Find hotels in Santa Rosa from $32

Go beyond your typical stay in Santa Rosa

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Nov 11 - Nov 12
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Nov 12 - Nov 13
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

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Our top choices for Santa Rosa hotels

A hotel with a swimming pool, a covered area, and a multi-story building with balconies.

1. Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
Colon
8.0 out of 10, Very good, (825 reviews)
"Excellent stay"
United States
David
$135 nightly
The price is $149
Nov 15 - Nov 16
Total with taxes and fees
Gamboa Rainforest Reserve
A swimming pool with a water feature, surrounded by plants and seating areas.

2. Holiday Inn Panama Canal by IHG

Holiday Inn Panama Canal by IHG
3.5 star property
Panama City
8.6 out of 10, Excellent, (511 reviews)
"the view of ships passing thru the Panama Canal was very nice! very comfortable stay, will definitely stay at IHG properties again"
United States
ronald
$108 nightly
The price is $119
Nov 29 - Nov 30
Total with taxes and fees
Holiday Inn Panama Canal by IHG
A poolside area with lounge chairs and a covered seating area, reflecting the pool and surrounding structures.

3. Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive
4.0 star property
Panama City
8.4 out of 10, Very good, (1,001 reviews)
"Had a great stay. Loved the rainforest vibes"
United States
Joanna
$220 nightly
The price is $242
Nov 12 - Nov 13
Total with taxes and fees
Summit Rainforest Golf Resort & All Inclusive
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

4. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.2 out of 10, Wonderful, (1,008 reviews)
"Very nice, easy access to airport"
United States
Hector
$101 nightly
The price is $111
Nov 27 - Nov 28
Total with taxes and fees
Courtyard by Marriott Panama Metromall
A modern living room with a sofa, coffee table, and chairs. There is a dining area in the background with tables and chairs.

5. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania
9.0 out of 10, Wonderful, (817 reviews)
"Everything is very clean and the staff super helpfull!"
United States
Kira
$100 nightly
The price is $110
Nov 21 - Nov 22
Total with taxes and fees
Best Western El Dorado Panama Hotel
A pool area with a covered patio, outdoor seating, and a bar area.

6. Albrook Inn

Albrook Inn
3.0 star property
Panama City
8.0 out of 10, Very good, (658 reviews)
"It was good for the price, very close to the Albrook airport and a short drive to the mall. Fun walking trail, good restaurant, and the the breakfast was included"
United States
Mario
$58 nightly
The price is $64
Nov 20 - Nov 21
Total with taxes and fees
Albrook Inn
A modern lobby with a curved ceiling, seating area with chairs and a sofa, and artwork on the walls.

7. Hotel y Casino Central Park Panama

Hotel y Casino Central Park Panama
3.0 star property
Bethania
7.6 out of 10, Good, (505 reviews)
"The rooms were clean, spacious, the staff was very helpful, breakfast options limited but was good"
United States
Shadé
$61 nightly
The price is $67
Dec 12 - Dec 13
Total with taxes and fees
Hotel y Casino Central Park Panama
A resort with a pool area, lounge chairs, and a view of a bridge at night.

8. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,014 reviews)
"I love the location. Very friendly staff"
United States
Kevin
$78 nightly
The price is $85
Nov 12 - Nov 13
Total with taxes and fees
Radisson Hotel Panama Canal
A spacious lobby with a reception desk, seating area, and a second-floor balcony.

9. SAND DIAMOND HOTEL

SAND DIAMOND HOTEL
3.0 star property
Colon
8.6 out of 10, Excellent, (336 reviews)
"Beautiful hotel, close to everything in Colon. The breakfast was delicious and fresh. Would stay again in the future."
United States
Monica
$100 nightly
The price is $110
Dec 11 - Dec 12
Total with taxes and fees
SAND DIAMOND HOTEL
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

10. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.2 out of 10, Wonderful, (1,004 reviews)
"Excellent location"
United States
Guadalupe
$178 nightly
The price is $196
Dec 4 - Dec 5
Total with taxes and fees
Marriott Panama Hotel
A hotel entrance with a central water feature, seating areas, and potted plants.

11. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (772 reviews)
"Everything was top notch"
United States
Denis
$314 nightly
The price is $346
Nov 27 - Nov 28
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A rooftop pool with a city view, lounge chairs, and a clear sky.

12. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (423 reviews)
"Great place to stay"
United States
Elijah
$127 nightly
The price is $140
Nov 22 - Nov 23
Total with taxes and fees
Corporate Stays Arcadia | Executive Furnished Apartments
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

13. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,014 reviews)
"It was a great stay! I would stay here again!"
United States
Brittney
$131 nightly
The price is $144
Nov 21 - Nov 22
Total with taxes and fees
Aloft by Marriott Panama
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.

14. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (2,141 reviews)
"Very economically priced for a short comfortable stay whilst on holiday or business"
United States
Lisa
$59 nightly
The price is $65
Nov 12 - Nov 13
Total with taxes and fees
Principe Hotel and Suites
A balcony with wicker chairs and a view of the cityscape.

15. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,428 reviews)
"Great location and breakfast buffet was great"
United States
Luis
$119 nightly
The price is $131
Nov 16 - Nov 17
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica
A rooftop pool with a city view, modern architecture, and outdoor seating.

16. The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (356 reviews)
"Hotel was ok"
United Kingdom
Luke
$283 nightly
The price is $311
Dec 5 - Dec 6
Total with taxes and fees
The Westin Panama
A swimming pool with lounge chairs and palm trees, surrounded by modern buildings.

17. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
"Room was clean and staff was helpful"
United States
Jheanell
$194 nightly
The price is $213
Nov 20 - Nov 21
Total with taxes and fees
Sheraton Grand Panama
A rooftop pool area with lounge chairs and a view of a port with cranes.

18. Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
4.0 star property
Barrio Sur
8.2 out of 10, Very good, (995 reviews)
"had a great time there. Javier the receptionist Was a great help to us"
United Kingdom
Fanella
$116 nightly
The price is $128
Nov 24 - Nov 25
Total with taxes and fees
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
A view from a balcony with a cityscape in the background, featuring tall buildings and a body of water.

19. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,250 reviews)
"We loved our stay, staff was very helpful, the hotel is very well located, and the breakfast is to die for!"
United States
CLAUDIA
$92 nightly
The price is $101
Nov 14 - Nov 15
Total with taxes and fees
Plaza Paitilla Inn Hotel
A hotel entrance with a glass door, a chandelier, and a wall of greenery.

20. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,044 reviews)
"Great Staff, very helpful, great breakfast."
United States
Ruben
$83 nightly
The price is $91
Nov 13 - Nov 14
Total with taxes and fees
Riande Urban Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in Santa Rosa

A hotel with a swimming pool, a covered area, and a multi-story building with balconies.

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
Colon
8.0 out of 10, Very good, (825)
$135 nightly
The price is $149
Nov 15 - Nov 16
Total with taxes and fees
Gamboa Rainforest Reserve

Top Santa Rosa Hotel Reviews

Front of property
Gatun Lake Lodge Hotel

Gatun Lake Lodge Hotel

Gatun Lake Lodge Hotel
Pueblo Nuevo

10/10 Excellent

Excellent
United States
Nestor
Reviewed September 30, 2026
Gatun Lake Lodge Hotel

Frequently Asked Questions

What is the best area to stay in Santa Rosa?

The best area to stay in Santa Rosa for most travelers is the city center, particularly around Avenida Central and the Parque Central.

This area is the heart of Santa Rosa, offering a convenient base for exploring the city. You'll find a concentration of local businesses, dining options, and access to public transportation. The Parque Central is a key landmark, providing a central gathering spot.

For travelers who appreciate convenience and easy access to local amenities, staying in the city center is ideal.

When is the best time to go to Santa Rosa?

The best time to visit Santa Rosa, Colón, Panama, is during the dry season, which runs from mid-December to mid-April. This period offers the most comfortable weather for exploring.

During these months, you'll experience sunny days with lower humidity and minimal rainfall, making it ideal for outdoor activities like hiking, wildlife viewing, and enjoying the beaches. The clearer skies also provide better conditions for photography and sightseeing.

Travelers looking for a relaxed and pleasant experience will find this time particularly suitable.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Rosa.

How much is the nightly rate at a Santa Rosa hotel?

Prices for hotels in Santa Rosa often vary, but you can find a great deal from $32 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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