Santa Cruz Vacation Packages 2026 from $1,114

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Your Santa Cruz Vacation

With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.

The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel LP Equipetrol

$1,114

per person

Aug 23 - Aug 30

found 24 hours ago

Roundtrip non-stop flight included

New York (NYC) to Santa Cruz (VVI)

8.2/10 Very Good! (210 reviews)

El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz

Reviewed on Jul 14, 2026

Camino Real Hotel

$1,282

per person

Aug 23 - Aug 30

found 24 hours ago

Roundtrip non-stop flight included

New York (NYC) to Santa Cruz (VVI)

9/10 Wonderful! (433 reviews)

Wonderful place to stay while visiting Santa Cruz Bolivia.

Reviewed on Jul 7, 2026

Swissôtel Santa Cruz De La Sierra

$1,229

per person

Aug 23 - Aug 30

found 24 hours ago

Roundtrip non-stop flight included

New York (NYC) to Santa Cruz (VVI)

9.2/10 Wonderful! (88 reviews)

Hospedagem muito boa, hotel limpo e bem cuidado, café da manhã bom, funcionários atenciosos e prestativos. Recomendo.

Reviewed on Jul 13, 2026

Alfonsina Hotel Boutique by Inboccaluppo

$1,247

per person

Aug 23 - Aug 30

found 24 hours ago

Roundtrip non-stop flight included

New York (NYC) to Santa Cruz (VVI)

9.4/10 Exceptional! (45 reviews)

Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars

Reviewed on Jul 6, 2026

Hotel Cortez

$1,217

per person

Aug 23 - Aug 30

found 24 hours ago

Roundtrip non-stop flight included

New York (NYC) to Santa Cruz (VVI)

9.2/10 Wonderful! (145 reviews)

Very good.

Reviewed on Jul 14, 2026

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Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.

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