Santo Antonio Vacations from $848
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Your Santo Antonio Vacation
From its shopping to its cafes and culture, there are tons of good reasons to book a vacation package to Santo Antonio. When you need to get away from it all, this commercial neighborhood has a spot just for you. When it's time to sightsee, you'll find plenty of big-name attractions nearby including Castle of São Jorge, Rossio Square and Lisbon Cathedral. Tick off one or all during your trip to Santo Antonio. Expedia is here to put your travel plans into action. Book your ultimate Santo Antonio vacation today.
The Latest Santo Antonio vacation packages
Price found within the past 48 hours. Click for updated prices.
Casa dell'Arte Club House
Lisbon Old Town
Price was $1,594, price is now $1,175 per person
$1,175
per person
Jan 13 - Jan 18
found 15 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Lisbon (LIS)
9.6/10 Exceptional! (82 reviews)
It’s an amazingly beautiful place! The staff was very kind, sweet and helpful!
We would definitely stay here again
Reviewed on Nov 1, 2026
The Homeboat Company Parque das Nações
Price was $4,328, price is now $2,811 per person
$2,811
per person
Dec 30 - Jan 4
found 1 day ago
Roundtrip flight included
Boston (BOS) to Lisbon (LIS)
10/10 Exceptional! (28 reviews)
We absolutely loved our stay! Everything was amazing, the staff was so welcoming and attentive, and the breakfasts were delicious. We had such a wonderful experience and would happily stay here again. Highly recommend!
Reviewed on Nov 8, 2026
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What to do in Santo Antonio
Lisbon: Sintra, Pena, Regaleira & Cabo Roca & Cascais Coast
$40
per adult
92% of travellers recommend
Lisbon: Sintra, Pena, Regaleira, Cabo da Roca, and Cascais
$32
per adult
92% of travellers recommend
From Lisbon: Sintra, Pena Palace and Quinta da Regaleira
$29
per adult
94% of travellers recommend
Santo Antonio Hotel Deals
Locke de Santa Joana
18 Rua Camilo Castelo Branco Lisbon
$90 nightly
The price is $104 total per night from Dec 7 to Dec 8
$104 total
Dec 7 - Dec 8
Total with taxes and fees
easyHotel Lisbon
R. de Santa Marta 60 Lisbon
$52 nightly
The price is $64 total per night from Nov 22 to Nov 23
$64 total
Nov 22 - Nov 23
Total with taxes and fees
8.8/10 Excellent! (1,784 reviews)
"Le personnel était très gentil et serviable. Nous ont prêté des parapluies. Nous ont aidé à contacter notre compagnie aérienne en raison des bouleversements causés par Charles. Les chambres sont extrêmement petites. Salles de bain neuves et propres. Resto dejeuner dans lhotel. Bien situé près du ..."
Reviewed on Nov 11, 2026
EPIC SANA Marques Hotel
Avenida Fontes de Pereira de Melo, 8 Lisbon
$223 nightly
The price is $246 total per night from Dec 4 to Dec 5
$246 total
Dec 4 - Dec 5
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santo Antonio Vacation Packages
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Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
