Title: Mytilene Vacation Rentals from $68: Search Short-Term Rentals | Expedia.com

[Mytilene Travel Guide](https://expedia.com/Mytilene.dx6062865)[Hotels in Mytilene](https://expedia.com/Mytilene-Hotels.d6062865.Travel-Guide-Hotels)[Flights to Mytilene](https://expedia.com/Cheap-Flights-To-Mytilene.d6062865.Travel-Guide-Flights)[Car Rentals in Mytilene](https://expedia.com/Car-Rentals-In-Mytilene.d6062865.Car-Rental-Guide)[Mytilene Vacation Packages](https://expedia.com/Mytilene.d6062865.Destination-Travel-Guides)

![Lesvos (lesbos) island . Greece. Beautiful old town Molyvos (Mithymna) with castle over the rock and  beach](https://images.trvl-media.com/place/6062865/1aa72491-3521-42d6-9b59-0b2ad0423bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6062865/1aa72491-3521-42d6-9b59-0b2ad0423bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6062865&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=6062865&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=6062865&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 17 - Jul 19](https://www.expedia.com/Hotel-Search?regionId=6062865&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mytilene vacation rentals

![In-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/120000000/119900000/119892200/119892175/bb2ad51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Interior](https://images.trvl-media.com/lodging/120000000/119900000/119892200/119892175/c259c889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | In-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/120000000/119900000/119892200/119892175/6ac4a487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119900000/119892200/119892175/aeaf5433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Akti Vigla Premium

[](https://www.expedia.com/Lesvos-Hotels-Akti-Vigla-Premium.h119892175.Hotel-Information)

Lesvos

10/10

Exceptional

(2 reviews)

"Temiz ve nezih konaklama oldu. Memnun kaldım "

![Turkey](https://a.travel-assets.com/egds/marks/flags/tr.svg)

Ahmet

$60 nightly

$68 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Akti-Vigla-Premium.h119892175.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/w2050h1353x99y75-cfa3e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/5445108d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/w1586h1275x337y103-bb2eb2c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/w1991h1535x0y0-3088b018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Loriet

[](https://www.expedia.com/Lesvos-Hotels-Loriet-Hotel.h11098314.Hotel-Information)

Lesvos

8.4/10

Very Good

(80 reviews)

"Nice place, good breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emre

$63 nightly

$73 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Loriet-Hotel.h11098314.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/60000000/60000000/59992500/59992468/c24fe610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/60000000/60000000/59992500/59992468/6e516ec1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/60000000/60000000/59992500/59992468/39a06cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/60000000/60000000/59992500/59992468/c18e4046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa SIGRI

[](https://www.expedia.com/Lesvos-Hotels-Villa-SIGRI.h59992468.Hotel-Information)

MYTILENE

$172 nightly

$172 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Villa-SIGRI.h59992468.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60180000/60177100/60177007/e913aa2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/61000000/60180000/60177100/60177007/2f1c10a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/61000000/60180000/60177100/60177007/2d5acf4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/61000000/60180000/60177100/60177007/722e031c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa PETRA

[](https://www.expedia.com/Lesvos-Hotels-Villa-PETRA.h60177007.Hotel-Information)

ΜΥΤΙΛΗΝΗ

$172 nightly

$172 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Villa-PETRA.h60177007.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/40000000/39190000/39183100/39183042/1f9e9143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/40000000/39190000/39183100/39183042/3a164bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/40000000/39190000/39183100/39183042/a391288c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, espresso maker](https://images.trvl-media.com/lodging/40000000/39190000/39183100/39183042/b12b67e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elies Residences

[](https://www.expedia.com/Lesvos-Hotels-Elies-Residences.h39183042.Hotel-Information)

Lesvos

10/10

Exceptional

(33 reviews)

"Beautiful quiet nice little place.Very cosy !!"

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Sophia

[](https://www.expedia.com/Lesvos-Hotels-Elies-Residences.h39183042.Hotel-Information)

![1 bedroom, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/95000000/94330000/94321900/94321802/2378cc4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/95000000/94330000/94321900/94321802/e18a7de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/95000000/94330000/94321900/94321802/a9eb3c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94330000/94321900/94321802/02c3b872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Modern Studio for Two Mytilene Lesvos

[](https://www.expedia.com/Lesvos-Hotels-Studio-In-The-Center-Of-Mytilini.h94321802.Hotel-Information)

Mytilene

8.0/10

Very Good

(1 review)

"Wir wurden direkt von Stavros herzlich begrüßt. Die Unterkunft ist wie auf den Fotos original. Sehr sauber modern eingerichtet, zentral gelegen. Bei Fragen und auch beim Check out mit unserem Gepäck war Stavros sehr hilfreich . Wir werden die Unterkunft auf jeden Fall weiter empfehlen. Vielen Dank"

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Oya S.

$92 nightly

$97 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Studio-In-The-Center-Of-Mytilini.h94321802.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60180000/60177000/60176944/a6cf846d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/61000000/60180000/60177000/60176944/fd6e5b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/61000000/60180000/60177000/60176944/eecd3c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/61000000/60180000/60177000/60176944/b4929a92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa SYKAMIA

[](https://www.expedia.com/Lesvos-Hotels-Villa-SYKAMIA.h60176944.Hotel-Information)

ΜΥΤΙΛΗΝΗ

$172 nightly

$172 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Villa-SYKAMIA.h60176944.Hotel-Information)

![1 bedroom, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/122000000/121140000/121132700/121132635/bf07d16c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/122000000/121140000/121132700/121132635/16404853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/122000000/121140000/121132700/121132635/w1500h1848x0y0-f80f0511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels](https://images.trvl-media.com/lodging/122000000/121140000/121132700/121132635/w1500h1856x0y0-3b4226ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Your refuge overlooking port

[](https://www.expedia.com/Lesvos-Hotels-Your-Refuge-Overlooking-Port.h121132635.Hotel-Information)

Mytilene

$84 nightly

$84 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Your-Refuge-Overlooking-Port.h121132635.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60010000/60005900/60005815/82d1d188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/61000000/60010000/60005900/60005815/6f9bc941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/61000000/60010000/60005900/60005815/f8591499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/61000000/60010000/60005900/60005815/e42de852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa MOLYVOS

[](https://www.expedia.com/Lesvos-Hotels-Villa-MOLYVOS.h60005815.Hotel-Information)

ΜΥΤΙΛΗΝΗ

$283 nightly

$283 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Villa-MOLYVOS.h60005815.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/60000000/59870000/59860800/59860724/afb0d502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/60000000/59870000/59860800/59860724/a42ddda0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/60000000/59870000/59860800/59860724/b6dbcea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59870000/59860800/59860724/3bf2b685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa ERESOS

[](https://www.expedia.com/Lesvos-Hotels-Villa-ERESOS.h59860724.Hotel-Information)

ΜΥΤΙΛΗΝΗ

$172 nightly

$172 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Villa-ERESOS.h59860724.Hotel-Information)

![1 bedroom, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/91000000/90350000/90345600/90345573/33443c87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/91000000/90350000/90345600/90345573/5d55dc1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry](https://images.trvl-media.com/lodging/91000000/90350000/90345600/90345573/f533c8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/91000000/90350000/90345600/90345573/cb06b1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Experience Comfort in our Newly Remodeled 5A 

[](https://www.expedia.com/Lesvos-Hotels-Experience-Comfort-In-Our-Newly-Remodeled-5A.h90345573.Hotel-Information)

Mitilini

2.0/10

(1 review)

$85 nightly

$90 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Experience-Comfort-In-Our-Newly-Remodeled-5A.h90345573.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/114000000/113200000/113191900/113191843/10d86a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/114000000/113200000/113191900/113191843/b6d84bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/114000000/113200000/113191900/113191843/50231ceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/114000000/113200000/113191900/113191843/60d6ad22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gianni's House

[](https://www.expedia.com/Lesvos-Hotels-Vrbo-Property.h113191843.Hotel-Information)

Polichnitos

$90 nightly

$102 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Vrbo-Property.h113191843.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/71000000/70090000/70084700/70084644/6f406be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa | Dining room](https://images.trvl-media.com/lodging/71000000/70090000/70084700/70084644/5de1aeb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach nearby, 3 beach bars](https://images.trvl-media.com/lodging/71000000/70090000/70084700/70084644/eb206861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa | Living area | 40-inch Smart TV with satellite channels, TV](https://images.trvl-media.com/lodging/71000000/70090000/70084700/70084644/74f4ae21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ouzo Stone House 1, with private pool

[](https://www.expedia.com/Lesvos-Hotels-Ouzo-Stone-Villa-1.h70084644.Hotel-Information)

Lesvos

$251 nightly

$279 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Ouzo-Stone-Villa-1.h70084644.Hotel-Information)

![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/72000000/71080000/71075700/71075644/839d2f00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Living area | 32-inch Smart TV with satellite channels, TV](https://images.trvl-media.com/lodging/72000000/71080000/71075700/71075644/884903f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | 3 bedrooms, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/72000000/71080000/71075700/71075644/18aee99f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach nearby, 3 beach bars](https://images.trvl-media.com/lodging/72000000/71080000/71075700/71075644/fcf3ef4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ouzo Stone House 2, with private pool

[](https://www.expedia.com/Lesvos-Hotels-Ouzo-Stone-Villa-2.h71075644.Hotel-Information)

Lesvos

10/10

Exceptional

(1 review)

$251 nightly

$279 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Lesvos-Hotels-Ouzo-Stone-Villa-2.h71075644.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

Villas

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Aparthotels

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Private vacation homes

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## Top Mytilene Hotel Reviews

![The Loriet](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/w2050h1353x99y75-cfa3e46c_y.jpg)

### The Loriet

10/10 Excellent

"Lovely mansion house and a great breakfast."

[](https://expedia.com/Lesvos-Hotels-Loriet-Hotel.h11098314.Hotel-Information)

![Theofilos Paradise Boutique Hotel](https://images.trvl-media.com/lodging/13000000/12320000/12319300/12319222/a275125a_y.jpg)

### Theofilos Paradise Boutique Hotel

10/10 Excellent

"The room was impeccable. The staff were courteous enough to let us check in a few hours early after a long trip. "

[](https://expedia.com/Lesvos-Hotels-Theofilos-Paradise-Boutique-Hotel.h12319222.Hotel-Information)

![Hotel Lesvion](https://images.trvl-media.com/lodging/21000000/20170000/20161500/20161415/43b6e37b_y.jpg)

### Hotel Lesvion

10/10 Excellent

"First of all, all the hotel staff were extremely friendly, kind, and helpful. We thank them all individually. The hotel's location, cleanliness, and the variety and quality of the breakfasts were excellent. We are eagerly looking forward to staying at this hotel again. Thank you very much."

[](https://expedia.com/Lesvos-Hotels-Hotel-Lesvion.h20161415.Hotel-Information)

![Agora Apartments](https://images.trvl-media.com/lodging/107000000/106750000/106742200/106742165/9f32ed12_y.jpg)

### Agora Apartments

10/10 Excellent

"Great facility, but do not use your car to reach the property. No close by parking, narrow streets. Great communication friendly staff. "

[](https://expedia.com/Lesvos-Hotels-Agora-Apartments.h106742165.Hotel-Information)

![Lasia Hotel](https://images.trvl-media.com/lodging/30000000/29860000/29858900/29858872/39643eb9_y.jpg)

### Lasia Hotel

10/10 Excellent

"Very friendly stuff. Helpful and nice Close to public transport and a cross from a very nice beach"

[](https://expedia.com/Lesvos-Hotels-Lasia-Hotel.h29858872.Hotel-Information)

![Oikies Small Elegant Houses](https://images.trvl-media.com/lodging/4000000/3580000/3576000/3575954/fa614f01_y.jpg)

### Oikies Small Elegant Houses

10/10 Excellent

"Great place! Don’t look for anywhere else!"

[](https://expedia.com/Lesvos-Hotels-Oikies-Small-Elegant-Houses.h3575954.Hotel-Information)

![Elies Residences](https://images.trvl-media.com/lodging/40000000/39190000/39183100/39183042/1f9e9143_y.jpg)

### Elies Residences

10/10 Excellent

"The sea view pool and the landscaping were so impressive and tranquil. Wish we could have stayed longer. The Molivos apartment was very nice and relaxing with 2 bedrooms , 2 bathrooms, 2 verandas, kitchen. LR, communal pool, 2 extra sunbeds on the grass under a tree, and parking. Perfect apartment for a family or friends. We are going again in July with our 21 and 23 year old children to have quality time. Marina and the staff were very friendly. There’s a little bar near the pool for drinks and toast which is convenient. "

[](https://expedia.com/Lesvos-Hotels-Elies-Residences.h39183042.Hotel-Information)

## Find out more about Mytilene

**Everything you need to know about Mytilene vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mytilene vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mytilene vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Mytilene vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Mytilene. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mytilene in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $68 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Mytilene rentals**

At Expedia, we put the best Mytilene vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mytilene rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mytilene vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mytilene. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Villas in Mytilene ](https://expedia.com/Mytilene-Villas.d6062865-aaVillas.Travel-Guide-Accommodation)
- [Apartments in Mytilene ](https://expedia.com/Mytilene-Apartments.d6062865-aaApartments.Travel-Guide-Accommodation)
- [Vacation Homes in Mytilene ](https://expedia.com/Mytilene-Private-Vacation-Homes.d6062865-aaPrivateVacationHomes.Travel-Guide-Accommodation)

## Frequently asked questions

### Are there vacation rentals in Mytilene?

### What's the top vacation rental that Mytilene has to offer?

### How many vacation rentals will I find in Mytilene?

### What’s there to see and do in Mytilene?

### What’s a vacation rental in Mytilene like?

### Expedia's Latest Trends

Hotels

- [Hotels with Restaurants in Anaxos](https://expedia.com/Anaxos-Hotels-Hotels-With-Restaurants.0-0-d6204806-tHotelswithRestaurants.Travel-Guide-Filter-Hotels)
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Flights

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- [Kapi Flights](https://expedia.com/lp/flights/3000739629/flights-from-kapi)
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Cars

- [Car rentals in Petra](https://expedia.com/Car-Rentals-In-Petra.d181072.Car-Rental-Guide)
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Activities

- [Things to do in Samos Town](https://expedia.com/Things-To-Do-In-Samos-Town.d6062919.Travel-Guide-Activities)

Packages

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General

- [Visit Skála Eresoú](https://expedia.com/Skala-Eresou.dx3000030241)
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- [Visit Vatera](https://expedia.com/Vatera.dx6052053)
- [Visit Vatoussa](https://expedia.com/Vatoussa.dx3000739646)
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- [Visit Anaxos](https://expedia.com/Anaxos.dx6204806)
- [Visit Perama](https://expedia.com/Perama.dx6135648)
- [Visit Skala Mistegnon](https://expedia.com/Skala-Mistegnon.dx6322119)
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- [Visit Skala Neon Kidonion](https://expedia.com/Skala-Neon-Kidonion.dx6355368)
- [Visit Melinta](https://expedia.com/Melinta.dx3000739634)
- [Visit Tsonia](https://expedia.com/Tsonia.dx3000739643)

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