
North Clayton Vacations from $443
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Your North Clayton Vacation
Discover all the amazing things this neighborhood has to offer with a tailor-made North Clayton vacation package. However you imagine yourself spending your time here, you'll find endless opportunities for relaxation, fun and adventure. Wondering what to see and do during your trip to North Clayton? Nearby attractions like St. Louis Zoo, St. Louis Art Museum and Washington University in St. Louis are good places to begin. Expedia will help turn your ideal North Clayton vacation into reality, whatever your travel plans or budget.
The Latest North Clayton Vacation Packages

Hilton Garden Inn Chesterfield
Reviewed on Oct 26, 2025

The Wildwood Hotel
Reviewed on Dec 12, 2025


Hotel Saint Louis, Autograph Collection
Reviewed on Nov 25, 2025

Crowne Plaza St. Louis Airport by IHG
Reviewed on Nov 27, 2025
Where to stay in North Clayton

Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
North Clayton Hotel Deals

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Clean, nice staff, hot breakfast with variety of options
Reviewed on Dec 8, 2025

Hyatt Regency St. Louis at The Arch
Great stay
Reviewed on Dec 10, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Staff was fantastic and goes above and beyond
Reviewed on Dec 12, 2025
Discover the most popular places to visit in North Clayton

St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do

St. Louis Ghost Tour: Sinister Sins & Shadows

Best of St. Louis Small Group Tour w/ Arch & River Cruise






















