Port Byron Vacations from $588

Book a Hotel + Flight or Car together to unlock savings

Photo by TnT Travel
  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Port Byron Vacation

Our vacation packages to Port Byron allow you to customize your own adventure. Tailor your getaway to suit your needs and interests and make the most of your time in this wonderful city. Fill up your itinerary with visits to Buffalo Bill Museum, Byron Hills Golf Course and Illiniwek Forest Preserve, some of the attractions you really should see during a trip to Port Byron. Whoever you're taking time off with and whatever you want to spend, your dream Port Byron vacation is just clicks away with Expedia.

The Latest Port Byron vacation packages

Price found within the past 48 hours. Click for updated prices.
Econo Lodge
Hyatt Place East Moline Quad Cities
Decker Hotel & Bar
Courtyard by Marriott Bettendorf
Rhythm City Casino Resort
Don't see what you're looking for?
See all available trips from Columbus to Port Byron
View all trips

Discover the most popular places to visit in Port Byron

Port Byron Hotel Deals

Mississippi River Retreat w/ Views: Walk to Water

Mississippi River Retreat w/ Views: Walk to Water

3 out of 5
Port Byron
Mississippi River Retreat w/ Views: Walk to Water
Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

3.5 out of 5
1415 River Dr, Moline, IL
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $99 total per night from Nov 20 to Nov 21
$99 total
Nov 20 - Nov 21
Total with taxes and fees
9/10 Wonderful! (1,208 reviews)
The room was clean and spacious. The bed is super comfortable with enough pillows. Hot water every time we turned on the tap and shower.

Reviewed on Nov 2, 2025

Wyndham Moline on John Deere Commons
La Quinta Inn by Wyndham Davenport & Conference Center

La Quinta Inn by Wyndham Davenport & Conference Center

3 out of 5
3330 E Kimberly Rd, Davenport, IA
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Nov 13 to Nov 14
$66 total
Nov 13 - Nov 14
Total with taxes and fees
7.2/10 Good! (1,028 reviews)
Awesome guest service thanks 🙏

Reviewed on Oct 29, 2025

La Quinta Inn by Wyndham Davenport & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Port Byron Vacation Packages

Port Byron Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Quad City Intl. Airport (MLI)
Population
1,650
Top Sights
TPC Deere Run Golf Course, Cordova Dragway Park and Illiniwek Forest Preserve

More vacations you might like

Frequently asked questions

How much does a Port Byron vacation package cost?
You'll find cheap prices from $588 on Expedia for your Port Byron escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Port Byron costs.
What are the cheapest months to go to Port Byron?
You can typically find reduced prices and better availability in December, January and February. Take a look at our cheap Port Byron vacation packages and you could score some great off-season discounts.
How many days is enough for Port Byron?
With a well-planned schedule, you can easily tick off the main Port Byron attractions in a handful of days. But if you prefer to venture off the beaten track or go on day tours, consider booking your Port Byron vacation for longer.
How to find the best Port Byron package deals?
Begin your search for a Port Byron package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Port Byron package deal right away, simply switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Port Byron escape off to a flying start.
Is it cheaper to book a Port Byron vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll typically land a better deal than booking each component individually. And you'll still enjoy the flexibility to create a customized Port Byron vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Port Byron?
If you're planning a spur-of-the-moment Port Byron vacation, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find terrific deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Port Byron vacation packages?
Your Port Byron trip should be a relaxing escape from your daily routine, not a reason for money worries. So to give you extra flexibility, we've joined up with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.