Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Stay near popular Uptown - Upper Duval attractions
Things to do
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
$69
per adult
88% of travellers recommend
Shipwreck Treasure Museum Tickets
$19
per adult
80% of travellers recommend
Key West Dolphin Watch & Snorkel Combo With Unlimited Beer & Wine
$55
per adult
92% of travellers recommend
Sunset Sail in Key West with Beverages Included
$79
per adult
98% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$225 nightly
The price is $253 total per night from Sep 29 to Sep 30
$253 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,607 reviews)
"Todo estaba perfecto menos la playa estaba extremadamente sucia"
Reviewed on Sep 22, 2026
Southwinds Motel
1321 Simonton Street Key West FL
$155 nightly
The price is $174 total per night from Sep 23 to Sep 24
$174 total
Sep 23 - Sep 24
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,382 reviews)
"The room was clean and the staff very helpful"
Reviewed on Sep 21, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
Fully refundable
$243 nightly
The price is $273 total per night from Sep 30 to Oct 1
$273 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,029 reviews)
"The facility was clean and well Maintained. The personnel were helpful and kind. I would recommend this resort to all friends and family."
Reviewed on Sep 20, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
$129 nightly
The price is $145 total per night from Sep 24 to Sep 25
$145 total
Sep 24 - Sep 25
Total with taxes and fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (532 reviews)
"We spent a weekend at Douglas House. Very convenient. The staff was amazing and very knowledgeable. We will stay there again"
Reviewed on Sep 21, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
$116 nightly
The price is $130 total per night from Sep 23 to Sep 24
$130 total
Sep 23 - Sep 24
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very Good! (1,445 reviews)
"Everything was great . The bed left a lot to be desired. I'm glad we only stayed 2 days. The bed was like it was worn out. I was was hard. The mattress had a big hole worn into the middle. I don't know about any of the other beds. My bed I why the only got 2 stars. I would have given then5 stars, ..."
Reviewed on Sep 22, 2026
Southernmost House - Adult Exclusive
1400 Duval Street Key West FL
$261 nightly
The price is $294 total per night from Sep 24 to Sep 25
$294 total
Sep 24 - Sep 25
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, parking (surcharge), and daily housekeeping. Our guests praise the helpful staff and the property ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval
Learn more about Uptown - Upper Duval
Old Town Key West
If you're spending some time in Old Town Key West, Duval Street and Florida Keys Beaches are top sights worth seeing.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Florida Keys Beaches.
New Town
Though New Town might not have many top sights, you can venture to the surrounding area to see attractions like Smathers Beach and Key West Tropical Forest and Botanical Garden.
Uptown - Upper Duval, FL
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