La Casa de Fuma". There is a vintage telephone and a printer on the desk.

A variety of potted plants arranged on a ledge against a wall.

15. Hotel La Casa de Irma Arequipa

Historical Center

May

$34 nightly

$34 total

Sep 5 - Sep 6

A modern building with glass facades and a reflective pool.

A modern hotel room with a large bed, bedside lamps, a bathroom with a bathtub, and a shower.

A large bathtub with a wooden bench, a towel rack, and a small plant.

A balcony with a table featuring a bottle and two glasses, overlooking a historic building with two towers and a mountain backdrop.

16. ARIQUEPAY HOTEL

Historical Center

Robert

$129 nightly

$129 total

Sep 22 - Sep 23

A table with a glass of red wine, a glass of white wine, and a glass of dark beverage, along with a plate of food and a bowl of fruit, set against a scenic view of a city and a sunset.

A modern hotel lobby with a reception desk, seating area, and artwork on the walls.

A buffet with various food items including yogurt, juice, water, cheese, ham, and bread.

A rooftop pool area with a view of a cityscape, including a prominent tree and distant buildings.

17. Vita Hoteles Arequipa

Historical Center

Amey

$74 nightly

$74 total

Sep 4 - Sep 5

A pool area with a stone ceiling, a chandelier, and potted plants.

An arched entrance with a brick ceiling, potted plants, and a pathway leading to a building.

A courtyard with potted plants, a fountain, and a building with yellow walls and arches.

A lobby with a high arched ceiling, a reception desk, and a seating area with a chandelier.

18. La Hostería

Historical Center

Rommy

$100 nightly

$100 total

Oct 4 - Oct 5

An outdoor patio with tables and chairs, a drink on one table, and string lights.

A room with a wooden door, a bed with a rolled towel, and a view of a yellow building with a balcony.

A hotel room with a bed, a desk, a chair, a TV, and a balcony with a view of buildings.

A staircase with potted plants, a wooden ceiling, and a white wall with hanging planters.

19. Le Foyer Arequipa

Historical Center

Jennifer

$25 nightly

$25 total

Sep 18 - Sep 19

A courtyard with stone walls, a wooden door, wicker furniture, and potted plants.

A bedroom with a large bed, wooden furniture, a chandelier, and a stone wall.

A breakfast buffet with various food items and beverages.

A spacious living area with a wooden floor, a fireplace, a dining table, and a staircase with a wrought iron railing.

20. Hotel Casona Solar

Historical Center

Priscilla

$95 nightly

$95 total

Sep 4 - Sep 5

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Mosopuquio Hotel Reviews

Casa Andina Select Arequipa Plaza

10/10 Excellent

"The staff in Arequipa was extremely helpful. Roberto (I do apologize to Robert, I lost the card he gave me with all the staff members to I can add their names) and his staff members were amazing. They help us navigate the taxis, make sure our transportation was ready for us. Helped us with our luggage. I love how friendly and easy it was to talked to all of them from the receptionists, the house maids, the restaurant waiters, all of them friendly and professionals. I was impress that every guess was treated with respect. A highly recommended stay. I want to say thank you for a wonderful stay. Will definitely book again next time we are in Peru."

Casa Andina Premium Arequipa

10/10 Excellent

"Good location for walking all around. Helpful staff and clean room."

Katari Hotel At Plaza de Armas

10/10 Excellent

"Great location in Pa"

Acolpacha - Tambo Boutique

10/10 Excellent

"Chambre propre. Employé poli est très serviable. Ont garder nos gros bagage pendant notre trek."

Wyndham Costa del Sol Arequipa

10/10 Excellent

"Great location!"

Los Tambos - Colonial

10/10 Excellent

"Fantastic location. Really attentive and helpful staff. Lovely rooms."

Hampton by Hilton Arequipa

10/10 Excellent

"Beautiful property, fits perfectly with the Arequipa vibe"

Los Tambos - Boutique

10/10 Excellent

"We’ve been hotel hopping all over South America and this hotels is easily one of the best we’ve stayed at. The breakfast was made to order and amazing. The staff are great and the location works well."

Hotel Boutique Villa Elisa

10/10 Excellent

"Nice place to stay just outside the center"

More cheap stays in Mosopuquio

Gran Hotel

Calle Alvares Thomas 451 Arequipa Arequipa

$16 nightly

$16 total

Sep 17 - Sep 18

8/10 Very Good! (26 reviews)

HOTEL INKALMA SANTA MARTA

Calle Santa Marta 208 B Arequipa Arequipa

$33 nightly

$33 total

Sep 28 - Sep 29

9.2/10 Wonderful! (16 reviews)

La Casa de Margott

Jerusalen Street #304 Cercado Arequipa

$40 nightly

$40 total

Sep 5 - Sep 6

Hostal La Casa de Melgar

Calle Melgar Nro. 108 - Cercado Arequipa Arequipa

$60 nightly

$60 total

Sep 6 - Sep 7

9/10 Wonderful! (68 reviews)

Viajero Arequipa Hostel

317 C. Jerusalén Arequipa Arequipa

Get rates

9.2/10 Wonderful! (17 reviews)

El Caminante Class

207 - A Santa Catalina Arequipa Arequipa

Get rates

Frequently asked questions

What is the best area to stay in Mosopuquio?

The best area to stay in Mosopuquio is the central district surrounding the Plaza de Armas, which is the heart of the town.This area is the main hub for visitors, characterized by its well-preserved historic architecture and a relaxed pace. The Plaza de Armas itself is a central green space, often bustling with local activity, and is surrounded by important buildings like the local church and municipal offices. It's an excellent base for exploring the town on foot.For couples, this central district offers a pleasant and romantic setting. You'll find a selection of guesthouses and small hotels within easy walking distance of local eateries and craft shops. The evening strolls around the plaza provide a nice opportunity to experience the town's quiet charm.Solo travelers will also find the area around the Plaza de Armas to be very convenient.

When is the best time to go to Mosopuquio?

The best time to visit Mosopuquio is during the dry season, which runs from April to November.During these months, you'll experience clear skies and plenty of sunshine, making it ideal for exploring the natural beauty of the Arequipa Region. The weather is generally mild during the day, with cooler evenings, so packing layers is advisable. This period is superb for outdoor activities like hiking and visiting local attractions without the interruption of rain.For travelers looking to explore the natural landscapes, especially those interested in hiking or photography, the dry season offers the most favorable conditions.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mosopuquio.

How much is the nightly rate at a Mosopuquio hotel?

Prices for hotels in Mosopuquio often vary, but you can find a great deal from $16 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Arequipa Vacation Rentals

Things to do in Arequipa

Find hotels in Mosopuquio from $16

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Mosopuquio

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mosopuquio hotels

1. Hotel El Lago by Luoxo

2. Sonesta Hotel Arequipa

3. Katari Hotel At Plaza de Armas

4. Acolpacha - Tambo Boutique

5. Hampton by Hilton Arequipa

6. Hostal Lirium

7. Hotel Boutique Villa Elisa

8. HOTEL FLORENTINO

9. Hotel Casa Campo by Cassana

10. Wyndham Costa del Sol Arequipa

11. ANDARI HOTELES

12. Casa Andina Premium Arequipa

13. Hotel TerraMistica Monasterio

14. Los Tambos - Boutique

15. Hotel La Casa de Irma Arequipa

16. ARIQUEPAY HOTEL

17. Vita Hoteles Arequipa

18. La Hostería

19. Le Foyer Arequipa

20. Hotel Casona Solar

Top Mosopuquio Hotel Reviews

Casa Andina Select Arequipa Plaza

Casa Andina Premium Arequipa

Katari Hotel At Plaza de Armas

Acolpacha - Tambo Boutique

Wyndham Costa del Sol Arequipa

Los Tambos - Colonial

Hampton by Hilton Arequipa

Los Tambos - Boutique

Hotel Boutique Villa Elisa

More cheap stays in Mosopuquio

Gran Hotel

HOTEL INKALMA SANTA MARTA

La Casa de Margott

Hostal La Casa de Melgar

Viajero Arequipa Hostel

El Caminante Class

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app