A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Find 5 Star Hotels in Mytilene from $96

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Tonight
Sep 21 - Sep 22
Tomorrow
Sep 22 - Sep 23
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Mytilene 5-star hotels

Exterior
Grand Suite | Minibar, in-room safe, desk, laptop workspace
Deluxe Suite | Terrace/patio
Reception

1. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
United States
Jack
$100 nightly
$130 total
Oct 18 - Oct 19
Total with taxes and fees
Mythical Coast Wellness Retreat
Terrace/patio
2 bars/lounges
Front of property
Terrace/patio

2. Elysion Hotel

Elysion Hotel
Lesvos
Turkey
ANINDYA
$148 nightly
$179 total
Oct 16 - Oct 17
Total with taxes and fees
Elysion Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mytilene.
Heliotrope Hotels

Heliotrope Hotels

Varia Lesvos Lesvos Island
$77 nightly
$96 total
Oct 6 - Oct 7
Total with taxes and fees
Heliotrope Hotels
Loriet Hotel

Loriet Hotel

Vareia, Mitilene Lesvos Lesvos Island
$86 nightly
$106 total
Oct 22 - Oct 23
Total with taxes and fees
8.4/10 Very Good! (91 reviews)
Loriet Hotel
Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

7, Skra str, Hatzidimitriou Park Lesvos
$122 nightly
$145 total
Oct 22 - Oct 23
Total with taxes and fees
9.6/10 Exceptional! (172 reviews)
Theofilos Paradise Boutique Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mytilene

The harbor city's neoclassical mansions and Byzantine castle offer glimpses into its rich past as a trading center. Explore the Archaeological Museum's ancient artifacts, then enjoy fresh seafood at tavernas along the waterfront promenade.

See all hotels in Mytilene
A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

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Find out more about Mytilene

Mytilene Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in Mytilene are your dreams come true. From sprawling resorts to fancy hot spots, theseMytilene 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Mytilene, Lesvos, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Mytilene five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Mytilene 5 star hotels.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Mytilene?
You can find a range of pricing options for 5-star hotels in Mytilene on Expedia. How much you'll pay will depend on when you plan to travel, length of stay and other factors. Compare all of the available properties for your preferred dates and use our pricing and other filters to lock in the ideal high-end stay.
  • Search for the lowest price per night from $96
What makes a hotel 5 stars in Mytilene?
From high-end dining venues and fitness centers to pools and dreamy bedding, the 5-star experience in Mytilene is all about comfort and indulgence. But it calls for more than just top-notch amenities to receive a 5-star rating. Stays must also deliver remarkable guest-focused services like massage treatments, laundry and dry cleaning and room service any time night or day.
Are there any 5-star all-inclusive resorts in Mytilene?
Our handy filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to show the most luxurious hotels in Mytilene where your lodging, meals, entertainment and activities are included in the price. At these stays, your trip is pure leisure from the moment you check in.

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