San Cosme y Damian Vacations from $228

Book a Hotel + Flight or Car together to unlock savings

The Latest San Cosme y Damian vacation packages

Price found within the past 48 hours. Click for updated prices.
The LINQ Hotel & Casino – A Caesars Rewards Destination

The LINQ Hotel & Casino – A Caesars Rewards Destination

4 out of 5
Las Vegas Strip
Price was $688, price is now $228 per person
$228
per person
Feb 2 - Feb 5
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Las Vegas (LAS)
7.8/10 Good! (17,196 reviews)
The room was OK. Space is extremely small, but clean and comfortable. It’s also extremely affordable. Not the place to be if you’re looking for a luxury stay but definitely something to consider if you just want a clean space to sleep.The major highlight of the hotel is that it is located in the center of everything!

Reviewed on Nov 14, 2025

The Shelborne By Proper, a Member of Design Hotels

The Shelborne By Proper, a Member of Design Hotels

4 out of 5
South Beach
Price was $2,386, price is now $980 per person
$980
per person
Jan 14 - Jan 18
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Miami (MIA)
9.8/10 Exceptional! (39 reviews)
Lovely property. Staff service inconsistent overall. Room was not serviced one day. On the day there was construction above pool area, no notice was sent out. Pool area staff/manager and construction crew didn't seem to be on the same page.

Reviewed on Nov 13, 2025

Hawks Cay Resort

Hawks Cay Resort

4 out of 5
Price was $2,204, price is now $918 per person
$918
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Miami (MIA)
8/10 Very Good! (1,011 reviews)
Room was clean and spacious. Property did not have available microwave for guest. House keeping was good but did not replace soap or drinking glass. Gym not located in main hotel area and it closes at 5pm. Overall property is beautiful and good amenities.

Reviewed on Nov 7, 2025

Creekside Inn

Creekside Inn

2.5 out of 5
Price was $782, price is now $347 per person
$347
per person
Dec 16 - Dec 21
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Miami (MIA)
8/10 Very Good! (1,009 reviews)
The staff was very courteous. Room was older but clean and bed was comfortable. ~ tile floors needed to be cleaned with another product- they felt slimy. Shower head needed to be replaced

Reviewed on Nov 11, 2025

The Retreat Collection at 1 Hotel & Homes South Beach

The Retreat Collection at 1 Hotel & Homes South Beach

5 out of 5
South Beach
Price was $20,177, price is now $9,078 per person
$9,078
per person
Jan 25 - Jan 30
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Miami (MIA)
8/10 Very Good! (1 review)
Don't see what you're looking for?
See all available trips from Columbus to San Cosme y Damian
View all trips

Discover the most popular places to visit in San Cosme y Damian

Buenaventura Suarez Planetarium

You can spend time browsing the exhibits at Buenaventura Suarez Planetarium during your travels in San Cosme y Damian. Take in the museums while you're in the area.

Buenaventura Suarez Planetarium

San Cosme y Damian Hotel Deals

Awa Resort Hotel

Awa Resort Hotel

4 out of 5
Ruta 1 Km 367, Calles Tajy y Naranjal, Encarnacion
Fully refundable
$126 nightly
The price is $139 total per night from Dec 7 to Dec 8
$139 total
Dec 7 - Dec 8
Total with taxes and fees
8.8/10 Excellent! (112 reviews)
Awesome stay !!

Reviewed on Aug 31, 2025

Awa Resort Hotel
Hotel Luxsur

Hotel Luxsur

3.5 out of 5
Jorge Memmel 661, c/ Independencia Nacional, Encarnacion
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Nov 16 to Nov 17
$74 total
Nov 16 - Nov 17
Total with taxes and fees
8.8/10 Excellent! (152 reviews)
The breakfast was good. rooms were clean

Reviewed on Feb 6, 2025

Hotel Luxsur
Carnaval Hotel Casino

Carnaval Hotel Casino

3.5 out of 5
Av. Irrazabal, 750, Encarnacion
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $69 total per night from Nov 16 to Nov 17
$69 total
Nov 16 - Nov 17
Total with taxes and fees
9.2/10 Wonderful! (158 reviews)
Nice and very comfortable hotel! Enjoy the pool and steam bath very much. Would defenitly stay there again! But it should be mentioned that the Junior Suites with River view don't have a RIVER VIEW :-(.

Reviewed on Nov 5, 2025

Carnaval Hotel Casino
See all 32 properties in Itapúa Department
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Cosme y Damian Vacation Packages

San Cosme y Damian Essential Information

Language
Spanish
Currency
Paraguayan guaranís
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Libertador General Jose de San Martin Airport (PSS)
Population
2,200
Max Temp Winter
70ºF
Max Temp Summer
90ºF

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a San Cosme y Damian vacation package cost?
You can pick up a vacation package to this popular destination from $228 on Expedia. But how much your vacation to San Cosme y Damian costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to San Cosme y Damian?
February, March and August are the best times to look for cheap San Cosme y Damian vacation packages. Traveling in quieter periods means you can generally find reduced prices on accommodations and flights.
How many days is enough for San Cosme y Damian?
The ideal duration for your San Cosme y Damian vacation depends on what you'd like to see. Generally, a handful of days to a week will give you enough time to tick off all the main attractions and explore some hidden treasures along the way.
How to find the best San Cosme y Damian package deals?
Use Expedia's filters to help you find some of the best San Cosme y Damian package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for San Cosme y Damian package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a San Cosme y Damian vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your car rental, flight and hotel into one great-value price and you could save hundreds of dollars. You'll usually land a better deal than booking each component separately. And you'll still get the flexibility to create a personalized San Cosme y Damian vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to San Cosme y Damian?
Secure incredible bargains by reserving your flights in advance with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment San Cosme y Damian getaway.
Does Expedia offer Book Now, Pay Later San Cosme y Damian vacation packages?
Your San Cosme y Damian trip should be a relaxing escape from your daily routine, not a source of money worries. So to give you extra flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.