Title: Santa Cruz Vacation Packages 2026 | Expedia.com [Santa Cruz Travel Guide](https://expedia.com/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d6053940.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Cruz Vacations ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Santa Cruz Vacation With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like [Plaza 24 de Septiembre](https://www.expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction), [Guembe Biocenter](https://www.expedia.com/Guembe-Biocenter-Santa-Cruz.d553248621532465358.Vacation-Attraction) and [Ventura Mall](https://www.expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction). Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6053940) ### Discover the most popular places to visit in Santa Cruz ![Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people](https://images.trvl-media.com/place/6098828/2cbd296e-1bf4-483c-835b-4827ab9257d1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Plaza 24 de Septiembre 4.5/5(26 reviews) The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere. [](https://expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction) ![San Lorenzo Cathedral which includes heritage elements, heritage architecture and a church or cathedral](https://images.trvl-media.com/place/6098830/07633da9-6b86-46e4-8a7c-5cc7962f1701.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Lorenzo Cathedral 4.5/5(15 reviews) One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork. [](https://expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) #### Ventura Mall 4.5/5(28 reviews) During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area. [](https://expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction) ### What to do in Santa Cruz ![Fuerte de Samaipata, Bolivia](https://mediaim.expedia.com/localexpert/47039842/7ecefdd0-a146-4d89-9aae-e8e8d23d9dce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Samaipata Fort Tour: Ancient Ruins in 1 Full Day $315 per adult [](https://expedia.com/things-to-do/samaipata-fort-tour-ancient-ruins-in-1-full-day.a47039842.activity-details) ![The Che Guevara route is the most peculiar tourist destination in Bolivia.](https://mediaim.expedia.com/localexpert/47090379/4d80936c-4385-44e9-80b9-8e7660c32ae6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 4D/3N Expedition: Che Guevara Route - Disconnect from the World $799 per adult [](https://expedia.com/things-to-do/4d3n-expedition-che-guevara-route-disconnect-from-the-world.a47090379.activity-details) ![Trekking through the area of ​​​​the last armed struggle of Che Guevara.](https://mediaim.expedia.com/localexpert/47088323/cdf71877-c1dc-46c6-8af1-3b0ab483f139.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 3D/2N Getaway on the Che Guevara Route Live the Adventure! $699 per adult [](https://expedia.com/things-to-do/3d2n-getaway-on-the-che-guevara-route-live-the-adventure.a47088323.activity-details) [See all activities in Santa Cruz](https://expedia.com/things-to-do/search?rid=6053940) ## Santa Cruz Hotel Deals ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ibis Santa Cruz DE LA Sierra AVENIDA CRISTOBAL DE MENDOZA Santa Cruz $49 nightly $49 total Feb 27 - Feb 28 9.6/10 Exceptional! (90 reviews) Great value Reviewed on Feb 21, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F27%2F2026&endDate=2%2F28%2F2026&selected=87138613&PinnedHotelID=87138613&HadPinnedHotel=true®ionId=6053940) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Camino Real Hotel Av. San Martín y 4to. Anillo Santa Cruz $121 nightly $121 total Mar 1 - Mar 2 9/10 Wonderful! (420 reviews) Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options. Reviewed on Feb 5, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=444475&PinnedHotelID=444475&HadPinnedHotel=true®ionId=6053940) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel Ave. San Martin, #455 Santa Cruz $136 nightly $136 total Mar 27 - Mar 28 9/10 Wonderful! (362 reviews) Lovely staff. Great buffets. Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F27%2F2026&endDate=3%2F28%2F2026&selected=18758&PinnedHotelID=18758&HadPinnedHotel=true®ionId=6053940) [See all 292 properties in Santa Cruz](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F26%2F2026&endDate=2%2F27%2F2026®ionId=6053940) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Santa Cruz Vacation Packages ### Things to do in Santa Cruz Santa Cruz offers a vibrant mix of city-themed and cultural experiences perfect for families. Visitors can explore shopping centers and malls, unwind at resorts, and enjoy outdoor adventures like hiking and standup paddleboarding. For those looking for leisure, there's plenty of window shopping and long strolls to enjoy. Thrill-seekers can also find exciting roller coasters to experience, making Santa Cruz a well-rounded destination for all types of tourists. **Shopping** In Santa Cruz, visit [Ventura Mall](https://www.expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction) for a vibrant shopping experience with entertainment and family-friendly vibes. [La Recova Artisan Walk](https://www.expedia.com/La-Recova-Artisan-Walk-Santa-Cruz.d553248621532371683.Vacation-Attraction) offers a unique market atmosphere perfect for local crafts. If you're up for a drive, check out [Patio Design LifeStyle Center](https://www.expedia.com/Patio-Design-LifeStyle-Center-Santa-Cruz.d916427946376515584.Vacation-Attraction) for a stylish shopping environment. **Recreation** Experience the vibrant atmosphere at [Ramon Tahuichi Aguilera Stadium](https://www.expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction), where you can enjoy local sports events. For a family-friendly outing, catch a movie at [Cine Center](https://www.expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction). Don't miss the cultural richness at Casa Municipal de Cultura Raúl Otero Reiche, featuring captivating performances and artistic events. **Adventure** Parque Nacional Amboró offers thrilling hiking trails through diverse ecosystems, where you can spot unique wildlife. For adrenaline seekers, the nearby Chapare region features exhilarating white-water rafting experiences amidst stunning landscapes, perfect for adventure enthusiasts looking for an unforgettable experience. **Nightlife** In Santa Cruz, Bolivia, experience vibrant nightlife at Plaza 24 de Septiembre, filled with lively bars and clubs. Visit the trendy Equipetrol neighborhood for upscale lounges and dance the night away at popular venues like La Casa de la Cerveza and Club Level, where the energy is electric. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Find the best attractions in Santa Cruz Santa Cruz, Bolivia, is perfect for city-themed and family vacations, offering rich cultural experiences. Explore popular attractions like the piazza, cathedral, and various landmarks that cater to diverse interests, including culture and outdoor activities. Don't miss out on discovering local gems and immersing yourself in the vibrant atmosphere of Santa Cruz for an unforgettable experience. - **[Plaza 24 de Septiembre: ](https://www.expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction)** This vibrant square serves as the heart of Santa Cruz, where locals and visitors gather to enjoy cultural events, music, and lively street performances. Its lush gardens and historical significance make it a perfect spot to soak in the city's atmosphere and people-watch. - **[San Lorenzo Cathedral: ](https://www.expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction)** A stunning example of colonial architecture, San Lorenzo Cathedral features intricate designs and a serene ambiance. Visitors can appreciate its artistic beauty and rich history while attending mass or exploring its peaceful surroundings. - **[Blacutt Square: ](https://www.expedia.com/Blacutt-Square-Santa-Cruz.d6126767.Vacation-Attraction)** Known for its unique excursions, Blacutt Square is a popular gathering place for locals and tourists alike. The square often hosts cultural fairs and events, offering a glimpse into the region's traditions and local crafts. ### Best time to go to Santa Cruz The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are slightly low and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 78.3°F (25.7°C) | Light Rain | Mostly Sunny | Slightly High | Average | | February | 77.0°F (25.0°C) | Light Rain | Mostly Cloudy | Average | Average | | March | 76.5°F (24.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | April | 74.5°F (23.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 70.2°F (21.2°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | June | 67.8°F (19.9°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | July | 68.5°F (20.3°C) | No Rain | Mostly Sunny | Slightly High | Average | | August | 72.9°F (22.7°C) | No Rain | Sunny | Average | Slightly Low | | September | 77.9°F (25.5°C) | Light Rain | Sunny | Slightly High | Slightly High | | October | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | November | 79.3°F (26.3°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Slightly Low | Average | ### Tips to save on your trip to Santa Cruz - Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santa Cruz. - Consider traveling during the off-peak season (typically June, August and November) for more affordable package holidays to Santa Cruz. - Use the *Price per traveler* filter on Expedia to find a package deal that suits your budget. - Check the *VIP Access properties* filter to discover outstanding hotels with added member perks at select properties. ## Santa Cruz Essential Information | Language | Spanish | | --------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Bolivian bolivianos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Viru Viru Intl. Airport (VVI) | | Max Temp Winter | 80ºF | | Max Temp Summer | 90ºF | | Top Sights | [Santa Cruz Zoo](https://www.expedia.com/Santa-Cruz-Zoo-Santa-Cruz.d6098836.Vacation-Attraction), [San Lorenzo Cathedral](https://www.expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) and [Sacred Art Museum](https://www.expedia.com/Sacred-Art-Museum-Santa-Cruz.d553248621563217782.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) 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[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Santa Cruz vacation package cost? ### What are the cheapest months to go to Santa Cruz? ### How many days is enough for Santa Cruz? ### Is it worth booking a vacation package to Santa Cruz? ### How to find the best Santa Cruz package deals? ### Is it cheaper to book a Santa Cruz vacation as a package? ### When to book a vacation package to Santa Cruz? ### How to plan a trip to Santa Cruz? > 1. Choose your travel dates: What you plan to do in Santa Cruz and your preferred season can help you decide when to go. > 2. Calculate your budget: Ensure you have enough money to pay for everything from transportation and dining out to airfares and activities. Your hotel will likely be the largest expense during your trip to Santa Cruz. > 3. Discover Santa Cruz using Expedia's [trip planning tool](https://www.expedia.com/why/trip-planning): Gain insights into the leading attractions and best stays for your trip to Santa Cruz. You can also save your favorite places, collaborate with family and friends and manage all your plans in one place. > 4. Decide how long to go for: Now that you're more familiar with Santa Cruz, you can work out the ideal length of your break. Create a rough plan and allocate enough time to cover everything you want to see. > 5. Bundle your accommodations and airfare: Once you've nailed down your dates and duration, lock in the ideal Santa Cruz vacation package for you. > 6. Book experiences or activities in advance: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on the highlights of Santa Cruz. Find all the incredible [things to do in Santa Cruz](https://www.expedia.com/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities) with our dedicated travel guide. ### Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Vacation Rentals - [Historic Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Historic-Hotel.0-0-d6297178-tHistoricHotel.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Spa-Hotel.0-0-d6297178-tSpaHotel.Hotel-Filter-Destinations) - [Family Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Family-Hotel.0-0-d6297178-tFamilyHotel.Hotel-Filter-Destinations) - [Hotel Wedding Venues Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Wedding-Hotels.0-0-d6297178-tWeddingHotels.Hotel-Filter-Destinations) - [Casino Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Casino-Hotel.0-0-d6297178-tCasinoHotel.Hotel-Filter-Destinations) - [Santa Cruz Hotels ](https://www.expedia.com/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations) - [Pet-Friendly Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Pet-Friendly-Hotel.0-0-d6297178-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Hotels with Hot Tubs in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Hot-Tubs.0-0-d6297178-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Cheap Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Cheap-Hotels.0-0-d6297178-tCheapHotels.Hotel-Filter-Destinations) - [Beach Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Beach-Hotel.0-0-d6297178-tBeachHotel.Hotel-Filter-Destinations) - [Golf Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Golf-Hotel.0-0-d6297178-tGolfHotel.Hotel-Filter-Destinations) - [Romantic Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Romantic-Hotel.0-0-d6297178-tRomanticHotel.Hotel-Filter-Destinations) - [Hotels with Waterslides in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Waterslides.0-0-d6297178-tHotelswithWaterslides.Hotel-Filter-Destinations) - [Honeymoon Resorts & in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Honeymoon-Hotels.0-0-d6297178-tHoneymoonHotels.Hotel-Filter-Destinations) - [Hotels near Plaza 24 de Septiembre ](https://www.expedia.com/Plaza-24-De-Septiembre-Hotels.0-l6098828-0.Travel-Guide-Filter-Hotels) - [Hotels near Artecampo ](https://www.expedia.com/Artecampo-Hotels.0-l553248621532371681-0.Travel-Guide-Filter-Hotels) - [Hotels near Ramon Tahuichi Aguilera Stadium ](https://www.expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Hotels.0-l6098832-0.Travel-Guide-Filter-Hotels) - [Hotels near Cine Center ](https://www.expedia.com/Cine-Center-Hotels.0-l6126769-0.Travel-Guide-Filter-Hotels) - [Flights to Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations) - [Flights from San Diego (SAN) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/san/srz/san-diego-to-santa-cruz) - 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