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Search Vacation Homes in Port Saint Lucie

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Dec 19 - Dec 21
In two weeks
Dec 26 - Dec 28
In one month
Jan 9 - Jan 11
In two months
Feb 6 - Feb 8

Our top choices for Port Saint Lucie vacation homes

Outdoor pool, pool umbrellas, sun loungers
Sheraton PGA Vacation Resort, Port St. Lucie

Vacation Home in Port Saint Lucie

Sheraton PGA Vacation Resort, Port St. Lucie
3.5 star property
9.0 out of 10, Wonderful, (646)
"Was very happy with our stay"
United States
matthew
$119 nightly
The price is $133
Dec 21 - Dec 22
Total with taxes and fees
Sheraton PGA Vacation Resort, Port St. Lucie
Interior
Mini-Apartment

Vacation Home in Oak Hammock

Mini-Apartment
8.6 out of 10, Excellent, (4)
"The place was great for me. Quite private and clean. It is close to 95 interstate and close to clover park. I was enjoying spring training and the beach. Host was excellent!"
United States
Robert L.
$128 nightly
The price is $140
Dec 16 - Dec 17
Total with taxes and fees
Mini-Apartment
Smart TV, DVD player
Cozy Oasis

Vacation Home in Port St. Lucie

Cozy Oasis
9.0 out of 10, Wonderful, (59)
"Good host. Nice house. "
United States
Paul T.
$248 nightly
The price is $274
Dec 20 - Dec 21
Total with taxes and fees
Cozy Oasis
Fridge, microwave, oven, stovetop
CHEERFUL 3 BEDROOM HOME

Vacation Home in Port St. Lucie

CHEERFUL 3 BEDROOM HOME
9.0 out of 10, Wonderful, (12)
"Nice home, convenient location, fair price. Communication was very good and very much appreciated."
United States
Dave R.
$285 nightly
The price is $315
Dec 12 - Dec 13
Total with taxes and fees
CHEERFUL 3 BEDROOM HOME
Fridge, microwave, oven, stovetop
3-bedroom house, 3 bathroom beautiful peaceful home in Port St. Lucie.

Vacation Home in Sandhill Crossing

3-bedroom house, 3 bathroom beautiful peaceful home in Port St. Lucie.
9.6 out of 10, Exceptional, (8)
"Great location for us with golf and town nearby. Hostess was responsive and easy to work with. We'd stay again, nice house, clean and well equipped."
United States
Kelly N.
$262 nightly
The price is $291
Jan 9 - Jan 10, 2026
Total with taxes and fees
3-bedroom house, 3 bathroom beautiful peaceful home in Port St. Lucie.
Fridge, microwave, oven, stovetop
BR Tropical Oasis in Port St Lucie

Vacation Home in Port Saint Lucie

BR Tropical Oasis in Port St Lucie
2.0 star property
10.0 out of 10, Exceptional, (2)
"We are a construction company that had workers in from out of town and the place was great "
United States
Sabrina B.
$477 nightly
The price is $527
Dec 14 - Dec 15
Total with taxes and fees
BR Tropical Oasis in Port St Lucie
Fridge, microwave, oven, stovetop
Treasure Coast-Blue House Relax

Vacation Home in Northport Village

Treasure Coast-Blue House Relax
7.6 out of 10, Good, (7)
"Very clean and accommodating. "
United States
Gregory S.
$298 nightly
The price is $329
Dec 12 - Dec 13
Total with taxes and fees
Treasure Coast-Blue House Relax
Dining
Charming 2-bedroom guesthouse with AC, WiFi in popular Port St. Lucie “private”

Vacation Home in Port St. Lucie

Charming 2-bedroom guesthouse with AC, WiFi in popular Port St. Lucie “private”
7.4 out of 10, Good, (6)
"Private quaint"
United States
Jack H.
$155 nightly
The price is $171
Dec 12 - Dec 13
Total with taxes and fees
Charming 2-bedroom guesthouse with AC, WiFi in popular Port St. Lucie “private”
1 bedroom, WiFi, bed sheets
La Dolce Vita Studio

Vacation Home in Port St. Lucie

La Dolce Vita Studio
9.4 out of 10, Exceptional, (10)
"Great location.Room is excellent with all basic needs.Will book again."
United States
james h.
$246 nightly
The price is $273
Jan 1 - Jan 2, 2026
Total with taxes and fees
La Dolce Vita Studio
Smart TV
Treasure Coast 1/1 Apartment - Beach, Golf & Relax

Vacation Home in Woodland Trails

Treasure Coast 1/1 Apartment - Beach, Golf & Relax
9.6 out of 10, Exceptional, (9)
"Brand new property, convenient location."
United States
Jason M.
$184 nightly
The price is $204
Jan 1 - Jan 2, 2026
Total with taxes and fees
Treasure Coast 1/1 Apartment - Beach, Golf & Relax
Indoor spa tub
Poolside King Private Room in PSL

Vacation Home in Port St. Lucie

Poolside King Private Room in PSL
10.0 out of 10, Exceptional, (2)
"David's home is very clean, with up-to-date interior decorating that is really attractive and calming. The screened in pool is lovely to use and relaxing just to watch from the dining area. The electronic keyless entry is the best I've ever experienced! Same for the washer and dryer. And David is such a wonderful person and REALLY cares that you are comfortable. He responded very quickly the couple of times I texted. And he met me at check in which I really appreciated."
United States
mary t.
$159 nightly
The price is $176
Dec 15 - Dec 16
Total with taxes and fees
Poolside King Private Room in PSL
Interior
Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly

Vacation Home in Lyngate

Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly
8.8 out of 10, Excellent, (5)
"We had an excellent stay as the house was very clean and the check in process was seamless. We appreciated all of Key's assistance."
United States
jmozden M.
$193 nightly
The price is $213
Dec 13 - Dec 14
Total with taxes and fees
Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly
Property grounds
Beautiful and spacious 4BR house in Port St. Lucie, FL

Vacation Home in Port St. Lucie

Beautiful and spacious 4BR house in Port St. Lucie, FL
8.4 out of 10, Very Good, (6)
"Very nice house great staying "
United States
Mario T.
$289 nightly
The price is $319
Dec 14 - Dec 15
Total with taxes and fees
Beautiful and spacious 4BR house in Port St. Lucie, FL
Fridge, microwave, oven, stovetop
Peaceful Cozy Modern 3 Bed Home

Vacation Home in Sandhill Crossing

Peaceful Cozy Modern 3 Bed Home
10.0 out of 10, Exceptional, (7)
"We loved our stay here! The home was beautiful and clean and even nicer than the photos. Communication was easy and answered very quickly. I would definitely recommend this place. "
United States
Carmen
$307 nightly
The price is $339
Dec 14 - Dec 15
Total with taxes and fees
Peaceful Cozy Modern 3 Bed Home
Outdoor pool, a heated pool
Beach like you've never seen! Heated pool/spa!

Vacation Home in Port St. Lucie

Beach like you've never seen! Heated pool/spa!
10.0 out of 10, Exceptional, (31)
"The house was amazing. Despite not being close to the beach it felt beachy, which we really liked. We had everything we needed. "
United States
Betsy G.
$463 nightly
The price is $512
Dec 15 - Dec 16
Total with taxes and fees
Beach like you've never seen! Heated pool/spa!
Interior
Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie

Vacation Home in Sandpiper Bay

Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie
10.0 out of 10, Exceptional, (17)
"We threw our daughter's 3 year old birthday party here and the home was perfect for a festive weekend close to her grandparents. The home was exceptionally clean, the pool was awesome, highly recommended!"
United States
Eduardo S.
$339 nightly
The price is $375
Dec 15 - Dec 16
Total with taxes and fees
Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie
TV
River Park Marine-House Vacation, 3B, 2B.

Vacation Home in River Park

River Park Marine-House Vacation, 3B, 2B.
8.0 out of 10, Very Good, (1)
$326 nightly
The price is $360
Dec 12 - Dec 13
Total with taxes and fees
River Park Marine-House Vacation, 3B, 2B.
Exterior
The Poolside Escape (Near Beaches)

Vacation Home in Floresta Gardens

The Poolside Escape (Near Beaches)
2.0 star property
$389 nightly
The price is $389
Dec 15 - Dec 16
Total with taxes and fees
The Poolside Escape (Near Beaches)
Smart TV
Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie

Vacation Home in Lyngate

Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie
9.0 out of 10, Wonderful, (4)
"The house was comfortable. "
United States
C M.
$319 nightly
The price is $353
Dec 31 - Jan 1, 2026
Total with taxes and fees
Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie
Beach
Lush | Tropical | Modern Home w/ Heated Pool & Spa

Vacation Home in Sandhill Crossing

Lush | Tropical | Modern Home w/ Heated Pool & Spa
10.0 out of 10, Exceptional, (18)
"Great place to stay, private and relaxing. Location is close to just about everything. Will stay again :)"
United States
Scott T.
$477 nightly
The price is $528
Dec 12 - Dec 13
Total with taxes and fees
Lush | Tropical | Modern Home w/ Heated Pool & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Port Saint Lucie Hotel Reviews

Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie

10/10 Excellent
"Great stay! Very friendly staff "
Giovanni 2-night trip
Posted 2 days ago
Residence Inn by Marriott Port St. Lucie

Find out more about Port Saint Lucie

Port Saint Lucie Vacation Homes information

Number of reviews
821
Accommodation
298 Vacation Homes
Lowest Price
$133
Highest Price
$528

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