Sant'Angelo Vacations from $1,386

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Your SantAngelo Vacation

If you're craving a riverside retreat, our SantAngelo vacation packages are just what you need. Whether you want to experience its history, dining or culture, this neighborhood has a bit of something for every traveler. Begin your trip to SantAngelo by heading to nearby attractions such as St. Peters Basilica, Roman Forum and Pantheon. Don't just think about it — turn it into a reality! Book your perfect SantAngelo vacation with Expedia and experience travel your way.

The Latest Sant'Angelo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Maximus

Hotel Maximus

Rome City Centre
$1,386
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Rome (FCO)
9.2/10 Wonderful! (69 reviews)
U-Visionary Roma Hotel

U-Visionary Roma Hotel

Rome City Centre
Save 100% on your flight
$4,225
per person
Dec 26 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (511 reviews)
We stayed for a mother-daughter trip to celebrate my daughter’s 16th birthday, and the staff made it unforgettable. I arranged a birthday package, but they went above and beyond with flowers, cakes, champagne, fruit, chocolates, and balloons—including giant “16” balloons! My daughter was absolutely delighted. As a mother traveling alone with her daughter, safety was a concern, but we felt safe and comfortable throughout our stay. The central location is perfect, the restaurant is excellent, and breakfast was wonderful. Most of all, the staff were truly amazing—so kind and thoughtful. Highly recommended!

Reviewed on Oct 17, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$4,139
per person
Dec 26 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (1,011 reviews)
Hotel Delle Civette

Hotel Delle Civette

Nomentano
$1,774
per person
Dec 26 - Jan 1
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.6/10 Exceptional! (323 reviews)
The room was very clean and the staff was friendly and very helpful. I had very low expectations for the included breakfast but it was fantastic. Homemade baked goods every morning, breakfast sandwiches, scrambled eggs, bacon, fruit, different types of breads, cereal. We were always offered a cappuccino. It was great. It's a bit of a walk from the city center but it's very doable and the public transit system is great. I will stay here again the next time I'm in Rome.

Reviewed on Oct 19, 2026

Albergo Etico Roma

Albergo Etico Roma

Flaminio
$1,981
per person
Dec 24 - Dec 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.8/10 Exceptional! (379 reviews)
Gens très accueillant, un gros wow. Je recommande à 100%. Décoration de bon goût, grand confort il ne manque rien!

Reviewed on Oct 18, 2026

Where to stay in Sant'Angelo

Find the best Sant'Angelo areas and neighborhoods for the activities you enjoy most. Learn more about Sant'Angelo
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

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A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

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The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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Sant'Angelo Hotel Deals

Fabulous Village

Fabulous Village

Via Di Malafede 225 Rome RM
$68 nightly
$81 total
Oct 23 - Oct 24
Total with taxes and fees
8.2/10 Very Good! (1,912 reviews)
"Excepté le check-in Tout est bien"

Reviewed on Oct 17, 2026

Fabulous Village
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

Via Portuense, 2465 Fiumicino RM
Fully refundableReserve now, pay when you stay
$153 nightly
$179 total
Nov 18 - Nov 19
Total with taxes and fees
Best Western Hotel Rome Airport
Hotel Isola Sacra Rome Airport

Hotel Isola Sacra Rome Airport

Via Della Scafa 416 Fiumicino RM
Fully refundableReserve now, pay when you stay
$140 nightly
$165 total
Nov 18 - Nov 19
Total with taxes and fees
Hotel Isola Sacra Rome Airport
See all 16,606 properties in Sant'Angelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to go when
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Stay near popular Sant'Angelo attractions

Theatre of Marcellus

Find out about the history of Rome when you spend time at Theatre of Marcellus. Experience the acclaimed art scene and fascinating museums in this vibrant area.
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Great Synagogue of Rome

8.0/10 (4 reviews)
You can learn about the history of Rome with a visit to Great Synagogue of Rome. Visit the churches and notable monuments in this vibrant area.
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Portico di Ottavia

You can learn about the history of Rome when you stop by Portico di Ottavia. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Area Archeologica del Teatro di Marcello e del Portico d’Ottavia

Find out about the history of Rome when you take a trip to Area Archeologica del Teatro di Marcello e del Portico d’Ottavia. Experience the acclaimed theater scene and fascinating museums in this vibrant area.
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Fontana delle Tartarughe

Fontana delle Tartarughe is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? Visit the churches and notable monuments in this vibrant area.
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Museo Ebraico di Roma

You can find out about the history of Rome when you stop by Museo Ebraico di Roma. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
See properties

Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$130
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
Pasta-Making Class: Cook, Dine & Drink With A Local Chef

Pasta-Making Class: Cook, Dine & Drink With A Local Chef

$54
per adult
100% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.