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Check prices for these dates

Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29
In one month
Dec 11 - Dec 13
In two months
Jan 8 - Jan 10
No exact matches found, but these alternatives could be just right

Recommended hotels in Santa Cruz

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

1. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Equipetrol
9.4 out of 10, Exceptional, (159 reviews)
"Good location and value for money."
United States
Hui Hua
$36 nightly
The price is $36
Nov 25 - Nov 26
Ibis Santa Cruz DE LA Sierra
A multi-story hotel with a modern architectural design, featuring a prominent entrance with a red carpet and potted plants.

2. Lido Hotel

Lido Hotel
3.0 star property
Centro Histórico
9.2 out of 10, Wonderful, (57 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
$23 nightly
The price is $23
Nov 14 - Nov 15
Lido Hotel
A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

3. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Centro Histórico
9.2 out of 10, Wonderful, (140 reviews)
"Small but beautiful and very much in the center"
United States
Rajendra
$53 nightly
The price is $53
Dec 10 - Dec 11
Cosmopolitano Hotel Boutique
A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

4. Hotel Las Américas

Hotel Las Américas
3.0 star property
Centro Histórico
8.0 out of 10, Very good, (35 reviews)
"Very clean room and great staff"
Canada
Stanley
$21 nightly
The price is $21
Nov 10 - Nov 11
Hotel Las Américas
A multi-story building with a large glass facade, a visible storefront at the ground level, and a clear sky in the background.

5. 518 RENT

518 RENT
3.0 star property
Centro Histórico
$16 nightly
The price is $16
Nov 10 - Nov 11
518 RENT
A balcony with a glass railing, a view of greenery and buildings, and a clear sky.

6. HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (61 reviews)
"Clean room, good staff,"
United States
Neftali
$44 nightly
The price is $44
Nov 10 - Nov 11
HOTEL OSHO
A corridor with tiled flooring, potted plants, and a view of a building with a thatched roof.

7. Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
4.5 star property
Centro Histórico
$56 nightly
The price is $56
Nov 10 - Nov 11
Gran Hotel Santa Cruz
A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

8. Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (81 reviews)
"clean close to restaurants friendly staff shop nearby overall excellent place to stay"
United States
Luis
$47 nightly
The price is $47
Nov 14 - Nov 15
Chairú Eco Hotel
A balcony with a table set for breakfast, overlooking a swimming pool and a landscaped garden.

9. Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (419 reviews)
"The room and the bed, towels were very clean.The breakfast was very complete and very good."
Canada
Andre Leo
$99 nightly
The price is $99
Nov 24 - Nov 25
Sun Hotel
A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

10. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (261 reviews)
"Amazing hotel"
United States
Deivis
$119 nightly
The price is $119
Nov 30 - Dec 1
Marriott Santa Cruz de la Sierra Hotel
A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

11. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
$25 nightly
The price is $25
Nov 11 - Nov 12
Apart Hotel Premium Suites Santa Cruz
A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

12. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (293 reviews)
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
United States
Scott
$74 nightly
The price is $74
Nov 13 - Nov 14
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
A rooftop pool with lounge chairs and a cityscape view.

13. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
$39 nightly
The price is $39
Nov 20 - Nov 21
Premium Suites Deluxe Aparthotel Equipetrol
A multi-story hotel with balconies, air conditioning units, and a storefront with signage.

14. Gran Hotel Mediterráneo

Gran Hotel Mediterráneo
3.5 star property
Centro Histórico
10.0 out of 10, Exceptional, (1 review)
"Desde a recepção, a equipe da limpeza e o pessoal do café da manhã, foram sempre muito prestativos e disponíveis para ajudar no que foi necessário, voltaremos. A localização é bem próxima a praça central."
Brazil
Emerson
$49 nightly
The price is $49
Nov 10 - Nov 11
Gran Hotel Mediterráneo
A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

15. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (426 reviews)
"I love how nice and helpful staff was."
United States
Lizzie
$152 nightly
The price is $152
Nov 14 - Nov 15
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
A multi-story building with a sign for 'COMEDOR DOMINGO TAMISA III' indicating a hotel or lodging facility.

16. Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (3 reviews)
"A localização é ótima, a hospedagem se vc tiver sozinho tambem é ótima agora duas pessoas ja ficou apertado. O quarto é apertado os outros locais são ótimos"
Brazil
Paola
$19 nightly
The price is $19
Nov 10 - Nov 11
Mirador del Cielo
A modern bedroom with a bed, bedside table, and a desk with a laptop.

17. Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (112 reviews)
"Excelente Hotel "
Mexico
JACOB
$23 nightly
The price is $23
Dec 8 - Dec 9
Hotel G
A rooftop terrace with a hot tub, potted plants, and a view of buildings during sunset.

18. Sarao

Sarao
3.0 star property
Centro Histórico
$28 nightly
The price is $28
Nov 10 - Nov 11
Sarao
A hotel room with two beds, a desk, and a view of the city.

19. Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (102 reviews)
"Great location, nice and quiet neighborhood."
United States
ALEJANDRO
$48 nightly
The price is $48
Nov 23 - Nov 24
Delfines Collection Hotel By Mercure
A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

20. Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Equipetrol
8.2 out of 10, Very good, (214 reviews)
"Nice place to stay"
United States
Ricardo
$61 nightly
The price is $61
Dec 9 - Dec 10
Hotel LP Equipetrol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Top reviews in Santa Cruz

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.
Chairú Eco Hotel

Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz

10/10 Excellent

Nice and clean
United States
Brian
Reviewed October 28, 2026
Chairú Eco Hotel