Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
4.5/5(3,246 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
4/5(999 reviews)
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
4.5/5(770 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
$42
per adult
94% of travellers recommend
Key West Sunset Sail with Live Music, Drinks and Appetizers!
$80
per traveler
92% of travellers recommend
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
$27
per adult
88% of travellers recommend
Miami to Key West Day Trip with Activity Options
$39
per adult
82% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
$55
per adult
88% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$316 nightly
The price is $356 total per night from May 28 to May 29
$356 total
May 28 - May 29
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,251 reviews)
The $65 a day add on fee was ridiculous but after speaking to manager it was refunded . Beach had a lot of grass but I think k it’s just grass season . Food was very good but pricy . Room was nice until u had to look behind the bed for a lost earring then it was not so nice . For the cost I would ...
Reviewed on Apr 27, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
$229 nightly
The price is $257 total per night from Apr 29 to Apr 30
$257 total
Apr 29 - Apr 30
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very Good! (1,338 reviews)
Great place.Great price. Quiet. Pools were awesome to relax in. Loved the free wine and cheese nightly and good breakfast that's included. Will be staying again
Reviewed on Apr 27, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
$329 nightly
The price is $370 total per night from May 11 to May 12
$370 total
May 11 - May 12
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,006 reviews)
Friendly staff, room cleaning could have been better. Last two days of our stay there was no room cleaning performed. Did not know about the parking fees at the resort until we arrived. I may have overlooked that while reviewing the property while booking.
Reviewed on Apr 25, 2026
Southwinds Motel
1321 Simonton Street Key West FL
$233 nightly
The price is $262 total per night from May 10 to May 11
$262 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,321 reviews)
Good location.
Reviewed on Apr 28, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
$227 nightly
The price is $255 total per night from May 25 to May 26
$255 total
May 25 - May 26
Total with taxes and fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (366 reviews)
We loved staying at this super cute little resort within walking distance of everything. The pool was warm and the gardens pretty. Just note there’s only a few free parking spaces out front.
Reviewed on Apr 26, 2026
Santa Maria Suites
1401 Simonton St Key West FL
$439 nightly
The price is $494 total per night from May 25 to May 26
$494 total
May 25 - May 26
Total with taxes and fees
Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,000 reviews)
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Reviewed on Apr 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(229 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Bahama Village
5/5(39 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
4.5/5(4,090 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Florida Keys Beaches and Clarence S. Higgs Memorial Beach Park.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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