Santa Pera Vacation Rentals

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Our top choices for Santa Pera vacation rentals

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
$72 nightly
The price is $79
Jan 5 - Jan 6, 2026
Total with taxes and fees
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (222)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
$116 nightly
The price is $127
Jan 4 - Jan 5, 2026
Total with taxes and fees
Boutique Apartments Panama

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very Good, (50)
"The hotel as well as the room exceeded our expectations. I would recommend staying at the Yoo via expedia. Thanks again... Reggie"
United States
Reginald
$183 nightly
The price is $188
Dec 30 - Dec 31
Total with taxes and fees
Yoo Panamá by Boutique Apartments

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (175)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
$125 nightly
The price is $137
Jan 9 - Jan 10, 2026
Total with taxes and fees
Arcadia Condo Suites

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very Good, (28)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
$130 nightly
The price is $143
Jan 4 - Jan 5, 2026
Total with taxes and fees
Boutique Apartments Atlapa

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (171)
"The front desk receptionist was extremely helpful! The room was clean and comfortable! We would definitely stay again!"
United States
april
$152 nightly
The price is $168
Jan 7 - Jan 8, 2026
Total with taxes and fees
Las Clementinas

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista
9.6 out of 10, Exceptional, (56)
"Ron was amazing and so was the property!"
United States
John
$185 nightly
The price is $204
Jan 2 - Jan 3, 2026
Total with taxes and fees
Yoo Panama & Arts Tower

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
$153 nightly
The price is $171
Jan 11 - Jan 12, 2026
Total with taxes and fees
La Isabela Suites

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (485)
"Room was clean, neat great staff"
United States
Alfredo
$92 nightly
The price is $102
Jan 1 - Jan 2, 2026
Total with taxes and fees
Torres de Alba Hotel & Suites

Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
8.6 out of 10, Excellent, (20)
"It was absolutely wonderful. You just may need to bring your own soap for one of the bathrooms. Perhaps that was not typical though. I especially appreciated the cleanliness of the property, the view of the water, and the easy-to-use AC. "
United States
Tamu
$139 nightly
The price is $154
Jan 11 - Jan 12, 2026
Total with taxes and fees
Casa Love by Wynwood House

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
$149 nightly
The price is $162
Jan 18 - Jan 19, 2026
Total with taxes and fees
San Francisco by Wynwood House

YC 2301-C l Apartamento 2BR en av balboa

YC 2301-C l Apartamento 2BR en av balboa
2.0 star property
Bella Vista
9.6 out of 10, Exceptional, (4)
"Roberto the host was very accommodating with all our every need, from stowing our Luggage til room was ready to providing us Directions at all times during our stay. Gracias Roberto!!!"
United States
sonia
$150 nightly
The price is $165
Jan 4 - Jan 5, 2026
Total with taxes and fees
YC 2301-C l Apartamento 2BR en av balboa

Studio Apartment with Ocean View

Studio Apartment with Ocean View
3.0 star property
Calidonia
8.0 out of 10, Very Good, (2)
"It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps"
United States
Gwendolyn
$65 nightly
The price is $72
Jan 2 - Jan 3, 2026
Total with taxes and fees
Studio Apartment with Ocean View

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (57)
"We live this property and stay here whenever we are in town."
United States
chris
$83 nightly
The price is $91
Jan 4 - Jan 5, 2026
Total with taxes and fees
Casco View Apartments

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
$75 nightly
The price is $82
Dec 29 - Dec 30
Total with taxes and fees
La Palma Aparta Suite

Casa La Costa By Wynwood House

Casa La Costa By Wynwood House
3.5 star property
Casco Viejo
8.4 out of 10, Very Good, (20)
"Great location. At the border of renovated areas but an extremely go deal for this great property. "
United States
William
$144 nightly
The price is $160
Jan 4 - Jan 5, 2026
Total with taxes and fees
Casa La Costa By Wynwood House

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
$88 nightly
The price is $96
Jan 5 - Jan 6, 2026
Total with taxes and fees
Swette Love 10 Minutes From the Airport Tocumen

w Homely 2BR With Balcony in Panama

w Homely 2BR With Balcony in Panama
2.0 star property
Casco Viejo
$214 nightly
The price is $235
Jan 4 - Jan 5, 2026
Total with taxes and fees
w Homely 2BR With Balcony in Panama

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
$304 nightly
The price is $334
Jan 5 - Jan 6, 2026
Total with taxes and fees
Wanders Panama by Boutique Apartments

Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista
9.6 out of 10, Exceptional, (12)
"Great location"
United States
Jimmy Lee
$128 nightly
The price is $141
Jan 4 - Jan 5, 2026
Total with taxes and fees
Yoo Apartamento
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Pera Hotel Reviews

Find out more about Santa Pera

Everything you need to know about Santa Pera vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Pera vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Pera vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Pera vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Pera. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Pera in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $91 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Pera rentals

At Expedia, we put the best Santa Pera vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Pera rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Pera vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Pera. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Pera?

Yes, you can find vacation rentals near top attractions in Santa Pera, or you can go with a more secluded option if you want a relaxing place to stay.

What are some of the best vacation rentals that Santa Pera has to offer?

Oasis with pool near panama canal: This vacation home rental near Santa Pera offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

How many vacation rentals are there in Santa Pera?

Choose from 90 Expedia vacation rentals in Santa Pera for a memorable vacation.

What can I see and do in Santa Pera?

Explore the area and family-friendly sights such as Biomuseo, or get out into nature at a spot like Cinta Costera. In the larger area, you’ll find Albrook Shopping Mall and Metromall Panama.

What are vacation rentals like in Santa Pera?

Vacation rentals are private accommodations you can reserve for a few days or a quick weekend in Santa Pera. Vacation rentals feature extras like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you to travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for a small group gathering.