Santa Lucia
Syracuse
Visit Santa Lucia
Stay near popular Santa Lucia attractions
Things to do
Siracusa: Ortygia Island Boat Tour with Grotto Visit
$29
per adult
Syracuse: Ortigia Island and Sea Caves Boat Tour
$23
per adult
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
$46
per adult
Syracuse: Coast and Sea Caves Full Transparent Boat Tour
$23
per adult
Syracuse: Ortigia Island & Sea Cave Boat Tour with Prosecco
$23
per adult
Syracuse: Ortigia Boat Trip with Caves and Pillirina
$46
per adult
Santa Lucia Hotel Deals
Grande Albergo Alfeo
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Nov 19 to Nov 20
$72 total
Nov 19 - Nov 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and room service. Popular attractions Syracuse Forum Ruins and Santa ...
8.6/10 Excellent! (709 reviews)
"Very noisy on the weekends. Restaurants and bars across the road were lively until 4:00 am. Hotels is tired looking."
Reviewed on Oct 20, 2026
Hotel Palazzo Cavalieri
42 Via Malta Syracuse SR
$69 nightly
The price is $78 total per night from Nov 16 to Nov 17
$78 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this hotel in Syracuse. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Santa Lucia Bridge and Syracuse Forum Ruins ...
9/10 Wonderful! (50 reviews)
"Very responsive staff that helped me organize transportation to and from the airport, accommodation for my baby, and a surprise welcome for my wife’s birthday. Amazing location just outside Ortigia, I honestly preferred staying there than on the island. Highly recommended."
Reviewed on Oct 1, 2026
Caportigia Boutique Hotel
Viale Montedoro 76 Syracuse SR
$136 nightly
The price is $161 total per night from Nov 20 to Nov 21
$161 total
Nov 20 - Nov 21
Total with taxes and fees
Book a stay at this luxury hotel in Syracuse. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (300 reviews)
"Overall the hotel was very nice and in perfect location. We would definitely stay again. Some items they could improve. The reading lights above bed did not work and there was no other source of light except the huge lights for the entire room. The shower floor was super super super slippery. Both ..."
Reviewed on Sep 28, 2026
Nostos rooms & Apartments
Corso Umberto I, 66 Syracuse SR
$57 nightly
The price is $64 total per night from Nov 17 to Nov 18
$64 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this B&B in Syracuse. Enjoy free WiFi, valet parking (surcharge), and an airport shuttle (surcharge). Popular attractions Santa Lucia Bridge and Syracuse ...
Fortaleza Charme House
Via Eritrea 6 Syracuse SR
$145 nightly
The price is $165 total per night from Nov 10 to Nov 11
$165 total
Nov 10 - Nov 11
Total with taxes and fees
Stay at this guesthouse in Syracuse. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Santa Lucia Bridge and Antico ...
10/10 Exceptional! (45 reviews)
"The hotel is quite cool - looks unimpressive from the outside but inside the rooms are very modern and clean. We had 2 rooms on the top floor with skylights which had remote-controlled shades. We were given code access to get in - which was perfect as we arrived early and dropped our bags off. We ..."
Reviewed on Oct 10, 2026
Hotel Mediterraneo
Via Tripoli, 40 Syracuse SR
$71 nightly
The price is $81 total per night from Oct 29 to Oct 30
$81 total
Oct 29 - Oct 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Syracuse. Enjoy room service, an airport shuttle (surcharge), and daily housekeeping. Popular attractions Syracuse ...
7.8/10 Good! (126 reviews)
"Very clean, well run and a decent breakfast. In a way it’s the perfect location: a 10-minute walk to Ortigia, but you are away from the over-touristy bits."
Reviewed on Oct 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Lucia
Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
Ortigia
Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.
Grottasanta
Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.
Photo by William Keller
Open Photo by William Keller
Neapolis
While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.
Tiche
Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.
Acradina
You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.
