Santa Cruz Vacations

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Your Santa Cruz Vacation

With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.

Find the Best Santa Cruz Vacation Packages

Things to do in Santa Cruz

Santa Cruz offers a vibrant mix of city-themed and cultural experiences perfect for families. Visitors can explore shopping centers and malls, unwind at resorts, and enjoy outdoor adventures like hiking and standup paddleboarding. For those looking for leisure, there's plenty of window shopping and long strolls to enjoy. Thrill-seekers can also find exciting roller coasters to experience, making Santa Cruz a well-rounded destination for all types of tourists.

Shopping

In Santa Cruz, visit Ventura Mall for a vibrant shopping experience with entertainment and family-friendly vibes. La Recova Artisan Walk offers a unique market atmosphere perfect for local crafts. If you're up for a drive, check out Patio Design LifeStyle Center for a stylish shopping environment.

Recreation

Experience the vibrant atmosphere at Ramon Tahuichi Aguilera Stadium, where you can enjoy local sports events. For a family-friendly outing, catch a movie at Cine Center. Don't miss the cultural richness at Casa Municipal de Cultura Raúl Otero Reiche, featuring captivating performances and artistic events.

Adventure

Parque Nacional Amboró offers thrilling hiking trails through diverse ecosystems, where you can spot unique wildlife. For adrenaline seekers, the nearby Chapare region features exhilarating white-water rafting experiences amidst stunning landscapes, perfect for adventure enthusiasts looking for an unforgettable experience.

Nightlife

In Santa Cruz, Bolivia, experience vibrant nightlife at Plaza 24 de Septiembre, filled with lively bars and clubs. Visit the trendy Equipetrol neighborhood for upscale lounges and dance the night away at popular venues like La Casa de la Cerveza and Club Level, where the energy is electric.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is perfect for city-themed and family vacations, offering rich cultural experiences. Explore popular attractions like the piazza, cathedral, and various landmarks that cater to diverse interests, including culture and outdoor activities. Don't miss out on discovering local gems and immersing yourself in the vibrant atmosphere of Santa Cruz for an unforgettable experience.

  • Plaza 24 de Septiembre: This vibrant square serves as the heart of Santa Cruz, where locals and visitors gather to enjoy cultural events, music, and lively street performances. Its lush gardens and historical significance make it a perfect spot to soak in the city's atmosphere and people-watch.
  • San Lorenzo Cathedral: A stunning example of colonial architecture, San Lorenzo Cathedral features intricate designs and a serene ambiance. Visitors can appreciate its artistic beauty and rich history while attending mass or exploring its peaceful surroundings.
  • Blacutt Square: Known for its unique excursions, Blacutt Square is a popular gathering place for locals and tourists alike. The square often hosts cultural fairs and events, offering a glimpse into the region's traditions and local crafts.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are slightly low and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly HighAverage
February77.0°F (25.0°C)Light RainMostly CloudyAverageAverage
March76.5°F (24.7°C)Light RainMostly SunnyAverageSlightly High
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnySlightly HighAverage
August72.9°F (22.7°C)No RainSunnyAverageSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnySlightly LowAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageSlightly Low
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowAverage

Tips to save on your trip to Santa Cruz

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santa Cruz.
  • Consider traveling during the off-peak season (typically June, August and November) for more affordable package holidays to Santa Cruz.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Santa Cruz Essential Information

Language
Spanish
Currency
Bolivian bolivianos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Viru Viru Intl. Airport (VVI)
Max Temp Winter
80ºF
Max Temp Summer
90ºF
Top Sights
Santa Cruz Zoo, San Lorenzo Cathedral and Sacred Art Museum

Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
9.4/10 Exceptional! (82 reviews)
Loved the fact we could check in early for a minimal fee. Staff were nice. The room was good but a bit stuffy and the air conditioning unit had a lot of dirt and dust in it. There was also a weird smell that they sprayed that was a bit nauseating. Otherwise the hotel had a great vibe and was decorated ...

Reviewed on 13 Jan, 2026

Ibis Santa Cruz DE LA Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
8.8/10 Excellent! (354 reviews)
Indeed this is a First Class hotel. Beautiful lobby, great dining area, beautiful pool, ample rooms.

Reviewed on 17 Jan, 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13 Santa Cruz Santa Cruz
8.2/10 Very Good! (334 reviews)
spotless

Reviewed on 9 Dec, 2025

Sun Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.