Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
4.5/5(3,244 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
4/5(999 reviews)
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
4.5/5(770 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
$42
per adult
94% of travellers recommend
Miami to Key West Day Trip with Activity Options
$39
per adult
82% of travellers recommend
Key West Sunset Sail with Live Music, Drinks and Appetizers!
$80
per traveler
92% of travellers recommend
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
$27
per adult
88% of travellers recommend
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
$45
per adult
92% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
The price is $419 total per night from May 12 to May 13
$419 total
per night
May 12 - May 13
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,217 reviews)
Clean rooms and super friendly staff. Updated property. We got daily notifications about music and fun events happening. We traveled with my young daughter and the staff was all so sweet and fun with her. Great family spot!
Reviewed on Apr 13, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
The price is $370 total per night from May 3 to May 4
$370 total
per night
May 3 - May 4
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,009 reviews)
Pool and beach were great. Food and drink service right to your beach chair. Great views.
Reviewed on Apr 13, 2026
Southwinds Motel
1321 Simonton Street Key West FL
The price is $272 total per night from Apr 20 to Apr 21
$272 total
per night
Apr 20 - Apr 21
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,306 reviews)
Nice place to stay, within 30 minute walk to all fun places in old Key West. Very weak water supply during our stay.
Reviewed on Apr 14, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
The price is $251 total per night from Apr 15 to Apr 16
$251 total
per night
Apr 15 - Apr 16
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,317 reviews)
Beautiful location, beautiful wine, and cheese happy hour and lovely staff
Reviewed on Apr 13, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
The price is $300 total per night from Apr 20 to Apr 21
$300 total
per night
Apr 20 - Apr 21
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (348 reviews)
Pool was nice, kitchen had everything you needed
Reviewed on Apr 13, 2026
Santa Maria Suites
1401 Simonton St Key West FL
The price is $561 total per night from May 11 to May 12
$561 total
per night
May 11 - May 12
Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,001 reviews)
Nice suites , staff very friendly. Conveniently located. Check your room bills carefully.
Reviewed on Apr 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(229 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Bahama Village
5/5(39 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
4.5/5(4,090 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Florida Keys Beaches and Clarence S. Higgs Memorial Beach Park.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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