Santa Isabel Cholula Vacations from $275

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • Better together

    Save up to $1,045 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Isabel Cholula Vacation

The rich history and welcoming locals are just the start of the things Santa Isabel Cholula has on offer. Enjoy the sights and sounds of this lively city your way with a customized Santa Isabel Cholula vacation package. If a sightseeing tour is on the cards during your trip to Santa Isabel Cholula, look around leading attractions like Atlixco Square, Templo San Francisco Acatepec and Convento de San Francisco. Stop daydreaming and start adventuring. Browse the multitude of options on Expedia today and put your Santa Isabel Cholula vacation plans into motion!

The Latest Santa Isabel Cholula vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Nube, Puebla Centro

Hotel Nube, Puebla Centro

3.5 out of 5
Puebla Historic Center
Price was $382, price is now $275 per person
$275
per person
Dec 2 - Dec 8
found 1 day ago
Roundtrip flight included
Monterrey (MTY) to Puebla (PBC)
9.4/10 Exceptional! (190 reviews)
Very clean and convenient to walk and easy to get to places

Reviewed on Aug 19, 2025

Collection O Al otro lado del rio, Puebla

Collection O Al otro lado del rio, Puebla

3 out of 5
Puebla Historic Center
Save 100% on your flight
Price was $518, price is now $296 per person
$296
per person
Dec 2 - Dec 8
found 1 day ago
Roundtrip flight included
Monterrey (MTY) to Puebla (PBC)
9/10 Wonderful! (195 reviews)
Not great for holiday, just fine for quick stay. Parking is not in the property, it is close but it is need it to the staff to open the gate, at night is not ideal. Hotel have several not hotel restaurantes inside the hotel and they are too loud. Again, not for holiday only for quick stay.

Reviewed on Oct 14, 2025

Hotel Andante

Hotel Andante

3.5 out of 5
Puebla Historic Center
Price was $579, price is now $375 per person
$375
per person
Jan 1 - Jan 5
found 1 day ago
Roundtrip flight included
Monterrey (MTY) to Puebla (PBC)
9.2/10 Wonderful! (246 reviews)
Cleanliness great staff

Reviewed on Oct 10, 2025

Xoxula by Inmense

Xoxula by Inmense

4 out of 5
Cholula
Price was $743, price is now $540 per person
$540
per person
Nov 27 - Dec 1
found 1 day ago
Roundtrip non-stop flight included
Houston (HOU) to Puebla (PBC)
9/10 Wonderful! (182 reviews)
Very nice hotel, good beds and the restaurant had a lovely breakfast. I would stay here again!

Reviewed on Jan 8, 2025

Hotel Boutique Casareyna

Hotel Boutique Casareyna

4.5 out of 5
Puebla Historic Center
Save 100% on your flight
Price was $598, price is now $436 per person
$436
per person
Dec 2 - Dec 8
found 1 day ago
Roundtrip flight included
Monterrey (MTY) to Puebla (PBC)
9.6/10 Exceptional! (1,007 reviews)
Really nice stay--helpful staff (patient with our beginner Spanish), excellent restaurants, and terrific rooms (our family had two different but equally nice rooms). Easy walk to the historic city center with lots to do. We'd have liked better wifi service, but other than that, we loved it. We'll be back!

Reviewed on Oct 18, 2025

Don't see what you're looking for?
See all available trips from Columbus to Santa Isabel Cholula
View all trips

Discover the most popular places to visit in Santa Isabel Cholula

Africam Safari showing land animals and zoo animals

Africam Safari

4.5/5(31 reviews)

Bring the whole family for an entertaining day out. In the car or on foot, spot lions, giraffes, elephants and more roaming together.

Africam Safari
Zocalo Square featuring heritage elements

Zócalo de Puebla

4.5/5(188 reviews)

View the public works of art, relax in one of the cafés and get a sense of the culture in this central plaza.

Zócalo de Puebla
Puebla Cathedral which includes night scenes, heritage architecture and a church or cathedral

Puebla Cathedral

5/5(196 reviews)

Listen to the choral performances and appreciate the excellent acoustics of this iconic church. Marvel at the octagonal altar, among other treasures.

Puebla Cathedral

What to do in Santa Isabel Cholula

Elephants at the African Safari Zoo in Puebla

Africam Safari Park

$29
per adult
88% of travellers recommend
Africam Safari Park
Turitour Discover Cholula and Atlixco Magical Towns

Discover Cholula and Atlixco Magical Towns

$37
per adult
Discover Cholula and Atlixco Magical Towns
Puebla: Walking Tour of Puebla City

Puebla: Walking Tour of Puebla City

$35
per adult
Puebla: Walking Tour of Puebla City
See all activities in Santa Isabel Cholula

Santa Isabel Cholula Hotel Deals

NH Puebla Centro Histórico

NH Puebla Centro Histórico

4 out of 5
Calle 5 Sur #105, Col. Centro, Puebla, PUE
Fully refundable
$55 nightly
The price is $66 total per night from Nov 9 to Nov 10
$66 total
Nov 9 - Nov 10
Total with taxes and fees
8.6/10 Excellent! (1,448 reviews)
The place is very well located, comfortable, good breakfast, but the lobby looks a bit unattended, the lobby lady's room was dirty (3 toilets and all dirty).

Reviewed on Oct 20, 2025

NH Puebla Centro Histórico
Camino Real Puebla Angelopolis

Camino Real Puebla Angelopolis

4 out of 5
Boulevard Atlixcayotl Km 5, Fraccionamiento La Vista, San Andrés Cholula, PUE
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $71 total per night from Nov 4 to Nov 5
$71 total
Nov 4 - Nov 5
Total with taxes and fees
8/10 Very Good! (1,986 reviews)
+

Reviewed on Oct 9, 2025

Camino Real Puebla Angelopolis
Holiday Inn Express Puebla by IHG

Holiday Inn Express Puebla by IHG

3.5 out of 5
Blvd. Hermanos Serdan 45, Colonia Amor, Puebla, PUE
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $68 total per night from Nov 2 to Nov 3
$68 total
Nov 2 - Nov 3
Total with taxes and fees
9.4/10 Exceptional! (1,573 reviews)
The lobster was good

Reviewed on Oct 3, 2025

Holiday Inn Express Puebla by IHG
See all 600 properties in Santa Isabel Cholula
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Cholula Vacation Packages

Santa Isabel Cholula Essential Information

Language
Spanish
Currency
Mexican pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Hermanos Serdan Intl. Airport (PBC)
Population
1,900
Top Sights
Estrella de Puebla Observation Wheel, Cuexcomate Volcano and International Baroque Museum

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Santa Isabel Cholula vacation package cost?
You'll find cheap prices from $275 on Expedia for your Santa Isabel Cholula break. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santa Isabel Cholula costs.
What are the cheapest months to go to Santa Isabel Cholula?
January, February and June are great times to look for cheap Santa Isabel Cholula vacation packages. Traveling in less busy months means you can typically find lower prices on flights and hotels.
How many days is enough for Santa Isabel Cholula?
Usually, a handful of days is enough to explore the top attractions during your Santa Isabel Cholula vacation. But if you want to have more time to rest or go on day tours, consider extending your trip.
How to find the best Santa Isabel Cholula package deals?
Finding a cheap Santa Isabel Cholula package deal is a cinch with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a couple of filters and see what's available. You can personalize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most economical Santa Isabel Cholula package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santa Isabel Cholula vacation as a package?
You can enjoy significant savings on your next Santa Isabel Cholula retreat by booking a customized vacation package. Click on the "Package" heading, then select your destination and travel dates to view the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Santa Isabel Cholula?
Enjoy incredible discounts by booking your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for an impromptu Santa Isabel Cholula escape.
How to plan a trip to Santa Isabel Cholula?

  1. Choose when to go: Check your diary and pack your bags. Your favorite time of year and the type of activities on offer will also help you decide when to visit Santa Isabel Cholula.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and dining out to activities and flights. Your hotel will likely be the largest expense during your trip to Santa Isabel Cholula.
  3. Organize your Santa Isabel Cholula getaway with Expedia's trip planning tool: Look for and book accommodations and experiences all in one place. You can also collaborate with your group to plan an unforgettable trip to Santa Isabel Cholula together.
  4. Work out your trip length: Think about how much time you want to spend exploring Santa Isabel Cholula. Plan your itinerary so you can get to all the attractions and experiences you're interested in at a comfortable pace.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Santa Isabel Cholula vacation package.
  6. Add on experiences and excursions: Have a look at our dedicated travel guide to find some incredible things to do in Santa Isabel Cholula, Puebla (and vicinity). Book tickets or make reservations in advance to save time and avoid the stress of trying to find activities when you arrive.

Does Expedia offer Book Now, Pay Later Santa Isabel Cholula vacation packages?
Secure your perfect trip to Santa Isabel Cholula with help from Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or wait for the next payday — we've teamed up with online lender Affirm to offer you flexibility with your finances. Our vacation packages with payment plans let you split the cost over 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to budget for your trip and snap up cheap deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.