Sant'Eustachio Vacations from $594

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Your SantEustachio Vacation

A well-liked picturesque neighborhood, SantEustachio is all about cafes, history and bars and pubs. Lock in a vacation package to SantEustachio and get set to discover all of that and more. Start your trip to SantEustachio by checking out nearby attractions such as St. Peters Basilica, Roman Forum and Pantheon. Stop daydreaming and start doing. When you're ready to book your dream vacation to SantEustachio, Expedia is here to help.

The Latest Sant'Eustachio Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The B Place Hotel

The B Place Hotel

3 out of 5
Rome City Centre
Price was $889, price is now $594 per person
$594
per person
Jan 18 - Jan 24
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
8.2/10 Very Good! (484 reviews)
The receptionist (Thierry) is very nice and helpful. And their breakfast is very good.

Reviewed on Nov 22, 2025

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Price was $1,110, price is now $675 per person
$675
per person
Feb 12 - Feb 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
The staff was amazing. The room was perfectly lovely! Would stay there again!

Reviewed on Nov 21, 2025

Hotel Forum

Hotel Forum

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,572, price is now $980 per person
$980
per person
Feb 17 - Feb 23
found 19 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Rome (FCO)
8.6/10 Excellent! (1,001 reviews)
Perfect location, excellent staff and service, comfortable beds, and wonderful food on the rooftop.

Reviewed on Nov 2, 2025

Vibe Nazionale

Vibe Nazionale

3 out of 5
Rome City Centre
Price was $1,047, price is now $702 per person
$702
per person
Jan 18 - Jan 24
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
8/10 Very Good! (65 reviews)
It’s modern and comfy

Reviewed on Oct 20, 2025

Hotel Giolli Nazionale

Hotel Giolli Nazionale

3 out of 5
Rome City Centre
Price was $1,016, price is now $702 per person
$702
per person
Jan 18 - Jan 24
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
8.2/10 Very Good! (134 reviews)
Loved this place! Great accommodations and very clean and comfortable! Would rate it wonderful!!

Reviewed on Oct 23, 2025

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Where to stay in Sant'Eustachio

Find the best Sant'Eustachio areas and neighborhoods for the activities you enjoy most. Learn more about Sant'Eustachio
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

9 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Sant'Eustachio Hotel Deals

Argentina Residenza Style Hotel

Argentina Residenza Style Hotel

4 out of 5
Via di Torre Argentina 47 Rome RM
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $237 total per night from Dec 18 to Dec 19
$237 total
Dec 18 - Dec 19
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
Perfect spot in the middle of everywhere.

Reviewed on Nov 18, 2025

Argentina Residenza Style Hotel
Hotel Navona

Hotel Navona

3 out of 5
Via dei Sediari 8 Rome RM
$104 nightly
The price is $128 total per night from Dec 14 to Dec 15
$128 total
Dec 14 - Dec 15
Total with taxes and fees
8.8/10 Excellent! (1,009 reviews)
Clean room. Staff very courteous and helpful. Hotel very central.

Reviewed on Nov 18, 2025

Hotel Navona
Hotel Smeraldo

Hotel Smeraldo

3 out of 5
Via dei Chiavari 20 Rome RM
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $153 total per night from Dec 10 to Dec 11
$153 total
Dec 10 - Dec 11
Total with taxes and fees
9.4/10 Exceptional! (1,015 reviews)
The breakfast was amazing. The rooms were very clean.

Reviewed on Nov 22, 2025

Hotel Smeraldo
See all 15,933 properties in Sant'Eustachio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Sant'Eustachio

Palazzo Madama

Palazzo Madama

After visiting Palazzo Madama, make a plan to see the other sights and activities in Rome. Stroll along the riverfront or visit the churches in this vibrant area.

Palazzo Madama
Sant'Ivo alla Sapienza

Sant'Ivo alla Sapienza

You can learn about the history of Rome with a stop at Sant'Ivo alla Sapienza. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Sant'Ivo alla Sapienza

Chiesa di Sant’Andrea della Valle

After visiting Chiesa di Sant’Andrea della Valle, make a plan to see the other sights and activities in Rome. Discover the acclaimed theater scene and notable monuments in this vibrant area.

Chiesa di Sant’Andrea della Valle

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$53
per adult
82% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$39
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.