Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Stay near popular Uptown - Upper Duval attractions
Things to do
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Champagne and Sunsets: A Key West Catamaran Adventure
$59
per adult
94% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
$61
per adult
88% of travellers recommend
Shipwreck Treasure Museum Tickets
$19
per adult
80% of travellers recommend
Key West Dolphin Watch & Snorkel Combo With Unlimited Beer & Wine
$55
per adult
92% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$247 nightly
The price is $278 total per night from Oct 11 to Oct 12
$278 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,617 reviews)
"The resort itself was nice and most of the staff was super nice! But we paid way too much money for us not to be aware that the big pool was closed for the week and on top of it they ran a power washer for 3 days which sounded like it was inside of or room! It ran from 9-5 only turning off for about ..."
Reviewed on Oct 4, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
$133 nightly
The price is $149 total per night from Oct 7 to Oct 8
$149 total
Oct 7 - Oct 8
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very Good! (1,446 reviews)
"This place was great quiet and close to everything"
Reviewed on Oct 4, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
$215 nightly
The price is $242 total per night from Oct 28 to Oct 29
$242 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,039 reviews)
"We are very thankful to The Reach Hotel for allowing us to check in early on the day of our arrival. We arrived during a heavy rainstorm, at least two hours before the regular check-in time. Despite arriving early, we were graciously given a room and were able to access the restaurants on the property ..."
Reviewed on Oct 4, 2026
Southwinds Motel
1321 Simonton Street Key West FL
$169 nightly
The price is $190 total per night from Oct 6 to Oct 7
$190 total
Oct 6 - Oct 7
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,384 reviews)
"Great location. Third stay here. Will return again Rooms are small but clean fresh coffee every morning."
Reviewed on Oct 3, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
$129 nightly
The price is $145 total per night from Oct 6 to Oct 7
$145 total
Oct 6 - Oct 7
Total with taxes and fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.8/10 Exceptional! (548 reviews)
"Booked this place for my family in early October. Douglas House is in a great location. Close enough to walk to restaurants, shops, and attractions, but away from most of the bar noise. Our rooms were spacious and clean. Balcony was nice for just hanging out. Pool looked nice but we didn't get a ..."
Reviewed on Oct 5, 2026
H2O Suites - Adults Only
1212 Simonton Street Key West FL
$357 nightly
The price is $402 total per night from Oct 13 to Oct 14
$402 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, a rooftop terrace, and a fitness center. Our guests praise the pool and the helpful ...
9.8/10 Exceptional! (663 reviews)
"Great place nice people I love it thank you"
Reviewed on Oct 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval
Learn more about Uptown - Upper Duval
Old Town Key West
If you're spending some time in Old Town Key West, Duval Street and Florida Keys Beaches are top sights worth seeing.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Florida Keys Beaches.
New Town
Though New Town might not have many top sights, you can venture to the surrounding area to see attractions like Smathers Beach and Fort East Martello Museum and Gallery.
Uptown - Upper Duval, FL
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