Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Stay near popular Uptown - Upper Duval attractions
Things to do
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
$79
per adult
94% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
$69
per adult
88% of travellers recommend
Shipwreck Treasure Museum Tickets
$19
per adult
80% of travellers recommend
Afternoon Reef Snorkel & Catamaran Sail w/ Open Bar in Key West
$68
per adult
90% of travellers recommend
Miami to Key West Day Trip with Activity Options
$39
per adult
84% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
Fully refundable
$203 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,516 reviews)
"Beware when visiting this resort. I recently stayed two nights and did not have a good experience. Although it is of no fault of the resort, the sargassum is horrendous. Beach is unavailable and the smell is very strong especially if you have an ocean view. Despite this, the resort fees remain at ..."
Reviewed on Aug 13, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
$216 nightly
The price is $243 total per night from Sep 3 to Sep 4
$243 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Southwinds Motel
1321 Simonton Street Key West FL
$155 nightly
The price is $175 total per night from Aug 30 to Aug 31
$175 total
Aug 30 - Aug 31
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
Douglas House - Adults Only
419 Amelia St Key West FL
$109 nightly
The price is $123 total per night from Aug 25 to Aug 26
$123 total
Aug 25 - Aug 26
Total with taxes and fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (488 reviews)
"This place was everything!!! Location was great, the room was big and spacious, we were able to bring our little dog with us and having the pool was delightful. The company we had while staying was top notch. We are definitely returning! Thanks Douglas house!"
Reviewed on Aug 12, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
$143 nightly
The price is $161 total per night from Aug 17 to Aug 18
$161 total
Aug 17 - Aug 18
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
Santa Maria Suites
1401 Simonton St Key West FL
$339 nightly
The price is $381 total per night from Aug 23 to Aug 24
$381 total
Aug 23 - Aug 24
Total with taxes and fees
Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,009 reviews)
"The hotel was beautiful, luxurious, well decorated, and clean. The housekeeping did a great job taking care of us & our suite. The desk staff at check in was exceptionally friendly, helpful, & professional. Great location near the beach and walking distance to shopping, restaurants, sites. The pool ..."
Reviewed on Aug 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval
Learn more about Uptown - Upper Duval
Old Town Key West
If you're spending some time in Old Town Key West, Duval Street and Florida Keys Beaches are top sights worth seeing.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Florida Keys Beaches.
New Town
Though New Town might not have many top sights, you can venture to the surrounding area to see attractions like Smathers Beach and Key West Tropical Forest and Botanical Garden.
Uptown - Upper Duval, FL
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- Visit Geiger Key
- Visit Boca Chica Key
- Visit Historic Seaport
- Visit Sunset Key
- Visit Old Town Key West
- Visit Summerland Key
- All inclusive Vacation Packages Key West
- Visit Big Pine Key
- Ernest Hemingway Home and Museum
- Visit Lower Keys
- Visit Cudjoe Key
- Smathers Beach
- Visit Little Torch Key
- Visit Truman Annex
- Visit Ramrod Key
- Visit Lower Florida Keys
- Visit Sugarloaf Shores
- Key West Vacations
- Key West Historic District Vacations
- Visit Big Torch Key
- Visit Raccoon Key
- Visit Bahama Village
- Clarence S. Higgs Memorial Beach Park
- Visit Cow Key
- Visit Eden Pines
- Visit Monroe County
- Visit Downtown Key West
- Visit Melody Key
- Visit Key West
- Visit Key West Historic District
- Visit Dredgers Key
- Visit New Town
- Visit Fleming Key
- Visit Stock Island
- Visit Sugarloaf Key
- Visit Rockland Key
