Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
$50
per adult
92% of travellers recommend
Key West Sunset Sail with Live Music, Drinks and Appetizers!
$80
per adult
92% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
$27
per adult
80% of travellers recommend
Miami to Key West Day Trip with Activity Options
$39
per adult
84% of travellers recommend
Lands End Sunset Cruise with Full Bar & Live Music
$75
per adult
90% of travellers recommend
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
$48
per adult
90% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Fully refundable
$242 nightly
The price is $272 total per night from Nov 30 to Dec 1
$272 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,833 reviews)
The room was clean, the staff so friendly.
Reviewed on Oct 30, 2025
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
$312 nightly
The price is $351 total per night from Nov 3 to Nov 4
$351 total
Nov 3 - Nov 4
Total with taxes and fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,007 reviews)
Great job
Reviewed on Oct 27, 2025
The Southernmost Inn - Adults Only
525 United Street, Key West, FL
$145 nightly
The price is $163 total per night from Nov 2 to Nov 3
$163 total
Nov 2 - Nov 3
Total with taxes and fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,169 reviews)
Great spot but the our bathroom was definitely dirty when we got in. 5 stars
Reviewed on Oct 29, 2025
Southwinds Motel
1321 Simonton Street, Key West, FL
$160 nightly
The price is $181 total per night from Nov 18 to Nov 19
$181 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,215 reviews)
I loved that you could get a daily pass to the beach for towels and chairs, they had laundry(free of charge) onsite that included the soap.
Reviewed on Oct 27, 2025
Orchid Key Inn - Adults Only
1004 Duval St, Key West, FL
$242 nightly
The price is $272 total per night from Nov 3 to Nov 4
$272 total
Nov 3 - Nov 4
Total with taxes and fees
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast and the pool in ...
9.8/10 Exceptional! (1,021 reviews)
Hotel. S right on the Wall Street walking distance from everything was able to rent a golf cart through the front desk, which I was able to park on property, was delivered and picked up at no extra charge.Very clean adult only property
Reviewed on Oct 28, 2025
Douglas House
419 Amelia St, Key West, FL
$195 nightly
The price is $219 total per night from Nov 2 to Nov 3
$219 total
Nov 2 - Nov 3
Total with taxes and fees
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...
9.6/10 Exceptional! (192 reviews)
We were greeted by a gentleman named Hamzi. All hotels should be lucky enough to have someone like him greeting guests. We were made to feel like he was welcoming us into his own home. Hats off to you, Hamzi. The grounds are unbelievably clean and peaceful. We will definitely return!!!
Reviewed on Oct 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(226 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
5/5(38 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
Key West Historic District
4.5/5(4,033 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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