Sant'Angelo Vacations from $1,195

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Your SantAngelo Vacation

If you're craving a riverside retreat, our SantAngelo vacation packages are just what you need. Whether you want to experience its history, dining or culture, this neighborhood has a bit of something for every traveler. Begin your trip to SantAngelo by heading to nearby attractions such as St. Peters Basilica, Roman Forum and Pantheon. Don't just think about it — turn it into a reality! Book your perfect SantAngelo vacation with Expedia and experience travel your way.

The Latest Sant'Angelo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

Nomentano
Save 100% on your flight
$1,195
per person
Oct 30 - Nov 5
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (318 reviews)
Hotiday Roma Trevi

Hotiday Roma Trevi

Rome City Centre
Save 100% on your flight
$1,505
per person
Oct 28 - Oct 31
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
No reviews
Albergo Etico Roma

Albergo Etico Roma

Flaminio
Save 100% on your flight
$1,386
per person
Nov 1 - Nov 6
found 13 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.8/10 Exceptional! (379 reviews)
Borghese Contemporary Hotel

Borghese Contemporary Hotel

Rome City Centre
Save 100% on your flight
$2,109
per person
Nov 1 - Nov 6
found 13 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.6/10 Exceptional! (138 reviews)
Tree Charme Augusto Boutique Hotel

Tree Charme Augusto Boutique Hotel

Rome City Centre
Save 100% on your flight
$1,217
per person
Nov 24 - Nov 30
found 5 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.6/10 Exceptional! (41 reviews)

Where to stay in Sant'Angelo

Find the best Sant'Angelo areas and neighborhoods for the activities you enjoy most. Learn more about Sant'Angelo
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

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A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

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The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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Sant'Angelo Hotel Deals

Hilton Garden Inn Rome Airport

Hilton Garden Inn Rome Airport

Via Vittorio Bragadin 2 Fiumicino RM
Fully refundableReserve now, pay when you stay
$209 nightly
$241 total
Oct 15 - Oct 16
Total with taxes and fees
Hilton Garden Inn Rome Airport
Hilton Rome Airport

Hilton Rome Airport

Via Arturo Ferrarin 2 Fiumicino RM
$322 nightly
$365 total
Oct 7 - Oct 8
Total with taxes and fees
8.4/10 Very Good! (3,404 reviews)
"Great place to stay within airport grounds. Beautiful rooms. Quiet, Excellent customer service. The gym is decent - primarily machines, dumbbell rack, and cardio. The pool looked very cloudy so we decided not to use it. The executive lounge was a nice touch. We highly recommend the breakfast buffet ..."

Reviewed on Sep 21, 2026

Hilton Rome Airport
Hotel Isola Sacra Rome Airport

Hotel Isola Sacra Rome Airport

Via Della Scafa 416 Fiumicino RM
Fully refundableReserve now, pay when you stay
$206 nightly
$238 total
Oct 20 - Oct 21
Total with taxes and fees
Hotel Isola Sacra Rome Airport
See all 16,661 properties in Sant'Angelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sant'Angelo attractions

Theatre of Marcellus

Find out about the history of Rome when you spend time at Theatre of Marcellus. Experience the acclaimed art scene and fascinating museums in this vibrant area.
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Great Synagogue of Rome

8.0/10 (4 reviews)
You can learn about the history of Rome with a visit to Great Synagogue of Rome. Visit the churches and notable monuments in this vibrant area.
See properties

Area Archeologica del Teatro di Marcello e del Portico d’Ottavia

Find out about the history of Rome when you take a trip to Area Archeologica del Teatro di Marcello e del Portico d’Ottavia. Experience the acclaimed theater scene and fascinating museums in this vibrant area.
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Portico di Ottavia

You can learn about the history of Rome when you stop by Portico di Ottavia. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Fontana delle Tartarughe

Fontana delle Tartarughe is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? Visit the churches and notable monuments in this vibrant area.
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Museo Ebraico di Roma

You can find out about the history of Rome when you stop by Museo Ebraico di Roma. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
See properties

Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Culinary Delights: Cooking Class and Market Food Tour in Rome

Rome Pasta and Gelato Cooking Class a Hands-On Italian Culinary Experience

$87
per adult
100% of travellers recommend
Rome Pasta and Gelato Cooking Class a Hands-On Italian Culinary Experience
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$132
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.