Whether it's beautiful paintings, immaculate sculptures or something a bit different, you're bound to find a piece you love at Pepoli Regional Museum.

This collection of precious artworks in Trapani is well-liked by travelers, so make sure it features on your to-do list. However, don't end your sightseeing there. There are many more options waiting for you to appreciate after Pepoli Regional Museum. Cathedral of San Lorenzo, Trapani-Erice Cable Car Valley Station, and Saline di Trapani and Paceco Natural Reserve are nearby.

Plan a trip to see Pepoli Regional Museum

Price found within the past 48 hours. Click for updated prices.

Alkamuri Posh Hotel & Spa

$857

per person

Dec 11 - Dec 16

found 1 hour ago

Roundtrip non-stop flight included

Boston (BOS) to Palermo (PMO)

9/10 Wonderful! (14 reviews)

Spectacular! Beautiful, clean and modern hotel in a gorgeous mountain town. We loved our stay and can’t recommend enough this hotel. The spa is lovely and the rooftop terrace is fabulous. We will be back!

Reviewed on Sep 25, 2022

Tenute Baglio Passofondo

Save 100% on your flight

$1,002

per person

Dec 11 - Dec 16

found 1 hour ago

Roundtrip non-stop flight included

Boston (BOS) to Palermo (PMO)

9.2/10 Wonderful! (9 reviews)

Beautiful boutique property with views of the rolling hills! We were traveling with two children and the suite was comfortable for us all. Smaller pool but perfect for cooling off. Breakfast was lovely!

Reviewed on Aug 12, 2025

Grand Hotel et Des Palmes

Politeama

$2,905

per person

Dec 28 - Jan 1

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Palermo (PMO)

8.4/10 Very Good! (1,003 reviews)

Lovely rooms and hotel. The bathroom was small. The transfer from train station to hotel which hotel arranged was excessive cost for the 5 minute drive. All staff were friendly and accommodating.

Reviewed on Sep 21, 2025

Browse tours and tickets to explore Pepoli Regional Museum

Tours & day trips

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Egadi Islands Tour: Favignana and Levanzo from Trapani

Free cancellation available

History & culture

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From Trapani: Favignana and Levanzo Island Day Cruise

Free cancellation available

Private & custom tours

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Guided tour of the salt pans of Trapani and the Salt Museum

Free cancellation available

Adventure & outdoor

See all 7 activities

Boat excursions Favignana and Levanzo

Free cancellation available

Classes & workshops

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HandsOn Pasta Cooking class with Sicilian Pesto

Free cancellation available

Popular places to visit

We were lucky enough to find it running. Not only it provides a fast way of getting back to Trapani, but the views are... [decide for yourselves] :)
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Trapani-Erice Cable Car Valley Station

You can take time to visit Trapani-Erice Cable Car Valley Station during your travels to Casa Santa. Wander the seaside and beaches in the area.

Basilica-Sanctuary of Maria Santissima Annunziata

You can learn about the history of Trapani with a trip to Basilica-Sanctuary of Maria Santissima Annunziata. While you're in the area, stroll along the waterfront.

Stadio Polisportivo Provinciale

Catch an event at Stadio Polisportivo Provinciale during your trip to Casa Santa. Wander the seaside and beaches in the area.

Triton's Fountain

Triton's Fountain is just one of the places to see in Trapani, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the waterfront.

Piazza Vittorio Emanuele

You can learn about the history of Trapani with a visit to Piazza Vittorio Emanuele. While you're in the area, stroll along the waterfront.

Villa Regina Margherita

Villa Regina Margherita is just one of the places to see in Trapani, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the waterfront.