Title: Enterprise Car Rentals in Santiago Island - Expedia.com ![](https://images.trvl-media.com/place/6336382/a64f32d4-e200-431c-89af-7a17c4de4f0e.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Enterprise Car Rentals in Santiago Island Photo by Sarah Mack - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Find Cheap Enterprise Rental Deals in Santiago Island \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car rentals in Santiago Island [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santiago%20Island,%20Gal%C3%A1pagos,%20Ecuador&dpln=6336381&date1=3/17/2026&date2=3/19/2026&crfrr=defaultFlex&SearchType=Place&selVen=[%2215%22]) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6336381) At Expedia, we are proud to work with Enterprise due to their history of superior customer service as well their large fleet of premier vehicles. Start browsing through the great selection of rental cars by entering your search preferences into our online booking wizard and sorting through everything from spacious SUVs to compact luxury cars. Meaning, whether you need an economy car for a quick business trip or a roomy vehicle to fit the entire family on a long road trip, we’ve got you covered. And, what’s more, we always offer Enterprise Santiago Island cars at the lowest possible prices. Our prices on Enterprise rentals in Santiago Island can’t be beat. Get started and peruse our myriad of cheap deals and discounts on rental cars for your time in Santiago Island today. ## Enterprise Car Rental Information | Car Supplier: | Enterprise | | ------------------------------------------------- | ------------------------------------------------------------------------------------------------------- | | Price: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports: | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Frequently asked questions ### What type of car can I rent in Santiago Island with Enterprise? ### How can I get a cheap Enterprise rental car in Santiago Island with Expedia? ### How much does it cost to rent a car with Enterprise in Santiago Island? ### Why should I rent an Enterprise vehicle through Expedia? ### What happens if I need to cancel my Enterprise rental car reservation? ## Explore a world of travel with Expedia - 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