Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Florida: Key West Overseas Highway App-Based Driving Audio Tour
$17
per traveler
80% of travellers recommend
Key West’s Old Town Treasures: A Self-Guided Audio Tour
$15
per adult
Florida Key West Self-Guided Walking Audio Tour Via App
$10
per traveler
Southernmost Key West History and Culture Small-Group Walking Tour
$40
per adult
An Audio Guide of Key West’s Journey From Village to Micro State
$12
per adult
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Fully refundable
$207 nightly
The price is $233 total per night from Sep 30 to Oct 1
$233 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,733 reviews)
"Wonderful!"
Reviewed on Sep 10, 2025
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
$250 nightly
The price is $282 total per night from Sep 25 to Sep 26
$282 total
Sep 25 - Sep 26
Total with taxes and fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,006 reviews)
"."
Reviewed on Sep 9, 2025
The Southernmost Inn - Adults Only
525 United Street, Key West, FL
$139 nightly
The price is $156 total per night from Sep 28 to Sep 29
$156 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,177 reviews)
Everything you need
"The property had everything you needed. Free (and very yummy) breakfast, pool and AC. The staff was very friendly and the property was well kept!"
Reviewed on Sep 8, 2025
Southwinds Motel
1321 Simonton Street, Key West, FL
$132 nightly
The price is $149 total per night from Sep 22 to Sep 23
$149 total
Sep 22 - Sep 23
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,171 reviews)
"the staff was so helpful the room was clean my husband met so many people at the local bar and he seen people he met the year before we try to stay in the same place ever year we will be coming back next year"
Reviewed on Sep 9, 2025
Santa Maria Suites
1401 Simonton St, Key West, FL
$247 nightly
The price is $278 total per night from Sep 18 to Sep 19
$278 total
Sep 18 - Sep 19
Total with taxes and fees
Stay at this 4-star resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. ...
9.6/10 Exceptional! (1,002 reviews)
"This property will not disappoint you. The rooms are spacious, clean, and have everything you would need..They have a full kitchen area ( dishes..pots and pans..coffee makers..blender..toaster..microwave..stove..oven..dishwasher..2 drawer refrigerator and 2 drawer freezer) 2 full bedrooms with king ..."
Reviewed on Sep 5, 2025
Kona Kai Oasis
630 South Street, Key West, FL
$107 nightly
The price is $120 total per night from Sep 24 to Sep 25
$120 total
Sep 24 - Sep 25
Total with taxes and fees
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (555 reviews)
"Not many towels and the fridge was dirty"
Reviewed on Sep 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(226 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
5/5(38 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
Key West Historic District
4.5/5(4,033 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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