Title: Visit Uptown - Upper Duval: 2026 Uptown - Upper Duval, Key West Travel Guide | Expedia.com

[Hotels in Uptown - Upper Duval](https://expedia.com/Uptown-Upper-Duval-Key-West-Hotels.0-n553248635976473524-0.Travel-Guide-Filter-Hotels)[Flights to Key West](https://expedia.com/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.com/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Car Rentals in Uptown - Upper Duval](https://expedia.com/Car-Rentals-In-Uptown-Upper-Duval.d553248635976473524.Car-Rental-Guide)[Uptown - Upper Duval Vacations](https://expedia.com/Uptown-Upper-Duval.d553248635976473524.Destination-Travel-Guides)

# Uptown - Upper Duval, FL

## Key West

![Sunset on Carnival Cruise in Key West.](https://images.trvl-media.com/place/1187/48023594-76b8-4930-a4a9-06a0f12911a4.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![SOUTHERNMOST POINT OF CONTINENTAL ASIA. The close the bridge at sunset. Not sure why it says location is key west, it’s definitely Singapore.](https://images.trvl-media.com/place/1187/bf123656-e1f1-4311-8c95-2b851a4b8721.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Hopped off the Old Town Trolley at the Southernmost Point Buoy for some photos. It's a great way to see all of Key West with unlimited hop-on hop-off privileges. 

http://www.trolleytours.com/key-west/ ](https://images.trvl-media.com/place/1187/ca919e5f-361f-4129-b171-77d34c9b6791.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Get here early. Crazy aggressive people in line to take their picture    

#lifeatexpedia ](https://images.trvl-media.com/place/1187/5d488261-cf7f-43ce-a448-690eeb186cd2.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Beautiful hotel on the beach! ](https://images.trvl-media.com/place/1187/c8f3d3ca-f3d1-4ec7-8539-65db27bcc943.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

## Visit Uptown - Upper Duval

Things to do

Hotels

Where to stay

---

### Popular places to visit

![Southernmost Point featuring signage as well as a large group of people](https://images.trvl-media.com/place/501380/97e2b26c-38ce-483b-b59e-7a017404ab35.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Southernmost Point

Snap a memorable photograph from the edge of North America at this monumental landmark.

[](https://expedia.com/Southernmost-Point-Old-Town-Key-West.d501380.Vacation-Attraction)

![South Beach featuring a sandy beach and general coastal views as well as a small group of people](https://images.trvl-media.com/place/6246827/42d13a3e-a933-4e9f-b857-cde9f4314a24.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### South Beach

Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.

[](https://expedia.com/South-Beach-Old-Town-Key-West.d6246827.Vacation-Attraction)

![Key West Butterfly and Nature Conservatory showing animals, zoo animals and food](https://images.trvl-media.com/place/6068597/40321a43-d7c0-4ff6-bffa-8178a19d9be2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Key West Butterfly and Nature Conservatory

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

[](https://expedia.com/Key-West-Butterfly-And-Nature-Conservatory-Old-Town-Key-West.d6068597.Vacation-Attraction)

### Things to do

![Combo image of activity in Key West](https://mediaim.expedia.com/localexpert/191571/36bcc364-ce77-4331-a7d9-4330818bfbfa.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Key West Rum & Reggae: Snorkel & Sunset Sail Combo

$55

per adult

**88%** of travellers recommend

[](https://expedia.com/things-to-do/key-west-rum-reggae-snorkel-sunset-sail-combo.a191571.activity-details)

![Key West: Shark and Wildlife Viewing Catamaran Tour](https://mediaim.expedia.com/localexpert/49301862/1f86e64a-bd95-4e62-b598-309a7a3d7dda.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Key West: Shark and Wildlife Viewing Catamaran Tour

$99

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/key-west-shark-and-wildlife-viewing-catamaran-tour.a49301862.activity-details)

![GLASS BOTTOM BOAT](https://mediaim.expedia.com/localexpert/1344154/fc89f93c-7834-4de4-bc12-2437ae6c1c87.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Miami to Key West Day Trip with Activity Options

$39

per adult

**82%** of travellers recommend

[](https://expedia.com/things-to-do/miami-to-key-west-day-trip-with-activity-options.a1344154.activity-details)

![Entertainer in character at the Shipwreck Treasure Museum in Key West](https://mediaim.expedia.com/localexpert/191533/0194ef1a-54dc-4244-9dae-801c2ad37537.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Shipwreck Treasure Museum Tickets

$19

per adult

**78%** of travellers recommend

[](https://expedia.com/things-to-do/shipwreck-treasure-museum-tickets.a191533.activity-details)

![Sunset Dinner Cruise with Unlimited Open Bar](https://mediaim.expedia.com/localexpert/588408/c9ff1839-c5aa-4d93-9d8e-17eee3f62e60.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Sunset Dinner Cruise in Key West with Live Music & Unlimited Open Bar!

$90

per adult

**88%** of travellers recommend

[](https://expedia.com/things-to-do/sunset-dinner-cruise-in-key-west-with-live-music-unlimited-open-bar.a588408.activity-details)

![Passengers enjoying the shade on the Conch Tour Train in Key West](https://mediaim.expedia.com/localexpert/191535/9b448a2f-ece5-45c7-be77-f9172888dc8f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Key West Conch Tour Train

$45

per adult

**88%** of travellers recommend

[](https://expedia.com/things-to-do/key-west-conch-tour-train.a191535.activity-details)

[See all activities in Key West](https://expedia.com/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)

---

## Uptown - Upper Duval Hotel Deals

![The Reach Key West, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/bc3021c3_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

The Reach Key West, Curio Collection by Hilton

1435 Simonton Street Key West FL

$571 total

per night

Mar 22 - Mar 23

Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...

8.6/10 Excellent! (1,001 reviews)

Resort Room was fine. Balcony small with other balcony to left and right akward

Reviewed on Mar 10, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=457821&PinnedHotelID=457821&HadPinnedHotel=true&regionId=553248635976473524)

![Southwinds Motel](https://images.trvl-media.com/lodging/9000000/8990000/8984500/8984451/45887e0a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Southwinds Motel

1321 Simonton Street Key West FL

$358 total

per night

Apr 5 - Apr 6

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.8/10 Excellent! (1,301 reviews)

Housekeeping was terrible. We came back to our room and saw that housekeeping was in there so we went and sat outside of the lobby so they could do their job. When we went back to our room we found the trash cans still full, the bedding hadn't been changed and the floor wasn't swept. They only come ...

Reviewed on Mar 12, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=8984451&PinnedHotelID=8984451&HadPinnedHotel=true&regionId=553248635976473524)

![The Southernmost Inn - Adults Only](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/a8250942_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

The Southernmost Inn - Adults Only

525 United Street Key West FL

$479 total

per night

Mar 17 - Mar 18

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.2/10 Very Good! (1,277 reviews)

The pool is well kept. The staff was very friendly and competent.

Reviewed on Mar 11, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&selected=4280752&PinnedHotelID=4280752&HadPinnedHotel=true&regionId=553248635976473524)

![Douglas House - Adults Only](https://images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/ba6b4821_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Douglas House - Adults Only

419 Amelia St Key West FL

$333 total

per night

Mar 22 - Mar 23

Stay at this guesthouse in Key West. Enjoy free WiFi, parking (surcharge), and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...

9.6/10 Exceptional! (315 reviews)

Great place to stay. Close to everything. Staff was really nice and the accomdations were wonderful.

Reviewed on Mar 12, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=110488130&PinnedHotelID=110488130&HadPinnedHotel=true&regionId=553248635976473524)

![Orchid Key Inn - Adults Only](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/adc3a7f1_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Orchid Key Inn - Adults Only

1004 Duval St Key West FL

$554 total

per night

Mar 16 - Mar 17

Stay at this hotel in Key West. Enjoy free breakfast, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...

9.8/10 Exceptional! (1,000 reviews)

Great location. All the staff were wonderful.

Reviewed on Mar 12, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=809032&PinnedHotelID=809032&HadPinnedHotel=true&regionId=553248635976473524)

![Santa Maria Suites](https://images.trvl-media.com/lodging/1000000/920000/911000/910922/069776b3_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Santa Maria Suites

1401 Simonton St Key West FL

$766 total

per night

Apr 13 - Apr 14

Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...

9.6/10 Exceptional! (1,002 reviews)

The resort had a very comfortable heated pool with nice grounds, chairs and tables. A staff member was always present offering free water and icee type drinks. Happy hour from 4 to 530 was incredibly generous and good. Rooms were very spacious, clean and up to date. Our stay was enjoyable and we ...

Reviewed on Mar 3, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F13%2F2026&endDate=4%2F14%2F2026&selected=910922&PinnedHotelID=910922&HadPinnedHotel=true&regionId=553248635976473524)

[See all 2,764 properties in Uptown - Upper Duval](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026&regionId=553248635976473524)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=DX-NH_SPRING_PROMO_553248635976473524)

## Check Uptown - Upper Duval hotel availability

[Tonight

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248635976473524&startDate=2026-03-13&endDate=2026-03-14)[Mar 13 - Mar 14](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248635976473524&startDate=2026-03-13&endDate=2026-03-14)

[Tomorrow night

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248635976473524&startDate=2026-03-14&endDate=2026-03-15)[Mar 14 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248635976473524&startDate=2026-03-14&endDate=2026-03-15)

[This weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248635976473524&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248635976473524&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)

---

### Other neighborhoods around Uptown - Upper Duval

![Key West Historic District](https://images.trvl-media.com/place/553248635976481920/c3895c9f-e471-4c93-ac2e-85c99f8f8fec.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Old Town Key West

4.5/5(226 area reviews)

 Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area. 

[](https://expedia.com/Key-West-Old-Town-Key-West.dx553248635976481920)

![Harry S. Truman Little White House which includes a house and cycling](https://images.trvl-media.com/place/6068605/e209543d-9f52-46a8-b0de-136d3f268be5.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Bahama Village

5/5(38 area reviews)

 Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum. 

[](https://expedia.com/Key-West-Bahama-Village.dx553248621533115696)

![Duval Street](https://images.trvl-media.com/place/6068616/ac9e1424-8949-4483-8a12-9063d1511aa2.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown Key West

 If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing. 

[](https://expedia.com/Key-West-Downtown-Key-West.dx553248635976470405)

![Audubon House and Tropical Gardens featuring a house](https://images.trvl-media.com/place/6068599/e22dc889-0174-435e-9d9b-302d362fd045.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Key West Historic District

4.5/5(4,033 area reviews)

 Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district. 

[](https://expedia.com/Key-West-Key-West-Historic-District.dx6281809)

![Not a bad beach, just not very big.](https://images.trvl-media.com/place/1187/d0c11bd8-7e39-4ed6-b09c-d3007de4fe5e.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Casa Marina

 While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches. 

[](https://expedia.com/Key-West-Casa-Marina.dx864981993084186624)

![St. Paul's Episcopal Church, Key West ](https://images.trvl-media.com/place/553248635976482119/ebe24c59-9ab8-4963-a531-5638939859c3.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### White Street Gallery District

 When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area. 

[](https://expedia.com/Key-West-White-Street-Gallery-District.dx553248635976482119)

[See our Where To Stay guide](https://expedia.com/Key-West.dx1187.Where-To-Stay?rfrr=TG.LP.Dest.Neigh.Neighborhoods)

---

---

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# Uptown - Upper Duval, FL

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- [Key West Hotels ](https://www.expedia.com/Key-West-Hotels.d1187.Travel-Guide-Hotels)
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- [Hotels near Tennessee Williams Key West Exhibit ](https://www.expedia.com/Tennessee-Williams-Key-West-Exhibit-Hotels.0-l553248621561885356-0.Travel-Guide-Filter-Hotels)
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- [Golf Hotels in Bahama Village ](https://www.expedia.com/Bahama-Village-Key-West-Hotels-Golf-Hotel.0-n553248621533115696-0-tGolfHotel.Travel-Guide-Filter-Hotels)
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- [Ernest Hemingway Home and Museum ](https://www.expedia.com/Ernest-Hemingway-Home-And-Museum-Old-Town-Key-West.d501376.Vacation-Attraction)
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- [Key West Butterfly and Nature Conservatory ](https://www.expedia.com/Key-West-Butterfly-And-Nature-Conservatory-Old-Town-Key-West.d6068597.Vacation-Attraction)
- [Tennessee Williams Key West Exhibit ](https://www.expedia.com/Tennessee-Williams-Key-West-Exhibit-Old-Town-Key-West.d553248621561885356.Vacation-Attraction)
- [Southernmost Point ](https://www.expedia.com/Southernmost-Point-Old-Town-Key-West.d501380.Vacation-Attraction)
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- [Visit Historic Seaport ](https://www.expedia.com/Key-West-Historic-Seaport.dx553248635976383502)
- [Saint Mary Star of the Sea ](https://www.expedia.com/Saint-Mary-Star-Of-The-Sea-Old-Town-Key-West.d553248621532652618.Vacation-Attraction)
- [Romantic Vacation Packages Key West ](https://www.expedia.com/lp/theme-vacations/romantic-vacations/1187/Key-West)
- [Simonton Beach ](https://www.expedia.com/Simonton-Beach-Old-Town-Key-West.d553248621532652611.Vacation-Attraction)
- [Bahama Village Vacations ](https://www.expedia.com/Bahama-Village.d553248621533115696.Destination-Travel-Guides)
- [Key West Cemetery ](https://www.expedia.com/Key-West-Cemetery-Old-Town-Key-West.d6068615.Vacation-Attraction)

- [Car rentals near Key West ](https://www.expedia.com/Car-Rentals-In-Key-West.d1187.Car-Rental-Guide)
- [Car rentals near Key West Butterfly and Nature Conservatory ](https://www.expedia.com/Car-Rentals-In-Key-West-Butterfly-And-Nature-Conservatory.d6068597.Car-Rental-Guide)
- [Car rentals near Southernmost Point ](https://www.expedia.com/Car-Rentals-In-Southernmost-Point.d501380.Car-Rental-Guide)
- [Car rentals near South Beach ](https://www.expedia.com/Car-Rentals-In-South-Beach.d6246827.Car-Rental-Guide)
- [Car rentals near Duval Street ](https://www.expedia.com/Car-Rentals-In-Duval-Street.d6068616.Car-Rental-Guide)
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- [Hertz Rental Cars in Key West ](https://www.expedia.com/Hertz-Car-Rentals-In-Key-West.d1187-c40.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in Key West ](https://www.expedia.com/Budget-Car-Rentals-In-Key-West.d1187-c39.Car-Rental-Guide-Suppliers)
- [Enterprise Rental Cars in Key West ](https://www.expedia.com/Enterprise-Car-Rentals-In-Key-West.d1187-c15.Car-Rental-Guide-Suppliers)
- [Mini Car Rentals in Key West ](https://www.expedia.com/Mini-Car-Rentals-In-Key-West.d1187-tMini.Car-Rental-Guide-Class)

- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)

- [Things to do in Key West ](https://www.expedia.com/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)

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