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Find Business Hotels in Panhandle, TX
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Our top choices for Panhandle business-friendly hotels
9.2 out of 10, Wonderful, (1365)
"We like to stay there when we head to Prescott, Arizona. It is convenient and has many restaurants around to chose from! The staff is super nice. "
Charles
$91 nightly
The price is $104
Dec 17 - Dec 18
Total with taxes and fees
Holiday Inn Express & Suites Amarillo West by IHG
Holiday Inn Express & Suites Amarillo West by IHGAmarillo
9.4 out of 10, Exceptional, (1992)
"Great hotel "
Sara
$93 nightly
The price is $107
Jan 11 - Jan 12, 2026
Total with taxes and fees
9.0 out of 10, Wonderful, (472)
"Clean, quiet property; friendly professional staff. Great location. "
Grant
$97 nightly
The price is $109
Dec 25 - Dec 26
Total with taxes and fees
8.0 out of 10, Very Good, (374)
"Room was clean staff was pleasant "
Brian
$72 nightly
The price is $81
Dec 14 - Dec 15
Total with taxes and fees
Country Inn & Suites by Radisson, Amarillo I-40 West, TX
Country Inn & Suites by Radisson, Amarillo I-40 West, TXAmarillo
9.0 out of 10, Wonderful, (2439)
"nice hotel, nice rooms and comfy beds "
Daniel
$74 nightly
The price is $85
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.4 out of 10, Very Good, (2220)
"Clean rooms, nice stay for the night. "
Carmen
$64 nightly
The price is $74
Dec 14 - Dec 15
Total with taxes and fees
8.0 out of 10, Very Good, (730)
"Staff was nice and loved the area "
Briones
$65 nightly
The price is $75
Dec 21 - Dec 22
Total with taxes and fees
Comfort Inn & Suites Amarillo West near Medical Center
Comfort Inn & Suites Amarillo West near Medical CenterAmarillo
8.6 out of 10, Excellent, (1189)
"breakfast was really nice comfortable room and quiet."
Layne
$63 nightly
The price is $72
Dec 24 - Dec 25
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Panhandle Hotel Reviews
Holiday Inn Express & Suites Amarillo West by IHG
10/10 Excellent
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