
New Madrid County Vacations & Trips
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Your New Madrid County Vacation
With a New Madrid County vacation package, you can forget about planning hassles and focus on experiencing all this wonderful destination has on offer. During your trip to New Madrid County, you'll want to tick off a few of its most famous cities. What can't you miss? Portageville. Stop dreaming and start packing, because your New Madrid County vacation is only a few clicks away with Expedia.
Top destinations in New Madrid County

Sikeston

New Madrid
Find the Best New Madrid County Vacation Packages
New Madrid County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
Population | 3,000 |
New Madrid County Hotel Deals

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from Jun 14 to Jun 15
$120 total
Jun 14 - Jun 15
Total with taxes and fees
9/10 Wonderful! (572 reviews)
"The doughnuts and fry potatoes for breakfast were delicious"
Reviewed on Jun 2, 2026

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $125 total per night from Jun 11 to Jun 12
$125 total
Jun 11 - Jun 12
Total with taxes and fees
9.4/10 Exceptional! (84 reviews)
"Great stay, kind staff, very clean property."
Reviewed on May 30, 2026

New Orleans Inn Portageville
600 US-61 Portageville MO
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $57 total per night from Jun 7 to Jun 8
$57 total
Jun 7 - Jun 8
Total with taxes and fees
8/10 Very Good! (767 reviews)
"Great stay with Great people, very clean and welcoming"
Reviewed on Jun 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



















