Top 10 Hotels in Santa Isabel Cholula (from $24) 2026 - Competitive Prices

Go beyond your typical stay in Santa Isabel Cholula

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Our top choices for Santa Isabel Cholula hotels

A large, historic building with a dome and multiple towers, surrounded by well-maintained gardens and palm trees.

A bedroom with a stone wall, wooden beams, a bed with pillows, a chandelier, and a window with curtains.

A well-maintained outdoor area with a swimming pool, palm trees, and a historic building with a dome.

A bedroom with a large bed, a wooden ceiling, a stone wall, and a view of the outdoors.

1. Hacienda Santo Cristo Hotel & Spa - Adults Only

Atlixco

Mati

$87 nightly

$104 total

Nov 19 - Nov 20

Total with taxes and fees

A dining area with wooden tables and chairs, a rustic stone wall, and decorative plants.

A swimming pool with thatched-roof structures, surrounded by greenery.

A compact hotel room with a bed, a small desk, a kitchenette, and a built-in air conditioning unit.

A dining table set with wine glasses, cutlery, and decorative foliage.

2. BV Hotel Atlixco

Atlixco

Lori

$82 nightly

$97 total

Oct 21 - Oct 22

Total with taxes and fees

An indoor atrium with a central staircase, potted plants, and a hanging light fixture.

A multi-level atrium with terracotta planters, arched ceilings, and hanging lights.

A staircase with a wooden floor leading up to a landing with a potted plant.

A modern hotel room with a wooden desk, a flat-screen TV, a blue chair, a sofa, and a decorative wall panel.

3. Hotel Casa de la Audiencia

Atlixco

Jorge

$106 nightly

$128 total

Nov 19 - Nov 20

Total with taxes and fees

A courtyard with a central lawn, surrounded by buildings with a modern architectural style, featuring large windows and a prominent tree in the background.

A modern building with a covered walkway, large windows, and a well-maintained garden.

A swimming pool surrounded by a stone wall with plants.

A corridor with a stone wall on one side and a blue wall on the other, with a tiled floor and recessed lighting.

4. Soleil Inn Atlixco

Atlixco

Maria

$60 nightly

$72 total

Nov 20 - Nov 21

Total with taxes and fees

A modern lobby with a reception desk, two seating areas, and a large abstract painting on the wall.

A modern interior with three chairs, a large abstract painting, and a view of the city through sheer curtains.

A multi-story building with a sign for 'Yoga Shala Casa Utpal'.

A modern lobby with a reception desk, seating area, and a decorative wall.

5. Kharma Suites

San Andrés Cholula

Jacob

$44 nightly

$53 total

Oct 21 - Oct 22

Total with taxes and fees

A swimming pool with a tiled floor, lounge chairs, and umbrellas.

A modern reception area with a curved white reception desk, a black leather sofa, and a large window with a view of palm trees.

A rooftop terrace with a modern outdoor seating area, including a sofa and a glass coffee table.

A hotel room with a large bed, two bedside tables, a chair, and a view of the city through sheer curtains.

6. Sonata Hotel

Lomas de Angelópolis

Epifania

$62 nightly

$74 total

Oct 22 - Oct 23

Total with taxes and fees

An outdoor seating area with tables and chairs, large windows, and potted plants.

A modern bar area with a counter, bar stools, and shelves stocked with bottles.

A modern conference room with a long table, teal upholstered chairs, and pendant lighting.

A reception area with a wooden reception desk, a large blue and white vase, and a sign that reads "bienvenido a Hampton welcome".

7. Hampton Inn & Suites by Hilton Puebla

Tlaxcalancingo

Fausto

$62 nightly

$74 total

Oct 25 - Oct 26

Total with taxes and fees

A hot tub with a wooden deck, surrounded by a pool, and a grassy area with a building in the background.

A modern outdoor pool area with a tiled deck, a covered seating area, and a view of the surrounding landscape.

A hotel room with a bed, a bedside table with a cup, a spoon, and a book. There is a TV mounted on the wall and a microwave in the kitchen area.

A hotel reception area with a wooden reception desk, a digital screen, and seating arrangements.

8. Hit Hoteles Aeropuerto Puebla

Huejotzingo

Esmeralda

$69 nightly

$83 total

Nov 20 - Nov 21

Total with taxes and fees

A modern interior with a seating area, a white chair, and a wall with a geometric pattern and text.

A modern hotel lobby with a dining area, seating by the window, and a visible office space in the background.

A modern office space with a meeting room, desks, chairs, and computers.

A modern hotel room with a large bed, a television, and a view of the city through a window.

9. One Puebla Angelópolis Periférico

Tlaxcalancingo

Alejandro

$55 nightly

$65 total

Oct 25 - Oct 26

Total with taxes and fees

A modern interior with yellow chairs, a hanging chair, and large windows.

A modern restaurant interior with wooden paneling, colorful seating, and a large window with a view.

A hotel sign with the name 'tru by Hilton' and a colorful mural depicting a building with a cross on top.

A hotel room with a large window offering a view of a cityscape, including roads, buildings, and greenery.

10. Tru By Hilton Puebla Angelopolis

Angelópolis

Anouchka

$53 nightly

$63 total

Oct 28 - Oct 29

Total with taxes and fees

A rooftop pool with glass railings, a view of a cityscape, and a mountain in the background.

A modern lobby with a city view, featuring a yellow sofa, grey sofas, and green armchairs.

A modern dining area with tables and chairs, a buffet counter with food and drinks, and a city view through large windows.

A modern reception area with a wooden reception desk, a round table with a plant, and yellow chairs.

11. Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

Angelópolis

Martha

$61 nightly

$73 total

Oct 27 - Oct 28

Total with taxes and fees

A hotel with multiple balconies, a swimming pool, and outdoor seating areas.

A pool area with palm trees, a statue, and a modern building with multiple floors and balconies.

A spacious lobby with a modern design, featuring a seating area with sofas and tables, a staircase, and a reception desk.

A bar area with wooden tables and chairs, a wine rack, and a bar counter with bottles.

12. Camino Real Puebla Angelopolis

Angelópolis

HECTOR

$71 nightly

$85 total

Oct 25 - Oct 26

Total with taxes and fees

An indoor swimming pool with lounge chairs, large windows, and a view of the city at night.

A multi-story hotel with a prominent Fiesta Inn sign, a parking lot, and a view of the surrounding area.

A person sitting on a bed with a plate of food and a glass of orange juice.

A modern reception area with a white desk, multiple shelves with decorative items, and a patterned wall.

13. Fiesta Inn Express Puebla Explanada

Cholula

Ryan

$77 nightly

$93 total

Oct 26 - Oct 27

Total with taxes and fees

A lobby with a reception desk, a chandelier, a statue, and a sofa.

An elevator with a digital display, a statue, and a well-lit hallway with a tiled floor.

A restaurant with a bar area, multiple tables and chairs, and a large window offering a view.

A grand room with a piano, ornate chairs, and a chandelier.

14. Hotel Las Iglesias, Cholula

Cholula

Lesly

$55 nightly

$64 total

Oct 25 - Oct 26

Total with taxes and fees

A modern hotel lobby with a central spiral staircase, large windows, and a polished floor.

A modern building with a large illuminated sign reading "Hilton Garden Inn."

A modern lobby with a central seating area, large windows, and a television screen.

A modern interior with a curved staircase, glass railings, and two computer monitors on a wooden table.

15. Hilton Garden Inn Puebla Angelópolis, Mexico

Angelópolis

Pedro

$71 nightly

$85 total

Nov 8 - Nov 9

Total with taxes and fees

A modern lounge area with a city view, a bar with high stools, and plush seating.

A modern kitchen with marble countertops, wooden cabinets, and a central island.

A restaurant with a city view, modern decor, and a mix of seating arrangements.

A modern hotel room with a large bed, a desk, a TV, and a seating area.

16. Radisson Puebla Angelopolis

Angelópolis

Raúl Edmundo

$59 nightly

$70 total

Nov 2 - Nov 3

Total with taxes and fees

A modern hotel with a glass facade, multiple floors, and a prominent signage for 'Encore'.

A modern lobby with seating areas, a pool table, and a large screen.

A modern indoor pool with clear glass walls, a metal ladder, and a view of a cityscape at night.

A modern interior with a glass staircase, a reception desk, and a unique ceiling light fixture.

17. Ramada Encore by Wyndham Puebla

Coronango

Marisol

$66 nightly

$79 total

Nov 2 - Nov 3

Total with taxes and fees

A CityExpress Junior hotel with a modern design, featuring a large parking area and a well-lit entrance.

A hotel room with two beds, a TV, a window with a city view, and a green accent wall.

A reception desk with two computer monitors, a telephone, and a small printer. There are two white chairs and a red rug. The room has a tiled floor and pendant lights.

A modern conference room with a red carpet, white and gray sofas, a wooden coffee table, and potted plants.

18. City Express Junior by Marriott Puebla Angelopolis

Angelópolis

Oscar

$52 nightly

$62 total

Oct 23 - Oct 24

Total with taxes and fees

A spacious indoor area with multiple dining tables and chairs, a chandelier, and circular ceiling decorations with greenery.

A hotel room with two beds, a desk, and a computer.

A modern living room with a black sofa, patterned rug, and a large abstract painting on the wall.

A staircase with a black and gold railing, a chandelier, and a framed artwork on the wall.

19. Hotel Casa Real

Cholula

Chris

$37 nightly

$44 total

Oct 22 - Oct 23

Total with taxes and fees

A swimming pool with a covered area, lounge chairs, and a small table.

A long dining table set for a meal with chairs on both sides, a patterned runner down the center, and a decorative centerpiece.

A dining area with tables set for four, each with a vase of red flowers, silverware, and folded napkins. There are umbrellas and lounge chairs in the background, and a pool is visible.

A reception area with a wooden counter, framed certificates, and a clock.

20. Hotel Villas Arqueológicas Cholula

Cholula

Teresa

$64 nightly

$76 total

Oct 22 - Oct 23

Total with taxes and fees

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Top Santa Isabel Cholula Hotel Reviews

Quinta Real Puebla

10/10 Excellent

"This is an excellent property featuring impeccable rooms and amenities. Throughout our stay, the staff was remarkably helpful and welcoming. Additionally, the location is ideal, situated just a few blocks from the cathedral and the Zócalo."

Holiday Inn Puebla La Noria by IHG

8/10 Good

"Muy bueno el hotel, el staff muy amable. Lo único que la limpieza deja mucho que desear y faltan algunas amenidades como gorra de baño. Por lo demás muy bien."

NH Puebla Centro Histórico

10/10 Excellent

"Me gusta mucho"

voco Royalty Puebla Downtown by IHG

10/10 Excellent

"Very nice place and close to the plaza and enjoy the stay"

Hotel Boutique Casareyna

10/10 Excellent

"Excelente comida en el restaurante"

Four Points By Sheraton Puebla

8/10 Good

"Todo muy bien en general pero lo que más me gustó fue que tienen empatía con las mascotas tienen una perrita que adoptaron de la calle es muy linda y tranquila ella siempre está a la entrada del hotel tiene su camita la cuidan y le dan de comer le dicen guardiana muy bien por eso y cuando vuelva a Puebla de seguro llegaré a hospedarme de nuevo ahí por el buen servicio y por supuesto para saludar a Guyana. Muchas felicidades. Gracias"

Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

10/10 Excellent

"Clean rooms and the location was convenient"

Tru By Hilton Puebla Angelopolis

10/10 Excellent

"La ubicación, instalaciones, seguridad."

Hotel Escala Puebla Centro

8/10 Good

"Todo estubo bien"

More cheap stays in Santa Isabel Cholula

Hotel Teresita

Av 3 Pte 309 Puebla PUE

$21 nightly

$24 total

Nov 12 - Nov 13

Total with taxes and fees

8.6/10 Excellent! (424 reviews)

Posada Guadalupe

AVENIDA REFORMA NO. 301 COLONIA CENTRO Puebla PUE

$24 nightly

$28 total

Oct 21 - Oct 22

Total with taxes and fees

Hotel Aroma 406

2 NORTE 406 Puebla PUE

$30 nightly

$36 total

Nov 7 - Nov 8

Total with taxes and fees

8.4/10 Very Good! (231 reviews)

Hotel Sofia

3 Poniente no 319 Puebla PUE

$31 nightly

$37 total

Oct 28 - Oct 29

Total with taxes and fees

8.2/10 Very Good! (670 reviews)

Hotel Frida

Calle 2 Norte 206 Colonia Centro Puebla PUE

$39 nightly

$46 total

Nov 4 - Nov 5

Total with taxes and fees

8.2/10 Very Good! (349 reviews)

Kharma Suites

Av. del Castillo 5838 San Andrés Cholula PUE

$44 nightly

$53 total

Oct 21 - Oct 22

Total with taxes and fees

8.8/10 Excellent! (437 reviews)

Frequently asked questions

What's the best place to stay in Santa Isabel Cholula?

Holiday Inn Express Puebla by IHG, located 12.3 mi (19.8 km) from the heart of Santa Isabel Cholula, is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Camino Real Puebla Angelopolis and Four Points By Sheraton Puebla. See all available top hotels, or vacation rentals in Santa Isabel Cholula.

What are some of the best vacation home rentals that Santa Isabel Cholula has to offer?

Hotel de Guadalupe Puebla: Visitors like this Santa Isabel Cholula vacation home rental. It is in the city center and equipped with daily housekeeping and free WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Isabel Cholula.

If I need to cancel my hotel reservation in Santa Isabel Cholula, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel Cholula.

Where can I learn more about changing or cancelling my trip to Santa Isabel Cholula?

For additional details about changing or cancelling your trip to Santa Isabel Cholula, go to https://www.expedia.com/service/.

What is staying in Santa Isabel Cholula like?

Travelers to Santa Isabel Cholula will find plenty to explore and enjoy. In Santa Isabel Cholula, there are 2 hotels and other accommodations to choose from. Find out more about Santa Isabel Cholula.

What should I see while I'm in Santa Isabel Cholula?

Places to visit in the wider area include Atlixco Square, Explanada Shopping Center, and University Cultural Center of BUAP. You'll also find Metropolitan Auditorium and Palmas Plaza in the area. Check out what more to see and do in Expedia's Santa Isabel Cholula guide.

What's the weather like in Santa Isabel Cholula?

The hottest months are usually April and March with an average temp of 66°F, while the coldest months are January and December with an average of 61°F. The rainiest months in Santa Isabel Cholula are September, June, August, and July, with each month seeing an average of 13 inches of rainfall.

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Find hotels in Santa Isabel Cholula from $24

Go beyond your typical stay in Santa Isabel Cholula

Check prices for these dates

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Star rating

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Our top choices for Santa Isabel Cholula hotels

1. Hacienda Santo Cristo Hotel & Spa - Adults Only

2. BV Hotel Atlixco

3. Hotel Casa de la Audiencia

4. Soleil Inn Atlixco

5. Kharma Suites

6. Sonata Hotel

7. Hampton Inn & Suites by Hilton Puebla

8. Hit Hoteles Aeropuerto Puebla

9. One Puebla Angelópolis Periférico

10. Tru By Hilton Puebla Angelopolis

11. Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

12. Camino Real Puebla Angelopolis

13. Fiesta Inn Express Puebla Explanada

14. Hotel Las Iglesias, Cholula

15. Hilton Garden Inn Puebla Angelópolis, Mexico

16. Radisson Puebla Angelopolis

17. Ramada Encore by Wyndham Puebla

18. City Express Junior by Marriott Puebla Angelopolis

19. Hotel Casa Real

20. Hotel Villas Arqueológicas Cholula

Top Santa Isabel Cholula Hotel Reviews

Quinta Real Puebla

Holiday Inn Puebla La Noria by IHG

NH Puebla Centro Histórico

voco Royalty Puebla Downtown by IHG

Hotel Boutique Casareyna

Four Points By Sheraton Puebla

Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

Tru By Hilton Puebla Angelopolis

Hotel Escala Puebla Centro

More cheap stays in Santa Isabel Cholula

Hotel Teresita

Posada Guadalupe

Hotel Aroma 406

Hotel Sofia

Hotel Frida

Kharma Suites

Frequently asked questions

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