Serena del Mar Vacations from $757

Book a Hotel + Flight or Car together to unlock savings

The Latest Serena del Mar Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Boutique Patio Corao By GEH Suites
Luxury Apartment– Private Pool & Rooftop Jacuzzi
Casa Bali Castillo View Private Pool & R
La Muralla Rooftop Duplex Jacuzzi & View
Casa Pestagua Relais Châteaux

Where to stay in Serena del Mar

Find the best Serena del Mar areas and neighborhoods for the activities you enjoy most. Learn more about Serena del Mar

Serena del Mar Hotel Deals

OZ Hotel Collection

OZ Hotel Collection

4.5 out of 5
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $99 total per night from Nov 16 to Nov 17
$99 total
Nov 16 - Nov 17
9.6/10 Exceptional! (873 reviews)
"The hotel was close to everything is was walking distance,I loved this place , all the staff was so nice."

Reviewed on Nov 10, 2026

OZ Hotel Collection
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

4 out of 5
Anillo Vial, Km 12, between Manzanillo Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$290 nightly
The price is $290 total per night from Nov 11 to Nov 12
$290 total
Nov 11 - Nov 12
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
Osh Hotel Cartagena

Osh Hotel Cartagena

4.5 out of 5
Calle 31 10 77 - Getsemaní Cartagena Bolivar
$238 nightly
The price is $238 total per night from Nov 24 to Nov 25
$238 total
Nov 24 - Nov 25
9.6/10 Exceptional! (1,194 reviews)
"Excelente"

Reviewed on Nov 9, 2026

Osh Hotel Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.