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Recommended hotels in Southeast Missouri

9.6 out of 10, Exceptional, (217)
$143 nightly
The price is $152
Dec 23 - Dec 24
Total with taxes and fees

9.4 out of 10, Exceptional, (1008)
$90 nightly
The price is $103
Dec 26 - Dec 27
Total with taxes and fees

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1007)
$90 nightly
The price is $102
Dec 28 - Dec 29
Total with taxes and fees

8.8 out of 10, Excellent, (705)
$110 nightly
The price is $124
Dec 31 - Jan 1, 2026
Total with taxes and fees

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (542)
$87 nightly
The price is $100
Dec 25 - Dec 26
Total with taxes and fees

9.2 out of 10, Wonderful, (968)
$106 nightly
The price is $120
Dec 27 - Dec 28
Total with taxes and fees

8.8 out of 10, Excellent, (463)
$76 nightly
The price is $86
Jan 1 - Jan 2, 2026
Total with taxes and fees
$107 nightly
The price is $121
Dec 23 - Dec 24
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Holiday Inn Poplar Bluff by IHG
10/10 Excellent
Find out more about Southeast Missouri
Southeast Missouri Condo Rentals information
Number of reviews | 13,153 |
|---|---|
Accommodation | 1 Condo Rentals |
Lowest Price | $60 |
Highest Price | $152 |
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