Uptown - Upper Duval Vacations from $665

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Your Uptown - Upper Duval Vacation

Take the hassle out of planning your next escape by booking an Uptown - Upper Duval vacation package. Immerse yourself in the sights and sounds of this unique neighborhood and enjoy what it has to offer. Some leading nearby attractions to check out during your trip to Uptown - Upper Duval include Ernest Hemingway Home and Museum, Audubon House and Tropical Gardens and Mallory Square. No matter your travel plans or the size of your budget, booking the ultimate Uptown - Upper Duval vacation is simple with Expedia.

The Latest Uptown - Upper Duval Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Vacation Club at Beach House, Key West
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The Perry Hotel & Marina Key West
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Where to stay in Uptown - Upper Duval

Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
Fully refundable
$229 nightly
The price is $258 total per night from Sep 11 to Sep 12
$258 total
Sep 11 - Sep 12
Total with taxes and fees
8.6/10 Excellent! (2,701 reviews)
"Out dated."

Reviewed on Aug 24, 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street, Key West, FL
Fully refundableReserve now, pay when you stay
$295 nightly
The price is $332 total per night from Sep 7 to Sep 8
$332 total
Sep 7 - Sep 8
Total with taxes and fees
8.4/10 Very Good! (1,011 reviews)
"The Reach Hilton Resort was excellent. The staff was professional and took care of our every need. The location was accessible to everywhere we wanted to go whether it was by walking or a quick uber ride. Even with only one working elevator at times we hardly had to wait. We would definitely stay ..."

Reviewed on Aug 24, 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street, Key West, FL
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $165 total per night from Sep 11 to Sep 12
$165 total
Sep 11 - Sep 12
Total with taxes and fees
The Southernmost Inn - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Uptown - Upper Duval

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.