Title: Top 10 Hotels in Old Appleton, MO from $73 - Competitive Prices | Expedia.com [Vacation Rentals in Old Appleton](https://expedia.com/Old-Appleton-Vacation-Rentals.d553248634983492471.Travel-Guide-VacationRentals)[Car Rentals in Old Appleton](https://expedia.com/Car-Rentals-In-Old-Appleton.d553248634983492471.Car-Rental-Guide)[Old Appleton Vacation Packages](https://expedia.com/Old-Appleton.d553248634983492471.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Old Appleton Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&amenities=PETS) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&travelerType=family_friendly) Pool [](https://www.expedia.com/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&amenities=POOL) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&lodging=APARTMENT) ## Check prices for these dates Tonight [Mar 24 - Mar 25](https://www.expedia.com/Hotel-Search?regionId=553248634983492471&startDate=2026-03-24&endDate=2026-03-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 25 - Mar 26](https://www.expedia.com/Hotel-Search?regionId=553248634983492471&startDate=2026-03-25&endDate=2026-03-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=553248634983492471&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248634983492471&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Old Appleton hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/b5f01af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1,005 reviews) "The staff is so nice here" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura $80 nightly $85 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (730 reviews) "Very clean and staff was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nastassia $89 nightly $96 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/ef8850d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very Good (967 reviews) "Excellent place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim $65 nightly $75 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/2b5bb07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/ab22ad5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/0c87c756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) Perryville 9.2/10 Wonderful (570 reviews) "Room was great, front desk was professional but friendly. Breakfast was excellent. Spotless — both room and lobby. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $95 nightly $109 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c66d7d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (714 reviews) "It was ok no elevator though " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $67 nightly $75 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (116 reviews) "Hotel was very clean, quiet and has a great location! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustin $95 nightly $108 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/8a502333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/0ac4753f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very Good (754 reviews) "Beds felt amazing. My family and I had a great time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $92 nightly $100 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Room, 1 King Bed | Jetted tub](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/19d8e2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Perryville 6.8/10 (427 reviews) "Parking was easy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Binggang $71 nightly $82 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, 2 Queen Beds, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/affd3e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/00115e7b_edited_b2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (440 reviews) "Everything was excellent and comfortable beds " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wesley $67 nightly $73 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/01a032b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/0d3bba3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/6b56391d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Perryville 6.6/10 (128 reviews) "satisfactory" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $80 nightly $92 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/804f0425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/aa7536c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/2cb1c224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/9e44784b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atrium - A Boutique Hotel [](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information) Perryville $116 nightly $134 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/a7c17063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/e0117cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/c1e6c8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/b3f96c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mediterranean House 1858 [](https://www.expedia.com/Perryville-Hotels-The-Mediterranean-House-1858.h126618348.Hotel-Information) Perryville $535 nightly $615 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-The-Mediterranean-House-1858.h126618348.Hotel-Information) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/2ec33dcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts [](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) Perryville 9.2/10 Wonderful (17 reviews) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $260 nightly $297 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=553248634983492471&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels) ## Top Old Appleton Hotel Reviews ![Quality Inn Cape Girardeau North](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn Cape Girardeau North 6/10 Okay "It needs some updates and remodeling. The bathroom was clean, but the shower had very little pressure. The "breakfast" was not really breakfast. However the staff was polite and helpful in giving me a first floor room. The bed was comfortable. It was adequate for my business trip. " [](https://expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08_y.jpg) ### Super 8 by Wyndham Perryville 10/10 Excellent "Great" [](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Very comfortable room. Enjoyed the light evening meal and breakfast included with the room. The hot tub was nice as well." [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Hot Tub & Creek Views: Secluded Perryville Cabin](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/a61e25be_y.jpg) ### Hot Tub & Creek Views: Secluded Perryville Cabin 8/10 Good "If you are looking for a secluded stay this is it! It is just as listed, rustic, historic, quaint and quiet. It was a great place for my cousins and I to have a get together. The owner was very attentive and came right away when we had a problem with the fireplace and hot tub. If you are looking for a five star resort this is not for you. If you are looking to relax in the country it will not disappoint." [](https://expedia.com/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 10/10 Excellent "The hotel and room were very clean. It was in a quiet area. " [](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Comfort Suites Jackson-Cape Girardeau](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487_y.jpg) ### Comfort Suites Jackson-Cape Girardeau 4/10 Poor "There was no water pressure, luke warm water both nights. The breakfast was subpar & with an hour left with breakfast the workers refused to refill empty items. Several people complained to no avail. Breakfast area was dirty & two people sitting upfront playing on their phones. We made our first & last stay here!!" [](https://expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Hotel staff were friendly and helpful. Store and restaurants were a short drive away." [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858_y.jpg) ### Days Inn by Wyndham Perryville 6/10 Okay "furniture worn off, ok breakfast, but right off freeway so easy access" [](https://expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Beautiful location in the secluded woods ](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/38c121bf_y.jpg) ### Beautiful location in the secluded woods 10/10 Excellent "Host was very helpful and prompt when we ran into issues. Properry was beautiful. You are definitely in the middle of no where out there and right in the middle of the wine trail which is exactly what we were looking for." [](https://expedia.com/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ## More cheap stays in Old Appleton ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Town House Inn 517 E Jackson Blvd Jackson MO $67 nightly $73 total Mar 31 - Apr 1 Total with taxes and fees 7.6/10 Good! (440 reviews) [](https://expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr Perryville MO $65 nightly $75 total Apr 5 - Apr 6 Total with taxes and fees 8.4/10 Very Good! (967 reviews) [](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Quality Inn Cape Girardeau North](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Cape Girardeau North 2011 North Kingshighway Cape Girardeau MO $67 nightly $75 total Mar 31 - Apr 1 Total with taxes and fees 7.2/10 Good! (714 reviews) [](https://expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Perryville 1500 Liberty Street Perryville MO $71 nightly $82 total Mar 26 - Mar 27 Total with taxes and fees 6.8/10 (427 reviews) [](https://expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Comfort Suites Jackson-Cape Girardeau](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Jackson-Cape Girardeau 2904 Old Orchard Rd Jackson MO $92 nightly $100 total Mar 29 - Mar 30 Total with taxes and fees 8.2/10 Very Good! (754 reviews) [](https://expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St Perryville MO $95 nightly $109 total Mar 29 - Mar 30 Total with taxes and fees 9.2/10 Wonderful! (570 reviews) [](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ## Hotels in Old Appleton with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Old-Appleton-Hotels.s40-0-d553248634983492471.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 5 properties [](https://expedia.com/3Star-Old-Appleton-Hotels.s30-0-d553248634983492471.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 11 properties [](https://expedia.com/2Star-Old-Appleton-Hotels.s20-0-d553248634983492471.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Old Appleton? > This area is centered around the Old Appleton Bridge and the Apple Creek, offering a picturesque setting with historical buildings and a relaxed pace. It's a small, walkable community where the main attractions are the natural beauty and the preserved heritage. > > > Couples looking for a tranquil escape will find the town center ideal. The quiet surroundings, opportunities for scenic walks along the creek, and the charm of the historic architecture create a great backdrop for a relaxing getaway. ### When is the best time to go to Old Appleton? > Spring, particularly April and May, brings comfortable temperatures and blooming scenery, making it ideal for exploring the historic sites and natural beauty without the summer heat. This season is superb for couples who enjoy leisurely walks and scenic drives through the countryside. > > > Similarly, the fall months of September and October offer crisp air, colorful foliage, and comfortable conditions. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Old Appleton hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Old Appleton hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Frohna Hotels ](https://www.expedia.com/Frohna-Hotels.d553248634983521632.Travel-Guide-Hotels) - [Friedheim Hotels ](https://www.expedia.com/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Fruitland Hotels ](https://www.expedia.com/Fruitland-Hotels.d553248635975866670.Travel-Guide-Hotels) - [Perryville Hotels ](https://www.expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Sedgewickville Hotels ](https://www.expedia.com/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Hotels near Perryville Country Club ](https://www.expedia.com/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Perryville ](https://www.expedia.com/Perryville-Cabins.d6134448-aaCabins.Travel-Guide-Accommodation) - [Motels in Perryville ](https://www.expedia.com/Perryville-Motels.d6134448-aaMotels.Travel-Guide-Accommodation) - [Historic Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Historic-Hotel.0-0-d6134448-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Pet-Friendly-Hotel.0-0-d6134448-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Apartments in Perryville ](https://www.expedia.com/Perryville-Apartments.d6134448-aaApartments.Travel-Guide-Accommodation) - [Hotels with Hot Tubs in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Hot-Tubs.0-0-d6134448-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Cheap-Hotels.0-0-d6134448-tCheapHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Winery-Hotel.0-0-d6134448-tWineryHotel.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Perryville ](https://www.expedia.com/Perryville-Hotels-Spa-Hotel.0-0-d6134448-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Wedding-Hotels.0-0-d6134448-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Indoor-Pool.0-0-d6134448-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Hotels with an Outdoor Pool in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Outdoor-Pool.0-0-d6134448-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels) - [Golf Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Golf-Hotel.0-0-d6134448-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with Bars in Perryville ](https://www.expedia.com/Perryville-Hotels-Bar-Hotel.0-0-d6134448-tBarHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotel-With-Pool.0-0-d6134448-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Non-Smoking Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Smoke-Free-Hotels.0-0-d6134448-tSmokeFreeHotels.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Adjoining-Rooms.0-0-d6134448-tHotelswithAdjoiningRooms.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Facilities in Perryville ](https://www.expedia.com/Perryville-Hotels-Hotels-With-Laundry-Facilities.0-0-d6134448-tHotelswithLaundryFacilities.Travel-Guide-Filter-Hotels) - [Hotels near National Shrine of Our Lady of the Miraculous Medal ](https://www.expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Hotels.0-l553248621561876731-0.Travel-Guide-Filter-Hotels) - [Hotels near Steele Crest Winery ](https://www.expedia.com/Steele-Crest-Winery-Hotels.0-l553248621554122992-0.Travel-Guide-Filter-Hotels) - [Hotels near Missouri's National Veterans Memorial ](https://www.expedia.com/Missouris-National-Veterans-Memorial-Hotels.0-l620724250067501056-0.Travel-Guide-Filter-Hotels) - [Jackson Hotels ](https://www.expedia.com/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Hotels near Litz Park ](https://www.expedia.com/Litz-Park-Hotels.0-l553248621554122991-0.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Jackson ](https://www.expedia.com/Jackson-Cabins.d55765-aaCabins.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Jackson ](https://www.expedia.com/Jackson-Hotels-Pet-Friendly-Hotel.0-0-d55765-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Extended Stay Hotels in Jackson ](https://www.expedia.com/Jackson-Hotels-Extended-Stay-Hotels.0-0-d55765-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [B&B in Jackson ](https://www.expedia.com/Jackson-Bed-And-Breakfast.d55765-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with an Indoor Pool in Jackson ](https://www.expedia.com/Jackson-Hotels-Hotels-With-Indoor-Pool.0-0-d55765-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Casino Hotels in Jackson ](https://www.expedia.com/Jackson-Hotels-Casino-Hotel.0-0-d55765-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Jackson ](https://www.expedia.com/Jackson-Hotels-Hotels-With-Hot-Tubs.0-0-d55765-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Jackson ](https://www.expedia.com/Jackson-Hotels-Cheap-Hotels.0-0-d55765-tCheapHotels.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Jackson ](https://www.expedia.com/3Star-Jackson-Hotels.s30-0-d55765.Travel-Guide-Filter-Hotels) - [Hotels with Restaurants in Jackson ](https://www.expedia.com/Jackson-Hotels-Hotels-With-Restaurants.0-0-d55765-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Hotels with Bars in Jackson ](https://www.expedia.com/Jackson-Hotels-Bar-Hotel.0-0-d55765-tBarHotel.Travel-Guide-Filter-Hotels) - [Motels in Jackson ](https://www.expedia.com/Jackson-Motels.d55765-aaMotels.Travel-Guide-Accommodation) - [Hotels with Suites in Jackson ](https://www.expedia.com/Jackson-Hotels-Hotel-Suites.0-0-d55765-tHotelSuites.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Jackson ](https://www.expedia.com/Jackson-Hotels-Hotels-With-Kitchens.0-0-d55765-tHotelswithKitchens.Travel-Guide-Filter-Hotels) - [Family Hotels in Jackson ](https://www.expedia.com/Jackson-Hotels-Family-Hotel.0-0-d55765-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Jackson ](https://www.expedia.com/Jackson-Hotels-Spa-Hotel.0-0-d55765-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Jackson ](https://www.expedia.com/Jackson-Hotels-Hotel-With-Pool.0-0-d55765-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels near Hunter Valley Winery ](https://www.expedia.com/Hunter-Valley-Winery-Hotels.0-l553248621532655783-0.Travel-Guide-Filter-Hotels) - [Hotels near Lazy L Safari Park ](https://www.expedia.com/Lazy-L-Safari-Park-Hotels.0-l553248621532655782-0.Travel-Guide-Filter-Hotels) - [Hotels near Trail of Tears State Park ](https://www.expedia.com/Trail-Of-Tears-State-Park-Hotels.0-l553248621532655784-0.Travel-Guide-Filter-Hotels) - [Hotels near Cape Girardeau Conservation Nature Center ](https://www.expedia.com/Cape-Girardeau-Conservation-Nature-Center-Hotels.0-l553248621532655773-0.Travel-Guide-Filter-Hotels) - [Cape Girardeau Hotels ](https://www.expedia.com/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Hotels near Cape Splash Family Aquatic Center ](https://www.expedia.com/Cape-Splash-Family-Aquatic-Center-Hotels.0-l553248621532655772-0.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University ](https://www.expedia.com/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Hotels near Cape Rock Park ](https://www.expedia.com/Cape-Rock-Park-Hotels.0-l553248621532655781-0.Travel-Guide-Filter-Hotels) - [Hotels near Isle Casino Cape Girardeau ](https://www.expedia.com/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Cape Girardeau ](https://www.expedia.com/Cape-Girardeau-Hotels-Cheap-Hotels.0-0-d820-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near eDen Spa & Salon ](https://www.expedia.com/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Cape Girardeau ](https://www.expedia.com/Cape-Girardeau-Hotels-Casino-Hotel.0-0-d820-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Cape Girardeau ](https://www.expedia.com/Cape-Girardeau-Hotels-Pet-Friendly-Hotel.0-0-d820-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Flights from Frohna ](https://www.expedia.com/lp/flights/553248634983521632/flights-from-frohna) - [Flights to Perryville ](https://www.expedia.com/Cheap-Flights-To-Perryville.d6134448.Travel-Guide-Flights) - [Flights from Perryville ](https://www.expedia.com/lp/flights/6134448/flights-from-perryville) - [Flights to Jackson ](https://www.expedia.com/Cheap-Flights-To-Jackson.d55765.Travel-Guide-Flights) - [Flights from Jackson ](https://www.expedia.com/lp/flights/55765/flights-from-jackson) - [Flights to Cape Girardeau ](https://www.expedia.com/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights) - [Perryville Country Club ](https://www.expedia.com/Perryville-Country-Club-Perryville.d553248621564822920.Vacation-Attraction) - [Visit Perryville ](https://www.expedia.com/Perryville.dx6134448) - [Perryville Vacations ](https://www.expedia.com/Perryville.d6134448.Destination-Travel-Guides) - [National Shrine of Our Lady of the Miraculous Medal ](https://www.expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Perryville.d553248621561876731.Vacation-Attraction) - [Steele Crest Winery ](https://www.expedia.com/Steele-Crest-Winery-Jackson.d553248621554122992.Vacation-Attraction) - [Missouri's National Veterans Memorial ](https://www.expedia.com/Missouris-National-Veterans-Memorial-Perryville.d620724250067501056.Vacation-Attraction) - [Litz Park ](https://www.expedia.com/Litz-Park-Jackson.d553248621554122991.Vacation-Attraction) - [Visit Jackson ](https://www.expedia.com/Jackson.dx55765) - [Jackson Vacations ](https://www.expedia.com/Jackson.d55765.Destination-Travel-Guides) - [Hunter Valley Winery ](https://www.expedia.com/Hunter-Valley-Winery-Cape-Girardeau.d553248621532655783.Vacation-Attraction) - [Lazy L Safari Park ](https://www.expedia.com/Lazy-L-Safari-Park-Cape-Girardeau.d553248621532655782.Vacation-Attraction) - [Trail of Tears State Park ](https://www.expedia.com/Trail-Of-Tears-State-Park-Missouri.d553248621532655784.Vacation-Attraction) - [Cape Splash Family Aquatic Center ](https://www.expedia.com/Cape-Splash-Family-Aquatic-Center-Cape-Girardeau.d553248621532655772.Vacation-Attraction) - [Cape Rock Park ](https://www.expedia.com/Cape-Rock-Park-Cape-Girardeau.d553248621532655781.Vacation-Attraction) - [Southeast Missouri State University ](https://www.expedia.com/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) - [Isle Casino Cape Girardeau ](https://www.expedia.com/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction) - [Visit Cape Girardeau ](https://www.expedia.com/Cape-Girardeau.dx820) - [Car rentals near Friedheim ](https://www.expedia.com/Car-Rentals-In-Friedheim.d3000349372.Car-Rental-Guide) - [Car rentals near Longtown ](https://www.expedia.com/Car-Rentals-In-Longtown.d553248634983409987.Car-Rental-Guide) - [Car rentals near Oak Ridge ](https://www.expedia.com/Car-Rentals-In-Oak-Ridge.d553248634983311120.Car-Rental-Guide) - [Car rentals near Pocahontas ](https://www.expedia.com/Car-Rentals-In-Pocahontas.d553248634983366486.Car-Rental-Guide) - [Car rentals near Fruitland ](https://www.expedia.com/Car-Rentals-In-Fruitland.d553248635975866670.Car-Rental-Guide) - [Car rentals near Perryville ](https://www.expedia.com/Car-Rentals-In-Perryville.d6134448.Car-Rental-Guide) - [Hertz Rental Cars in Perryville ](https://www.expedia.com/Hertz-Car-Rentals-In-Perryville.d6134448-c40.Car-Rental-Guide-Suppliers) - [Car rentals near Jackson ](https://www.expedia.com/Car-Rentals-In-Jackson.d55765.Car-Rental-Guide) - [Priceless Car Rental Rental Cars in Jackson ](https://www.expedia.com/Priceless-Car-Rental-Car-Rentals-In-Jackson.d55765-c1060.Car-Rental-Guide-Suppliers) - [Car rentals near Belgique ](https://www.expedia.com/Car-Rentals-In-Belgique.d553248635975859150.Car-Rental-Guide) - [Car rentals near Lithium ](https://www.expedia.com/Car-Rentals-In-Lithium.d553248634983113033.Car-Rental-Guide) - [Discount Car Rentals Rental Cars in Lithium ](https://www.expedia.com/Discount-Car-Rentals-Car-Rentals-In-Lithium.d553248634983113033-c11.Car-Rental-Guide-Suppliers) - [Car rentals near Gordonville ](https://www.expedia.com/Car-Rentals-In-Gordonville.d553248634983145277.Car-Rental-Guide) - [Car rentals near Isle Casino Cape Girardeau ](https://www.expedia.com/Car-Rentals-In-Isle-Casino-Cape-Girardeau.d553248621532655780.Car-Rental-Guide) - [Hertz Rental Cars in Cape Girardeau ](https://www.expedia.com/Hertz-Car-Rentals-In-Cape-Girardeau.d820-c40.Car-Rental-Guide-Suppliers) - [Enterprise Rental Cars in Cape Girardeau ](https://www.expedia.com/Enterprise-Car-Rentals-In-Cape-Girardeau.d820-c15.Car-Rental-Guide-Suppliers) - [Car rentals near Cape Girardeau ](https://www.expedia.com/Car-Rentals-In-Cape-Girardeau.d820.Car-Rental-Guide) - [Perryville Vacation Rentals ](https://www.expedia.com/Perryville-Vacation-Rentals.d6134448.Travel-Guide-VacationRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app