Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
4.5/5(3,246 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
4/5(999 reviews)
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
4.5/5(770 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
$42
per adult
94% of travellers recommend
Key West Sunset Sail with Live Music, Drinks and Appetizers!
$80
per traveler
92% of travellers recommend
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
$27
per adult
88% of travellers recommend
Miami to Key West Day Trip with Activity Options
$39
per adult
82% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
$55
per adult
88% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$330 nightly
The price is $372 total per night from May 19 to May 20
$372 total
May 19 - May 20
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,240 reviews)
The hotel has a wonderful location on the beach but is some distance from the bar and restaurant area. It is very expensive for the standard of the hotel at at $60 the resort fee is exorbitant as nothing is provided for it.
Reviewed on Apr 26, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
$239 nightly
The price is $269 total per night from Apr 27 to Apr 28
$269 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very Good! (1,335 reviews)
The place was nice and the coffee/happy hour were great. Only negative was there were a bunch of nails sticking up from the floor in my room and I ripped two separate socks.
Reviewed on Apr 25, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
$295 nightly
The price is $332 total per night from May 25 to May 26
$332 total
May 25 - May 26
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,005 reviews)
Friendly staff, room cleaning could have been better. Last two days of our stay there was no room cleaning performed. Did not know about the parking fees at the resort until we arrived. I may have overlooked that while reviewing the property while booking.
Reviewed on Apr 25, 2026
Southwinds Motel
1321 Simonton Street Key West FL
$223 nightly
The price is $251 total per night from Apr 27 to Apr 28
$251 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,319 reviews)
The room was clean but very small. The bathroom was tiny. I am 5’5” and not overweight and I could barely close the bathroom door when sitting on the toilet. Loud window air conditioner that did not cool that great. No headboard on the bed. They are close to duvall street and the beach. They will ...
Reviewed on Apr 25, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
$217 nightly
The price is $244 total per night from May 6 to May 7
$244 total
May 6 - May 7
Total with taxes and fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (366 reviews)
We loved staying at this super cute little resort within walking distance of everything. The pool was warm and the gardens pretty. Just note there’s only a few free parking spaces out front.
Reviewed on Apr 26, 2026
Santa Maria Suites
1401 Simonton St Key West FL
$449 nightly
The price is $505 total per night from May 25 to May 26
$505 total
May 25 - May 26
Total with taxes and fees
Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,000 reviews)
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Reviewed on Apr 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(229 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Bahama Village
5/5(39 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
4.5/5(4,090 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Florida Keys Beaches and Clarence S. Higgs Memorial Beach Park.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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