Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
May 1 - May 3
In two months
Jun 12 - Jun 14
In three months
Jul 10 - Jul 12
In four months
Aug 7 - Aug 9

Our top choices for Santa Cruz vacation rentals

Interior

Casagrande

Casagrande
2.0 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Very nice large room with king size bed, very low noise beautiful Mountain View’s. It was a little cold for pool but, various shopping centers close to property and public transport passes right in front. Awesome place to stay."
United States
Alex
$49 nightly
The price is $49
Apr 19 - Apr 20
Casagrande
Deluxe Apartment, Garden View | Desk, laptop workspace, blackout drapes, soundproofing

Edificio Cielo Verde

Edificio Cielo Verde
3.0 star property
Rionegro
$171 nightly
The price is $171
Apr 14 - Apr 15
Edificio Cielo Verde
Exterior

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
$117 nightly
The price is $117
Apr 14 - Apr 15
Candelaria Campestre
Deluxe Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | 1 bedroom, premium bedding, down comforters, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (271 reviews)
"the staff was very friendly good food and the room is so nice highly recomended"
United States
Astrid
$65 nightly
The price is $65
Apr 21 - Apr 22
Portal del Rodeo ApartaHotel - Arkadia Mall
Studio | View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
$72 nightly
The price is $72
Apr 14 - Apr 15
Travelers Rio Verde Living Suites
Suite (302) | Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (2 reviews)
"My room was a well-equipped luxury studio apartment that included a washer/dryer (what a treat) and a great small kitchen and a large walk-in shower. Absolutely loved my accommodation. And for you gringos and gringas out there with shaky Spanish, your host, Juan, not only speaks impeccable English but is so very helpful. Highly recommend!"
United States
Gabrielle
$75 nightly
The price is $75
Apr 14 - Apr 15
Mali Experience
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Super impressive mountain view directly visible as soon as you open your eyes in the morning. "
United States
Antranik
$72 nightly
The price is $72
Apr 20 - Apr 21
Skyline Ecoliving
1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
$120 nightly
The price is $120
Apr 14 - Apr 15
Shabbat Hotel Boutique
Lobby

Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (680 reviews)
"Was reallly good excellent locations"
United States
Alvaro
$93 nightly
The price is $93
Apr 14 - Apr 15
Haven, A Design Hotel
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (60 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
$99 nightly
The price is $99
Apr 14 - Apr 15
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Standard Room, Patio, Mountain View | Outdoor dining

Almaia 17

Almaia 17
3.0 star property
Rionegro
$123 nightly
The price is $123
Apr 14 - Apr 15
Almaia 17
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.4 out of 10, Very Good, (51 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
$59 nightly
The price is $59
Apr 29 - Apr 30
PORTANOVA SUITES by ADVENTU
Front of property

Seissta Medellin

Seissta Medellin
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (236 reviews)
"Excellent modern facility"
United States
keith
$108 nightly
The price is $108
May 12 - May 13
Seissta Medellin
Reception

Sites Hotel

Sites Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,143 reviews)
"Everything was great, and the staff were so helpful and nice all the time, will definitely be back. "
United States
Romulo
$75 nightly
The price is $75
Apr 21 - Apr 22
Sites Hotel
Villa | Pool | Outdoor pool

Luxury Villa In Provenza

Luxury Villa In Provenza
4.0 star property
El Poblado
$1,020 nightly
The price is $1,020
Apr 14 - Apr 15
Luxury Villa In Provenza
Premium Cabin | Minibar, individually decorated, individually furnished, free WiFi

Wasikuna cabañas rurales tipo glamping

Wasikuna cabañas rurales tipo glamping
3.0 star property
Guarne
9.2 out of 10, Wonderful, (5 reviews)
"Nice place "
United States
GERARDO
$159 nightly
The price is $159
Apr 14 - Apr 15
Wasikuna cabañas rurales tipo glamping
Deluxe Cabin, Balcony, Mountain View

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
$85 nightly
The price is $85
Apr 23 - Apr 24
Onirico Luxury
Reception

Praia Apartaestudios

Praia Apartaestudios
4.5 star property
Sabaneta
8.0 out of 10, Very Good, (15 reviews)
"It nice and comfortable. "
United States
DENIS
$40 nightly
The price is $40
Apr 14 - Apr 15
Praia Apartaestudios
Deluxe Apartment | Living area | 43-inch Smart TV with satellite channels, TV

Alcázar de Oviedo By EE Hotels

Alcázar de Oviedo By EE Hotels
3.0 star property
El Poblado
9.4 out of 10, Exceptional, (169 reviews)
"Love it, been here for my second time and will choose it again"
United States
Annelies
$92 nightly
The price is $92
Apr 19 - Apr 20
Alcázar de Oviedo By EE Hotels
Room

hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
10.0 out of 10, Exceptional, (1 review)
"Hotel in a good location, comfortable and has a great staff."
United States
Valencia
$21 nightly
The price is $21
Apr 17 - Apr 18
hotel civitas medellin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"Todo muy bonito y limpio, pero demasiado ruidoso el ambiente."
Myritza Fernandez 3-night trip
Posted 3 hours ago
Calle Flora Hotel by Jalo

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $30 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

8 BR Luxury 6000 S.F. Mansion , 2 Bars Hot Tub, Bbq and Ac : Visitors like this Santa Cruz vacation home rental. It offers a patio, a pool table, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 9 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a hot tub.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find University of Antioquia and Arvi Park.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.