Tupile Vacations from $453

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

The Latest Tupile vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Save 100% on your flight
per person
Oct 22 - Oct 26
found 2 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.4/10 Exceptional! (111 reviews)
The grounds where beautiful and the staff was so friendly.

Reviewed on Jul 19, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
per person
Oct 29 - Nov 2
found 23 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
No reviews
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Oct 15 - Oct 22
found 22 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (965 reviews)
I like the breakfast style and everything was near by the hotel. I didn’t like the early morning noise. It was just a little bit noisy. Not a big deal.

Reviewed on Aug 14, 2025

Casa Fofo Family House

Casa Fofo Family House

3 out of 5
Save 100% on your flight
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Don't see what you're looking for?
See all available trips from Columbus to Tupile
View all trips

Discover the most popular places to visit in Tupile

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals.

Museum of the Kuna Nation

Porvenir Museum

You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.

Porvenir Museum

What to do in Tupile

San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool

San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool

$76
per adult
San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool
Overnight in San Blas - Private Room + Meals + Boat Tour

Overnight in San Blas - Private Room + Meals + Boat Tour

$160
per adult
Overnight in San Blas - Private Room + Meals + Boat Tour
Discover the San Blas Islands in one day

Discover the San Blas Islands in one day (3 islands)

$71
per adult
Discover the San Blas Islands in one day (3 islands)
See all activities in Tupile

Tupile Hotel Deals

San Blas Tour Aridub

San Blas Tour Aridub

2 out of 5
Urgandi, Guna Yala, Panamá, Narganá, Guna Yala
$131 nightly
The price is $144 total per night from Aug 15 to Aug 16
$144 total
Aug 15 - Aug 16
Total includes taxes and fees
San Blas Tour Aridub
San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin

2.5 out of 5
C5W9 4M Nusatupo, Narganá, Guna Yala
$359 nightly
The price is $385 total per night from Aug 15 to Aug 16
$385 total
Aug 15 - Aug 16
Total includes taxes and fees
San Blas Private Oceanfront Cabin
San Blas Private Over-the-Water Cabin

San Blas Private Over-the-Water Cabin

2.5 out of 5
Nusatupo, Narganá, Guna Yala
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling ..."

Reviewed on Oct 27, 2022

Get rates
San Blas Private Over-the-Water Cabin
See all 15 properties in Tupile
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Tupile vacation package cost?
You'll find cheap prices from $453 on Expedia for your Tupile break. However, a range of factors like your choice of hotel, the season and length of stay will determine how much your vacation to Tupile costs.
What are the cheapest months to go to Tupile?
May, June and July are great times to search for cheap Tupile vacation packages. Opting to travel in quieter months means you'll typically find lower prices on flights and hotels.
How many days is enough for Tupile?
The ideal duration of your Tupile vacation depends on what you'd like to do and see. Typically, a handful of days to a week will give you plenty of time to tick off all the main sights and explore some hidden treasures along the way.
How to find the best Tupile package deals?
Use Expedia's filters to help you find some unbeatable Tupile package deals. When you begin your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for Tupile package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Tupile vacation as a package?
An Expedia vacation package could land you considerable savings when compared to arranging stays and flights separately. Better still, you can customize your Tupile trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Tupile?
If you're planning an impromptu Tupile vacation, browse our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can land sensational deals on your hotels and flights by booking well in advance.
How to plan a trip to Tupile?

  1. Pick the best time to travel: Your schedule, favorite season and the type of weather you enjoy can all influence your decision on when to travel to Tupile.
  2. Work out your budget: Ensure you have enough money to pay for everything from meals and transportation to activities and airfares. Your hotel will likely be the largest expense during your trip to Tupile.
  3. Discover Tupile using Expedia's trip planning tool: Gain insights into the most popular attractions and best properties for your trip to Tupile. You can also save your favorite locations, collaborate with your group and organize your plans in one place.
  4. Decide your trip length: Consider how much time you'd like to spend discovering Tupile. Plan your days so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  5. Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left is to pick a Tupile vacation package that brings all your bookings together.
  6. Book experiences or activities in advance: Whether it's a ticket to a big attraction or a day trip, you won't have to worry about missing out on Tupile's best offerings. Find all the fun things to do in Tupile with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later Tupile vacation packages?
Your Tupile getaway should be an escape from your busy life, not a reason for money worries. So to give you a little more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the total cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.