Title: Visit Old Appleton: 2026 Travel Guide for Old Appleton, Missouri | Expedia.com [Hotels in Old Appleton](https://expedia.com/Old-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels)[Vacation Rentals in Old Appleton](https://expedia.com/Old-Appleton-Vacation-Rentals.d553248634983492471.Travel-Guide-VacationRentals)[Car Rentals in Old Appleton](https://expedia.com/Car-Rentals-In-Old-Appleton.d553248634983492471.Car-Rental-Guide)[Old Appleton Vacation Packages](https://expedia.com/Old-Appleton.d553248634983492471.Destination-Travel-Guides) # Old Appleton, MO ## Travel Guide ## Visit Old Appleton - Old Appleton Hotel Deals - Vacation Rentals in Old Appleton ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 3003 SOUTH OLD ORCHARD ROAD Jackson MO $89 nightly $96 total Mar 29 - Mar 30 Total with taxes and fees Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ... 9/10 Wonderful! (731 reviews) Hotel staff were friendly and helpful. Store and restaurants were a short drive away. Reviewed on Mar 17, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=53348099&PinnedHotelID=53348099&HadPinnedHotel=true®ionId=553248634983492471) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Jackson MO 225 Drury Lane Jackson MO Fully refundableReserve now, pay when you stay $80 nightly $85 total Apr 8 - Apr 9 Total with taxes and fees Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ... 9.6/10 Exceptional! (1,006 reviews) Great stay. Clean, good food and staff was exceptional Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F8%2F2026&endDate=4%2F9%2F2026&selected=41077&PinnedHotelID=41077&HadPinnedHotel=true®ionId=553248634983492471) ![Quality Inn Cape Girardeau North](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Quality Inn Cape Girardeau North 2011 North Kingshighway Cape Girardeau MO $67 nightly $75 total Apr 1 - Apr 2 Total with taxes and fees Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ... 7.2/10 Good! (714 reviews) It needs some updates and remodeling. The bathroom was clean, but the shower had very little pressure. The "breakfast" was not really breakfast. However the staff was polite and helpful in giving me a first floor room. The bed was comfortable. It was adequate for my business trip. Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=855988&PinnedHotelID=855988&HadPinnedHotel=true®ionId=553248634983492471) [See all 61 properties in Old Appleton](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F26%2F2026&endDate=3%2F27%2F2026®ionId=553248634983492471) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck! ](https://images.trvl-media.com/lodging/33000000/32070000/32068400/32068377/2fd131ea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck! Alto Pass IL Stay at this cabin in Alto Pass. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Von Jakob Winery & Brewery and Pomona Winery are located ... 9.8/10 Exceptional! (178 reviews) Loved all parts of our stay besides the lady bugs. Lots of lady bugs in the master bed and bath. We simply vacuumed as many as we could up and they seemed to stay away for the most part. Other than that it was a beautiful place and we would definitely book again. Reviewed on Mar 24, 2026 [](https://expedia.com/Alto-Pass-Hotels-Big-Sky-Cabin-Hot-Tub-On-The-Wine-Trail-Fire-Pit-Pool-Table-Large-Deck.h32068377.Hotel-Information) ![Beautiful location in the secluded woods ](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/38c121bf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beautiful location in the secluded woods Pomona IL Stay at this vacation home in Pomona. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Pomona Winery and Von Jakob Winery & Brewery are located ... 10/10 Exceptional! (65 reviews) Host was very helpful and prompt when we ran into issues. Properry was beautiful. You are definitely in the middle of no where out there and right in the middle of the wine trail which is exactly what we were looking for. Reviewed on Mar 15, 2026 [](https://expedia.com/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ![Notting Hill Cottage](https://images.trvl-media.com/lodging/49000000/49000000/48991900/48991852/612a5086_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Notting Hill Cottage Alto Pass IL Stay at this vacation home in Alto Pass. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions Peachbarn Winery and Von Jakob Winery ... 9.6/10 Exceptional! (331 reviews) Accessing the property was very easy. Perfect amount of space for the two of us. Well controlled HVAC, never cold or hot, just right. Deck was very spacious, quiet, sitting on it relaxing was great. Hot tub being sunken into the deck was great as in February could get pretty chilly out, so sitting ... Reviewed on Feb 27, 2026 [](https://expedia.com/Alto-Pass-Hotels-Notting-Hill-Cottage.h48991852.Hotel-Information) [See all properties in Old Appleton](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983492471&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Old Appleton hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=2026-03-25&endDate=2026-03-26)[Mar 25 - Mar 26](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=2026-03-25&endDate=2026-03-26) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=2026-03-26&endDate=2026-03-27)[Mar 26 - Mar 27](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=2026-03-26&endDate=2026-03-27) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983492471&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026) ## Cities near Old Appleton ![Arched train bridge](https://images.trvl-media.com/place/6134448/9dc94c46-c0ab-4d3f-b5fe-2d6ecd4d81c3.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Perryville - Cities near Old Appleton - Places of interest [Perryville](https://expedia.com/Perryville.dx6134448) - [Shawnee National Forest ](https://expedia.com/Shawnee-National-Forest-Illinois.d553248635944113522.Vacation-Attraction) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [National Shrine of Our Lady of the Miraculous Medal ](https://expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Perryville.d553248621561876731.Vacation-Attraction) - [Trail of Tears State Park ](https://expedia.com/Trail-Of-Tears-State-Park-Missouri.d553248621532655784.Vacation-Attraction) - [Hunter Valley Winery ](https://expedia.com/Hunter-Valley-Winery-Cape-Girardeau.d553248621532655783.Vacation-Attraction) - [Pomona Winery ](https://expedia.com/Pomona-Winery-Pomona.d553248621532655793.Vacation-Attraction) - [Cape Girardeau Conservation Nature Center ](https://expedia.com/Cape-Girardeau-Conservation-Nature-Center-Cape-Girardeau.d553248621532655773.Vacation-Attraction) - [Perryville Country Club ](https://expedia.com/Perryville-Country-Club-Perryville.d553248621564822920.Vacation-Attraction) - [The Bluffs Vineyard and Winery ](https://expedia.com/The-Bluffs-Vineyard-And-Winery-Gorham.d553248621532655791.Vacation-Attraction) - [Missouri's National Veterans Memorial ](https://expedia.com/Missouris-National-Veterans-Memorial-Perryville.d620724250067501056.Vacation-Attraction) - [Litz Park ](https://expedia.com/Litz-Park-Jackson.d553248621554122991.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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