Title: Visit Uptown - Upper Duval: 2026 Uptown - Upper Duval, Key West Travel Guide | Expedia.com [Hotels in Uptown - Upper Duval](https://expedia.com/Uptown-Upper-Duval-Key-West-Hotels.0-n553248635976473524-0.Travel-Guide-Filter-Hotels)[Flights to Key West](https://expedia.com/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.com/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Car Rentals in Uptown - Upper Duval](https://expedia.com/Car-Rentals-In-Uptown-Upper-Duval.d553248635976473524.Car-Rental-Guide)[Uptown - Upper Duval Vacations](https://expedia.com/Uptown-Upper-Duval.d553248635976473524.Destination-Travel-Guides) # Uptown - Upper Duval, FL ## Key West ![Uptown - Upper Duval](https://images.trvl-media.com/place/1187/48023594-76b8-4930-a4a9-06a0f12911a4.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Uptown - Upper Duval](https://images.trvl-media.com/place/1187/bf123656-e1f1-4311-8c95-2b851a4b8721.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Uptown - Upper Duval](https://images.trvl-media.com/place/1187/ca919e5f-361f-4129-b171-77d34c9b6791.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Uptown - Upper Duval](https://images.trvl-media.com/place/1187/5d488261-cf7f-43ce-a448-690eeb186cd2.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Uptown - Upper Duval](https://images.trvl-media.com/place/1187/c8f3d3ca-f3d1-4ec7-8539-65db27bcc943.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Uptown - Upper Duval Things to do Hotels Where to stay --- ### Popular places to visit ![Southernmost Point](https://images.trvl-media.com/place/501380/97e2b26c-38ce-483b-b59e-7a017404ab35.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Southernmost Point Snap a memorable photograph from the edge of North America at this monumental landmark. [](https://expedia.com/Southernmost-Point-Old-Town-Key-West.d501380.Vacation-Attraction) ![South Beach](https://images.trvl-media.com/place/6246827/42d13a3e-a933-4e9f-b857-cde9f4314a24.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### South Beach Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim. [](https://expedia.com/South-Beach-Old-Town-Key-West.d6246827.Vacation-Attraction) ![Key West Butterfly and Nature Conservatory](https://images.trvl-media.com/place/6068597/40321a43-d7c0-4ff6-bffa-8178a19d9be2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Key West Butterfly and Nature Conservatory With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West. [](https://expedia.com/Key-West-Butterfly-And-Nature-Conservatory-Old-Town-Key-West.d6068597.Vacation-Attraction) ### Things to do ![Key West: Shark and Wildlife Viewing Catamaran Tour](https://mediaim.expedia.com/localexpert/49301862/1f86e64a-bd95-4e62-b598-309a7a3d7dda.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Key West: Shark and Wildlife Viewing Catamaran Tour $99 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/key-west-shark-and-wildlife-viewing-catamaran-tour.a49301862.activity-details) ![Miami to Key West Day Trip with Activity Options](https://mediaim.expedia.com/localexpert/1344154/127def52-afdb-470f-97fc-ba484b15a753.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Miami to Key West Day Trip with Activity Options $39 per adult **82%** of travellers recommend [](https://expedia.com/things-to-do/miami-to-key-west-day-trip-with-activity-options.a1344154.activity-details) ![Key West Half-Day Fishing Charter](https://mediaim.expedia.com/localexpert/5299343/671745e1-9724-45ed-9f6d-20286eca548a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Key West Half-Day Fishing Charter $95 per adult **90%** of travellers recommend [](https://expedia.com/things-to-do/key-west-half-day-fishing-charter.a5299343.activity-details) ![Entertainer in character at the Shipwreck Treasure Museum in Key West](https://mediaim.expedia.com/localexpert/191533/0194ef1a-54dc-4244-9dae-801c2ad37537.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Shipwreck Treasure Museum Tickets $19 per adult **78%** of travellers recommend [](https://expedia.com/things-to-do/shipwreck-treasure-museum-tickets.a191533.activity-details) ![Sunset Dinner Cruise in Key West with Live Music & Unlimited Open Bar!](https://mediaim.expedia.com/localexpert/588408/c7a7cff0-8d80-4d7c-9dd4-6dd2dd79a519.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sunset Dinner Cruise in Key West with Live Music & Unlimited Open Bar! $76 per adult **88%** of travellers recommend [](https://expedia.com/things-to-do/sunset-dinner-cruise-in-key-west-with-live-music-unlimited-open-bar.a588408.activity-details) ![Passengers enjoying the shade on the Conch Tour Train in Key West](https://mediaim.expedia.com/localexpert/191535/9b448a2f-ece5-45c7-be77-f9172888dc8f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Key West Conch Tour Train $45 per adult **88%** of travellers recommend [](https://expedia.com/things-to-do/key-west-conch-tour-train.a191535.activity-details) [See all activities in Key West](https://expedia.com/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities) --- ## Uptown - Upper Duval Hotel Deals ![The Reach Key West, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/bc3021c3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Reach Key West, Curio Collection by Hilton 1435 Simonton Street Key West FL $391 nightly $440 total Apr 22 - Apr 23 Total with taxes and fees Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ... 8.6/10 Excellent! (1,002 reviews) The beach was perfect except when a wedding was going on it was limited and no warnings for this. There was only 1 waitress fir beach and pool orders. Also waitress didnt even knowledge us over 10 when we tried to go for breakfast so we left . The culture is wonderful except wasnt informed roosters ... Reviewed on Mar 29, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F22%2F2026&endDate=4%2F23%2F2026&selected=457821&PinnedHotelID=457821&HadPinnedHotel=true®ionId=553248635976473524) ![Southwinds Motel](https://images.trvl-media.com/lodging/9000000/8990000/8984500/8984451/45887e0a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Southwinds Motel 1321 Simonton Street Key West FL $320 nightly $360 total Apr 12 - Apr 13 Total with taxes and fees Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ... 8.6/10 Excellent! (1,295 reviews) Nice place. Laid back really liked it only problem is they charged me 3 days parking an extra vehicle but only parks 1 day even after i notified front desk. Reviewed on Mar 27, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=8984451&PinnedHotelID=8984451&HadPinnedHotel=true®ionId=553248635976473524) ![The Southernmost Inn - Adults Only](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/a8250942_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Southernmost Inn - Adults Only 525 United Street Key West FL $279 nightly $314 total Apr 1 - Apr 2 Total with taxes and fees Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ... [](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=4280752&PinnedHotelID=4280752&HadPinnedHotel=true®ionId=553248635976473524) ![Douglas House - Adults Only](https://images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/ba6b4821_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Douglas House - Adults Only 419 Amelia St Key West FL $346 nightly $389 total Apr 12 - Apr 13 Total with taxes and fees Stay at this guesthouse in Key West. Enjoy free WiFi, parking (surcharge), and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ... 9.6/10 Exceptional! (335 reviews) Jen at front reception was beyond gracious and kind. She went out of her way to mar us feel welcomed and took excellent care of our party during our entire stay. Pool area is well stocked, clean and lovely. Rooms are quiet! Location is convenient. Would recommend and stay again. Reviewed on Mar 29, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=110488130&PinnedHotelID=110488130&HadPinnedHotel=true®ionId=553248635976473524) ![Santa Maria Suites](https://images.trvl-media.com/lodging/1000000/920000/911000/910922/069776b3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Santa Maria Suites 1401 Simonton St Key West FL $619 nightly $696 total Apr 20 - Apr 21 Total with taxes and fees Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ... 9.6/10 Exceptional! (1,000 reviews) Rooms were very nice! Pool bar was a complete joke-(close at 6 pm, no food, no entertainment, no social gathering whatsoever) After a busy day with the kids- coming back to a “resort “ that has food, cocktails, a lil music, and good conversations while kids swim until hitting the sack- that’s how ... Reviewed on Mar 25, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F20%2F2026&endDate=4%2F21%2F2026&selected=910922&PinnedHotelID=910922&HadPinnedHotel=true®ionId=553248635976473524) ![Orchid Key Inn - Adults Only](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/adc3a7f1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Orchid Key Inn - Adults Only 1004 Duval St Key West FL $301 nightly $339 total Apr 5 - Apr 6 Total with taxes and fees Stay at this hotel in Key West. Enjoy free breakfast, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ... 9.8/10 Exceptional! (1,002 reviews) Had a fantastic stay at this lovely hotel! The staff was amazing and rooms were super clean. The breakfast was AMAZING, and great happy hour. Reviewed on Mar 30, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=809032&PinnedHotelID=809032&HadPinnedHotel=true®ionId=553248635976473524) [See all 2,661 properties in Uptown - Upper Duval](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026®ionId=553248635976473524) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Uptown - Upper Duval hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=2026-03-30&endDate=2026-03-31)[Mar 30 - Mar 31](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=2026-03-30&endDate=2026-03-31) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=2026-03-31&endDate=2026-04-01)[Mar 31 - Apr 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=2026-03-31&endDate=2026-04-01) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=4%2F10%2F2026&endDate=4%2F12%2F2026)[Apr 10 - Apr 12](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976473524&startDate=4%2F10%2F2026&endDate=4%2F12%2F2026) --- ### Other neighborhoods around Uptown - Upper Duval ![Old Town Key West](https://images.trvl-media.com/place/553248635976481920/c3895c9f-e471-4c93-ac2e-85c99f8f8fec.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Old Town Key West 4.5/5(229 area reviews) Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area. [](https://expedia.com/Key-West-Old-Town-Key-West.dx553248635976481920) ![Bahama Village](https://images.trvl-media.com/place/6068605/e209543d-9f52-46a8-b0de-136d3f268be5.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Bahama Village 5/5(39 area reviews) Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum. [](https://expedia.com/Key-West-Bahama-Village.dx553248621533115696) ![Downtown Key West](https://images.trvl-media.com/place/6068616/ac9e1424-8949-4483-8a12-9063d1511aa2.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Key West If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing. [](https://expedia.com/Key-West-Downtown-Key-West.dx553248635976470405) ![Key West Historic District](https://images.trvl-media.com/place/6068599/e22dc889-0174-435e-9d9b-302d362fd045.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Key West Historic District 4.5/5(4,090 area reviews) Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district. [](https://expedia.com/Key-West-Key-West-Historic-District.dx6281809) ![Casa Marina](https://images.trvl-media.com/place/1187/d0c11bd8-7e39-4ed6-b09c-d3007de4fe5e.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Casa Marina While visiting Casa Marina, you might make a stop by sights like Florida Keys Beaches and Clarence S. Higgs Memorial Beach Park. [](https://expedia.com/Key-West-Casa-Marina.dx864981993084186624) ![St. Paul's Episcopal Church, Key West ](https://images.trvl-media.com/place/553248635976482119/ebe24c59-9ab8-4963-a531-5638939859c3.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### White Street Gallery District When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area. [](https://expedia.com/Key-West-White-Street-Gallery-District.dx553248635976482119) [See our Where To Stay guide](https://expedia.com/Key-West.dx1187.Where-To-Stay?rfrr=TG.LP.Dest.Neigh.Neighborhoods) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Uptown - Upper Duval, FL ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Key West Hotels ](https://www.expedia.com/Key-West-Hotels.d1187.Travel-Guide-Hotels) - [All-Inclusive Resorts in Key West ](https://www.expedia.com/Key-West-Hotels-All-Inclusive-Hotel.0-0-d1187-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Key West ](https://www.expedia.com/Key-West-Hotels-Cheap-Hotels.0-0-d1187-tCheapHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Key West ](https://www.expedia.com/Key-West-Hotels-Oceanfront-Hotels.0-0-d1187-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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[Hotels near Key West Lighthouse and Keeper's Quarters Museum ](https://www.expedia.com/Key-West-Lighthouse-And-Keepers-Quarters-Museum-Hotels.0-l501383-0.Travel-Guide-Filter-Hotels) - [Hotels near MLK Community Pool & Community Center ](https://www.expedia.com/MLK-Community-Pool-Community-Center-Hotels.0-l553248621532652610-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Key West ](https://www.expedia.com/4Star-Key-West-Hotels.s40-0-d1187.Travel-Guide-Filter-Hotels) - [Hotels near South Beach ](https://www.expedia.com/South-Beach-Hotels.0-l6246827-0.Travel-Guide-Filter-Hotels) - [Hotels near Downtown Key West ](https://www.expedia.com/Downtown-Key-West-Key-West-Hotels.0-n553248635976470405-0.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Key West ](https://www.expedia.com/Key-West-Hotels-Hilton-Hotels.0-0-d1187--bHiltonHotels.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Key West ](https://www.expedia.com/5Star-Key-West-Hotels.s50-0-d1187.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts & in Key West ](https://www.expedia.com/Key-West-Hotels-Honeymoon-Hotels.0-0-d1187-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - 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