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Recommended hotels in Cairo

1. Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.4 out of 10, (297 reviews)
$70 nightly
The price is $78
Dec 4 - Dec 5
Total with taxes and fees

2. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (685 reviews)
$59 nightly
The price is $66
Dec 1 - Dec 2
Total with taxes and fees

3. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (107 reviews)
$66 nightly
The price is $74
Nov 12 - Nov 13
Total with taxes and fees

4. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (443 reviews)
$66 nightly
The price is $74
Nov 13 - Nov 14
Total with taxes and fees

5. La Center Motel
La Center MotelLa Center
8.0 out of 10, Very good, (25 reviews)
$57 nightly
The price is $61
Nov 14 - Nov 15
Total with taxes and fees

6. Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
$271 nightly
The price is $290
Nov 23 - Nov 24
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Cairo
At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.




















