Potrero Hill Vacations from $220

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Your Potrero Hill Vacation

Make planning your travels stress-free by locking in a vacation package to Potrero Hill. Let us take care of the details, so you can focus on savoring everything this neighborhood has to offer. When it's time to take in the sights, you'll find a lot of popular attractions nearby including Oracle Park, San Francisco Museum of Modern Art and Exploratorium. Tick off one or all during your trip to Potrero Hill. Expedia is here to put your plans into action. Book your ultimate Potrero Hill vacation today.

The Latest Potrero Hill Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aqua Breeze Inn

Aqua Breeze Inn

2.5 out of 5
Westside Santa Cruz
Save 100% on your flight
Price was $350, price is now $220 per person
$220
per person
Jan 22 - Jan 24
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Jose (SJC)
8/10 Very Good! (1,002 reviews)
Parking was easy, but I did need to leave early cause of a family emergency and wasn't able to get a refund, but the staff was nice about it. Just wish we could specify on website

Reviewed on Dec 3, 2025

Montage Healdsburg

Montage Healdsburg

5 out of 5
Save 100% on your flight
Price was $2,060, price is now $1,181 per person
$1,181
per person
Feb 12 - Feb 15
found 12 hours ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.6/10 Exceptional! (113 reviews)
Clean room, kind and helpful staff. Nice ambiance in vineyard.

Reviewed on Nov 30, 2025

Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley

5 out of 5
Save 100% on your flight
Price was $2,224, price is now $1,383 per person
$1,383
per person
Feb 13 - Feb 19
found 8 hours ago
Roundtrip flight included
New York (NYC) to San Francisco (SFO)
9.6/10 Exceptional! (59 reviews)
Enjoyed our stop here and the staff was pleasant. Clean facilities and nice entertaining layout.

Reviewed on Nov 23, 2025

San Francisco Proper Hotel

San Francisco Proper Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $626, price is now $397 per person
$397
per person
Jan 15 - Jan 18
found 21 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
8.8/10 Excellent! (789 reviews)
Despite the surround area, the hotel itself is very welcoming and everyone very friendly and above and beyond to make you feel welcome. Rooms were clean and good amenities. I didn’t have a reservation for the rooftop but the team squeezed me in - great views and cocktails!

Reviewed on Nov 23, 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,553, price is now $1,008 per person
$1,008
per person
Feb 14 - Feb 17
found 14 hours ago
Roundtrip flight included
New York (NYC) to San Francisco (SFO)
9.2/10 Wonderful! (470 reviews)
The staff was incredible and we loved all of the design touches in the room. The attention to detail was impressive.

Reviewed on Dec 7, 2025

Where to stay in Potrero Hill

Find the best Potrero Hill areas and neighborhoods for the activities you enjoy most. Learn more about Potrero Hill
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Potrero Hill Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
$119 nightly
The price is $140 total per night from Dec 14 to Dec 15
$140 total
Dec 14 - Dec 15
Total with taxes and fees
8.8/10 Excellent! (4,919 reviews)
Clean room, courteous staff, walking distance to lots of eateries.

Reviewed on Dec 4, 2025

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $193 total per night from Dec 18 to Dec 19
$193 total
Dec 18 - Dec 19
Total with taxes and fees
8.8/10 Excellent! (7,164 reviews)
The room and hotel was clean. The staff was friendly. The hotel was a great location. Couldn’t ask for anything else.

Reviewed on Dec 5, 2025

Hotel Riu Plaza Fisherman's Wharf
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4 out of 5
200 Marina Blvd Berkeley CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $137 total per night from Dec 15 to Dec 16
$137 total
Dec 15 - Dec 16
Total with taxes and fees
8.2/10 Very Good! (3,873 reviews)
Excellent breakfast

Reviewed on Dec 3, 2025

DoubleTree by Hilton Hotel Berkeley Marina
See all 4,937 properties in Potrero Hill
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Potrero Hill

Anchor Brewing Company

Anchor Brewing Company

During your trip to San Francisco, you can search for that perfect souvenir at Anchor Brewing Company. Discover the top-notch restaurants and acclaimed art scene in this vibrant area.

Anchor Brewing Company

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
84% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

$58
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
Alcatraz Ticket with Roundtrip Ferry & Hop-On Hop-Off

Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour

$120
per adult
86% of travellers recommend
Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.