San Isidro Vacations from $901

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Your San Isidro Vacation

Say goodbye to the hassle of planning and hello to a San Isidro vacation package. With the finer details organized before you take off, you can focus on discovering every inch of this city, starting with Cartagena Walled City, which is great for views, dining and bars and pubs. If a sightseeing tour is part of the program during your trip to San Isidro, stop by leading attractions like San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium. Whoever you're heading away with and whatever you want to spend, your ultimate San Isidro vacation is just a few clicks away with Expedia.

The Latest San Isidro Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Boutique Patio Corao By GEH Suites

Cartagena Walled City

Save 100% on your flight

$901

per person

Nov 14 - Nov 18

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)

9.4/10 Exceptional! (23 reviews)

We loved our 2 night stay, the room exceeded our expectations and the staff was always available and friendly. Safe, secure charming hotel in the quieter San Diego area of Old City. We would a stay again.

Reviewed on Mar 28, 2026

Decameron Baru - All inclusive

Save 100% on your flight

$1,638

per person

Jan 4 - Jan 8

found 1 day ago

Roundtrip flight included

Miami (MIA) to Cartagena (CTG)

7.6/10 Good! (404 reviews)

The property it’s very good

Reviewed on Sep 28, 2026

Casa Bali Castillo View Private Pool & R

Pie del Cerro

Save 100% on your flight

$1,100

per person

Dec 3 - Dec 7

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)

10/10 Exceptional! (1 review)

Excelente ubicación, buenas instalaciones, en la recepción tanto Omar como la recepcionista fueron muy amables en todo momento.

Reviewed on Feb 17, 2026

Casa Maguey with Jacuzzi and Panoramic View of the Bay

Cartagena Walled City

Save 100% on your flight

$2,401

per person

Dec 27 - Jan 1

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Cartagena (CTG)

No reviews

Isla del Pirata - Oficina de Reserva

Save 100% on your flight

$2,983

per person

Jan 4 - Jan 8

found 1 day ago

Roundtrip flight included

Miami (MIA) to Cartagena (CTG)

7.4/10 Good! (9 reviews)

Beautiful place excellent service

Reviewed on Feb 16, 2025

Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro

A coastal cityscape with a prominent skyscraper, a marina with boats, and historic buildings with red-tiled roofs.

Cartagena Walled City

3 out of top 10 points of interest in this area

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

A coastal cityscape with high-rise buildings along a curved shoreline.

Bocagrande

1 out of top 10 points of interest in this area

Boasting the city's most prominent hotels, this upscale area offers shopping at Plaza Bocagrande and Nao Mall, and is close to the popular Ciudad Amurallada. Enjoy various dining options and easy access to the Transcaribe station.

A coastal town with a prominent church featuring a tall bell tower and a domed roof.

Getsemani

Travelers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.

A coastal cityscape with historic buildings, a marina, and a prominent church tower.

Cartagena Centro

Unique features of Cartagena Centro include the museums and historic sites. Make a stop by Plaza Santo Domingo or Bolivar Square while you're exploring the area.

A man playing a guitar on a colorful street with yellow, blue, and pink buildings.

San Diego

San Diego is known for its ample dining options, and you can make a stop by House of Gabriel Garcia Marquez and Las Bovedas while in the area.

San Isidro Hotel Deals

OZ Hotel Collection

6-164 Carrera 2 Cartagena

Fully refundableReserve now, pay when you stay

$99 nightly

$99 total

Oct 28 - Oct 29

Sofitel Barú Cartagena

KM 7 Sector, Porto Nao Cartagena Bolívar

Fully refundableReserve now, pay when you stay

$329 nightly

$329 total

Nov 8 - Nov 9

9.4/10 Exceptional! (827 reviews)

"Muy buena opción para descansar en familia o pareja y tener playa bonita"

Reviewed on Oct 12, 2026

Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

Anillo Vial, Km 12, between Manzanillo Cartagena Bolivar

Fully refundableReserve now, pay when you stay

$290 nightly

$290 total

Nov 11 - Nov 12

See all 4,063 properties in San Isidro

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.