Find hotels in Santa Rosa from $35

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Rosa hotels

ONDA Boquete

ONDA Boquete
3.0 star property
Boquete
8.8 out of 10, Excellent, (35)
"The staff was very friendly and helpful! Would stay again, no question!"
United States
Mark
$41 nightly
The price is $45
Jan 23 - Jan 24, 2026
Total with taxes and fees
ONDA Boquete

Aranjuez Hotel & Suites

Aranjuez Hotel & Suites
3.5 star property
David Sur
9.2 out of 10, Wonderful, (771)
"Wonderful staff & great restaurant"
United States
KAREN
$68 nightly
The price is $76
Jan 4 - Jan 5, 2026
Total with taxes and fees
Aranjuez Hotel & Suites

Cabanas Rio Encantado

Cabanas Rio Encantado
3.0 star property
Caldera
9.4 out of 10, Exceptional, (40)
"This was our favorite place. Clean, gorgeous grounds, comfortable rooms, killer pool, riverside, very accommodating host. Love, love, love."
United States
Kristin
$102 nightly
The price is $113
Jan 13 - Jan 14, 2026
Total with taxes and fees
Cabanas Rio Encantado

Hotel Ciudad De David

Hotel Ciudad De David
3.5 star property
David
9.4 out of 10, Exceptional, (1000)
"Very clean and comfortable hotel, great location! Restaurant with good food and large menu. Staff was amazing and very friendly!"
United States
David
$74 nightly
The price is $81
Jan 11 - Jan 12, 2026
Total with taxes and fees
Hotel Ciudad De David

Aires frescos de Boquete

Aires frescos de Boquete
2.0 star property
Alto Boquete
9.0 out of 10, Wonderful, (4)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
$52 nightly
The price is $57
Dec 28 - Dec 29
Total with taxes and fees
Aires frescos de Boquete

Hotel City Plaza & Suites

Hotel City Plaza & Suites
3.5 star property
David Sur
9.2 out of 10, Wonderful, (176)
"Nice room and bathroom. The AC is rather loud and the location of the hotel not very nice. "
Germany
Nadine
$63 nightly
The price is $71
Dec 26 - Dec 27
Total with taxes and fees
Hotel City Plaza & Suites

Hotel Castilla

Hotel Castilla
3.0 star property
David
8.4 out of 10, Very Good, (184)
"The entire hotel was impeccably clean. The staff was kind and helpful. If you travel frequently, you may be surprised by the lack of amenities. No mini fridge, microwave, hair dryer, safe or iron. No free breakfast in the on site restaurant. We were hap Please note that speaking Spanish will be to your advantage in the hotel. This place is in the heart of local David culture near Plaza Cervantes. We stayed there for 3 days at the end of the rainy season on Mother's Day weekend. We had an...
United States
Mona
$50 nightly
The price is $55
Dec 26 - Dec 27
Total with taxes and fees
Hotel Castilla

Hampton by Hilton David

Hampton by Hilton David
3.0 star property
David Sur
9.2 out of 10, Wonderful, (494)
"entire stay was superb. Location, quality of staff, decor, entertainment, great beds."
United States
Richard
$86 nightly
The price is $95
Dec 28 - Dec 29
Total with taxes and fees
Hampton by Hilton David

Lucero - Luxury Treehouses

Lucero - Luxury Treehouses
3.5 star property
Jaramillo
8.6 out of 10, Excellent, (4)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
$227 nightly
The price is $249
Dec 29 - Dec 30
Total with taxes and fees
Lucero - Luxury Treehouses

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
$50 nightly
The price is $55
Jan 3 - Jan 4, 2026
Total with taxes and fees
Linda Vista Cabins

Boquete Guest House Alto Boquete

Boquete Guest House Alto Boquete
3.0 star property
Alto Boquete
$70 nightly
The price is $77
Dec 26 - Dec 27
Total with taxes and fees
Boquete Guest House Alto Boquete

Hotel Crown Mirage

Hotel Crown Mirage
2.0 star property
David Sur
8.4 out of 10, Very Good, (5)
$35 nightly
The price is $38
Dec 26 - Dec 27
Total with taxes and fees
Hotel Crown Mirage

Hacienda Los Molinos Boutique Hotel

Hacienda Los Molinos Boutique Hotel
3.5 star property
Alto Boquete
9.2 out of 10, Wonderful, (93)
"Beautiful, clean, amazing staff, and excellent food! "
United States
Wanda
$159 nightly
The price is $176
Jan 8 - Jan 9, 2026
Total with taxes and fees
Hacienda Los Molinos Boutique Hotel

Los Establos Boutique Resort- All Inclusive

Los Establos Boutique Resort- All Inclusive
4.5 star property
Jaramillo
9.6 out of 10, Exceptional, (21)
"Very beautiful and special place."
United States
SVETLANA
$454 nightly
The price is $506
Jan 10 - Jan 11, 2026
Total with taxes and fees
Los Establos Boutique Resort- All Inclusive

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.8 out of 10, Excellent, (130)
"Priced right, easy walk to town, safe, quiet & overall great stay! "
United States
John
$74 nightly
The price is $83
Dec 26 - Dec 27
Total with taxes and fees
Villa Alejandro

Tree Trek Boquete Adventure Park

Tree Trek Boquete Adventure Park
3.0 star property
Los Naranjos
9.0 out of 10, Wonderful, (191)
"My husband and I had a great 3-night stay at Tree Trek, our first trip to the Boquete region and couldn’t have been happier with our stay. A special place that we enjoyed and would return. The Superman zipline, honey and rum tasting as well as the dining were all excellent. "
United States
Moki
$119 nightly
The price is $132
Jan 20 - Jan 21, 2026
Total with taxes and fees
Tree Trek Boquete Adventure Park

MOMA Guest House

MOMA Guest House
2.0 star property
Brisas de Alto Boquete
10.0 out of 10, Exceptional, (2)
"Me encantó. Repetiría la experiencia 💓"
Mexico
astrid
$41 nightly
The price is $46
Jan 4 - Jan 5, 2026
Total with taxes and fees
MOMA Guest House

Gran Hotel Nacional

Gran Hotel Nacional
3.0 star property
Barrio El Carmen
8.4 out of 10, Very Good, (512)
"Great place , to stay in David "
United States
Helge
$86 nightly
The price is $94
Dec 26 - Dec 27
Total with taxes and fees
Gran Hotel Nacional

Rio Verde by Villa Alejandro

Rio Verde by Villa Alejandro
2.5 star property
Los Naranjos
9.4 out of 10, Exceptional, (86)
"All was great here, especially the dound of the river at night.Staff was very helpful and out Virtual checkin and out was a breeze"
United States
Paul
Rio Verde by Villa Alejandro

Hotel Madrid Chiriqui

Hotel Madrid Chiriqui
2.5 star property
David
7.8 out of 10, Good, (16)
"The staff was friendly and nice. The hotel has a restaurant on site which is a plus. I came in from Bocas del Toro and had to catch a flight next morning. It was perfect for the overnight stay I needed. "
United States
Jadid
Hotel Madrid Chiriqui
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Rosa Hotel Reviews

More cheap stays in Santa Rosa

Hotels in Santa Rosa with star-rating

Frequently asked questions

What's the best place for a stay in Santa Rosa?
Located 21.4 mi (34.5 km) from the heart of Santa Rosa, Hotel Ciudad De David is a top choice for your stay based on our traveler data. Two other options for your stay in the area are Aranjuez Hotel & Suites and Hampton by Hilton David. See all available top hotels, or vacation rentals in Santa Rosa.
What's the top vacation rental that Santa Rosa has to offer?
House in Boquete with king beds and hot tub: This vacation home rental outside of Santa Rosa is located in the mountains and has a balcony, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the hot tub in this rental home to help you unwind. See all vacation rentals in Santa Rosa.
If I need to cancel my hotel reservation in Santa Rosa, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Rosa.
Where can I learn more about changing or cancelling my trip to Santa Rosa?
For additional details about picking new dates or cancelling your trip to Santa Rosa, head over to our customer service page.
What is staying in Santa Rosa like?
Visitors are sure to enjoy all that Santa Rosa has to offer. There are 245 hotels and other accommodations in the surrounding area. Find out more about Santa Rosa.
What should I do while I'm visiting Santa Rosa?
Places to visit in the wider area include Las Cavernas de Corredores, Finca Lérida Coffee Estate, and Finca Dracula Orchid Sanctuary. You'll also find Arte Cruz Volcán and Barriles in the area. Check out what more to see and do in Expedia's Santa Rosa guide.
What's the weather like in Santa Rosa?
The hottest months are usually March and February with an average temp of 78°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa Rosa are October, November, August, and July, with each month seeing an average of 30 inches of rainfall.