
Southern Louisiana Vacations from $547
Book a Hotel + Flight or Car together to unlock savings
Your Southern Louisiana Vacation
Choose a vacation package to Southern Louisiana and make planning your adventure quick and easy. With the finer details arranged before you leave, you can focus on enjoying every moment in this amazing destination. Your trip to Southern Louisiana wouldn't be complete without exploring some of its most renowned cities, starting with Lake Charles. Two of the top attractions here include Golden Nugget and Horseshoe Lake Charles Casino. Lafayette is another favorite with Southern Louisiana travelers. Visitors to this city enjoy Acadian Village and CIty Club at River Ranch. Expedia has everything you need for planning your Southern Louisiana vacation. From flights and hotels, to rental cars and more, we're here to help you curate a travel experience like no other.
The Latest Southern Louisiana vacation packages


Site 61 Guesthouse
Reviewed on Jul 27, 2026

Melrose Mansion
Reviewed on Nov 15, 2026


Trident Inn & Suites, New Orleans
Reviewed on Nov 15, 2026
Where to stay in Southern Louisiana

Downtown Lafayette
If you're spending some time in Downtown Lafayette, The Acadiana Center for the Arts and Cathedral of St John are top sights worth seeing.
Stay near popular Southern Louisiana attractions
Southern Louisiana Hotel Deals

L'Auberge Casino Resort Lake Charles

Golden Nugget Lake Charles

DoubleTree by Hilton Hotel Lafayette
Find the Best Southern Louisiana Vacation Packages
Southern Louisiana Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Louis Armstrong New Orleans Intl. Airport (MSY) |
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
- Lazy River in Southern Louisiana
- Cabins in Southern Louisiana
- Hotels in Rayne
- Motel 6 Hotels in Duson
- 2 Star Hotels in Southern Louisiana
- Romantic in Southern Louisiana
- Cottages in Southern Louisiana
- OYO Rooms Hotels in Southern Louisiana
- Hotels in Duson
- 4 Star Hotels in Lafayette
- Hotels in Scott
- Private Vacation Homes in Rayne
- Hotels in Crowley
- Hotels in Lafayette
- Downtown Lafayette Hotels
- Flights to Southern Louisiana
- Flights from New Orleans (MSY) to Lafayette (LFT)
- Delta Air Lines Atlanta (ATL) to Lafayette (LFT) flights
- Flights to Rayne
- Flights from Dallas (DFW) to Lafayette (LFT)
- American Airlines Dallas (DFW) to Lafayette (LFT) flights
- Flights to Lafayette
- Flights to Crowley
- Flights to Scott
- Flights to West Lafayette
- Southern Louisiana All Inclusive Vacation Packages
- Acadian Village
- Visit Southern Louisiana
- Where to stay in Lafayette
- Southern Louisiana All Inclusive Vacation Packages
- Visit Crowley
- Where to stay in Southern Louisiana
- Lafayette Vacations
- Visit Lafayette
- Maurice Vacations
- Where to stay in Breaux Bridge
- Visit Duson
- Frem Boustany Convention Center at The Heymann Center
- Where to stay in Palmetto Island State Park
- Visit Rayne
- Galeries Lafayette Shopping Center
- Where to stay in New Iberia
- Vermilionville
- Visit River Ranch
- Where to stay in Eunice
- Sunset Vacations
- Avery Island Vacations
- Kaplan Vacations
- New Iberia Vacations
- Crowley Vacations
- Scott Vacations
- Sterling Grove Historic District Vacations
- Southern Louisiana All Inclusive Vacation Packages
- Southern Louisiana All Inclusive Vacation Packages
- Southern Louisiana All Inclusive Vacation Packages
- Southern Louisiana All Inclusive Vacation Packages
- Southern Louisiana All Inclusive Vacation Packages
- Visit Breaux Bridge
- Where to stay in West Lafayette
- Southern Louisiana All Inclusive Vacation Packages
- Visit New Iberia
- Where to stay in Kinder
- Southern Louisiana All Inclusive Vacation Packages
- Visit Eunice
- Where to stay in Marsh Island
- Southern Louisiana All Inclusive Vacation Packages
- Visit Abbeville
- Where to stay in Schooner Island
- Southern Louisiana All Inclusive Vacation Packages
- Visit Kaplan
- Southern Louisiana All Inclusive Vacation Packages
- Visit Opelousas
- Southern Louisiana All Inclusive Vacation Packages
- Advantage Rent-A-Car Rental Cars in Southern Louisiana
- Van Car Rentals in Lafayette
- Rent A Wreck Rental Cars in Southern Louisiana
- Car rentals in Rayne
- Luxury Car Rentals in Lafayette
- Enterprise Rental Cars in Rayne
- Car rentals in Crowley
- Car rentals in Lafayette
- Car rentals in Duson
- Car rental Airport (LFT)
























