Santa Lucia
Syracuse
Visit Santa Lucia
Stay near popular Santa Lucia attractions
Things to do
Syracuse: Ortigia Island and Sea Caves Boat Tour
$22
per adult
Boat tour of Ortigia Island and sea caves
$22
per adult
90% of travellers recommend
Siracusa: Ortygia Island Boat Tour with Grotto Visit
$28
per adult
Boat tour Ortigia, sea caves and Pillirina 2h
$45
per adult
100% of travellers recommend
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
$45
per adult
Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves
$34
per adult
100% of travellers recommend
Santa Lucia Hotel Deals
Grande Albergo Alfeo
Via Nino Bixio 5 Syracuse SR
$68 nightly
The price is $78 total per night from Nov 21 to Nov 22
$78 total
Nov 21 - Nov 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and room service. Popular attractions Syracuse Forum Ruins and Santa ...
8.6/10 Excellent! (717 reviews)
"Beautiful and spacious room in a historic hotel. Breakfast buffet was delicious. Also a shout out to the excellent and thorough cleaning staff. We enjoyed our stay. The hotel was ideally located and we were able to walk to all the major spots in Palermo."
Reviewed on Nov 10, 2026
Hotel Palazzo Cavalieri
42 Via Malta Syracuse SR
$77 nightly
The price is $88 total per night from Nov 20 to Nov 21
$88 total
Nov 20 - Nov 21
Total with taxes and fees
Stay at this hotel in Syracuse. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Santa Lucia Bridge and Syracuse Forum Ruins ...
Nostos rooms & Apartments
Corso Umberto I, 66 Syracuse SR
$49 nightly
The price is $56 total per night from Nov 18 to Nov 19
$56 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this B&B in Syracuse. Enjoy free WiFi, valet parking (surcharge), and an airport shuttle (surcharge). Popular attractions Santa Lucia Bridge and Syracuse ...
9/10 Wonderful! (303 reviews)
"Room is very clean，Staff is very nice，Location is the best，parking is easy"
Reviewed on Nov 9, 2026
Fortaleza Charme House
Via Eritrea 6 Syracuse SR
$178 nightly
The price is $203 total per night from Nov 17 to Nov 18
$203 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this guesthouse in Syracuse. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Santa Lucia Bridge and Antico ...
10/10 Exceptional! (45 reviews)
"The hotel is quite cool - looks unimpressive from the outside but inside the rooms are very modern and clean. We had 2 rooms on the top floor with skylights which had remote-controlled shades. We were given code access to get in - which was perfect as we arrived early and dropped our bags off. We ..."
Reviewed on Oct 10, 2026
Caportigia Boutique Hotel
Viale Montedoro 76 Syracuse SR
$127 nightly
The price is $151 total per night from Nov 19 to Nov 20
$151 total
Nov 19 - Nov 20
Total with taxes and fees
Book a stay at this luxury hotel in Syracuse. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (303 reviews)
"Staff seemed very confused by every question. Clean room and bathroom."
Reviewed on Nov 14, 2026
Hotel Mediterraneo
Via Tripoli, 40 Syracuse SR
$50 nightly
The price is $57 total per night from Nov 16 to Nov 17
$57 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Syracuse. Enjoy room service, an airport shuttle (surcharge), and daily housekeeping. Popular attractions Syracuse ...
7.8/10 Good! (127 reviews)
"Very clean, well run and a decent breakfast. In a way it’s the perfect location: a 10-minute walk to Ortigia, but you are away from the over-touristy bits."
Reviewed on Oct 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Lucia
Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
Ortigia
Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.
Photo by William Keller
Open Photo by William Keller
Neapolis
While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.
Grottasanta
Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.
Tiche
Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.
Acradina
You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.