Search Vacation Homes in Port Saint Lucie

    price find illustration
    Upfront pricing
    Our total price for your stay includes taxes and fees
    deals illustration
    Treat yourself
    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Vacation Homes in Port Saint Lucie

Sheraton PGA Vacation Resort, Port St. Lucie

3.5 star property
9.0 out of 10, Wonderful, (616)
"The stay was awesome stayed there twice "
$97 nightly
The price is $109
Jul 9 - Jul 10
Total includes taxes and fees
Sheraton PGA Vacation Resort, Port St. Lucie

Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach

9.0 out of 10, Wonderful, (38)
"Charming, fantastic owners, clear communication, and a beautiful location! Perfect for a couples getaway!"
Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach

Cozy Oasis

9.4 out of 10, Exceptional, (45)
"This place was so beautiful and had everything we needed. We will be visiting again ! "
$286 nightly
The price is $316
Jul 14 - Jul 15
Total includes taxes and fees
Cozy Oasis

Paradise Palms 2

10.0 out of 10, Exceptional, (28)
"It was a great place to stay while visiting family. "
Paradise Palms 2

Joyful 4 bed 2 bath home in the beautiful Port St.Lucie

10.0 out of 10, Exceptional, (11)
"Beautiful property! When we needed to contact the host he responded immediately. We were in town for a week for our daughter’s wedding and this was the perfect place to stay! All the comforts of home, exactly what we hoped for! Thank you for making our stay a memorable one!"
Joyful 4 bed 2 bath home in the beautiful Port St.Lucie

3 Bedroom home with large pool. Great location.

9.0 out of 10, Wonderful, (7)
"Stay was wonderful. Stores were close by for general shopping or groceries. Pool was wonderful. House had had everything we need to cook with, quite neighborhood "
3 Bedroom home with large pool. Great location.

Private Villa | Pool + Hot Tub + Sleeps 20

10.0 out of 10, Exceptional, (10)
"This was a gorgeous spacious home. Everything we needed was provided and extras! Clean, roomy, and very comfortable. The area was exceptional as well. Our hosts were very accommodating and quick to respond with questions and concerns we had. We will stay here again next time we come to the area. "
Private Villa | Pool + Hot Tub + Sleeps 20

Entire home with pool for long and short stay. Fun for everyone.

9.8 out of 10, Exceptional, (35)
"had everything we needed for a stay while visiting family, food and shopping close by! love the salt water pool!"
Entire home with pool for long and short stay. Fun for everyone.

9 Mi to Clover Park: Poolside Paradise!

9.0 out of 10, Wonderful, (2)
"House was clean. Great location. Pool was nice. It had everything you need to cook."
9 Mi to Clover Park: Poolside Paradise!

3-bedroom vacation home 12 minutes from Port St. Lucie Botanical Gardens

10.0 out of 10, Exceptional, (12)
"It was very clean and had everything we needed "
3-bedroom vacation home 12 minutes from Port St. Lucie Botanical Gardens

"The Sandpiper" Your Home Away From Home

9.6 out of 10, Exceptional, (30)
"We needed a nice home with a pool near family for a few days and this was perfect!!"
"The Sandpiper" Your Home Away From Home

Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie

10.0 out of 10, Exceptional, (3)
"The house was comfortable. "
Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie

Peaceful 3BD & 2BA with Salt Water Heated Pool, 35 min.'s from Jensen Beach!

9.6 out of 10, Exceptional, (11)
"Great host . Great house ! "
Peaceful 3BD & 2BA with Salt Water Heated Pool, 35 min.'s from Jensen Beach!

Riverside Retreat: 4BR/3BA with Private Dock and Boat Lift

9.0 out of 10, Wonderful, (4)
"Nice property and as advertised. "
$466 nightly
The price is $515
Jul 9 - Jul 10
Total includes taxes and fees
Riverside Retreat: 4BR/3BA with Private Dock and Boat Lift

Waterfront Home, Private Dock; 3 miles to Tradition Town Center

10.0 out of 10, Exceptional, (17)
"Beautiful and comfortable home. A great base for our spring training family reunion."
Waterfront Home, Private Dock; 3 miles to Tradition Town Center

Charming Newly built 4bedroom house with WiFi and AC in brilliant Port St. Lucie

2.0 star property
9.0 out of 10, Wonderful, (2)
"Wendys house is amazing, a brand new four bedroom house with a pool, privacy fence, two garages and awesome hosts. Check in was a breeze and everything was so clean and ready for us. I have used short term rentals worldwide for over ten years and this was by far one of the best homes I have stayed in."
Charming Newly built 4bedroom house with WiFi and AC in brilliant Port St. Lucie

The Beach House

10.0 out of 10, Exceptional, (3)
"What a beautiful home!! We came to visit family in the area, as a mom of 3 boys, with a handicap sister, this was perfect. Amazing communication, cannot stress enough. Hanging in the pool, open doorwall to tv to cheer on our football teams was just fantastic for this crew. Many of my family are already looking to book when in town to visit. Thank you so much for a great time. "
The Beach House

Tropical Family Escape with Pool, Arcade Games and Outdoor Lounge

2.5 star property
10.0 out of 10, Exceptional, (8)
"Loved, loved this place. Everything was a 10!"
Tropical Family Escape with Pool, Arcade Games and Outdoor Lounge

A Slice of Paradise pool and pool table

9.8 out of 10, Exceptional, (20)
"Perfect place. Room for four guys all had own room. Very comfortable "
A Slice of Paradise pool and pool table

4-bedroom house in superb Port St. Lucie with WiFi, AC

8.4 out of 10, Very Good, (5)
"Worked as a great place to stay while working in the area."
$580 nightly
The price is $642
Aug 3 - Aug 4
Total includes taxes and fees
4-bedroom house in superb Port St. Lucie with WiFi, AC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in