Photo by Pat Long

Find hotels in Panhandle, TX from $47

Search over 1 million properties and 550 airlines worldwide.

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Most hotels are fully refundable. Because flexibility matters.

Filter by

Drury Inn & Suites Amarillo
3 out of 5
8540 W Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $108 per night from Oct 31 to Oct 31
30.18 mi from city center
4.6/5 Exceptional! (1,798 reviews)
"The staff are unequally the best around! Many choices for dining close by. There were no hitches with checking in or finding our room and the room was excellent! All in all, the whole experience was like coming home."

Reviewed on Oct 22, 2021

Drury Inn & Suites Amarillo
Courtyard by Marriott Amarillo Downtown
3 out of 5
724 S Polk St, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $89 per night from Oct 31 to Oct 31
24.53 mi from city center
4.4/5 Excellent! (721 reviews)
"Historic building in the entertainment area of downtown. Huge suite with fantastic windows. Only downside was that the beds are VERY hard."

Reviewed on Oct 14, 2021

Courtyard by Marriott Amarillo Downtown
Embassy Suites Amarillo Downtown
3.5 out of 5
550 South Buchanan Street, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $118 per night from Nov 7 to Nov 7
24.2 mi from city center
4.4/5 Excellent! (1,041 reviews)
"Great looking hotel in downtown Amarillo."

Reviewed on Sep 12, 2021

Embassy Suites Amarillo Downtown
You could be seeing lower prices

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Homewood Suites by Hilton Amarillo
3 out of 5
8800 Interstate 40 W, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $80 per night from Nov 12 to Nov 12
30.62 mi from city center
4.3/5 Excellent! (904 reviews)
"Very nice hotel. The King suites are very nice. Mini kitchens are a big plus. I would stay here again."

Reviewed on Oct 21, 2021

Homewood Suites by Hilton Amarillo
Fairfield Inn & Suites Amarillo Airport
2.5 out of 5
1740 Airport Blvd, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $118 per night from Nov 7 to Nov 7
19.35 mi from city center
4.3/5 Excellent! (580 reviews)
"Very nice hotel!!! The lady at the front desk was very helpful!!!!"

Reviewed on Oct 14, 2021

Fairfield Inn & Suites Amarillo Airport
Holiday Inn Express Hotel & Suites Amarillo West, an IHG Hotel
2.5 out of 5
8330 W Amarillo Blvd, Amarillo, TX
Fully refundable
The price is $102 per night from Oct 31 to Oct 31
29.89 mi from city center
4.6/5 Exceptional! (967 reviews)
"Rooms were clean and service was excellent 😊"

Reviewed on Oct 19, 2021

Holiday Inn Express Hotel & Suites Amarillo West, an IHG Hotel
Holiday Inn Amarillo West Medical Center, an IHG Hotel
3 out of 5
8231 W Amarillo Blvd, Amarillo, TX
Fully refundable
The price is $94 per night from Nov 7 to Nov 7
29.83 mi from city center
4.2/5 Very Good! (963 reviews)
"Fast and easy check in."

Reviewed on Oct 14, 2021

Holiday Inn Amarillo West Medical Center, an IHG Hotel
Comfort Suites Amarillo
2.5 out of 5
12 Western Plaza Dr, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $59 per night from Nov 21 to Nov 21
27.16 mi from city center
4.1/5 Very Good! (644 reviews)
"Very nice property."

Reviewed on Sep 13, 2021

Comfort Suites Amarillo
Best Western Santa Fe
2.5 out of 5
4600 E Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $99 per night from Oct 25 to Oct 25
22.08 mi from city center
4.2/5 Very Good! (419 reviews)
"Clean, great bed and good breakfast"

Reviewed on Sep 30, 2021

Best Western Santa Fe
Comfort Inn & Suites
2.5 out of 5
2101 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $84 per night from Nov 1 to Nov 1
23.71 mi from city center
4.3/5 Excellent! (977 reviews)
"Convenient location Needs better windows for noise reduction...."

Reviewed on Oct 8, 2021

Comfort Inn & Suites
Hyatt Place Amarillo-West
3 out of 5
8985 W. AMARILLO BLVD, Amarillo, TX
Fully refundable
The price is $92 per night from Nov 1 to Nov 1
30.34 mi from city center
4.6/5 Wonderful! (611 reviews)
"Will stay here again"

Reviewed on Oct 22, 2021

Hyatt Place Amarillo-West
Best Western Plus Medical Center
2.5 out of 5
7410 W Amarillo Blvd, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $76 per night from Nov 7 to Nov 7
29.16 mi from city center
4.5/5 Wonderful! (636 reviews)
"We had trouble with our Navigation trying to find the hotel, and the manager talked us through every turn to get to the hotel. We also was to upgrade to a suite for $10, because I had made a mistake and reserved a pet friendly room without knowing. We had a very nice dinner that was provided, and ..."

Reviewed on Oct 19, 2021

Best Western Plus Medical Center
La Quinta Inn & Suites by Wyndham Amarillo Airport
2.5 out of 5
9305 East Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $105 per night from Oct 31 to Oct 31
19.6 mi from city center
4.5/5 Wonderful! (954 reviews)
"Simple access Clean, nice room"

Reviewed on Oct 17, 2021

La Quinta Inn & Suites by Wyndham Amarillo Airport
Country Inn & Suites by Radisson, Amarillo I-40 West, TX
3 out of 5
2000 Soncy Road, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $73 per night from Oct 31 to Oct 31
30.2 mi from city center
4.2/5 Excellent! (1,646 reviews)
"All excellent."

Reviewed on Oct 22, 2021

Country Inn & Suites by Radisson, Amarillo I-40 West, TX
Baymont by Wyndham Amarillo East
2.5 out of 5
1700 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $62 per night from Nov 7 to Nov 7
24.03 mi from city center
3.6/5 Good! (987 reviews)
"Things were good here. Room was clean and it was pretty quiet, even being on the main floor. Staff had put me in a room on the second floor, but I told them I couldn’t do the stairs, so they found me a room on the main floor. Everything was good."

Reviewed on Oct 20, 2021

Baymont by Wyndham Amarillo East
La Quinta Inn by Wyndham Amarillo Mid-City
2.5 out of 5
1708 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $62 per night from Nov 4 to Nov 4
23.95 mi from city center
3/5 (990 reviews)
"Easy to locate with plenty of parking. Denny's right next door. Staff was nice. The room was small, but comfortable. A couple of lamps without bulbs. I didn't worry about it. They are in the process of renovations. There's a specific area for pets and provide bags."

Reviewed on Sep 7, 2021

La Quinta Inn by Wyndham Amarillo Mid-City
La Quinta Inn by Wyndham Amarillo West Medical Center
2.5 out of 5
2108 Coulter Dr, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $64 per night from Oct 25 to Oct 25
29.3 mi from city center
3.1/5 (961 reviews)
"Everything was great, would have like being able to eat the waffles for breakfast !!!"

Reviewed on Sep 17, 2021

La Quinta Inn by Wyndham Amarillo West Medical Center
Days Inn by Wyndham Amarillo East
2 out of 5
1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $47 per night from Nov 7 to Nov 7
23.96 mi from city center
3.7/5 Good! (1,605 reviews)
"Very quiet"

Reviewed on Oct 6, 2021

Days Inn by Wyndham Amarillo East
Hotel Panhandle TX I-40
2 out of 5
9696 I-40, Panhandle, TX
9.4 mi from city center
Get rates
Hotel Panhandle TX I-40
My Place Hotel-Amarillo West/ Medical Center, TX
2.5 out of 5
2208 Cinema Drive, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is $82 per night from Nov 1 to Nov 1
29.96 mi from city center
4.5/5 Wonderful! (965 reviews)
"Clean, comfortable, courteous. I’ve already booked my next stay and would recommend the same."

Reviewed on Oct 4, 2021

My Place Hotel-Amarillo West/ Medical Center, TX
Don't see what you're looking for?
See all available properties in Panhandle
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Recent reviews of Panhandle hotels

More trip options