Title: Top Independent in Muleshoe, TX - Expedia.com [Muleshoe Travel Guide](https://expedia.com/Muleshoe.dx184002)[Hotels in Muleshoe](https://expedia.com/Muleshoe-Hotels.d184002.Travel-Guide-Hotels)[Vacation Rentals in Muleshoe](https://expedia.com/Muleshoe-Vacation-Rentals.d184002.Travel-Guide-VacationRentals)[Flights to Muleshoe](https://expedia.com/Cheap-Flights-To-Muleshoe.d184002.Travel-Guide-Flights)[Car Rentals in Muleshoe](https://expedia.com/Car-Rentals-In-Muleshoe.d184002.Car-Rental-Guide)[Muleshoe Vacation Packages](https://expedia.com/Muleshoe.d184002.Destination-Travel-Guides) ![Muleshoe National Wildlife Refuge in Texas, USA](https://images.trvl-media.com/place/184002/6090ab52-ece5-456b-8984-726e1e7986cf.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/184002/6090ab52-ece5-456b-8984-726e1e7986cf.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 16 - Mar 17](https://www.expedia.com/Hotel-Search?regionId=184002&startDate=2026-03-16&endDate=2026-03-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 17 - Mar 18](https://www.expedia.com/Hotel-Search?regionId=184002&startDate=2026-03-17&endDate=2026-03-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=184002&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=184002&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMuleshoe-Hotels-Independent.0-0-d184002--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMuleshoe-Hotels-Independent.0-0-d184002--bIndependent.Travel-Guide-Filter-Hotels) ## Top Muleshoe Hotel Reviews ![Holiday Express & Suites Portales by IHG](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439957/4936b3ae_y.jpg) ### Holiday Express & Suites Portales by IHG 8/10 Good "Pretty nice hotel overall. Good breakfast (omelets, potatoes, biscuits and gravy, sausage) and all the other basic things. One issue was the door on the room. We left the room thinking the door closed all the way behind us due to the powerful hinge they have, but when we returned it in fact had not closed fully. So watch that. I also had issues with getting doors open on our room and the pool room. The shower head sprayed water everywhere. The hot tub was warm but not overly hot. " [](https://expedia.com/Clovis-Hotels-Holiday-Express-Suites-Portales.h1439957.Hotel-Information) ![Comfort Suites Clovis North](https://images.trvl-media.com/lodging/1000000/890000/880400/880372/8c44570e_y.jpg) ### Comfort Suites Clovis North 10/10 Excellent "Spacious room" [](https://expedia.com/Clovis-Hotels-Comfort-Suites.h880372.Hotel-Information) ![Home2 Suites by Hilton Clovis](https://images.trvl-media.com/lodging/75000000/74030000/74025100/74025010/2acaf09e_y.jpg) ### Home2 Suites by Hilton Clovis 10/10 Excellent "Food and gym was good" [](https://expedia.com/Clovis-Hotels-Home2-Suites-By-Hilton-Clovis.h74025010.Hotel-Information) ![Sleep Inn Clovis](https://images.trvl-media.com/lodging/1000000/580000/570500/570423/22583e4a_y.jpg) ### Sleep Inn Clovis 10/10 Excellent "Good location " [](https://expedia.com/Clovis-Hotels-Sleep-Inn.h570423.Hotel-Information) ![Super 8 by Wyndham Clovis](https://images.trvl-media.com/lodging/1000000/50000/42200/42170/7d9b3b35_y.jpg) ### Super 8 by Wyndham Clovis 10/10 Excellent "Great friendly staff " [](https://expedia.com/Clovis-Hotels-Super-8-By-Wyndham-Clovis.h42170.Hotel-Information) ![Days Inn & Suites by Wyndham Clovis](https://images.trvl-media.com/lodging/1000000/10000/100/24/59941d4a_y.jpg) ### Days Inn & Suites by Wyndham Clovis 10/10 Excellent "Good secure parking---friendly staff" [](https://expedia.com/Clovis-Hotels-Days-Inn-Suites-By-Wyndham-Clovis.h24.Hotel-Information) ![Comfort Inn Portales](https://images.trvl-media.com/lodging/37000000/36030000/36023800/36023726/cdc367ca_y.jpg) ### Comfort Inn Portales 10/10 Excellent "AC was effective. Had to lower temp setting lower than usual " [](https://expedia.com/Portales-Hotels-Comfort-Inn.h36023726.Hotel-Information) ![Holiday Inn Express Hotel & Suites Clovis by IHG](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2226965/6e3d4a9e_y.jpg) ### Holiday Inn Express Hotel & Suites Clovis by IHG 10/10 Excellent "Great place" [](https://expedia.com/Clovis-Hotels-Holiday-Inn-Express-Hotel-Suites-Clovis.h2226965.Hotel-Information) ![Best Western Cannon A.F.B.](https://images.trvl-media.com/lodging/2000000/1690000/1681600/1681513/67396999_y.jpg) ### Best Western Cannon A.F.B. 10/10 Excellent "Staff was friendly " [](https://expedia.com/Clovis-Hotels-Best-Western-Cannon-AFB.h1681513.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near National Mule Memorial ](https://www.expedia.com/National-Mule-Memorial-Hotels.0-l6225208-0.Travel-Guide-Filter-Hotels) - [Hotels near Muleshoe Golf and Country Club ](https://www.expedia.com/Muleshoe-Golf-And-Country-Club-Hotels.0-l6225206-0.Travel-Guide-Filter-Hotels) - [Hotels near Muleshoe Heritage Center ](https://www.expedia.com/Muleshoe-Heritage-Center-Hotels.0-l6225211-0.Travel-Guide-Filter-Hotels) - [Sudan Hotels ](https://www.expedia.com/Sudan-Hotels.d553248634999266639.Travel-Guide-Hotels) - [Earth Hotels ](https://www.expedia.com/Earth-Hotels.d3000458413.Travel-Guide-Hotels) - [Hotels near Muleshoe National Wildlife Refuge ](https://www.expedia.com/Muleshoe-National-Wildlife-Refuge-Hotels.0-l553248621532645835-0.Travel-Guide-Filter-Hotels) - [Springlake Hotels ](https://www.expedia.com/Springlake-Hotels.d553248634998991047.Travel-Guide-Hotels) - [Friona Hotels ](https://www.expedia.com/Friona-Hotels.d55115.Travel-Guide-Hotels) - [Motels in Friona ](https://www.expedia.com/Friona-Motels.d55115-aaMotels.Travel-Guide-Accommodation) - [3 Star Hotels in Friona ](https://www.expedia.com/3Star-Friona-Hotels.s30-0-d55115.Travel-Guide-Filter-Hotels) - [Hotels near Laguna Park ](https://www.expedia.com/Laguna-Park-Hotels.0-l553248621565118532-0.Travel-Guide-Filter-Hotels) - [Littlefield Hotels ](https://www.expedia.com/Littlefield-Hotels.d184001.Travel-Guide-Hotels) - [Hotels with Free Breakfast in Littlefield ](https://www.expedia.com/Littlefield-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d184001-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Littlefield ](https://www.expedia.com/Littlefield-Hotels-Spa-Hotel.0-0-d184001-tSpaHotel.Travel-Guide-Filter-Hotels) - [Motels in Littlefield ](https://www.expedia.com/Littlefield-Motels.d184001-aaMotels.Travel-Guide-Accommodation) - [Hotels with a Pool in Littlefield ](https://www.expedia.com/Littlefield-Hotels-Hotel-With-Pool.0-0-d184001-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Littlefield ](https://www.expedia.com/Littlefield-Hotels-Hotels-With-Hot-Tubs.0-0-d184001-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Littlefield ](https://www.expedia.com/4Star-Littlefield-Hotels.s40-0-d184001.Travel-Guide-Filter-Hotels) - [Dimmitt Hotels ](https://www.expedia.com/Dimmitt-Hotels.d6348022.Travel-Guide-Hotels) - [Motels in Dimmitt ](https://www.expedia.com/Dimmitt-Motels.d6348022-aaMotels.Travel-Guide-Accommodation) - [Olton Hotels ](https://www.expedia.com/Olton-Hotels.d3000459124.Travel-Guide-Hotels) - [4 Star Hotels in Olton ](https://www.expedia.com/4Star-Olton-Hotels.s40-0-d3000459124.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Olton ](https://www.expedia.com/3Star-Olton-Hotels.s30-0-d3000459124.Travel-Guide-Filter-Hotels) - [Hotels near Spade ](https://www.expedia.com/Spade-Lubbock-Hotels.0-n3000354494-0.Travel-Guide-Filter-Hotels) - [Cochran County Hotels ](https://www.expedia.com/Destinations-In-Cochran-County.d553248635976433589.Hotel-Destinations) - [Morton Hotels ](https://www.expedia.com/Morton-Hotels.d553248634998798861.Travel-Guide-Hotels) - [Hart Hotels ](https://www.expedia.com/Hart-Hotels.d553248634999428802.Travel-Guide-Hotels) - [Nazareth Hotels ](https://www.expedia.com/Nazareth-Hotels.d553248634998743418.Travel-Guide-Hotels) - [Anton Hotels ](https://www.expedia.com/Anton-Hotels.d553248634998991675.Travel-Guide-Hotels) - [Whiteface Hotels ](https://www.expedia.com/Whiteface-Hotels.d553248634998781009.Travel-Guide-Hotels) - [Hotels near Jaycee Park ](https://www.expedia.com/Jaycee-Park-Hotels.0-l553248621565118522-0.Travel-Guide-Filter-Hotels) - [Hotels near John Pitman Municipal Golf Course ](https://www.expedia.com/John-Pitman-Municipal-Golf-Course-Hotels.0-l553248621565118521-0.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-Motel-6.0-0-d8336--bMotel6.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-La-Quinta-Inn-Suites.0-0-d8336--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Extended Stay America Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-Extended-Stay-America.0-0-d8336--bExtendedStayAmerica.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-Hilton-Hotels.0-0-d8336--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Hereford ](https://www.expedia.com/Hereford-Hotels-Marriott-Hotels-Resorts.0-0-d8336--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-Wyndham-Hotels.0-0-d8336--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Hereford Hotels ](https://www.expedia.com/Hereford-Hotels.d8336.Travel-Guide-Hotels) - [Hotels near Deaf Smith County Historical Museum ](https://www.expedia.com/Deaf-Smith-County-Historical-Museum-Hotels.0-l553248621561866750-0.Travel-Guide-Filter-Hotels) - [Motels in Hereford ](https://www.expedia.com/Hereford-Motels.d8336-aaMotels.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-Pet-Friendly-Hotel.0-0-d8336-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Hereford ](https://www.expedia.com/Hereford-Hotels-Hotels-With-Indoor-Pool.0-0-d8336-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Hereford ](https://www.expedia.com/Hereford-Cabins.d8336-aaCabins.Travel-Guide-Accommodation) - [Hotels with Restaurants in Hereford ](https://www.expedia.com/Hereford-Hotels-Hotels-With-Restaurants.0-0-d8336-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Business Hotels in Hereford ](https://www.expedia.com/Hereford-Hotels-Business-Hotel.0-0-d8336-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Outdoor Pool in Hereford ](https://www.expedia.com/Hereford-Hotels-Hotels-With-Outdoor-Pool.0-0-d8336-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels) - [Hotels with a Gym in Hereford ](https://www.expedia.com/Hereford-Hotels-Hotels-With-Fitness-Center.0-0-d8336-tHotelswithFitnessCenter.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Hereford ](https://www.expedia.com/Hereford-Hotels-Hotels-With-Hot-Tubs.0-0-d8336-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Flights from Earth ](https://www.expedia.com/lp/flights/3000458413/flights-from-earth) - [Flights to Earth ](https://www.expedia.com/Cheap-Flights-To-Earth.d3000458413.Travel-Guide-Flights) - [Flights to Friona ](https://www.expedia.com/Cheap-Flights-To-Friona.d55115.Travel-Guide-Flights) - [Flights from Friona ](https://www.expedia.com/lp/flights/55115/flights-from-friona) - [Flights to Littlefield ](https://www.expedia.com/Cheap-Flights-To-Littlefield.d184001.Travel-Guide-Flights) - [Flights from Littlefield ](https://www.expedia.com/lp/flights/184001/flights-from-littlefield) - [Flights to Dimmitt ](https://www.expedia.com/Cheap-Flights-To-Dimmitt.d6348022.Travel-Guide-Flights) - [Flights to Olton ](https://www.expedia.com/Cheap-Flights-To-Olton.d3000459124.Travel-Guide-Flights) - [Flights from Morton ](https://www.expedia.com/lp/flights/553248634998798861/flights-from-morton) - [Flights to Whitharral ](https://www.expedia.com/Cheap-Flights-To-Whitharral.d3000354553.Travel-Guide-Flights) - [Flights from Whiteface ](https://www.expedia.com/lp/flights/553248634998781009/flights-from-whiteface) - [Flights to Hereford ](https://www.expedia.com/Cheap-Flights-To-Hereford.d8336.Travel-Guide-Flights) - [Flights from Hereford ](https://www.expedia.com/lp/flights/8336/flights-from-hereford) - [National Mule Memorial ](https://www.expedia.com/National-Mule-Memorial-Muleshoe.d6225208.Vacation-Attraction) - [Muleshoe Golf and Country Club ](https://www.expedia.com/Muleshoe-Golf-And-Country-Club-Muleshoe.d6225206.Vacation-Attraction) - [Muleshoe Heritage Center ](https://www.expedia.com/Muleshoe-Heritage-Center-Muleshoe.d6225211.Vacation-Attraction) - [Visit Earth ](https://www.expedia.com/Earth.dx3000458413) - [Visit Friona ](https://www.expedia.com/Friona.dx55115) - [Laguna Park ](https://www.expedia.com/Laguna-Park-Lubbock.d553248621565118532.Vacation-Attraction) - [Littlefield Vacations ](https://www.expedia.com/Littlefield.d184001.Destination-Travel-Guides) - [Crescent Park ](https://www.expedia.com/Crescent-Park-Lubbock.d553248621565118531.Vacation-Attraction) - [Visit Dimmitt ](https://www.expedia.com/Dimmitt.dx6348022) - [Visit Olton ](https://www.expedia.com/Olton.dx3000459124) - [Olton Vacations ](https://www.expedia.com/Olton.d3000459124.Destination-Travel-Guides) - [Visit Whitharral ](https://www.expedia.com/Whitharral.dx3000354553) - [Jaycee Park ](https://www.expedia.com/Jaycee-Park-Hereford.d553248621565118522.Vacation-Attraction) - [John Pitman Municipal Golf Course ](https://www.expedia.com/John-Pitman-Municipal-Golf-Course-Hereford.d553248621565118521.Vacation-Attraction) - [Deaf Smith County Historical Museum ](https://www.expedia.com/Deaf-Smith-County-Historical-Museum-Hereford.d553248621561866750.Vacation-Attraction) - [Visit Hereford ](https://www.expedia.com/Hereford.dx8336) - [Hereford Vacations ](https://www.expedia.com/Hereford.d8336.Destination-Travel-Guides) - [Car rentals near Earth ](https://www.expedia.com/Car-Rentals-In-Earth.d3000458413.Car-Rental-Guide) - [Car rentals near Farwell ](https://www.expedia.com/Car-Rentals-In-Farwell.d553248634983104085.Car-Rental-Guide) - [Car rentals near Bovina ](https://www.expedia.com/Car-Rentals-In-Bovina.d553248634998904762.Car-Rental-Guide) - [Car rentals near Amherst ](https://www.expedia.com/Car-Rentals-In-Amherst.d553248634998809039.Car-Rental-Guide) - [Car rentals near Friona ](https://www.expedia.com/Car-Rentals-In-Friona.d55115.Car-Rental-Guide) - [Car rentals near Littlefield ](https://www.expedia.com/Car-Rentals-In-Littlefield.d184001.Car-Rental-Guide) - [Car rentals near Dimmitt ](https://www.expedia.com/Car-Rentals-In-Dimmitt.d6348022.Car-Rental-Guide) - [Car rentals near Olton ](https://www.expedia.com/Car-Rentals-In-Olton.d3000459124.Car-Rental-Guide) - [Car rentals near Spade ](https://www.expedia.com/Car-Rentals-In-Spade.d3000354494.Car-Rental-Guide) - [Car rentals near Hart ](https://www.expedia.com/Car-Rentals-In-Hart.d553248634999428802.Car-Rental-Guide) - [Car rentals near Anton ](https://www.expedia.com/Car-Rentals-In-Anton.d553248634998991675.Car-Rental-Guide) - [Car rentals near Hereford ](https://www.expedia.com/Car-Rentals-In-Hereford.d8336.Car-Rental-Guide) - [Van Car Rentals in Hereford ](https://www.expedia.com/Van-Car-Rentals-In-Hereford.d8336-tVan.Car-Rental-Guide-Class) - [Hertz Rental Cars in Hereford ](https://www.expedia.com/Hertz-Car-Rentals-In-Hereford.d8336-c40.Car-Rental-Guide-Suppliers) - [Earth Vacation Rentals ](https://www.expedia.com/Earth-Vacation-Rentals.d3000458413.Travel-Guide-VacationRentals) - [Friona Vacation Rentals ](https://www.expedia.com/Friona-Vacation-Rentals.d55115.Travel-Guide-VacationRentals) - [Littlefield Vacation Rentals ](https://www.expedia.com/Littlefield-Vacation-Rentals.d184001.Travel-Guide-VacationRentals) - [Dimmitt Vacation Rentals ](https://www.expedia.com/Dimmitt-Vacation-Rentals.d6348022.Travel-Guide-VacationRentals) - [Olton Vacation Rentals ](https://www.expedia.com/Olton-Vacation-Rentals.d3000459124.Travel-Guide-VacationRentals) - [Whitharral Vacation Rentals ](https://www.expedia.com/Whitharral-Vacation-Rentals.d3000354553.Travel-Guide-VacationRentals) - [Hereford Vacation Rentals ](https://www.expedia.com/Hereford-Vacation-Rentals.d8336.Travel-Guide-VacationRentals)