Santo Tomé

Travel Guide

A person holding a yerba mate cup with a snowy mountain range and a lake in the background.
A hand holding a yerba mate cup with a metal straw, set against a backdrop of a lake and snow-capped mountains.
A large outdoor sculpture spelling 'SANTO TONE' with a cracked stone texture.
Hotel de Campo Colon

Hotel de Campo Colon

3.5 out of 5
Autopista Santa Fe - Rosario / KM 153 Santo Tomé Santa Fe
Book a stay at this spa hotel in Santo Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions April 15 Stadium and Museo De Arte Contemporaneo ...
8.4/10 Very Good! (51 reviews)
Hotel is OK, but not worth the price
"Pleasant and quiet rooms. Clean. But not a very friendly staff. The cafeteria has very few food/drink options, and it has a fly (the insect) problem. Oh, they overcharged my stay by 20% based on what Expedia quoted me, so read the bill before checking out..."

Reviewed on Feb 5, 2017

Get rates
Hotel de Campo Colon
InterTower Hotel

InterTower Hotel

4 out of 5
San Jeronimo 2779 Santa Fe Santa Fe
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $113 total per night from Dec 7 to Dec 8
$113 total
Dec 7 - Dec 8
Book a stay at this spa hotel in Santa Fe. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Museo Del Colegio De Medicos and Centro ...
InterTower Hotel
Los Silos Hotel

Los Silos Hotel

4 out of 5
Dique I Puerto Santa Fe Santa Fe Santa Fe
$129 nightly
The price is $129 total per night from Nov 15 to Nov 16
$129 total
Nov 15 - Nov 16
Book a stay at this spa hotel in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Ribera Shopping and Museo Del Colegio De Medicos ...
9.4/10 Exceptional! (36 reviews)
"Me gustó las personas que atienden. Todos muy buenos y dedicados a su trabajo."

Reviewed on Aug 24, 2026

Los Silos Hotel
See all 65 properties in Santo Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Agustín 1 Apart

Agustín 1 Apart

3.5 out of 5
130 Gral. Pedro Ferré Parana Entre Ríos
Stay at this apartment in Parana. Enjoy free WiFi, parking (surcharge), and onsite spa services. Popular attractions Plaza de Mayo and Museu De Sitio are located ...
9.2/10 Wonderful! (7 reviews)
"Nice and clean - neighbourhood residential but close to center of town. 30mins drive from Santa Fe"

Reviewed on Sep 25, 2026

Agustín 1 Apart
Apartment in Puerto Amarras

Apartment in Puerto Amarras

Santa Fe de la Vera Cruz Santa Fe
Stay at this apartment in Santa Fe. Enjoy laundry facilities and air conditioning. Popular attractions Ribera Shopping and Museo Del Colegio De Medicos are located ...
Apartment in Puerto Amarras
Mar de Sueños Parque Acuático Infantil

Mar de Sueños Parque Acuático Infantil

3 out of 5
Basani y Bustis Parana Entre Rios
Stay at this cabin in Parana. Enjoy free WiFi, free parking, and 4 outdoor pools. Popular attractions Museu De Sitio and Professor Antonio Serrano Museum of ...
8/10 Very Good! (1 review)
"En general la estadía fue buena, muy atento el personal, básicas pero lindas y limpias las cabañas. Me costo encontrar el lugar, recomiendo guardar las coordenadas para el GPS"

Reviewed on Nov 20, 2018

Mar de Sueños Parque Acuático Infantil
See all properties in Santo Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santo Tomé attractions

El Museo Etnografico y Colonial Juan de Garay

You can spend time exploring the galleries in El Museo Etnografico y Colonial Juan de Garay during your travels in Santo Tomé. Experience the area's live music and museums.
See properties

Frequently asked questions

Is Santo Tomé worth visiting?
Santo Tomé is worth visiting for its rich cultural scene, featuring attractions like El Museo Etnografico y Colonial Juan de Garay and Museo De Arte Contemporaneo. Travelers can also savor diverse European and Latin American dining, with many local flavors to explore.
When is the best time to visit Santo Tomé?
The best time to visit Santo Tomé is from May through September, when the climate is generally pleasant for travelers. For fewer crowds and potentially better value, the quieter month of January is a good option, as it falls within the warmer season.
What is Santo Tomé known for?
Santo Tomé is known for being named after Thomas the Apostle. This city in Argentina offers travelers cultural insights through its institutions, including El Museo Etnografico y Colonial Juan de Garay and Museo De Arte Contemporaneo.
What is a good itinerary length for Santo Tomé?
A good itinerary length for Santo Tomé is one to two days to explore attractions like El Museo Etnografico y Colonial Juan de Garay and Museo De Arte Contemporaneo. An extended stay of three to four days allows travelers to more deeply experience the local culture and cuisine, including European, Latin American, and Italian influences.
What are the top things to do in and around Santo Tomé?
In Santo Tomé, explore cultural and historical insights through its museums:

  • Visit El Museo Etnografico y Colonial Juan de Garay to delve into ethnographic and colonial history.
  • Explore Museo De Arte Contemporaneo for a look at contemporary art.

What cuisines can you find in Santo Tomé?
In Santo Tomé you can find Spanish cuisine, with popular dishes like paella, savory tapas, and sweet churros. Travelers can also enjoy South American and Italian options, alongside steakhouses and a variety of Asian dishes.
Can I book a refundable hotel in Santo Tomé?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santo Tomé by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santo Tomé with Expedia?
Expedia makes it easier to plan your Santo Tomé trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santo Tomé?
The best choice depends on your travel style. Hotels in Santo Tomé can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santo Tomé trip on Expedia?
Once you've booked your Santo Tomé trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santo Tomé trip?
Expedia offers customer support before, during, and after your Santo Tomé trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santo Tomé?
If it's your first trip to Santo Tomé, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santo Tomé hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santo Tomé hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Santo Tomé

A cityscape with a prominent historical building in the center, surrounded by modern high-rise buildings and a river in the background.

Santa Fe

Explore a world of travel with Expedia