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Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Jul 24 - Jul 26
In two months
Sep 4 - Sep 6
In three months
Oct 2 - Oct 4
In four months
Oct 30 - Nov 1

Our top choices for Santa Cruz vacation rentals

1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
$107 nightly
The price is $107
Jul 22 - Jul 23
Shabbat Hotel Boutique
Terrace/patio

Encanto Verde

Encanto Verde
2.5 star property
Marinilla
$50 nightly
The price is $50
Jul 9 - Jul 10
Encanto Verde
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Increíble view.. comfortable clean!! "
United States
Hector
$59 nightly
The price is $59
Jul 9 - Jul 10
Skyline Ecoliving
Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
9.6 out of 10, Exceptional, (7 reviews)
"Perfect property ! Big enough. Big fridge, full kitchen; excellent bathroom and bed. The whole room is full little details and excellent design!"
United States
Jorge
$75 nightly
The price is $75
Jul 11 - Jul 12
Mali Experience
Standard Room, Patio, Mountain View | Outdoor dining

Hotel Boutique Almaia 17 Near the Airport

Hotel Boutique Almaia 17 Near the Airport
3.0 star property
Rionegro
$118 nightly
The price is $118
Jul 19 - Jul 20
Hotel Boutique Almaia 17 Near the Airport
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.2 out of 10, Very Good, (62 reviews)
"I liked everything, surrounded by incredible nature green hills, river and the wild sound."
United States
Alberto
$67 nightly
The price is $67
Jul 13 - Jul 14
PORTANOVA SUITES by ADVENTU
Indoor pool

Casa Los Curazaos

Casa Los Curazaos
3.5 star property
Rionegro
8.0 out of 10, Very Good, (1 review)
"Hermosa cabaña, a tan solo 1km de la via que conduce de LLanogrande a la Ceja. Sobria, bien decorada, con todo lo necesario para una corta estadia. "
Mexico
CARLOS
$162 nightly
The price is $162
Jul 8 - Jul 9
Casa Los Curazaos
Romantic Bungalow, Mountain View | Premium bedding, down comforters, individually decorated

Ancestral Glamping

Ancestral Glamping
2.0 star property
Barbosa
$142 nightly
The price is $142
Jul 20 - Jul 21
Ancestral Glamping
Studio | View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (476 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
$81 nightly
The price is $81
Jul 20 - Jul 21
Travelers Rio Verde Living Suites
Front of property

Nomadic Boutique Living and Experience Center

Nomadic Boutique Living and Experience Center
4.0 star property
El Poblado
10.0 out of 10, Exceptional, (11 reviews)
"Good property and the area looks safe."
Canada
Josue
$62 nightly
The price is $62
Jul 14 - Jul 15
Nomadic Boutique Living and Experience Center
Deluxe Cabin, Balcony, Mountain View

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
$91 nightly
The price is $91
Jul 9 - Jul 10
Onirico Luxury
Deluxe Apartment, Balcony, Mountain View | Blackout drapes, free WiFi

A Estadia tranquila con vista al bosque

A Estadia tranquila con vista al bosque
2.5 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Todo como lo esperado, volvería."
Colombia
Gustavo Adolfo
$79 nightly
The price is $79
Jul 8 - Jul 9
A Estadia tranquila con vista al bosque
Meeting facility

Casa Hotel Fiba Magueza

Casa Hotel Fiba Magueza
4.5 star property
Guarne
$75 nightly
The price is $75
Jul 20 - Jul 21
Casa Hotel Fiba Magueza
Deluxe Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | 1 bedroom, premium bedding, down comforters, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (280 reviews)
"The best!"
United States
Samuel
$65 nightly
The price is $65
Jul 11 - Jul 12
Portal del Rodeo ApartaHotel - Arkadia Mall
Lobby

Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (703 reviews)
"The reception staff were great hosts, the room was as advertised. A nice hotel and good location"
United States
Neil
$90 nightly
The price is $90
Jul 8 - Jul 9
Haven, A Design Hotel
Reception

Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
9.2 out of 10, Wonderful, (68 reviews)
"Staff was very polite, location was perfect… very close to amazing tourism spots! "
United States
Patricia
$70 nightly
The price is $70
Jul 9 - Jul 10
Metropolitan Living by HOUSY
Coffee shop

B 48 Living by B Rent

B 48 Living by B Rent
4.0 star property
Laureles - Estadio
9.6 out of 10, Exceptional, (20 reviews)
"I love the people & I love the area. One of the best place to stay in Medellin. "
United States
Lusene
$50 nightly
The price is $50
Jul 9 - Jul 10
B 48 Living by B Rent
Interior

Vista Hotel Medellin

Vista Hotel Medellin
4.0 star property
Medellín
$133 nightly
The price is $133
Jul 11 - Jul 12
Vista Hotel Medellin
Deluxe Suite, City View | Desk, laptop workspace, free WiFi

ONCE SUITES

ONCE SUITES
2.5 star property
Envigado
$44 nightly
The price is $44
Jul 27 - Jul 28
ONCE SUITES
Luxury Studio | In-room safe, desk, laptop workspace, soundproofing

Go Living and Suites by Jalo

Go Living and Suites by Jalo
3.0 star property
El Poblado
9.2 out of 10, Wonderful, (122 reviews)
"The mountain view was beautiful "
United States
Allison
$54 nightly
The price is $54
Jul 21 - Jul 22
Go Living and Suites by Jalo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Heiss Hotel By Jalo

Heiss Hotel By Jalo

10/10 Excellent
"Todo muy bonito los cuartos cómodos y la limpieza excelente, cerca del poblado"
Tamia 7-night trip
Posted 6 hours ago
Heiss Hotel By Jalo

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $29 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxury Home In Las Lomas: You might want to consider this Santa Cruz vacation home rental for your stay. It is equipped with an outdoor pool, air-conditioning, and free WiFi to help you feel comfortable during your stay. It has 6 bedrooms as well as a kitchen with a full-sized fridge, a microwave, and a coffee maker, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Lleras Park. In the larger area, you’ll find Santafé Mall and Medellin Botanical Garden.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.