Title: Santa Pera Vacation Rentals from $88: Search Short-Term Rentals | Expedia.com [Hotels in Santa Pera](https://expedia.com/Santa-Pera-Hotels.d553248635975875222.Travel-Guide-Hotels)[Car Rentals in Santa Pera](https://expedia.com/Car-Rentals-In-Santa-Pera.d553248635975875222.Car-Rental-Guide)[Santa Pera Vacation Packages](https://expedia.com/Santa-Pera.d553248635975875222.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248635975875222&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=553248635975875222&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=553248635975875222&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=553248635975875222&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Pera vacation rentals ![Pool](https://images.trvl-media.com/lodging/120000000/119500000/119491100/119491061/ba91e704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119500000/119491100/119491061/307deaac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/120000000/119500000/119491100/119491061/w2048h1520x0y0-d8f377cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119500000/119491100/119491061/fb8cccf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3 Bedroom Apartment in San Miguelito, Panama City [](https://www.expedia.com/San-Miguelito-Hotels-Charming-3-Bedroom-Apartment-In-San-Miguelito.h119491061.Hotel-Information) José Domingo Espinar $156 nightly $156 total Apr 18 - Apr 19 Total with taxes and fees [](https://www.expedia.com/San-Miguelito-Hotels-Charming-3-Bedroom-Apartment-In-San-Miguelito.h119491061.Hotel-Information) ![Apartment, 3 Bedrooms, Accessible, Pool View | Pool | Outdoor pool](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/76eefaf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | Interior](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/5864a396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/3979bb6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | 3 bedrooms](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/094709c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3 Bedroom Apartment in San Miguelito, Panama City [](https://www.expedia.com/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information) José Domingo Espinar 2.0/10 (1 review) "La habitacion terrible, edificio sucio ubicacion pesima " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) caleb $99 nightly $107 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/2e90f0b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/71a0d50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/69e10c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/ec2b8abb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamento a 10 minutos del aeropuerto [](https://www.expedia.com/Panama-City-Hotels-Casa-De-Flores.h67311633.Hotel-Information) Panamá $76 nightly $82 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-De-Flores.h67311633.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/979e7b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/163d5c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/aef1fc6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/c727a57f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LILIA HOUSE 10 MINUTES AIRPORT [](https://www.expedia.com/Las-Mananitas-Hotels-LILIA-HOUSE-10-MINUTES-AIRPORT.h113731940.Hotel-Information) Panamá $73 nightly $79 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Las-Mananitas-Hotels-LILIA-HOUSE-10-MINUTES-AIRPORT.h113731940.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/34a0b683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/c45dedaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.6/10 Good (174 reviews) "The best place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio $178 nightly $195 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90100000/90090800/90090751/66eb3136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90100000/90090800/90090751/87eb95b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90100000/90090800/90090751/98339674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/91000000/90100000/90090800/90090751/849cdd33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamento a 10 minutos Aeropuerto Internacional de Tocumen #2 Panamá [](https://www.expedia.com/Panama-City-Hotels-Apartamento-A-10-Minutos-Aeropuerto-Internacional-De-Tocumen-2-Panama.h90090751.Hotel-Information) Don Bosco 8.0/10 Very Good (1 review) "Sweet little place with kind owners " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) roberta $82 nightly $88 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Apartamento-A-10-Minutos-Aeropuerto-Internacional-De-Tocumen-2-Panama.h90090751.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.6/10 Good (34 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/121000000/120390000/120383000/120382972/dfe9a196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120390000/120383000/120382972/996af3aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120390000/120383000/120382972/448661bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/121000000/120390000/120383000/120382972/c11936b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Apt+WiFi+Kitchen+AC+Laundry+TV+Parking@Panamá [](https://www.expedia.com/Panama-City-Hotels-Vrbo-Property.h120382972.Hotel-Information) Parque Lefevre $65 nightly $68 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Vrbo-Property.h120382972.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/7cba0a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/737ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (263 reviews) "Great central location! Great price. Clean. Nice pool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Armin $133 nightly $146 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/db0d74a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/4ff14cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/961aa914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/240bd855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama View House – A Hilltop Retreat with Stunning Canal Views [](https://www.expedia.com/Panama-City-Hotels-Panama-View-House-A-Hilltop-Retreat-With-Stunning-Canal-Views.h112897674.Hotel-Information) Panama City $96 nightly $96 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Panama-View-House-A-Hilltop-Retreat-With-Stunning-Canal-Views.h112897674.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/87d5a99d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/c9888658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/1cbda3e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/be270857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Living 73 Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Living-73.h122657050.Hotel-Information) San Francisco $173 nightly $208 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Living-73.h122657050.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/278cb749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/e4d966c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/71ba504e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/1dd9ed4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury 1 bedroom apt free parking and Pool [](https://www.expedia.com/Panama-City-Hotels-Luxury-1-Bedroom-Apt-Free-Parking-And-Pool.h106265914.Hotel-Information) San Francisco 10/10 Exceptional (1 review) "El apto está muy bueno con vistas espectaculares. La limpieza impecable y la atención muy buena. El sitio dónde está ubicado es de los mejores de la ciudad." ![Spain](https://a.travel-assets.com/egds/marks/flags/es.svg) Ricardo Alejandro $156 nightly $156 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Luxury-1-Bedroom-Apt-Free-Parking-And-Pool.h106265914.Hotel-Information) ![Apartment, 1 Bedroom, Balcony | Property grounds](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/60c2353e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Interior](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/c6afccbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Interior](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/a60e8488.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Dining](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/65d48e93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swette Love 10 Minutes From the Airport Tocumen [](https://www.expedia.com/Las-Mananitas-Hotels-Swette-Love-10-Minutes-From-The-Airport-Tocumen.h120194409.Hotel-Information) Las Mañanitas $69 nightly $75 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Mananitas-Hotels-Swette-Love-10-Minutes-From-The-Airport-Tocumen.h120194409.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/c0384242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Double Beds | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.com/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) Bella Vista 8.8/10 Excellent (522 reviews) "Very clean and amazing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo $92 nightly $101 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (239 reviews) "The stay was wonderful and seamless they are very friendly and efficient as always" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford $162 nightly $178 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![TV, offices](https://images.trvl-media.com/lodging/97000000/96680000/96673200/96673111/a2a9c827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/97000000/96680000/96673200/96673111/dd0ab8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/97000000/96680000/96673200/96673111/6adefdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96680000/96673200/96673111/e06fd5cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### w\* | Engaging 1BR w/ Balcony in Casco Viejo [](https://www.expedia.com/Panama-City-Hotels-W-Chic-1BR-W-Balcony-In-Casco-Viejo.h96673111.Hotel-Information) Casco Viejo 8.8/10 Excellent (3 reviews) "Need to post more specific photos of the area surrounding the hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jimmy Lee $107 nightly $107 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-W-Chic-1BR-W-Balcony-In-Casco-Viejo.h96673111.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/108000000/107360000/107357500/107357433/1fba0599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107360000/107357500/107357433/c87d0437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107360000/107357500/107357433/7b198ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/108000000/107360000/107357500/107357433/e404f9e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury 2 bedroom apt free parking and Pool [](https://www.expedia.com/Panama-City-Hotels-Luxury-2-Bedroom-Apt-Free-Parking-And-Pool.h107357433.Hotel-Information) San Francisco 10/10 Exceptional (2 reviews) "Lorenzo, the host was very responsive to my emails, and communication about the unit was very clear. The apartment was clean and spacious. The air conditioners worked perfectly. The condo is in a good location, a few blocks from a couple of supermarkets. Having a washer & dryer was a plus. If you're facing the building from the street, the concierge/office is in the front on the bottom floor. I had difficulty recognizing the concierge office at night at time of checkin. If you're facing the... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernie P. $173 nightly $173 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Luxury-2-Bedroom-Apt-Free-Parking-And-Pool.h107357433.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.0/10 Very Good (72 reviews) "Great Apartment clean, excellent ocean view. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $214 nightly $221 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052663/e073b1c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052663/c788c2f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052663/0ac88eee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052663/772474da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful apartment for 2 in the Old Town | M2 [](https://www.expedia.com/Panama-City-Hotels-Nice-Apartment-With-Jacuzzi-And-Rooftop-P2.h89052663.Hotel-Information) Casco Viejo 10/10 Exceptional (2 reviews) "This location in Casco puts you in the best position to enjoy all the historical and modern attractions afforded to this beautiful Panama neighborhood. You will feel like a local and be treated like a dignitary." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike M. $109 nightly $115 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Nice-Apartment-With-Jacuzzi-And-Rooftop-P2.h89052663.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052644/d9a702ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052644/fdca1100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, Netflix, streaming services](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052644/d485e939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/90000000/89060000/89052700/89052644/a27d3b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Apartment with Balcony | Casco Viejo | M1 [](https://www.expedia.com/Panama-City-Hotels-Gorgeous-Apartment.h89052644.Hotel-Information) Casco Viejo 9.2/10 Wonderful (5 reviews) "The room was absolutely clean and wonderful, but the spa was under construction until the last day" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremiah T. $126 nightly $133 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Gorgeous-Apartment.h89052644.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-01&endDate=2026-04-02®ionId=553248635975875222&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=APARTMENT) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=APART_HOTEL) Villas [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=VILLA) Condos [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CONDO) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=VACATION_HOME) Cabins [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CABIN) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=HOUSE_BOAT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=COTTAGE) Chalets [](https://www.expedia.com/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Pera-Vacation-Rentals.d553248635975875222.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Pera-Vacation-Rentals.d553248635975875222.Travel-Guide-VacationRentals) ## Top Santa Pera Hotel Reviews ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Truly enjoyed our stay" [](https://expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 6/10 Okay "Staff was great but the hotel needs an upgrade. " [](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Hotel in a very convenient location. On this occasion as the Queen rooms were not available we booked a junior suite which we thought would be one of the rooms with a kitchenette area however it was a rather strange room with a lounge area and a bath in the bathroom. There was supposed to be a coffee machine according to the booking but there wasn’t one - they provided one. Unfortunately the room was on the seventh floor and the WiFi does not work well on the area of that floor. In general the room and hotel were fine. AC TV etc worked well." [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 10/10 Excellent "J’ai bien aimé cette hôtel bon rapport qualité prix! Le personnel était vraiment sympathique. " [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e50f6f0f_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "All was amazing " [](https://expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 6/10 Okay "Room was OK. Close to airport which is convenient for a quick stay. TV was old and screen barely worked. Bartender tried to charge us almost $100 USD for 2 drinks. After I questioned they changed it to $20 so be sure to check your bill!" [](https://expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Hotel is perfectly situated in the middle of the city, the hotel dos need some improvement as does look tired. Staff is amazing and the amenities are great. Breakfast is fantastic and service by the pool is also great. " [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0_y.jpg) ### Hyatt Regency Panama City 10/10 Excellent "Great place in Financial District. The hotel had constant conferences so a little crowded. " [](https://expedia.com/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "The spa was amazing, I never went to a spa that washes your feet before a massage. What an amazing experience. Job well done. The hotel was so nice and our room omg just beautiful, we stayed in the supreme corner room and enjoyed every moment. Next time we have to stay a longer time because our 5 days and 4 nights went by so quickly. Keep up the good work to all the staff, front desk staff, room service staff and house keeping were all amazing. Thank you all. " [](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ## Find out more about Santa Pera **Everything you need to know about Santa Pera vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Pera vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Pera vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Santa Pera vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Pera. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Pera in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $88 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Santa Pera rentals** At Expedia, we put the best Santa Pera vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Santa Pera rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Pera vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Pera. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) ## Frequently asked questions ### Are there vacation rentals in Santa Pera? ### What are some of the best vacation rentals that Santa Pera has to offer? ### How many vacation rentals are there in Santa Pera? ### What can I see and do in Santa Pera? ### What are vacation rentals like in Santa Pera? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app