Perryville, MO

Travel Guide

Arched train bridge
Arched train bridge
A ferry carries cars across the Mississippi River from Missouri to Illinois and autumn rural countryside landscape with trees with colorful fall leaves on a hillside.
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
$91 nightly
The price is $104 total per night from Feb 15 to Feb 16
$104 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (557 reviews)
Very nice and clean hotel, and I slept very well. The room was comfortable and quiet. The only area for improvement would be the staff interaction. They didn’t greet me when I came in or out and seemed a bit annoyed, which made the experience feel less welcoming. Breakfast was also disappointing. ...

Reviewed on Jan 19, 2026

Holiday Inn Express & Suites Perryville by IHG
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
$70 nightly
The price is $80 total per night from Mar 2 to Mar 3
$80 total
Mar 2 - Mar 3
Total with taxes and fees
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (952 reviews)
If you're looking for a great deal, this is it. Unlike many less expensive hotels, this one has been refreshed with new carpeting and paint. Staff was courteous and friendly.

Reviewed on Feb 3, 2026

Super 8 by Wyndham Perryville
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
$73 nightly
The price is $84 total per night from Feb 8 to Feb 9
$84 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (420 reviews)
Great people there

Reviewed on Jan 29, 2026

Days Inn by Wyndham Perryville
See all 163 properties in Perryville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Perryville MO
Stay at this cabin in Perryville. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions County Lake State Wildlife Management Area ...
9.8/10 Exceptional! (9 reviews)
Host was super helpful and the stay was top notch. What a unique old home to get to stay in!

Reviewed on Jan 8, 2026

Hot Tub & Creek Views: Secluded Perryville Cabin
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona IL
Stay at this vacation home in Pomona. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Pomona Winery and Von Jakob Winery & Brewery are located ...
9.8/10 Exceptional! (62 reviews)
The property was secluded, clean and everything we wanted. Host was amazing and got back to us when needed. We came to just get away and it was perfect. No one close to the property. I don’t think we even heard another car while at the house.

Reviewed on Dec 28, 2025

Beautiful location in the secluded woods
"Little Brick House on Main (1865)”

"Little Brick House on Main (1865)”

Ste. Genevieve MO
Stay at this vacation home in Ste Genevieve. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions Felix Valle House State Historic ...
10/10 Exceptional! (65 reviews)
Great, cute place conveniently located. Thoughtfully designed with everything we needed.

Reviewed on Jan 18, 2026

"Little Brick House on Main (1865)”
See all properties in Perryville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

National Shrine of Our Lady of the Miraculous Medal

4.5/5(9 reviews)

Find out about the history of Perryville when you take a trip to National Shrine of Our Lady of the Miraculous Medal. Take in the festivals while you're in the area.

National Shrine of Our Lady of the Miraculous Medal

Perryville Country Club

3.5/5(4 reviews)

Enjoy a round of golf in Perryville at Perryville Country Club. Take in the festivals while you're in the area.

Perryville Country Club

County Lake State Wildlife Management Area

Explore the great outdoors at County Lake State Wildlife Management Area, a lovely green space in Perryville. Amble around the area's parks or experience its festivals.

County Lake State Wildlife Management Area

Saint Marys Lake

Commune with nature and explore the great outdoors at Saint Marys Lake during your travels in Perryville. Amble around the area's parks or experience its festivals.

Saint Marys Lake

James M. Eddleman Millitary Museum

You can spend an afternoon exploring the galleries in James M. Eddleman Millitary Museum during your travels in Perryville. Amble around the area's parks or experience its festivals.

James M. Eddleman Millitary Museum

Perry County Memorial Hospital

Though Perry County Memorial Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Perryville while you are here.

Perry County Memorial Hospital

Cities near Perryville

Castor River Shut-Ins Fredericktown Missouri Ozarks

Fredericktown

View of a serene sunset over the Mississippi River with a bridge and a boat, Chester, United States.

Chester

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