Prague City Center Vacations from $1,287

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Your Prague City Center Vacation

Packed with charm and character, Prague City Center offers everything from culture to history. Discover the wonders of this neighborhood your way with a tailor-made Prague City Center vacation package. Begin your trip to Prague City Center with a visit to nearby attractions such as Charles Bridge, Old Town Square and Prague Castle. Expedia will help put your plans into action. Book your perfect Prague City Center vacation today.

The Latest Prague City Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Louren Apartments

Louren Apartments

Holesovice
$1,287
per person
Dec 17 - Dec 21
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.6/10 Exceptional! (121 reviews)
Nice place & spacious

Reviewed on Sep 24, 2026

BoHo Prague Hotel, Small Luxury Hotels

BoHo Prague Hotel, Small Luxury Hotels

Prague City Center
Save 100% on your flight
$3,244
per person
Dec 20 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.8/10 Exceptional! (1,001 reviews)
Pytloun Boutique Hotel Prague

Pytloun Boutique Hotel Prague

Prague City Center
$1,686
per person
Dec 17 - Dec 21
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9/10 Wonderful! (685 reviews)
VERY GOOD STAY GOOD BREAKFAST

Reviewed on Sep 8, 2026

MeetMe23 - Hotel

MeetMe23 - Hotel

Prague City Center
$1,518
per person
Nov 28 - Dec 5
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Prague (PRG)
9/10 Wonderful! (588 reviews)
Alchymist Grand Hotel & Spa

Alchymist Grand Hotel & Spa

Prague City Center
$4,168
per person
Dec 20 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.6/10 Exceptional! (464 reviews)

Where to stay in Prague City Center

Find the best Prague City Center areas and neighborhoods for the activities you enjoy most. Learn more about Prague City Center
A historic square with ornate buildings and a prominent church tower.

Stare Mesto

The geographical and historical heart of Prague, this UNESCO-listed district features a tangle of cobblestone streets lined by Baroque churches, palaces and houses.

Find hotels in Stare Mesto
A tram on a city street with historic buildings and a church tower in the background.

Nové Město

1 out of top 10 points of interest in this area

As the largest town in Prague's historic center, New Town boasts landmarks like Wenceslas Square, Dvořák Museum, and Dancing House. Explore its bustling commerce, vibrant tourism, and rich history.

Find hotels in Nové Město
A bustling Christmas market with a large decorated Christmas tree and traditional buildings in the background.

Prague 1

Known for its popular shops and acclaimed art galleries, there's plenty to explore in Prague 1. Check out top attractions like Old Town Square and Royal Route, and jump on the metro at Staromestska Station or Staroměstská Stop to see more of the city.

Find hotels in Prague 1
A cityscape with red-roofed buildings, a prominent church with a green dome, and lush green trees in the foreground.

Mala Strana

This handsome, historical neighborhood, filled with charming cobbled streets, cute courtyards, interesting museums and parks, is perfect for aimless wandering.

Find hotels in Mala Strana
A historic cemetery with ornate tombstones, a church with twin spires, and cobblestone pathways.

Prague 2

Discover the medieval fortress ruins at Vyšehrad, stroll through Riegrovy sady in Vinohrady, or explore Charles Square's Gothic town hall. Easily navigate via I.P. Pavlova station and tramlines.

Find hotels in Prague 2

Prague City Center Hotel Deals

Grandior Hotel Prague

Grandior Hotel Prague

Na Porici 42 Prague
Fully refundableReserve now, pay when you stay
$86 nightly
$100 total
Nov 1 - Nov 2
Total with taxes and fees
9.2/10 Wonderful! (1,267 reviews)
"Cleaning of room was so so Staff very nice Good breakfast Good location"

Reviewed on Oct 5, 2026

Grandior Hotel Prague
Grandium Hotel Prague

Grandium Hotel Prague

Politickych veznu 913/12 Prague
Fully refundableReserve now, pay when you stay
$90 nightly
$105 total
Nov 1 - Nov 2
Total with taxes and fees
9.2/10 Wonderful! (1,043 reviews)
"Room was clean and spacious, breakfast (included) was good with many choices. There was also a nice little bar with a good choice of cocktails."

Reviewed on Oct 5, 2026

Grandium Hotel Prague
ibis Praha Old Town

ibis Praha Old Town

Na Porici 5 Prague
Fully refundableReserve now, pay when you stay
$72 nightly
$85 total
Nov 1 - Nov 2
Total with taxes and fees
8.6/10 Excellent! (1,003 reviews)
"Easy to get to and good folks working the desk!"

Reviewed on Oct 6, 2026

ibis Praha Old Town
See all 1,158 properties in Prague City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Prague City Center attractions

A historic square with a prominent clock tower, traditional European architecture, and a clear blue sky.

Old Town Square

9.6/10 (16,970 reviews)
This public space is as important to the people of Prague today as it was a thousand years ago.
See properties
A busy urban street lined with historic buildings and a statue.

Wenceslas Square

9.0/10 (13,313 reviews)
Prague’s busiest boulevard is great for both shopping and nightlife and has a history as a gathering point for local uprisings and celebrations.
See properties
A stone bridge over a river with a boat, surrounded by greenery and historic buildings in the background.

Prague Castle

9.4/10 (14,742 reviews)
Witness the changing of the guard ceremony at this medieval fortified complex that is now the seat of the President of the Czech Republic and also houses the huge St. Vitus Cathedral.
See properties
A historic cityscape with a prominent bridge, a river, and various colorful buildings including a church with a green dome and a tower with a clock.

Charles Bridge

9.4/10 (15,974 reviews)
This iconic structure with sculptures spans the Vltava River and connects the historic Lesser Town on the west bank with the Old Town on the east bank.
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A detailed astronomical clock with Roman numerals and zodiac signs.

Prague Astronomical Clock

9.2/10 (15,676 reviews)
The hourly show put on by this early 15th-century masterpiece on the Old Town Hall is a must-see event that draws the crowds.
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A cobblestone street with a red building labeled "200 Shops" and a yellow church.

Palladium Shopping Centre

8.6/10 (3,758 reviews)
You can find the perfect gifts to bring home at Palladium Shopping Centre during your visit to Prague. Experience the acclaimed art scene and fascinating museums in this culturally rich area.
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A historic square with a prominent cathedral featuring intricate Gothic architecture and a clock tower.

St. Vitus Cathedral

9.2/10 (6,687 reviews)
Within the grounds of the Prague Castle lies this highly revered church, home of the Czech crown jewels and seat of the archbishop of Prague.
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Republic Square

8.4/10 (425 reviews)
You can learn about the history of Prague with a stop at Republic Square. Experience the acclaimed art scene and fascinating museums in this culturally rich area.
See properties

Things to do

Prague: 50-Minute Sightseeing Evening Cruise

Prague: 50-Minute Sightseeing Evening Cruise

$21
per adult
82% of travellers recommend
Prague: 50-Minute Sightseeing Evening Cruise
Prague: Official Entry Ticket to Prague Castle

Prague: Official Entry Ticket to Prague Castle

$21
per adult
74% of travellers recommend
Prague: Official Entry Ticket to Prague Castle
Prague: Old Town, Medieval Underground & Dungeon Tour

Prague: Oldtown, Medieval Underground & Dungeon History Tour

$17
per child
88% of travellers recommend
Prague: Oldtown, Medieval Underground & Dungeon History Tour
See all activities in Prague

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.