Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Miami to Key West Day Trip with Activity Options
$39
per adult
82% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
$55
per adult
88% of travellers recommend
Sunset Dinner Cruise in Key West with Live Music & Unlimited Open Bar!
$76
per adult
88% of travellers recommend
Shipwreck Treasure Museum Tickets
$19
per adult
78% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$330 nightly
The price is $372 total per night from May 19 to May 20
$372 total
May 19 - May 20
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,232 reviews)
.
Reviewed on Apr 24, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
$239 nightly
The price is $269 total per night from May 26 to May 27
$269 total
May 26 - May 27
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very Good! (1,330 reviews)
The breakfast was less than expected, nothing cooked fresh, mixed fruit in a bowl that all tasted like cantelope and pre pkgd boiled eggs. Coffee machine worked well. Hot tub and heated pool was awesome. Stairs leading up to our room were straight up and very narrow. Coming down was treacherous, ...
Reviewed on Apr 24, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
$330 nightly
The price is $371 total per night from May 4 to May 5
$371 total
May 4 - May 5
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,003 reviews)
Wonderful beach view. Comfortable, clean room, excellent restaurants and service.
Reviewed on Apr 24, 2026
Southwinds Motel
1321 Simonton Street Key West FL
$223 nightly
The price is $251 total per night from Apr 27 to Apr 28
$251 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,316 reviews)
That is our second time staying there and we absolutely enjoy the place. We enjoy the location. It’s quick to walk to. We enjoy the beach access. Everybody is so familiar there. We will be staying there again soon.
Reviewed on Apr 24, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
$217 nightly
The price is $244 total per night from May 6 to May 7
$244 total
May 6 - May 7
Total with taxes and fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (363 reviews)
Wonderful location and very clean with amazing staff.
Reviewed on Apr 24, 2026
Santa Maria Suites
1401 Simonton St Key West FL
$449 nightly
The price is $505 total per night from May 25 to May 26
$505 total
May 25 - May 26
Total with taxes and fees
Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,000 reviews)
.
Reviewed on Apr 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(229 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Bahama Village
5/5(39 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
4.5/5(4,090 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Florida Keys Beaches and Clarence S. Higgs Memorial Beach Park.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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