San Isidro Vacations from $609

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Your San Isidro Vacation

Say goodbye to the hassle of planning and hello to a San Isidro vacation package. With the finer details organized before you take off, you can focus on discovering every inch of this city, starting with Cartagena Walled City, which is great for views, dining and bars and pubs. If a sightseeing tour is part of the program during your trip to San Isidro, stop by leading attractions like San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium. Whoever you're heading away with and whatever you want to spend, your ultimate San Isidro vacation is just a few clicks away with Expedia.

The Latest San Isidro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Almirante Cartagena - Colombia

Hotel Almirante Cartagena - Colombia

4.5 out of 5
Bocagrande
Save 100% on your flight
Price was $1,101, price is now $609 per person
$609
per person
May 6 - May 11
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)
8.4/10 Very Good! (1,003 reviews)
I am so pleased to Recommend Almirante! From the Welcoming Smiles of the staff & “Welcome” Drink…to the Singers @La Terrazza & Jholi, a Fabulous Singer at the inside Bar…I stayed 10 days & Unfortunately I don’t speak Spanish well, but everyone tried to accommodate, especially both Raphael’s, so all was well! Clearly Almirante takes pride in Excellent Customer Service as they willingly changed my room to a Quieter area & as my flight was in the Evening I was able to extend my day till 5 pm for a very reasonable rate! the Environment (beautiful plants) & Spotless! This Hotel is right on a main drag, so lots of tourists & shops on one side & the BocaGrande Beach on the other. They offer a huge Buffet Breakfast, but there are many little places to try in the area. All I can say is Gracias to All the Wonderful Staff @Hotel Almirante! I’m SO sad to be Leaving today…

Reviewed on Feb 16, 2026

Decameron Cartagena All Inclusive

Decameron Cartagena All Inclusive

3.5 out of 5
Bocagrande
Save 100% on your flight
Price was $1,473, price is now $772 per person
$772
per person
May 8 - May 13
found 2 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)
6.6/10 (172 reviews)
All the staff always ready to help, great activities and food

Reviewed on Dec 23, 2025

Decameron Baru - All inclusive

Decameron Baru - All inclusive

3.5 out of 5
Price was $2,189, price is now $1,167 per person
$1,167
per person
Apr 24 - Apr 28
found 4 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Cartagena (CTG)
7.8/10 Good! (387 reviews)
Very friendly staff, clean rooms and great atmosphere.

Reviewed on Nov 10, 2025

Pao Pao Cartagena

Pao Pao Cartagena

4 out of 5
Save 100% on your flight
Price was $1,916, price is now $1,026 per person
$1,026
per person
May 16 - May 23
found 18 hours ago
Roundtrip flight included
New York (JFK) to Cartagena (CTG)
9/10 Wonderful! (12 reviews)
The staff were incredible and service was 10+ Very relaxing stay enjoyed snorkeling around the island. Although there are day groups they come in they are quiet and the music played at the beach is very subtle. The food was very good with lots of variety

Reviewed on Jan 26, 2026

Hotel Isla del Encanto

Hotel Isla del Encanto

4 out of 5
Save 100% on your flight
Price was $2,461, price is now $1,327 per person
$1,327
per person
May 5 - May 11
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)
8.8/10 Excellent! (186 reviews)
The hotel is lovely and perfect for a quiet getaway! The staff is exceptional and everything

Reviewed on Feb 3, 2026

Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro
Church of St Peter Claver in Cartagena, Colombia

Cartagena Walled City

3 out of top 10 points of interest in this area
4.5/5(1,184 area reviews)

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

Find hotels in Cartagena Walled City

San Isidro Hotel Deals

InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG

4 out of 5
Bocagrande Carrera 1 No. 5-01 Cartagena Bolivar
Fully refundable
$182 nightly
The price is $182 total per night from Mar 23 to Mar 24
$182 total
Mar 23 - Mar 24
9.4/10 Exceptional! (1,502 reviews)
The property was in a nice turist area of town. The staff was excellent, no matter who-at the door, front desk cleaning services Restaurant waiters, it was pretty modern. We did have a king size bed and it was not Hotel Quality. It was 7/10 compared to other five star hotels and the room itself was ...

Reviewed on Feb 21, 2026

InterContinental Cartagena De Indias by IHG
Hyatt Regency Cartagena

Hyatt Regency Cartagena

4.5 out of 5
Carrera 1 No 12-118 Cartagena CO
$200 nightly
The price is $200 total per night from Mar 7 to Mar 8
$200 total
Mar 7 - Mar 8
9.4/10 Exceptional! (1,449 reviews)
What really stood out was the exceptional staff — everyone was welcoming, attentive, and genuinely kind. The room was spotless and very comfortable, which made the stay even better. Overall, it was a wonderful experience.

Reviewed on Feb 20, 2026

Hyatt Regency Cartagena
Hilton Cartagena

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $179 total per night from Mar 5 to Mar 6
$179 total
Mar 5 - Mar 6
9/10 Wonderful! (1,359 reviews)
Staff was friendly, good exercise room and close to some restaurants. Breakfast buffet is excellent and highly recommended, though some avocado as an option would be good. Lots of pools and a beach to use.

Reviewed on Feb 20, 2026

Hilton Cartagena
See all 3,865 properties in San Isidro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in San Isidro

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Bocagrande Beach

If a restful vacation is part of your travel plans, Bocagrande Beach might be the perfect place to seek out during your trip to Cartagena. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.

Bocagrande Beach
Cartagena de Indias Convention Center "Julio César Turbay Ayala" reflected in the water

Cartagena de Indias Convention Center

Learn about the events happening at Cartagena de Indias Convention Center during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

Cartagena de Indias Convention Center
Carribean landscape on Isla Grande, Rosario Archipelago, Colombia, South America

Isla Grande Beach

Why not spend a carefree afternoon at Isla Grande Beach during your travels in Rosario Islands? You can seek out the snorkeling spots in this relaxing area.

Isla Grande Beach

Things to do

Cartagena Island Hopping : 5-Stop Rosario Island Tour with Lunch

Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch

$68
per adult
78% of travellers recommend
Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch
Cartagena ATV Tour

Cartagena ATV Tour

$135
per adult
96% of travellers recommend
Cartagena ATV Tour
Full-Day Volcano of Totumo

Full-Day Volcano of Totumo With Lunch, 5 pools and prívate Bach

$60
per adult
78% of travellers recommend
Full-Day Volcano of Totumo With Lunch, 5 pools and prívate Bach
See all activities in Cartagena
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.