Santiago Matatlán Vacations from $490

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Your Santiago Matatlán Vacation

Our Santiago Matatlán vacation packages give you the power to customize your own adventure. Tailor your journey to your needs and interests and make every moment count in this fabulous city. Fill your trip to Santiago Matatlán with visits to its top attractions. Where to first? You won't want to miss Mitla. No matter your travel plans or the size of your budget, putting together a tailored Santiago Matatlán vacation is simple with Expedia.

The Latest Santiago Matatlán vacation packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Emperador, Oaxaca

OYO Hotel Emperador, Oaxaca

Oaxaca Centro
$490
per person
Nov 2 - Nov 5
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Oaxaca Intl. (OAX)
5.8/10 (266 reviews)
Casa 1800 Oaxaca Boutique Hotel

Casa 1800 Oaxaca Boutique Hotel

Oaxaca Centro
Save 100% on your flight
$827
per person
Nov 2 - Nov 5
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (82 reviews)
Staff very friendly and very close to walking around

Reviewed on Aug 4, 2026

Casa Quiote Hotel Boutique City Center based - Adults Only

Casa Quiote Hotel Boutique City Center based - Adults Only

Oaxaca Centro
$986
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Oaxaca Intl. (OAX)
9/10 Wonderful! (73 reviews)
Buena atención la habitación muy limpia, lugar cerca de todo 10 de 10 muy recomendable

Reviewed on Jul 30, 2026

Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique

San Felipe del Agua
Save 100% on your flight
$862
per person
Nov 2 - Nov 5
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Oaxaca Intl. (OAX)
9/10 Wonderful! (213 reviews)
Holiday Inn Express Oaxaca-Centro Historico by IHG

Holiday Inn Express Oaxaca-Centro Historico by IHG

Ruta Independencia
Save 100% on your flight
$621
per person
Oct 8 - Oct 15
found 1 day ago
Roundtrip flight included
Tijuana (TIJ) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (1,005 reviews)
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What to do in Santiago Matatlán

Mobile barrel

Oaxaca Mezcal & Pulque Tour by Barrel Bus

$79
per adult
Oaxaca Mezcal & Pulque Tour by Barrel Bus
Hierve el Agua Early Tour with Pickup + smoke-kitchen

Hierve el Agua Early Tour with Pickup + smoke-kitchen

$50
per adult
100% of travellers recommend
Hierve el Agua Early Tour with Pickup + smoke-kitchen
Start of mezcal production process

Distillery Tour and Agave Fields by Mal de Amor Mezcal

$69
per adult
Distillery Tour and Agave Fields by Mal de Amor Mezcal
See all activities in Santiago Matatlán

Santiago Matatlán Hotel Deals

Hotel Hacienda

Hotel Hacienda

Av Eduardo Mata 1918 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$63 nightly
$75 total
Aug 9 - Aug 10
Total with taxes and fees
9/10 Wonderful! (1,006 reviews)
"It was ok ,,wifi didn't work so kids were bummed ,other than that not bad"

Reviewed on Aug 7, 2026

Hotel Hacienda
Fiesta Inn Oaxaca

Fiesta Inn Oaxaca

Av. Universidad 140 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$96 nightly
$114 total
Sep 4 - Sep 5
Total with taxes and fees
8.8/10 Excellent! (1,005 reviews)
"Good place"

Reviewed on Aug 6, 2026

Fiesta Inn Oaxaca
OYO Hotel Rey David, Oaxaca

OYO Hotel Rey David, Oaxaca

16 de Septiembre 248 Ocotlán de Morelos OAX
Fully refundableReserve now, pay when you stay
$22 nightly
$26 total
Aug 8 - Aug 9
Total with taxes and fees
4/10 (42 reviews)
"Hoyo deberia revisar bien las condiciones acordadas"

Reviewed on Apr 6, 2026

OYO Hotel Rey David, Oaxaca
See all 157 properties in Santiago Matatlán
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santiago Matatlán Vacation Packages

Santiago Matatlán Essential Information

Language
Spanish
Currency
Mexican pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Xoxocotlan Intl. Airport (OAX)
Population
3,400
Top Sights
Tlacolula Market, Mitla Archaeological Site and Ancient Mitla

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Frequently asked questions

How much does a Santiago Matatlán vacation package cost?
Offering excellent value package deals from $490 on Expedia, you'll be pleasantly surprised at how much a vacation to Santiago Matatlán costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Santiago Matatlán?
If you're looking to book a cheap Santiago Matatlán vacation package, consider planning a trip in January, June and December. You'll generally find better prices on flights and accommodations during these months — ideal for a budget-friendly break.
How many days is enough for Santiago Matatlán?
Usually, a handful of days is enough to see the major attractions during your Santiago Matatlán vacation. However, if you want to have more time to unwind or go on day trips, think about extending your trip.
How to find the best Santiago Matatlán package deals?
Start your search for a Santiago Matatlán package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add some filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect Santiago Matatlán package deal straight away, simply tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santiago Matatlán escape off to a flying start.
Is it cheaper to book a Santiago Matatlán vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking hotels and flights separately. Better still, you can personalize your Santiago Matatlán trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santiago Matatlán?
If you have your Santiago Matatlán travel dates finalized, book as early as you can to grab some unbeatable deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous trips? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Santiago Matatlán?
  1. Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to visit Santiago Matatlán.
  2. Set a budget: Consider costs such as food, flights and transportation when working out how much to put aside for your trip to Santiago Matatlán. Then, choose a hotel that matches your budget, whether that's a wallet-friendly option or a swankier retreat.
  3. Explore Santiago Matatlán using our trip planning tool: Gain insights into the top attractions and best stays for your trip to Santiago Matatlán. You can also save your favorite locations, collaborate with your group and organize your plans in one place.
  4. Set the duration of your trip: Start by making a list of all the attractions you want to experience in Santiago Matatlán. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left now is to find a Santiago Matatlán vacation package that brings all your bookings together.
  6. Book experiences or activities in advance: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on Santiago Matatlán's highlights. Find all the incredible things to do in Santiago Matatlán with our dedicated travel guide.
Does Expedia offer Book Now, Pay Later Santiago Matatlán vacation packages?
If you're like us, you love jet-setting around the world but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the cost of your Santiago Matatlán vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.